Bacteria in Medical Technology

Awardees for the 2009 Young Investigator Grant for Probiotics Research Announced

... of Novel Oligopeptides Produced by Transgenic bacteria on Intestinal Injury Due to C. difficile ... a collection of approximately 3,500 lactic bacteria strains or "cultures." In addition to taste and ... as genomics and robotics to select the probiotic bacteria of the future is carefully studying it. For more ...

Is Obesity an Oral Bacterial Disease?

... have focused on the possible role of oral bacteria as a potential direct contributor to obesity. ... data suggests that the composition of salivary bacteria changes in overweight women. It seems likely ... of future research, is the possibility that oral bacteria may participate in the pathology that leads to ...

Rendell Administration Announces Health Research Grants From Tobacco Settlement Funds

... been estimated that more than 70 percent of the bacteria that cause health care infections have resistance ... admission. Many of these infections are caused by bacteria resistant to most, if not all, currently ... Clostridium difficile ( C. difficile ), other bacteria that have developed drug resistance, also cause ...

Nanoemulsion Kills Highly Resistant Bacteria Found in Patients With Cystic Fibrosis

... kills the highly resistant strains of bacteria that cause chronic illness and death among ... they represent a new model for treating resistant bacteria that lead to pulmonary failure in patients ... airways with sufficient strength to subdue the bacteria or to penetrate the thick sputum and bacterial ...

British Midlands University Announces Use of Gene Technology to Fight Lethal Hospital Acquired Infection

... the function of genes in a 'super' strain of the bacteria Clostridium difficile, to discover why it causes ... disease. Currently, scientists know that the bacteria cause disease by sticking to epithelial cells of ... is very little known about the ways in which the bacteria operate and why the strain should be more severe ...

MicroPhage Successfully Completes Beta Trial for Rapid MRSA Test

... assay to identify Staphylococcus aureus (staph) bacteria and determine methicillin resistance (MRSA) or ... and had an excellent detection rate for S. aureus bacteria of 93 percent while also determining methicillin ... shows if the sample is infected with staph bacteria and the other measures antibiotic ...

Rib-X Pharmaceuticals Reports Positive Top-Line Results from Phase 2 Study of Delafloxacin

... against quinolone resistant Gram-positive bacteria including MRSA. The compound has been shown to be ... including quinolone-resistant Gram-positive bacteria and MRSA. Currently in Phase 2 trials, Rib-X is ... active against multi-drug resistant Gram-negative bacteria and the Rx-02 discovery program is focused on ...

New Data Show In Vitro Potency of Doripenem Against Resistant Bacteria

... Enterobacteriaceae is a large group of bacteria that can cause infections of the digestive tract or other organs of the body and includes common bacteria strains such as E. coli. These new data were ... To reduce the development of drug-resistant bacteria and maintain the effectiveness of DORIBAX and ...

'Friendly' Bacteria Can Benefit Health Throughout the Lifecycle

... which can promote healthy colonization of bacteria in the gut during this time, leading to enhanced ... systems, there are many more "friendly" bacteria than "bad" bacteria. If this balance ... probiotics and the use of intestinal bacteria in human health around the world. The company has ...

Copper Eliminates Resistant Hospital Germs in a Worldwide Field Test

... Germany, August 22 /PRNewswire/ -- - Dangerous bacteria Infect Three Million People in Europe Every Year ... opponents are dangerous, antibiotic-resistant bacteria (MRSA), with which more and more patients ... doubt that copper surfaces can efficiently kill bacteria and other germs," Prof. Dr. Dietrich H. Nies, ...

Study Shows Use of AdvanDx's PNA FISH(TM) Test was Associated with an 82% Reduction in Intensive Care Unit Mortality Rates from Staphylococcus aureus Bloodstream Infections

... Bloodstream infections due to Staphylococcus bacteria are a leading cause of hospital-acquired ... results and information on the identified bacteria were reported directly to the treating clinicians ... blood (i.e. a blood culture) turns positive with bacteria and yeast. Rapid and accurate identification of ...

Bad News to Bad Bugs: Northern Antibiotics Develops Novel Polymyxins With Reduced Toxicity

... emergence of multidrug-resistant Gram-negative bacteria has necessitated the use of polymyxins as the ... active against multidrug-resistant Gram-negative bacteria is urgent. Enteric bacteria are responsible for more than 80% of all the ...

June 2008 Mayo Clinic Women's HealthSource Highlights Shingles Vaccine for Pain Prevention, Tips to Avoid Antibiotic Resistant Infections, and Benefits of Broad Genetic Testing

... antibiotic-resistant infections Superbugs -- bacteria that are resistant to many commonly ... care settings for years. In this environment, the bacteria is spread from one patient to another via the ... care provider to take a culture to confirm what bacteria are present before you are given an antibiotic. ...

Cequent Pharmaceuticals' Johannes Fruehauf, MD, Ph.D., to be Featured Speaker at RNAi World Congress in Boston - May 2, 2008

... process, we modify live, nonpathogenic E. coli bacteria to produce and deposit mediators of RNA ... directly into the target cells. The nonpathogenic bacteria are subsequently degraded by the host cells ... safely and effectively, using non-pathogenic bacteria as an engine to produce and deliver RNAi ...

New Approach to Treating Anthrax Significantly Improves Survival Rates in Pivotal Efficacy Studies

... not effective against the deadly toxins that the bacteria produce -- the real culprits in anthrax- related ... studies were rapidly cleared of anthrax toxin and bacteria following intravenous administration of a single ... the anthrax toxins. Research has shown that the bacteria produce protective antigen, the key facilitator ...

National Wrestling Coaches Association Teams Up With CSG/SportsCoatings(TM)

... solution to odor and infection causing bacteria for years," said CSG/SportsCoatings CEO Craig ... wrestling equipment and protective gear from bacteria mold and fungi common in wrestling is something ... that's using a proven technology to control bacteria is a great fit for our organization, considering ...

Cantel Medical Corp.'s Crosstex Subsidiary Addresses School MRSA Concerns With SaniTyze(TM) Brand Hand Sanitizer and Sanitex(R) Surface Disinfecting Line of Products

... against the spread of MRSA and other infectious bacteria and viruses. While school officials recognize ... "With all the different strains of bacteria and viruses out there, product claims against ... by the EPA as effective against a number of bacteria and viruses, including MRSA. Those claims are ...

Paratek Pharmaceuticals Announces the Close of $40 Million Private Placement to Finance Programs to Combat MRSA Infections

... that have been shown to work against susceptible bacteria found in most common infections, as well as antibiotic resistant bacteria such as MRSA, vancomycin-resistant Enterococci ... hospital and community settings due to resistant bacteria such as MRSA and have determined that Paratek's ...

New Data Show Ceftobiprole as Effective as Combination Therapy in Treating Patients with Diabetic Foot Infections

... . + Gram-positive indicates a group of bacteria that become blue when the bacterial cells are ... identify the type of bacteria. Some Gram-positive bacteria may cause serious infections. ++ Gram-negative indicates a group of bacteria that become red when the bacterial cells are ...

Replidyne's Investigational Antibacterial Agent REP3123 Prevents Toxin Production in Clostridium difficile

... act by means other than simply eradicating the bacteria may be very helpful and should be studied," ... on inhibiting toxin production of C. difficile bacteria is very important and equally as exciting." "C. ... agent REP3123 targets Gram-positive C. difficile bacteria and related diseases. In preclinical studies, ...

New Data Show Ceftobiprole as Effective as Combination Therapy in Treating Patients With Complicated Skin Infections, Including MRSA

... . * Gram-negative indicates a group of bacteria that become red when the bacterial cells ... the type of bacteria. Some Gram- negative bacteria may cause serious infections. ** Gram-positive indicates a group of bacteria that become blue when the bacterial cells ...

New Data Show Doripenem as Effective as Commonly Used Therapies in Treating Hospital-Acquired Pneumonias

... aeruginosa, which is one of the most difficult bacteria to treat," said Michael Niederman, ... New York. "Additionally, these troubling bacteria demonstrated a low rate of resistance to ... study demonstrated that a greater proportion of bacteria were resistant to piperacillin/tazobactam ...

U. of Md. Researchers to Develop Devices to Revolutionize Drug Research

... of infections in the body. In quorum sensing, bacteria cells communicate with each other to form ... interrupts quorum sensing will not stimulate the bacteria to evolve and become resistant, as ... measurements of biofilm (a coating created by bacteria that is the first sign of an infection). These ...

Keeping the Data Center Clean: ATEN Launches Industry-First KVM Switches with Antimicrobial Nanocoating to Protect Products from Bacteria Surviving on Surfaces

... The average desk harbors 400 times more bacteria than the average toilet seat, and some of the ... their desktops which can lead to the spread of bacteria in the data center. As a result, the presence of ... mechanisms to deactivate enzymes and proteins of bacteria from surviving on the surface of the product. The ...

Boston University Biomedical Engineers Find Chink in Bacteria's Armor

... a previously unknown chain of events occurring in bacteria that opens to door to new avenues of research. ... effect and the emergence of antibiotic-resistant bacteria could be limited. "Importantly, we showed that ... the cell." In addition to potentially making bacteria more vulnerable to current drugs, this finding ...

Alcon Commences Phase 2 Clinical Trial of NovaBay's NVC-422 for Viral Conjunctivitis

... to clear on its own. Bacterial conjunctivitis is caused by a variety of bacteria and is largely treated with topically applied antibiotic eye drops. ... and fungi. They also have been demonstrated to be effective against bacteria in biofilms, which render most antibiotics ineffective. Aganocides have a ...

Optimer Pharmaceuticals Presents Results From Fidaxomicin Phase 3 Study for the Treatment of Clostridium difficile Infection

... but more selective therapy that is less damaging to the normal intestinal bacteria that protect against recurrence of CDI." Additional findings also ... that disrupt normal gastrointestinal (gut) flora, allowing C. difficile bacteria to flourish. Current therapeutic options for CDI include ...

Rib-X Pharmaceuticals Novel Antibiotic Delafloxacin Named One of R&D Directions 100 Great Investigational Drugs of 2009

... demonstrated by delafloxacin against a wide range of highly-resistant bacteria may offer the medical community a much needed treatment alternative for a ... classes of antibiotics active against multi-drug resistant Gram-negative bacteria and the Rx-02 discovery program is focused on developing an IV/oral ...

Children and Orthopaedic Surgical Emergencies

... bones and particularly the soft tissue around the bone, that are caused by bacteria which is resistant to many antibiotics," explains Dr. Martin Herman, M.D., ... University College of Medicine. The infections usually result from bacteria in the bloodstream, which settle into the child's bone or joint and within ...

Sanofi Pasteur Starts a Phase II Study of a Vaccine Against Clostridium Difficile

... of antibiotic treatment, and a patient ingests C. difficile spores, the bacteria can multiply and release the two toxins, which cause gastrointestinal ... CDI. Hospital-acquired infections caused by C. difficile bacteria are a considerable problem in many industrialized countries, including the ...

Human Genome Sciences Begins Delivery of First-in-Class Anthrax Treatment to U.S. Strategic National Stockpile

... bacteria, they are not effective against the deadly toxins that the bacteria produce. ABthrax targets anthrax toxins after they are released by the bacteria into the blood and tissues. In an inhalation anthrax attack, people may ...

Cequent to Present First Proof of Activity of an Oral RNAi Drug in Non-Human Primates at February Keystone Conference

... and no gross or histopathologic abnormalities noted. Orally administered bacteria expressing short hairpin RNA (shRNA) against beta-catenin significantly ... disease-causing genes safely and effectively, using non-pathogenic bacteria as an engine to produce and deliver RNAi directly into cells. It is based ...

Rib-X Pharmaceuticals Reports Positive Phase 2 Study Results for Next Generation Oxazolidinone at 2008 ICAAC/IDSA Joint Meeting

... radezolid was approximately four times more potent than linezolid against bacteria cultured from subjects in the study, including against ... classes of antibiotics active against multi-drug resistant Gram-negative bacteria and the Rx-02 discovery program is focused on developing an IV/oral ...

Mpex Pharmaceuticals Presents New Data on MP-376 in Cystic Fibrosis

... potency of MP-376 compared to other agents against gram positive bacteria commonly found in CF patients. -- Resistance: in an in vitro model of ... antibiotics to overcome or directly inhibit the molecular mechanisms in bacteria responsible for antibiotic resistance. Mpex's most advanced product ...

Mpex Initiates a Phase 2 Clinical Trial of Aerosol MP-376 in the Treatment of Chronic Bacterial Infections in Cystic Fibrosis Patients

... treatment of pulmonary infections due to Pseudomonas aeruginosa and other bacteria in patients with cystic fibrosis. MP-376 is Mpex's proprietary aerosol ... antibiotics to overcome or directly inhibit the molecular mechanisms in bacteria responsible for antibiotic resistance. Mpex's most advanced product ...

Iomai Announces Publication in The Lancet of Phase II Study Demonstrating Significant Efficacy of Travelers' Diarrhea Vaccine

... safety of the vaccine and the incidence of enterotoxigenic E. coli (ETEC) bacteria - the most common cause of travelers' diarrhea. No vaccine-related ... 55 million international travelers will visit countries where bacteria that cause travelers' diarrhea are endemic, particularly Africa, Asia and ...

Anpath Group, Inc. Announces Addition of MRSA and VRE Claims for Its EnviroTru(R) Disinfectant

... for more deaths in the U.S. each year than AIDS. Enterococci are bacteria that are normally present in the human intestines and in the urinary tract and are often found in the environment. These bacteria can sometimes cause infections. Vancomycin is an antibiotic that is often ...

Wyeth Receives Approvable Letter from FDA for TYGACIL for the Treatment of Patients with Community-Acquired Pneumonia

... Safety Information -- To reduce the development of drug-resistant bacteria and maintain the effectiveness of TYGACIL and other antibacterial ... infections proven or strongly suspected to be caused by susceptible bacteria -- Anaphylaxis/anaphylactoid reactions have been reported with nearly all ...

Steroids Provide No Survival Benefit for Children With Bacterial Meningitis

... in the subsets of children with meningitis caused by pneumococcal bacteria or by meningococcal bacteria. Meningitis is an inflammation of the ... and treatment with antibiotics. Several different varieties of bacteria may cause meningitis, although the patterns have changed with the ...

More Clinical Data Required to Support European Approval of CAP Indication for TYGACIL

... Safety Information -- To reduce the development of drug-resistant bacteria and maintain the effectiveness of TYGACIL and other antibacterial ... infections proven or strongly suspected to be caused by susceptible bacteria -- Anaphylaxis/anaphylactoid reactions have been reported with nearly all ...