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blockers in Medical Technology

New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients

... can occur or get worse in people who use TNF blockers like SIMPONI(TM). Your doctor will monitor you ... legs or feet. Rarely, people using TNF blockers can have nervous system problems such as multiple ... or paleness. Rarely, people using TNF blockers have developed lupus-like symptoms. Tell your ...

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

... can occur or get worse in people who use TNF blockers like SIMPONI(TM). Your doctor will monitor you ... legs or feet. Rarely, people using TNF blockers can have nervous system problems such as multiple ... or paleness. Rarely, people using TNF blockers have developed lupus-like symptoms. Tell your ...

Research Finding Could Revolutionize Asthma Treatment

... Use of Beta blockers May Have Long-Term Benefits SAN FRANCISCO, ... Foundation (AAF), said, "Drugs known as beta blockers have long been used to treat high blood pressure. ... and his colleagues showing that low doses of beta blockers improved asthma in mice. Expanding on his ...

Study Shows Leconotide, an Investigative Calcium Channel Blocker, Has Potential as a Selective, Efficacious, Non-Opioid Pain Treatment

... has been seen in studies of other calcium channel blockers used for treating pain. It was ... were given injections of two calcium channel blockers (leconotide or ziconotide) alone and in ... snail Conus Catus. About Calcium Channel blockers Every cell in the body is enclosed by a ...

New Study Shows BENICAR(R) (olmesartan medoxomil) Reverses Blood Vessel Damage Independent of Blood Pressure Lowering

... evidence for the role of angiotensin receptor blockers in preventing or reversing vascular damage ... ACE inhibitors or other angiotension II receptor blockers (ARBs) in the reversal of vascular hypertrophy in ... Lewis, EJ. The Role of Angiotensin II Receptor blockers in Preventing the Progression of Renal ...

Generic Substitutes Less Effective/Safe Than Branded Medications in Treating Lower Urinary Tract Symptoms

... Urological Association (AUA) showing that generic substitutes for alpha blockers and 5-alpha reductase inhibitors (5-ARIs), two classes of medications used ... Over eight weeks, the study tested 212 men taking branded alpha blockers or 5-ARIs with an average age of 64, who were switched to generic ...

CIMZIA(R) (Certolizumab Pegol) Provides Long-Term Benefit Without Dose Escalation in Crohn's Disease Patients

... The data suggest that based on standard regimens for each of the TNF alpha blockers for CD, CIMZIA may be less costly than the two biologics studied. About ... reduces the risk of reactivation in patients receiving treatment with TNF blockers such as CIMZIA. However, active tuberculosis has developed in patients ...

Vantia Therapeutics' Lead Candidate VA106483 Demonstrates Positive Anti-diuretic Effect in Phase IIa Trial in Nocturia

... at least 70% of BPH patients complaining of nocturia. Whilst some symptoms of BPH are successfully addressed by the standard BPH therapies of alpha blockers and 5-alpha reductase inhibitors, nocturia remains inadequately treated. With estimates putting the number of BPH/nocturia sufferers at 55 million in ...

Research: Popular Diabetes Medications Associated with Increase in Bone Fractures

... clopidogrel alone. Communications with Doctors Increase Use of Key Medications in Diabetes Ace Inhibitors (ACE-I) and angiotensin receptor blockers (ARB), two major categories of antihypertensives, appear to have unique clinical benefits compared to other antihypertensive therapies. New Medco ...

New Data Shows AZOR(R) (amlodipine and olmesartan medoxomil) Significantly Improves 24-Hour Ambulatory Blood Pressure

... on starting calcium channel blocker therapy or at the time of dosage increase. Congestive Heart Failure In general, calcium channel blockers should be used with caution in patients with heart failure. Impaired Renal Function In studies of ACE inhibitors in patients with unilateral ...

Vantia Therapeutics' Pipeline Continues to Mature

... at least 70% of BPH patients complaining of nocturia. Whilst some symptoms of BPH are successfully addressed by the standard BPH therapies of alpha blockers and 5-alpha reductase inhibitors, nocturia remains inadequately treated. With estimates putting the number of BPH/nocturia sufferers at 55 million in ...

Advances in Science and Treatment of Pain Presented at 25th Annual American Academy of Pain Medicine Meeting January 28 - 31, 2009

... AM HAST Coral Ballroom Foyer, Hilton Hawaiian Village Authors present Jan. 29 from 3:30-5 PM and Jan. 30 from 9-10 AM Calcium Channel blockers Compared for Neuropathic Pain, Poster 181 Addictive Qualities of Cannabinoid Medication, Poster 193 Tramadol Outcomes, Poster 197 Safety, ...

CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years

... Anti-tuberculosis treatment of patients with latent tuberculosis infection reduces the risk of reactivation in patients receiving treatment with TNF blockers such as CIMZIA. However, active tuberculosis has developed in patients receiving CIMZIA whose tuberculin test was negative. Evaluate patients for ...

Minster Pharmaceuticals Plc Announces Positive Results from Phase II Trial of Migraine with Aura

... a result of investment by GSK. Tonabersat is the leading compound in an exciting new class of selective drugs designated as neuronal gap junction blockers and offers the potential to prevent the onset of migraine as a preferred alternative to acute treatment. Sabcomeline, a muscarinic partial agonist, ...

New Findings Show Efficacy of REMICADE(R) Compared With Azathioprine in Treatment of Crohn's Disease According to First-of-its Kind Study

... region where histoplasmosis or coccidioidomycosis is common. Reports of a type of blood cancer called lymphoma in patients on REMICADE or other TNF blockers are rare but occur more often than expected for people in general. People who have been treated for rheumatoid arthritis, Crohn's disease, ankylosing ...

CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohn's Patients

... Anti-tuberculosis treatment of patients with latent tuberculosis infection reduces the risk of reactivation in patients receiving treatment with TNF blockers such as CIMZIA. However, active tuberculosis has developed in patients receiving CIMZIA whose tuberculin test was negative. Evaluate patients for ...

New Data Shows Prescription Omega-3 Acid Ethyl Esters Reduced the Incidence of Death in Heart Failure Patients

... admission, patients were already on optimal therapy for heart failure e.g. 94 percent of patients were on ACE Inhibitors / ARBs, 65 percent on beta blockers and 39 percent on spironolactone. Co-primary endpoints were time to death, and time to death or admission to hospital for cardiovascular reasons. ...

Pediatric Researchers Find Possible 'Master Switch' Gene in Juvenile Arthritis

... leads to arthritis," said Behrens, a pediatric rheumatologist at Children's Hospital. "We currently use medicines called tumor necrosis factor blockers to treat children with JIA. However, not all children respond to these drugs, and other children may develop severe allergic reactions and other side ...

CV Therapeutics Announces Archives of Internal Medicine Publication of Study Showing 20 Percent of Heart Attack Patients in Premier Registry Experienced Angina at One Year

... reported that in patients with angina after one year, 87.9 percent were not taking calcium channel blockers, 30.8 percent were not taking beta blockers and 48.6 percent were not taking nitrates. "After patients survive a heart attack, a primary goal of treatment is to minimize their angina and ...

Pivotal Pulmonary Arterial Hypertension Study Published in The Lancet Concludes That Bosentan (Tracleer(R)) Demonstrates Benefits in Patients With Mildly Symptomatic WHO Functional Class II Disease

... arterial hypertension. NEJM 2002; 346: 896-903 (BREATHE-1). 4. Sitbon O, Humbert M, Jais X et al. Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation 2005; 111: 3105-3111 5. D'Alonzo GE, Barst RJ, Ayres SM et al. Survival in patients ...

Cimzia(R) Provides Long-Term Efficacy with Stable Dosing in Crohn's Disease

... Anti-tuberculosis treatment of patients with latent tuberculosis infection reduces the risk of reactivation in patients receiving treatment with TNF blockers such as Cimzia(R). However, active tuberculosis has developed in patients receiving Cimzia(R) whose tuberculin test was negative. Evaluate patients ...

New Analysis Shows Efficacy of REMICADE(R) in Treatment of Ulcerative Colitis in Patients with Recent Disease Onset or Long-Standing Disease

... region where histoplasmosis or coccidioidomycosis is common. Reports of a type of blood cancer called lymphoma in patients on REMICADE or other TNF blockers are rare but occur more often than expected for people in general. People who have been treated for rheumatoid arthritis, Crohn's disease, ankylosing ...

Azor(TM) Reduces Blood Pressure in Difficult to Treat Special Populations

... infarction on starting calcium channel blocker therapy or at the time of dosage increase. Congestive Heart Failure In general, calcium channel blockers should be used with caution in patients with heart failure. Impaired Renal Function In studies of ACE inhibitors in patients with unilateral or ...

Landmark ONTARGET(TM) Trial Demonstrates Micardis(R) is Equally Effective as Ramipril, with Fewer Discontinuations, in a Broad High-Risk Cardiovascular Population

... a large group (8,542) of high-risk patients who were already receiving standard care such as statins to lower cholesterol, antiplatelet therapy, beta blockers and other antihypertensives.(3) Telmisartan treatment led to fewer discontinuations than treatment with ramipril, a widely used ACE inhibitor.(1) ...

REMICADE-Treated Patients Experienced Rapid and Substantial Improvement in Psoriasis in Critical Regions of Body

... region where histoplasmosis or coccidioidomycosis is common. Reports of a type of blood cancer called lymphoma in patients on REMICADE or other TNF blockers are rare but occur more often than expected for people in general. People who have been treated for rheumatoid arthritis, Crohn's disease, ankylosing ...

Inverseon Announces Positive Phase IIa Asthma Study

... data the Inverseon approach is very consistent. In our animal asthma models chronic dosing of beta inverse agonists -- which are a subset of beta blockers -- resulted in up-regulation of lung beta receptors, while reducing inflammation and airway hyper-responsiveness. The fact that we are seeing some of ...

CV Therapeutics' Anti-Ischemic Agent Ranexa(R) Significantly Reduces HbA1c and Other Markers of Diabetes in MERLIN TIMI-36

... in the MERLIN TIMI-36 study received current standard therapy, with approximately 96 percent of patients on aspirin, approximately 89 percent on beta blockers and approximately 82 percent on statins. Approximately 59 percent of study participants received coronary angiography during their initial ...

UPDATE: Nebivolol Lowers Blood Pressure in African Americans With Stage I-II Hypertension as Demonstrated in a Study Published in the Journal of Clinical Hypertension

... supports nebivolol's ability to lower blood pressure in a broad range of patients, including patients that are typically hard to treat with beta blockers such as African Americans," says Neil Shusterman, MD, Senior Vice President, Clinical Development of Forest Research Institute. "In addition to these ...

Nebivolol Lowers Blood Pressure in African Americans With Stage I-II Hypertension as Demonstrated in a Study Published in the Journal of Clinical Hypertension

... supports nebivolol's ability to lower blood pressure in a broad range of patients, including patients that are typically hard to treat with beta blockers such as African Americans," says Neil Shusterman, MD, Senior Vice President, Clinical Development of Forest Research Institute. "In addition to these ...

Younger Adults Increasingly Treated for Heart Disease-related Conditions

... others, medications may be needed. The most common medications used to treat high cholesterol are statins. To treat hypertension, diuretics, beta- blockers and ACE inhibitors are often prescribed. Medco's Specialist Pharmacists Medco has developed an innovative approach to help improve and ...

Ozarelix Phase 2 Data Presented at 29th Congress of the Societe Internationale d'Urologie

... Current treatment options have limited efficacy, leading to inadequate compliance. Medications currently available belong to two classes: alpha blockers (such as FLOMAX(R)[1], CARDURA(R)[2] and HYTRIN(R)[3]) which relax the muscles in the neck of the bladder and in the prostate, but have no direct ...

Par Pharmaceutical Begins Shipment of Additional Dosage Strength of Generic TOPROL-XL(R)

... have bronchospastic disease, diabetes, thyrotoxicosis, or peripheral vascular disease; who are undergoing major surgery, or who take calcium channel blockers of the verapamil and diltiazem type. There is a risk of worsening cardiac failure during up-titration of the dose of metoprolol succinate extended ...

New Study Shows That telmisartan has Greater Renoprotective Potential Thanlosartan in Hypertensive Patients With Type 2 Diabetes

... studies to compare the protective potential of two angiotensin receptor blockers in hypertensive patients with diabetic nephropathy, was presented at the ... (6) Bakris G et al. Comparative long term effects of two AT1 receptor blockers on proteinuria in patients with type-2 diabetes and overt nephropathy and ...

New Data Presented on Micardis (Telmisartan) Tablets in Hypertensive Patients With Type 2 Diabetes

... AMADEO*, one of a series of studies comparing two angiotensin receptor blockers (ARBs) in hypertensive patients with diabetic nephropathy, were presented ... G et al. Comparative long term effects of two AT1 receptor blockers on proteinuria in patients with type-2 diabetes and overt ...

Survival Data Available from Erbitux Study in First-Line Treatment of Advanced Head and Neck Cancer

... to address the medical needs of patients with a variety of cancers. The Company's research and development programs include growth factor blockers and angiogenesis inhibitors. ImClone Systems' strategy is to become a fully integrated biopharmaceutical company, taking its development programs ...

Survival Data Available From Erbitux Study in First-Line Treatment of Advanced Head and Neck Cancer

... to address the medical needs of patients with a variety of cancers. The Company's research and development programs include growth factor blockers and angiogenesis inhibitors. ImClone Systems' strategy is to become a fully integrated biopharmaceutical company, taking its development programs ...

Data Available from Erbitux Phase III Study in First-Line Treatment of Advanced Pancreatic Cancer

... to address the medical needs of patients with a variety of cancers. The Company's research and development programs include growth factor blockers and angiogenesis inhibitors. ImClone Systems' strategy is to become a fully integrated biopharmaceutical company, taking its development programs ...

Randomized Phase III Trial Showed Erbitux Significantly Improved Secondary Endpoints of Progression-Free Survival and Disease Control in Metastatic Colorectal Cancer Patients

... to address the medical needs of patients with a variety of cancers. The Company's research and development programs include growth factor blockers and angiogenesis inhibitors. ImClone Systems' strategy is to become a fully integrated biopharmaceutical company, taking its development programs ...

Data Presented at AACR Meeting Show Peregrine's Bavituximab Equivalent Can Generate Curative Immune Responses as Part of a Vaccine-Like Regimen in Preclinical Models of Aggressive Brain Cancer

... to the tumor cells and resulting in tumor cell death. PS is also thought to play a role in suppressing the body's immune response to cancer. PS blockers may have the potential to help reverse this suppression and enable the immune system to attack the cancer more effectively. As an ...
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