Diagnosing Diabetes: Immediate HbA1c Results Improve Glycemic Control
...st antigens like insulin provides early markers of autoimmune disease activity. Measurement of these markers has been shown to be valuable in helping health-care providers diagnose and manage their diabetes patients. KRONUS, Inc., Boise, ID, offers a variety of ELISA and RIA kits for the quantitative determinat...Non-Invasive Diagnostic Tests for Celiac Disease
...D. Contributing Editor Celiac disease (CD) is an autoimmune inflammatory disease of the small intestine that i...erpetiformis, insulin-dependent diabetes mellitus, autoimmune thyroid disease, and chronic fatigue. Untreated CD is associated with multiple important short- and ...Micromet, Inc. to Present at the 3rd Annual C.E. Unterberg, Towbin Emerging Growth Conference
...ntibody-based products for cancer, inflammatoryand autoimmune diseases, today announced that Dr. Christian Itin,...ntibody-based products forcancer, inflammatory and autoimmune diseases. Two productcandidates are currently in clinical trials. MT103/MEDI-538, whichis the first ......se 3 clinical trialof Revimmune, to treat numerous autoimmune diseases with an initialindication targeting refractory relapsing-remitting MultipleSclerosis. Revimmune is based on pulsed, ultra-high dosing of awell-known chemotherapeutic agent under a risk management program.Additionally, through an investment s......se 3 clinical trialof Revimmune, to treat numerous autoimmune diseases with an initialindication targeting refractory relapsing-remitting MultipleSclerosis. Revimmune is based on pulsed, ultra-high dosing of awell-known chemotherapeutic agent under a risk management program.Additionally, through an investment s...Opexa Advances Monocyte Derived Islet Technology to Proof of Principle in stz-induced NOD/SCID Mice
...develops and commercializes cell therapies totreat autoimmune diseases such as multiple sclerosis, rheumatoidarthritis, and diabetes. The Company is focused on autologouscellular therapy applications of its proprietary T-cell and stemcell therapies. The Company's lead product, Tovaxin(TM), a T-celltherapy for m......ematosus (SLE), commonly called lupus, is achronic autoimmune disease that causes the body to attack its owntiss...rently approvedby the FDA for the treatment of any autoimmune disease. Conference Call Aspreva will host a conference call to discuss results onWednesday, June ......ntibody-based products for cancer, inflammatoryand autoimmune diseases, announced that a study published recentl...ntibody-based products forcancer, inflammatory and autoimmune diseases. Two productcandidates are currently in clinical trials. MT103/MEDI-538, whichis the first ......develops and commercializes cell therapies totreat autoimmune diseases such as MS, rheumatoid arthritis, anddiabetes. The Company is focused on autologous cellular therapyapplications of its proprietary T-cell and stem cell therapies. TheCompany's lead product, Tovaxin(TM), a T-cell therapy for multiplesclerosi......hritis, the most common form of arthritis, RA isan autoimmune disease where joints are inflamed, which may lead todamage of the joints' interior and the surrounding bone. The jointsmost commonly affected during the beginning of the disease are thesmaller joints of the fingers, feet and wrists. The elbows, knees......juvenile rheumatoid arthritis (JRA)- is a chronic, autoimmune disease, causing chronic pain, stiffnessand swelling of the joints, which may ultimately lead to jointdamage and deformities. The disease usually begins before the ageof 16 and may affect up to 1 child in every 1,000 in the UnitedStates. Despite curr...Pluristem's PLX Cells Demonstrate Potential to Treat Parkinson's Disease
...ment of numerous severe degenerative,malignant and autoimmune disorders. The Company's first plannedproduct, PLX-I, targets a $2 billion market and is intended toresolve the global shortfall of matched tissue for bone marrowtransplantation (BMT) by improving the engraftment of hematopoieticstem cells (HSCs) con......sts can reduceautoantibody levels and help control autoimmune diseaseactivity. LymphoStat-B was generated by HGS through a collaboration withCambridge Antibody Technology. It has received a "fast-trackproduct" designation from the FDA for its potential use in treatingSLE and has been selected for participation...... the expression of A3adenosine receptor in various autoimmune diseases. High expressionof this receptor is directly correlated with response ofinflammatory cells to this drug. Prof. Pnina Fishman, CEO of Can-Fite: "I am pleased with therapid progress in the CF502 development program and with thein-vitro and in...Cimzia Effective in Reducing Signs and Symptoms of Rheumatoid Arthritis
...thritis Rheumatoid arthritis (RA) is a progressive autoimmune disease whichcauses chronic inflammation of the joints. It is estimated that5 million people suffer from RA globally,[2] with 0.3% to 1% of thepopulation in industrialized countries suffering from RA.[3] Prevalence is not split evenly between gender......ased productsfor the targeted treatment of cancer, autoimmune and other seriousdiseases. We have developed a num... epratuzumab, to UCB, S.A. for thetreatment of all autoimmune disease indications worldwide. We haveretained the rights for epratuzumab in oncology indications fo......topenic Purpura ITP is characterized by increased autoimmune plateletdestruction and/or inadequate platelet production. Its cause iscurrently unknown. Some patients with ITP are asymptomatic or havemild bruising while others develop more serious bleeding that canbe life-threatening.(6) A normal blood platelet ......hese vaccine inducedresponses may help control the autoimmune processes that arethought to be the main cause of ...d to develop similar therapeuticvaccines for other autoimmune diseases such as rheumatoid arthritis(RA) and psoriasis." In MS, a specific subset of a patient's o...Opexa Presents Tovaxin Research at Federation of Clinical Immunology Societies Annual Meeting
...develops and commercializes cell therapies totreat autoimmune diseases such as multiple sclerosis, rheumatoidarthritis, and diabetes. The Company is focused on autologouscellular therapy applications of its proprietary T-cell and stemcell therapies. The Company's lead product, Tovaxin(TM), a T-celltherapy for m...Studies Show Efficacy and Safety of Alexion's Soliris in Broad Population of PNH Patients
... states, including hematologicdiseases, cancer and autoimmune disorders, and in May 2007,received a corporate leadership award from the NationalOrganization of Rare Disorders (NORD) for the development ofSoliris. Alexion applied for marketing authorization with theEuropean Medicines Evaluation Agency (EMEA) for......tis Rheumatoid arthritis is aprogressive, systemic autoimmune disease characterized by chronicinflammation of mu... expected tobe the company's emerging franchise in autoimmune diseases withrheumatoid arthritis as the first indication. Following the launchof MabThera® (rit...Immunomedics Reports Initial Clinical Results With Hpam4 For Pancreatic Cancer Therapy
...ased productsfor the targeted treatment of cancer, autoimmune and other seriousdiseases. We have developed a num... epratuzumab, to UCB, S.A. for thetreatment of all autoimmune disease indications worldwide. We haveretained the rights for epratuzumab in oncology indications fo...Soliris Effective in PNH Patients With History of Aplastic Anemia and Myelodysplastic Syndromes
... states,including hematologic diseases, cancer and autoimmune disorders,and in May 2007, received a corporate leadership award from theNational Organization of Rare Disorders (NORD) for the developmentof Soliris. Alexion applied for marketing authorization with theEuropean Medicines Evaluation Agency (EMEA) for......ased productsfor the targeted treatment of cancer, autoimmune and other seriousdiseases. We have developed a num... epratuzumab, to UCB, S.A. for thetreatment of all autoimmune disease indications worldwide. We haveretained the rights for epratuzumab in oncology indications fo...Promising Results with Epratuzumab and Chemotherapy in Children with Acute Lymphoblastic Leukemia
...ased productsfor the targeted treatment of cancer, autoimmune and other seriousdiseases. We have developed a num... epratuzumab, to UCB, S.A. for thetreatment of all autoimmune disease indications worldwide. We haveretained the rights for epratuzumab in oncology indications fo......rmerly referred toas TACI-Ig) for the treatment of autoimmune diseases and B-cellmalignancies. Atacicept contain...ay of clinical opportunities thatinclude bleeding, autoimmune diseases and cancer. ZymoGeneticsintends to commercialize these product candidates through internald......and active in other major therapeuticareas such as autoimmune diseases, inflammation, metabolism andcentral nervous system. In 2006 sales by the PharmaceuticalsDivision totalled 33.3 billion Swiss francs, and the DiagnosticsDivision posted sales of 8.7 billion Swiss francs. Roche employsroughly 75,000 worldwide......and active in other major therapeuticareas such as autoimmune diseases, inflammation, metabolism andcentral nervous system. In 2006 sales by the PharmaceuticalsDivision totalled 33.3 billion Swiss francs, and the DiagnosticsDivision posted sales of 8.7 billion Swiss francs. Roche employsroughly 75,000 worldwide......erol management,hypertension, organ transplant and autoimmune diseases. LifeCyclePharma's product candidates are proprietary and designed to improvethe quality of existing drugs by enhancing the release andabsorption of drugs in the human body. LifeCycle Pharma'sproprietary technology platform, MeltDose(R) tech......okine andchemoattractant systems in order to treat autoimmune diseases,inflammatory disorders and cancer. The chemokine system is acomplex network of chemokine molecules, or ligands, and receptorsthat regulates inflammation. Based on their proprietary drugdiscovery and drug development platform, ChemoCentryx ha......nderstanding of Crohn's disease as aninappropriate autoimmune response in the GI tract, we aredeveloping Alequel as an individualized oral treatment thatharnesses the patient's own immune system to alleviate symptoms,"said Gary C. Cupit, PharmD, President of Enzo Therapeutics. "ManyCrohn's patients are frustrat...PDL BioPharma Announces Long-Term Nuvion Data Presented at 2007 Digestive Disease Week
...y and development of antibodies totreat cancer and autoimmune diseases. For more information, pleasevisit <a target="_blank" href="http://www.pdl.com/">www.pdl.com . Forward-looking Statements The information in this press release should be consideredaccurate only as of the date of this press release.......and frequentbowel movements. This serious, chronic autoimmune disease affectsapproximately 700,000 Americans. For more information on UC, visit<a target="_blank" href="http://www.managinguc.com/">http://www.managinguc.com . Important Safety Information LIALDA tablets are indicated for the induction of...... link betweendiet involving probiotics and certain autoimmune diseases. In the second study, mice were fed Bifantis and then exposed toSalmonella, a common bacteria associated with a form of foodpoisoning. Animals that received Bifantis showed dramaticallyincreased numbers of certain immune cells that control ...Innovative Cancer Drug MabThera Again Shown To Improve Survival Rates In Patients With Lymphoma
...and active in other major therapeutic areas suchas autoimmune diseases, inflammation, metabolism and centralnervous system. In 2006 sales by the Pharmaceuticals Divisiontotalled 33.3 billion Swiss francs, and the Diagnostics Divisionposted sales of 8.7 billion Swiss francs. Roche employs roughly75,000 worldwide......hemorrhagic colitis, development orexacerbation of autoimmune disorders including thyroiditis, RA,systemic lupus erythematosus, psoriasis, pulmonary disorders(dyspnea, pulmonary infiltrates, pneumonitis and pneumonia, someresulting in patient deaths), urticaria, angioedema,bronchoconstriction, anaphylaxis, reti...BioLineRx Presents Phase I Clinical Data of BL-1020 at Upcoming Clinical Conferences
... and CNS, cardiovascular, metabolic, infectiousand autoimmune diseases. BioLineRx advances projects from early stage discovery and leadgeneration to advanced clinical trials, regulatory approval andmarketing. Partnering with researchers, universities and biotechcompanies to further the commercialization of pro...Ulcerative Colitis (UC) Sufferers Find UC Quite Disruptive to Many Aspects of Daily Life
...r who helped design thesurveys. UC is a chronic autoimmune disease that causes inflammation inthe intestine a...ody diarrhea, fatigue andweight loss. This chronic autoimmune disease is typically firstdiagnosed in people between the ages of 15 to 30 and is estimatedto affect......eliac Disease Celiac Disease is a T-cell mediated autoimmune disease thatoccurs in genetically susceptible indi...lization of disease modifyingtherapeutics to treat autoimmune and inflammatory diseases basedupon the regulation of tight junctions. Alba's lead compound,AT-1001,......ctions of LX211 to prevent andreverse experimental autoimmune uveoretinitis (EAU) in rats.Cunningham commented, “We observed that in this animal model,LX211 could both prevent the onset of disease as well as reverseEAU at doses as low as 10mg/kg. These preclinical results clearlysupport our view that LX21......ctions of LX211 to prevent and reverseexperimental autoimmune uveoretinitis (EAU) in rats. Cunninghamcommented, ...nism demonstrated toprovide efficacy in a range of autoimmune diseases such asnoninfectious uveitis - and also appears to be well tolerated. Inaddition to uveitis...Data to be presented at AAN Meeting -Study results of drug candidate for MS
... in an established animal model ofMS [experimental autoimmune encephalomyelitis (EAE) in rats],researchers found...ated effects of FTY720(Fingolimod) in experimental autoimmune encephalomyelitis (EAE) inDA rats, an animal model of multiple sclerosis. Conclusion/Relevance: The...Abbott's Investigational Treatment ABT-874 Shows Positive Results in Phase II Psoriasis Study
...olating, painful disease." Psoriasis is a chronic autoimmune disease affecting 125 millionpeople worldwide. About 25 percent have moderate to severe disease.The condition speeds the growth cycle of skin cells and results inthick, scaly areas of skin. The most common form of psoriasisappears as red, raised area......additionalstudies with CD83 in transplantation and autoimmune models, whichwill provide important information as...d to treat transplantationrejection and variety of autoimmune disorders. Importantly, datafrom animal models demonstrate that soluble CD83 exerts its effectswitho...Revolutionary Immunologic Data Explains Function of Diamyd Diabetes Vaccine
...ally, but thatthe clinical effect of arresting the autoimmune attack thatdestroys beta cells close to disease on... according to theprevailing theory of how to treat autoimmune disease. This meansthat the successful clinical effect of Diamyd® administrationis starting to b...Xanthus Presents Novel Approach for Autoimmune Disease Reversal with Symadex
...eting in Boston, MA. Using a model of experimental autoimmune encephalomyelitis (EAE)that is designed to represe...ppressant. "Symadex' ability to reverse chronic autoimmune disease in thisanimal model is notable. The study results suggest this activitymay result from inhib...Pluristem to Present Two Scientific Posters at the International Society for Cellular Therapy
...ment of numerous severe degenerative,malignant and autoimmune disorders. The Company's first plannedproduct, PLX-I, targets a $2 billion market and is intended toresolve the global shortfall of matched tissue for bone marrowtransplantation (BMT) by improving the engraftment of hematopoieticstem cells (HSCs) con...MabThera Significantly Increases Survival of Lymphoma Patients Regardless of Chemotherapy Regimen
...and active in other major therapeutic areas suchas autoimmune diseases, inflammation, metabolism and centralnervous system. In 2006 sales by the Pharmaceuticals Divisiontotalled 33.3 billion Swiss francs, and the Diagnostics Divisionposted sales of 8.7 billion Swiss francs. Roche employs roughly75,000 worldwide......ough 48weeks. About MS and RRMS MS is a chronic autoimmune disease of the central nervous system(CNS) in whic...those with hematologicmalignancies or with certain autoimmune diseases such as systemiclupus erythematosus (SLE), an indication for which Rituxan has notbeen appr......rough 48weeks. About MS and RRMS MS is a chronic autoimmune disease of the central nervous system(CNS) in whic...those with hematologicmalignancies or with certain autoimmune diseases such as systemiclupus erythematosus (SLE), an indication for which Rituxan has notbeen appr......and active in other major therapeutic areas suchas autoimmune diseases, inflammation, metabolism and centralnervous system. In 2006 sales by the Pharmaceuticals Divisiontotalled 33.3 billion Swiss francs, and the Diagnostics Divisionposted sales of 8.7 billion Swiss francs. Roche employs roughly75,000 worldwide......the publication of data suggestingthat established autoimmune disease can be reversed or stabilizedby the transp...ative conditioning offers anovel strategy to treat autoimmune diseases such as lupus withdecreased morbidity," said Ramkumar Mandalam, Ph.D., Vice Presidentof Pha...Micromet Achieves Milestone in BiTE Research Collaboration with MedImmune
...ntibody-based products forcancer, inflammatory and autoimmune diseases. Two productcandidates are currently in clinical trials. MT103/MEDI-538, whichis the first product candidate based on Micromet's novel BiTE(R)product development platform, is being evaluated in a phase 1clinical trial for the treatment of pa......uniquemechanisms of action for oncology, viral and autoimmune disorders.VioQuest has two targeted therapeutics in Phase I/IIa clinictrials: VQD-002 which inhibits activation of Akt that is seen atabnormally high levels in breast, ovarian, colorectal, pancreatic,and hematologic tumors; and Lenocta (TM), an inhib......r DNA-binding protein, in the pathologyof systemic autoimmune diseases such as systemic lupuserythematosus (SLE or lupus) and rheumatoid arthritis. Data to bepublished in the May 2007 issue of Nature Immunology show thatHMGB1 is an essential component of DNA-immune complexes thatstimulate immune cells to produc...Critical Therapeutics Announces the Publication of New Preclincial HMGB1 Data in Nature Immunology
...urn can contribute to the inflammatorypathology of autoimmune disease. The work adds to the growing bodyof liter... About Lupus(2) Lupus is a widespread and chronic autoimmune disease that causesthe immune system to attack the body's tissue and organs, includingthe joints, ki...MedImmune and Micromet Publish Data on Novel Anti-Cancer BiTE Molecule
...ntibody-based products forcancer, inflammatory and autoimmune diseases. Two productcandidates are currently in clinical trials. MT103/MEDI-538, whichis the first product candidate based on Micromet's proprietaryBiTE(R) product development platform, is being evaluated in a phase1 clinical trial for the treatment...Micromet and MedImmune Present Data From Preclinical Study of New BiTE Molecule Targeting CEA
...ntibody-based products forcancer, inflammatory and autoimmune diseases. Two productcandidates are currently in clinical trials. MT103/MEDI-538, whichis the first product candidate based on Micromet's novel BiTE(R)product development platform, is being evaluated in a phase 1clinical trial for the treatment of pa......ug candidates to treat cancer,infectious diseases, autoimmune diseases, allergy/asthma, and foruse as vaccine adjuvants. Idera's proprietary drug candidates aredesigned to modulate TLRs, the body's first line of immune defense.Idera's pioneering DNA chemistry expertise enables it to identifydrug candidates for ......reforemay play a role in treatment of lymphomas or autoimmune disease.Other tyrosine kinases are important in cell signaling and havebeen targets for other drugs such as imatanib mesylate(Gleevec(R)), which is approved for treatment of certain leukemias.New drug or biological candidates targeting B-cells, inclu...