Antimicrobial in Medical Technology

Alcon Commences Phase 2 Clinical Trial of NovaBay's NVC-422 for Viral Conjunctivitis

... are novel, proprietary, synthetic N-chlorinated antimicrobial molecules specifically developed by NovaBay to ... stability of naturally occurring N-chlorinated antimicrobial molecules. These highly differentiated compounds ... candidates that are bioequivalent to the active antimicrobial molecules generated within white blood cells to ...

NovaBay(R) Pharmaceuticals Enters into Agreement to Broaden Intellectual Property Estate and Expand Clinical Opportunities for Its Aganocide(R) Compounds

... on the use of N-chlorotaurine (NCT), a natural antimicrobial produced by the body's white blood cells. ... are novel, proprietary, synthetic N-chlorinated antimicrobial molecules specifically designed by NovaBay to ... stability of naturally occurring N-chlorinated antimicrobial molecules. These highly differentiated compounds ...

Pew Commission Says Industrial Scale Farm Animal Production Poses 'Unacceptable' Risks to Public Health, Environment

... the increased opportunities for the generation of antimicrobial resistant bacteria (due to imprudent antimicrobial use) or new strains of viruses. Stresses ... food animal production to reduce the risk of antimicrobial resistance to medically important antibiotics ...

DermaGen AB Receives Over 1 Million Euros From a New Share Issue

... a clinical trial with DPK-060. This is a novel antimicrobial treatment for AD, and our lead antimicrobial candidate for topical use, it will be tested in a ... 2004, is a world leader in research on endogenous antimicrobial peptides. A specialty pharmaceutical ...

MacroChem Announces Presentation of Pexiganan Phase 3 Study Results for Topical Treatment of Diabetic Foot Infection

... of a poster entitled "Topical versus Systemic antimicrobial Therapy for Treating Infected Diabetic Foot ... the efficacy of an investigational topical antimicrobial peptide preparation, pexiganan acetate cream, ... first to demonstrate the efficacy of a topical antimicrobial in treating diabetic foot infection in ...

FreshFx Recognized for use in the Scalder as a Solution to the 'Yield/Pathogen Reduction Dilemma'

... SHREVEPORT, La., Nov. 6 /PRNewswire/ -- FreshFx antimicrobial Solution, which is used to reduce pathogens ... nearly 2 billion birds. "FreshFx can maintain antimicrobial activity even in the presence of the accumulated ... products. For more about SteriFx Inc. or FreshFx antimicrobial solutions, please visit http://www.sterifx.com ...

Cutanea Announces Promising Phase II Results in Rosacea with Omiganan

... for dermatological uses to a novel, cationic, antimicrobial peptide, whose active component is omiganan ... evidence of systemic absorption. While cationic antimicrobial peptides, such as Omiganan, are well known for their antimicrobial properties, recent research has shown that they ...

D1 Sports Training Facilities Adopt TurfAide(TM) Antimicrobial to New Synthetic Turf Fields from AstroTurf(R)

... with the addition of the high-tech TurfAide(TM) antimicrobial from SportCoatings(TM). D1 Sport Facilities are ... TurfAide is a unique treatment that provides antimicrobial protection to synthetic turf systems. "D1 is ... president of GSV. TurfAide is part of the Sports antimicrobial System(R) (SAS), a powerful family of treatments ...

Oritavancin Demonstrates Superior In Vitro Activity to Vancomycin and Metronidazole Against C. Difficile Bacteria

... the 47th Annual Interscience Conference on antimicrobial Agents and Chemotherapy (ICAAC) taking place in ... that C. difficile spores refractory to current antimicrobial therapies persist, causing recurrent infections. ... to a greater extent than existing therapeutic antimicrobial agents. In addition, there was a marked ...

CDC Analysis Finds Unique Social and Behavior Intervention Helps Reduce MRSA Rates Up to 62% in Study Hospitals

... "Reports of successful multicenter interventions to reduce endemic antimicrobial resistance problems among U.S. hospitals are extremely rare," says John A. ... available. It shows that hospitals can make an important difference in antimicrobial resistance even at a time when the availability of new antibiotics has ...

Lytix Presents LTX-109 Anti-Microbial Data at ICAAC

... company Lytix Biopharma has announced results of studies on its lead antimicrobial candidate LTX-109. Presented at ICAAC in Washington, DC, the studies ... in during the second half of 2009." LTX-109 is a novel synthetic antimicrobial pepitidomimetic (SAMP) drug with a rapid bactericidal mode of action that ...

10 Million Square Feet of Turf Set to be Treated in 2008 in Response to MRSA Outbreaks Nationwide

... square feet of synthetic turf will be treated with its industry-leading antimicrobial coating, TurfAide(TM), in 2008 -- up from 1.5 million square feet in ... "More synthetic turf systems will be treated with TurfAide than all other antimicrobial products combined in 2008; because it's a proven and powerful technology ...

National Wrestling Coaches Association Teams Up With CSG/SportsCoatings(TM)

... and fungi to the wrestling community. Nationally renowned for its Sports antimicrobial System (R) that inhibits and controls the growth of microbial contaminants ... has gained prominence in the athletic community through its unique Sports antimicrobial System(R). Comprised of several different products and treatments, the ...

Cethromycin Achieves All Endpoints in Second Pivotal Phase III Trial for Treatment of Pneumonia

... interests are in the study of the epidemiology and the mechanisms of antimicrobial resistance in community and hospital pathogens. Other research interests ... for their Canadian population-based surveillance programs for the study of antimicrobial resistance and infectious diseases. A recognized authority in microbiology ...

MacroChem Acquires Rights to Pexiganan, a Novel Topical Anti-Infective for Treatment of Diabetic Foot Infections, From Genaera

... Foot Infection, commented, "I think there is a clear need for a topical antimicrobial compound for treatment of mild diabetic foot infections. Why expose the ... its ability to disrupt the integrity of bacterial cell membranes. It has antimicrobial activity against Gram positive (methycillin resistant staphylococcus ...

Molnlycke Drives 'Home' the Fight Against Staph and Other MRSA Infections

... of the products used by consumers do not contain pharmaceutical-quality, antimicrobial agents with residual activity like chlorhexidine gluconate (CHG) found ... as Hibiclens(R), according to Twomey. Residual activity works when the antimicrobial bonds with the skin to prevent recontamination. For hand cleansers, this ...

Replidyne's Investigational Antibacterial Agent REP3123 Prevents Toxin Production in Clostridium difficile

... be Presented at the 47th Annual Interscience Conference on antimicrobial Agents and Chemotherapy LOUISVILLE, Colo., Sept. 19 ... Clostridium difficile" at the 47th Annual Interscience Conference on antimicrobial Agents and Chemotherapy held at the McCormick Place conference center in ...

Replidyne's Investigational Antibacterial Agent REP3123 Prevents Sporulation in Clostridium difficile

... be Presented at the 47th Annual Interscience Conference on antimicrobial Agents and Chemotherapy LOUISVILLE, Colo., Sept. 19 ... Clostridium difficile" at the 47th Annual Interscience Conference on antimicrobial Agents and Chemotherapy held at the McCormick Place conference center in ...

Keeping the Data Center Clean: ATEN Launches Industry-First KVM Switches with Antimicrobial Nanocoating to Protect Products from Bacteria Surviving on Surfaces

... today unveiled the first LCD KVM switches to feature product-protected antimicrobial nanocoating. The average desk harbors 400 times more bacteria than the ... ATEN products will be the first KVM switches to offer the protective antimicrobial nanocoating: -- KL9108M/KL9116M Hideaway(TM) LCD Console Over the NET -- ...

Advanced Life Sciences to Present Data on Selected Cethromycin Therapeutic Studies at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy

... Against Strains of Haemophilus influenzae -- Poster E1634: antimicrobial Activity of Cethromycin, a Novel Ketolide, Tested against a Diverse ... for Microbiology (ASM) is hosting the 47th Interscience Conference on antimicrobial Agents and Chemotherapy (ICAAC), which will be held in Chicago, Illinois, ...

Teeth and Gums Also Benefit from the Healing Power of Aloe Vera

... to ensure that it meets the standards of organized dentistry, too." Editor's Note: A copy of the study, "Comparative evaluation of the antimicrobial efficacy of aloe vera tooth gel and two popular commercial toothpastes," is available. Call 312.440.4346 or e-mail media@agd.org " target="_new"> ...

Schering-Plough Expands Vicriviroc Phase II Study in Treatment-Naive Patients With HIV

... 2008, DOI:10.1016/S0140-6736(08)60423-7. 8 Dunkle LM, Greaves WL, et al. Long-Term Safety of Vicriviroc. 48th Annual Interscience Conference on antimicrobial Agents and Chemotherapy (ICAAC)/Infectious Diseases Society of America (IDSA) 46th Annual Meeting; Oct. 25-28, 2008; Washington, D.C., USA; No. ...

Calixa Therapeutics Announces Initiation of Phase 2 Clinical Trial of Its Antibiotic, CXA-101, in Patients with Complicated Urinary Tract Infections

... chief medical officer of Calixa. "We are going to present comprehensive preclinical and Phase 1 data at the 49th Interscience Conference on antimicrobial Agents and Chemotherapy in September and other medical conferences. This Phase 2 study will generate important information on the safety and ...

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... during and after treatment with SIMPONI. If a patient develops a serious infection or sepsis, SIMPONI therapy should be discontinued and appropriate antimicrobial therapy should be initiated. Patients should be advised of and avoid exposure to potential risk factors for infection as appropriate. For patients ...

Cepheid Receives Grant to Develop Ten-Color Real-Time PCR Detection Technology for Use in the GeneXpert(R) System

... applications by increasing the total number of diagnostic results per sample. The technology will also enable the development of new, comprehensive antimicrobial resistance and oncology tests. "The workup of many infectious conditions requires considerable guesswork on the part of clinicians, who ...

TYRX Presents Early Clinical Results from AIGISRX(TM) Antibacterial Envelope Retrospective Registry

... commercializes implantable combination drug/device products, including the AIGIS RX (TM) Anti-Bacterial Envelope. AIGIS contains the antimicrobial agents, rifampin and minocycline, which have been shown to reduce infection by organisms representing a majority of the infections reported in ...

Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)

... with CIMZIA should be closely monitored, undergo a prompt and complete diagnostic workup appropriate for immunocompromised patients, and appropriate antimicrobial therapy should be initiated. Appropriate empiric antifungal therapy should also be considered while a diagnostic workup is performed for patients who ...

Clinician Reports Fast Healing of Intractable Wounds Using MEDIHONEY(R)

... with VLUs that had not healed with other advanced wound care modalities - including the gold standard multi-layered compression, as well as silver antimicrobial dressings, hyperbaric oxygen therapy, and antibiotic therapy - for at least 4 months' duration. The study was designed to measure the percentage of ...

DSM Obtains Exclusive World-Wide License for Innovative Drug Delivery Technology

... library of synthesis methods, formulation and processing techniques. DSM's current biomedical portfolio also includes ComfortCoat(TM) hydrophilic and antimicrobial coating technology for catheters, guidewires and stent delivery systems and Dyneema Purity(R), a high performance polyethylene fiber technology, ...

NovaBay Pharmaceuticals Announces Lead Anti-infective Product Candidate, NVC-422, Shown to be Effective in Treating Topical Fungal Infection

... biopharmaceutical company developing first-in-class, novel, synthetic anti-infective product candidates that are bioequivalent to the active antimicrobial molecules generated within white blood cells to treat and prevent a wide range of infections without developing resistance. NovaBay has entered into ...

MEDIHONEY(TM) Dressings Shown to Help Improve Outcomes of Non-Healing Venous Leg Ulcers in Recent Case Series

... leg ulcers. These wounds had previously failed to heal while being managed with such therapeutic modalities as multi-layered compression, silver antimicrobial dressings, antibiotic therapy, and hyperbaric oxygen. Six of the wounds completely healed within 4 weeks, and all eleven wounds healed within 6 ...

Nanoemulsion Kills Highly Resistant Bacteria Found in Patients With Cystic Fibrosis

... failure in patients with cystic fibrosis, according to the study authors. Results of the in vitro study are published in the January issue of antimicrobial Agents and Chemotherapy. "Respiratory tract infections are the primary cause of death in persons with cystic fibrosis, and there are simply no ...

Cadence Pharmaceuticals Reports Third Quarter 2008 Financial Results and Provides Clinical Development Programs Update

... candidates -- Acetavance(TM), an intravenous formulation of acetaminophen for the treatment of acute pain and fever, and Omigard(TM), a topical antimicrobial gel for the prevention of catheter-related infections. "During the third quarter of 2008, and as previously announced, the Food and Drug ...

New Data Show In Vitro Potency of Doripenem Against Resistant Bacteria

... other organs of the body and includes common bacteria strains such as E. coli. These new data were presented at the 48th Interscience Conference on antimicrobial Agents and Chemotherapy (ICAAC) / Infectious Diseases Society of America (IDSA) 46th annual meeting in Washington, D.C. In the study, the incidence ...

Rib-X Pharmaceuticals Reports Positive Phase 2 Study Results for Next Generation Oxazolidinone at 2008 ICAAC/IDSA Joint Meeting

... for the treatment of uncomplicated skin and skin structure infections (uSSSI). These results were announced at the 48th Interscience Conference on antimicrobial Agents and Chemotherapy (ICAAC)/Infectious Diseases Society of America (IDSA) 46th annual meeting (2008 ICAAC/IDSA Joint Meeting) held October 25 - ...

Pivotal Phase III Data Confirm the Efficacy and Safety of Arpida's Intravenous Iclaprim in Treating Patients With Complicated Skin and Skin Structure Infections

... -- Arpida (SWX: ARPN) today presented the combined results from two pivotal Phase III clinical trials at the 48th Interscience Conference on antimicrobial Agents and Chemotherapy (ICAAC)/Infectious Diseases Society of America (IDSA) 46th annual meeting in Washington, DC. In these studies, intravenous ...

Data Reported at ICAAC Indicates Selzentry(TM) Phase III Treatment-Naive Trial Shows Increased Efficacy When Used With Enhanced Trofile(TM) Assay

... by use of the enhanced version of Monogram's Trofile(TM) Assay. The data were reported this week at the 48th Annual Interscience Conference on antimicrobial Agents and Chemotherapy (ICAAC) / 46th Annual Meeting of the Infectious Diseases Society of America (IDSA) in Washington DC. Pfizer's HIV ...

Analysis of Long-Term Vicriviroc Data Provides Evidence of Sustained Viral Suppression, Increased CD4 Cell Counts and Tolerability in Treatment-Experienced HIV-Infected Patients

... Oct. 20-21, 2006; Boston, MA, USA; No. 8. (2) Dunkle LM, Greaves WL, et al. Long-Term Safety of Vicriviroc. 48th Annual Interscience Conference on antimicrobial Agents and Chemotherapy (ICAAC)/Infectious Diseases Society of America (IDSA) 46 Annual Meeting; Oct. 25-28, 2008; Washington, D.C., USA; No. ...

Sequoia Pharmaceuticals Presents In Vitro and First-in-Human Data Supporting Further Development of SPI-256, a Novel Investigational Protease Inhibitor

... in humans and is amenable to boosting by pharmacokinetic enhancers (PKEs). The data were presented at the 48th annual Interscience Conference on antimicrobial Agents and Chemotherapy (ICAAC)/46th annual Infectious Diseases Society of America (IDSA) joint meeting held in Washington, D.C. "Two ongoing ...

Long-Term Study Evaluates Boosted PREZISTA(R) Vs. Lopinavir/Ritonavir as Part of HIV Combination Therapy in Treatment-Naive Adults

... and tenofovir disoproxil fumarate. Results from the study, known as ARTEMIS, were presented today at the 48th Interscience Conference on antimicrobial Agents and Chemotherapy (ICAAC) in Washington, DC. ARTEMIS is a 192-week study comparing the efficacy and safety of the protease inhibitors (PIs) ...