CNS Response, Inc. Provides Review of Poster Session Delivered at the American Psychiatric Association 161st Annual Meeting
... days for the
patients decreased dramatically.
anorexia nervosa is a potentially fatal
illness with ... lives of
those with severe mental conditions. One
anorexia nervosa patient had
previously received five ... have shown consistent success in treatment of
anorexia nervosa. For
the 24 months following, the patient ...
CHMP Recommends Approval in the European Union (EU) for New Options for Patients With Certain Primary Brain Tumors
... alopecia 69%, 55%; fatigue 54%, 61%; nausea 36%, 49%; vomiting 20%, 29%;
anorexia 19%, 27%; headache 19%, 23%; constipation 18%, 22%; with the following ... respectively, were fatigue 7%, 9% nausea; 1%, 1%; vomiting <1%, 2%;
anorexia 1%, 1%; headache 2%, 4%; constipation 1%, 0%; convulsions 3%, 3%; ...
CuraGen Updates CR011-vcMMAE Data at ASCO
... events consisting of rash, alopecia, and pruritus were the most common toxicities in this study. Other adverse events included fatigue, diarrhea,
anorexia and nausea. Grade 3 or 4 neutropenia was observed in 5 patients. The absence of rash in the first cycle of treatment predicted a worse PFS. ...
Bayer Announces New Data on Novel Anti-cancer Compound BAY 73-4506
... in evaluable patients. The most common drug-related adverse events were hand-foot skin reaction (HFSR), fatigue, hoarseness, mucositis, diarrhea,
anorexia and hypertension. Data presented are based on 38 patients with actively progressing CRC enrolled in a Phase I study. Patients were treated with BAY ...
Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types
... eye edema (33% each); diarrhea, vomiting, rash, lacrimation increased, and anemia (25% each); face edema, pyrexia, exertional dyspnea, rhinitis, and
anorexia (17% each).
The majority of patients who received Gleevec in the GIST study experienced adverse reactions at some time. Most adverse reactions ...
Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen
... (33 percent), insomnia (30 percent), alopecia (28 percent), neutropenia (27 percent), nausea/vomiting (25 percent), rigors (25 percent),
anorexia (24 percent), injection site reaction (23 percent), arthralgia (22 percent), depression (20 percent), pruritus (19 percent) and dermatitis (16 ...
Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C
... (33 percent), insomnia (30 percent), alopecia (28 percent), neutropenia (27 percent), nausea/vomiting (25 percent), rigors (25 percent),
anorexia (24 percent), injection site reaction (23 percent), arthralgia (22 percent), depression (20 percent), pruritus (19 percent) and dermatitis (16 ...
Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports
... (46%), fatigue (39%), anemia (33%), pyrexia (32%), vomiting (32%), constipation (31%), dyspnea (27%), diarrhea (24%), weakness (24%), myalgia (23%),
anorexia (22%), cough (22%), arthralgia (21%), lower-limb edema (21%), malignant neoplasm aggravated (20%), headache (19%), dizziness (excluding vertigo) ...
Study Finds DOXIL(R) Combination Therapy Delays Disease Progression for Patients With Metastatic Breast Cancer
... asthenia (40% vs 51%), fever (21% vs 31%), nausea (46% vs
63%), stomatitis (41% vs 15%), vomiting (33% vs 44%), diarrhea (21% vs
35%),
anorexia (20% vs 22%), dyspnea (15% vs 23%), HFS (51% vs 1%), and
rash (29% vs 12%)
- In addition, 19% vs 52.3% reported alopecia (all ...
Continued Overall Survival Advantage Reported From Pivotal Trial of VELCADE(R) (Bortezomib) for Injection Based Therapy in Patients With Previously Untreated Multiple Myeloma
... vs 16%), neuralgia (36% vs 1%), leukopenia (33% vs 30%), vomiting (33% vs 16%), pyrexia (29% vs 19%), fatigue (29% vs 26%), lymphopenia (24% vs 17%),
anorexia (23% vs 10%), asthenia (21% vs 18%), cough (21% vs 13%), insomnia (20% vs 13%), edema peripheral (20% vs 10%), rash (19% vs 7%), back pain (17% vs ...
Prolonged Progression-Free Survival Demonstrated by VELCADE(R) (Bortezomib) for Injection Based Induction Regimens in Transplant-Eligible Previously Untreated Multiple Myeloma Patients
... vs 16%), neuralgia (36% vs 1%),
leukopenia (33% vs 30%), vomiting (33% vs 16%), pyrexia (29% vs 19%), fatigue
(29% vs 26%), lymphopenia (24% vs 17%),
anorexia (23% vs 10%), asthenia (21%
vs 18%), cough (21% vs 13%), insomnia (20% vs 13%), edema peripheral (20% vs
10%), rash (19% vs 7%), back pain (17% vs ...
Novel VELCADE(R) (Bortezomib) for Injection Based Four-Drug Combination Was Well Tolerated In Previously Untreated Multiple Myeloma Patients
... vs 16%), neuralgia (36% vs 1%),
leukopenia (33% vs 30%), vomiting (33% vs 16%), pyrexia (29% vs 19%), fatigue
(29% vs 26%), lymphopenia (24% vs 17%),
anorexia (23% vs 10%), asthenia (21%
vs 18%), cough (21% vs 13%), insomnia (20% vs 13%), edema peripheral (20% vs
10%), rash (19% vs 7%), back pain (17% vs ...
More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies
... (46%), fatigue (39%), anemia (33%), pyrexia (32%), vomiting (32%), constipation (31%), dyspnea (27%), diarrhea (24%), weakness (24%), myalgia (23%),
anorexia (22%), cough (22%), arthralgia (21%), lower-limb edema (21%), malignant neoplasm aggravated (20%), headache (19%), dizziness (excluding vertigo) ...
New Study Shows that PEGASYS(R) Regimen Provides Higher Sustained Virological Response Rates for Hepatitis C Patients
... (33 percent), insomnia (30
percent), alopecia (28 percent), neutropenia (27 percent), nausea/vomiting
(25 percent), rigors (25 percent),
anorexia (24 percent), injection site
reaction (23 percent), arthralgia (22 percent), depression (20 percent),
pruritus (19 percent) and dermatitis (16 ...
Early Data Show Potential for Imatinib Mesylate Tablets to Treat Life-Threatening Form of Pulmonary Artery Disease
... eye edema (33% each); diarrhea, vomiting, rash, lacrimation
increased and anemia (25% each); face edema, pyrexia, exertional dyspnea,
rhinitis, and
anorexia (17% each).
The majority of patients who received Gleevec in the GIST study
experienced adverse reactions at some time. Most adverse reactions ...
New England Journal of Medicine Publishes Phase III Results of VELCADE(R) (Bortezomib) for Injection in Previously Untreated Multiple Myeloma Patients
... vs 16%), neuralgia (36% vs
1%), leukopenia (33% vs 30%), vomiting (33% vs 16%), pyrexia (29% vs 19%),
fatigue (29% vs 26%), lymphopenia (24% vs 17%),
anorexia (23% vs 10%),
asthenia (21% vs 18%), cough (21% vs 13%), insomnia (20% vs 13%), edema
peripheral (20% vs 10%), rash (19% vs 7%), back pain (17% vs ...
ADVENTRX Presents CoFactor Data at the 2008 Annual Meeting of the American Society of Clinical Oncology (ASCO)
... in this study were expected and included
the following, which reflects all grades: asthenia (52%), nausea (33%),
diarrhea (29%), vomiting (26%),
anorexia (23%), dyspnea (23%), and
neutropenia (23%). Five patients reported 12 serious adverse events
(pneumonia, abdominal pain, diarrhea (2), general ...
Video: Major Independent Trial Demonstrates Significant Anticancer Benefit of Zometa(R) in Women With Early-Stage Breast Cancer
... (46%), fatigue (39%),
anemia (33%), pyrexia (32%), vomiting (32%), constipation (31%), dyspnea
(27%), diarrhea (24%), weakness (24%), myalgia (23%),
anorexia (22%), cough
(22%), arthralgia (21%), lower-limb edema (21%), malignant neoplasm
aggravated (20%), headache (19%), dizziness (excluding vertigo) ...
New Data Show TORISEL Improves Progression-Free Survival for Patients With Relapsed/Refractory Mantle Cell Lymphoma
... than or equal to 30%) adverse
reactions observed with TORISEL are: rash (47%), asthenia (51%), mucositis
(41%), nausea (37%), edema (35%), and
anorexia (32%). The most common
laboratory abnormalities (incidence greater than or equal to 30%) are
anemia (94%), hyperglycemia (89%), hyperlipemia (87%), ...
New Analyses Presented at ASCO Reaffirmed Efficacy and Safety of TORISEL in Patients With Advanced Kidney Cancer
... than or equal to 30%) adverse
reactions observed with TORISEL are: rash (47%), asthenia (51%), mucositis
(41%), nausea (37%), edema (35%), and
anorexia (32%). The most common
laboratory abnormalities (incidence greater than or equal to 30%) are
anemia (94%), hyperglycemia (89%), hyperlipemia (87%), ...
Wyeth Initiates INTORACT -- A New Clinical Trial to Examine TORISEL Plus Avastin for First-Line Treatment of Advanced Kidney Cancer
... than or equal to 30%) adverse
reactions observed with TORISEL are: rash (47%), asthenia (51%), mucositis
(41%), nausea (37%), edema (35%), and
anorexia (32%). The most common
laboratory abnormalities (incidence greater than or equal to 30%) are
anemia (94%), hyperglycemia (89%), hyperlipemia (87%), ...
PEGASYS(R)/COPEGUS(R) Show Benefit in Hard-to-Treat Latino Population with Hepatitis C
... (41%), myalgia (40%),
irritability/anxiety/nervousness (33%), insomnia (30%), alopecia (28%),
neutropenia (27%), nausea/vomiting (25%), rigors (25%),
anorexia (24%),
injection site reaction (23%), arthralgia (22%), depression (20%), pruritus
(19%) and dermatitis (16%). Serious adverse events in hepatitis C ...
Roche responds to announcement of 'IDEAL' hepatitis C trial results
... (41%), myalgia (40%),
irritability/anxiety/nervousness (33%), insomnia (30%), alopecia (28%),
neutropenia (27%), nausea/vomiting (25%), rigors (25%),
anorexia (24%),
injection site reaction (23%), arthralgia (22%), depression (20%), pruritus
(19%) and dermatitis (16%).
Serious adverse events in hepatitis ...
Twelve DOXIL(R) Clinical Studies to be Presented at American Society of Hematology Annual Meeting
... (64%), nausea (55%), diarrhea
(52%), constipation (41%), peripheral neuropathy (39%), thrombocytopenia
(36%), appetite decrease, including reports of
anorexia (36%), pyrexia
(34%), vomiting (33%) and anemia (29%). Twenty percent of patients reported
at least one episode of grade 4 toxicity; the most common ...
Wyeth's TORISEL Receives European Commission Approval for the Treatment of Advanced Kidney Cancer
... than or equal to 30%) adverse
reactions observed with TORISEL are: rash (47%), asthenia (51%), mucositis
(41%), nausea (37%), edema (35%), and
anorexia (32%). The most common
laboratory abnormalities (incidence greater than or equal to 30%) are
anemia (94%), hyperglycemia (89%), hyperlipemia (87%), ...
New Data to Support VELCADE(R) (Bortezomib) For Injection Based Therapies as Setting New Standards in The Care of Newly Diagnosed Patients With Multiple Myeloma
... (64%), nausea (55%), diarrhea
(52%), constipation (41%), peripheral neuropathy (39%), thrombocytopenia
(36%), appetite decrease, including reports of
anorexia (36%), pyrexia
(34%), vomiting (33%) and anemia (29%). Twenty percent of patients reported
at least one episode of grade 4 toxicity; the most common ...
Treatment with PEGASYS(R)/COPEGUS(TM) Provides Hope for Hepatitis C Patients Whose Infection Did Not Initially Respond to Peg-Intron(R)/Ribavirin
... (41%), myalgia (40%),
irritability/anxiety/nervousness (33%), insomnia (30%), alopecia (28%),
neutropenia (27%), nausea/vomiting (25%), rigors (25%),
anorexia (24%),
injection site reaction (23%), arthralgia (22%), depression (20%), pruritus
(19%) and dermatitis (16%). Serious adverse events in hepatitis C ...
Roche's Investigational Polymerase Inhibitor, Combined with PEGASYS(R) and COPEGUS(TM), Shows Potent Antiviral Activity in Treatment of Chronic Hepatitis C at Four Weeks
... (41%), myalgia (40%),
irritability/anxiety/nervousness (33%), insomnia (30%), alopecia (28%),
neutropenia (27%), nausea/vomiting (25%), rigors (25%),
anorexia (24%),
injection site reaction (23%), arthralgia (22%), depression (20%), pruritus
(19%) and dermatitis (16%). Serious adverse events in hepatitis C ...
Long-Term Data from a Landmark Phase III Trial Show Survival Benefit at Three- and Four-Years in Patients with Glioblastoma multiforme
... glioblastoma multiforme, during the concomitant
phase (TEMODAR plus radiotherapy) side effects including thrombocytopenia,
nausea, vomiting,
anorexia and constipation, were more frequent in the
TEMODAR plus radiotherapy arm. The most common side effects across the
cumulative TEMODAR experience were ...
CuraGen and TopoTarget Announce Presentation of Belinostat Clinical Trial Results at AACR-NCI-EORTC International Conference
... received a median of two treatment cycles (range 1 -
11) with fifteen patients ongoing. The most frequent adverse events
reported were fatigue,
anorexia and nausea. More than 2400 ECGs were
collected in this trial, with no grade 3 or 4 QTc changes noted. During the study, 15 patients (25%) achieved ...
Studies Showing Significant Survival Improvement with Taxotere(R)-based Regimens in the Induction Treatment of Patients with Locally Advanced Head and Neck Cancer are Published in the Same Issue of the New England Journal of Medicine
... 21%), lethargy (10% vs.
5%) and vomiting (10% vs. 8%). The incidence of other grade 3/4 events was
similar between the two groups, such as nausea,
anorexia and constipation. Head and Neck Cancer, a Deadly Disease More than 640,000 people worldwide are diagnosed with head and neck
cancer each year, and ...
Roche Announces Positive Results in Solid Tumors Using Human Monoclonal Antibody Against IGF-1R (R1507)
... with cancer therapy (e.g., low blood counts,
infection, hair loss, severe nausea and vomiting). The most frequent side
effects observed were fatigue,
anorexia and weight loss, symptoms that are
commonly observed in patients with advanced cancer. "We are very encouraged by these early results with R1507 in ...
Taxotere(R) (docetaxel) Granted FDA Approval to Treat Locally Advanced Head and Neck Cancer Prior to Chemoradiotherapy and Surgery
... 21%), lethargy (10% vs.
5%) and vomiting (10% vs. 8%). The incidence of other grade 3/4 events was
similar between the two groups, such as nausea,
anorexia and constipation. Head and Neck Cancer, a Deadly Disease More than 640,000 people worldwide are diagnosed with head and neck
cancer each year, and ...
Phase III Clinical Trial in Newly Diagnosed Multiple Myeloma Stopped Early Due to Highly Significant Efficacy Advantage of VELCADE(R) (Bortezomib) for Injection Based Therapy Across All Endpoints
... (64%), nausea (55%), diarrhea
(52%), constipation (41%), peripheral neuropathy (39%), thrombocytopenia
(36%), appetite decrease, including reports of
anorexia (36%), pyrexia
(34%), vomiting (33%) and anemia (29%). Twenty percent of patients reported
at least one episode of grade 4 toxicity; the most common ...
Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
... VELCADE, diarrhea (52%),
constipation (41%), peripheral neuropathy (39%), thrombocytopenia (36%),
appetite decrease, including reports of
anorexia (36%), pyrexia (34%),
vomiting (33%) and anemia (29%). Twenty percent of patients reported at
least one episode of grade 4 toxicity; the most common ...
Lilly Studies Try to Shed Light on Impact of Race on Lung Cancer
Treatment
... (7%); nausea (84%); vomiting (58%);
constipation (44%);
anorexia (35%); stomatitis/pharyngitis (28%);
diarrhea (26%); dyspnea (66%); chest ... common clinically relevant adverse events (all grades)
were fatigue (87%);
anorexia (62%); nausea (39%); constipation
(30%); vomiting (25%); diarrhea (21%); ...
Ontak (denileukin diftitox) Achieves 49.1% Overall Response Rate in
Phase III Trial of Cutaneous T-Cell Lymphoma (CTCL)
... (19%), cough (19%), asthenia (18%),
pruritus (17%), back pain (17%),
anorexia (15%), arthralgia (14%)
and upper respiratory tract infection (13%).
The ... (61%), infection (48%), pain (48%), edema
(47%), hypotension (36%),
anorexia (36%), and rash (34%).
Post Marketing
The following adverse reactions ...
Millennium Discovers Biomarkers Potentially Predictive of Response
to Velcade (Bortezomib) for Injection
... (64%), nausea (55%), diarrhea (52%),
constipation (41%), peripheral neuropathy (39%), thrombocytopenia
(36%), appetite decrease, including reports of
anorexia (36%),
pyrexia (34%), vomiting (33%) and anemia (29%). Twenty percent of
patients reported at least one episode of grade 4 toxicity; the
most common ...
New Pfizer Oncology Data Across Numerous Cancer Types to be
Presented at ASCO
... mucositis/stomatitis, vomiting, dyspensia,
abdominal pain, constipation, hypertension, rash, hand-foot
syndrome, skin discoloration, altered taste,
anorexia and
bleeding.
For more information on Sutent and Pfizer Oncology please visit
www.pfizer.com.
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