Dade Behrings (hsCRP) Tests and BNTM Series Analyzers
...nning analyses. The test is based on nephelometric analysis of latex particles coated with CRP monoclonal antibodies, which is much more sensitive than prior manual ELISA testing for CRP levels. Current AHA and CDC guidelines indicate that while this test should not be used as routine screening for the genera...Monitoring Patient Glucose Levels: New Advances in software make it easier
...cose values are automatically downloaded daily for analysis and can be sent to a secure web site online. The physician can log onto the secure web site to view a graph of daily glucose levels for patients, read a summary of relevant statistics for the sensor and calibration readings, and look at a combined mo...Digital vs. Analog Mammography
... with patient information such as risk probability analysis or other pertinent personal history data for impro...graphy for all but the thinnest breasts. Another analysis of the comparative performance of 18 digital mammography systems and 38 screen-film mammography syst...Prothrombin Time Comes in Small (CLIA-Waived) Packages
...or health care professionals to enable on-the-spot analysis of coagulation levels during mobile emergency treatment, in hospital and in general practice. The device employs electromagnetic field kinetics to determine PT. A single drop (10 l) of capillary or venous whole blood is applied to a test strip contai...Lab Automation Networks Proliferating
...integrate with specific Olympus analyzers to yield analysis of from 2,400 to 4,266 tests per hour. Another closed system design comes from Bayer HealthCare Diagnostic Division, Tarrytown, N.Y., a unit of the German firm Bayer AG, in the form of its ADVIA LabCell Modular Automation System. This system provides...Genetic Analysis Systems Enter the Clinical Mainstream
...estricted to large specialty laboratories, genetic analysis is entering the clinical mainstream. Smaller, simp...signed for a wide range of sequencing and fragment analysis applications and suitable for research, clinical, or forensic labs. This system does not require gel...New Point-of-Care Methods to Measure Coronary and Cerebrovascular Risk
...roke. This risk was similar even when statistical analysis controlled for the vascular risk factors mentioned...ls. The correlation held up even when statistical analysis controlled for other risk factors. The PREVU(x) test requires only two drops of solution placed on t...New Quality Control Systems for Every Laboratory Application
...ser support program, assisting customers with data analysis to track the performance of their assays. With the...d up by good customer service and appropriate data analysis programs from the vendor. Fortunately, new QC materials are keeping pace with the demands of laborat...Hematology Analyzers Simple, Sophisticated Technology Serving All Patients
...ophisticated analyzers, dual angle optical scatter analysis combines optical signals from two independent ligh... programs ranging from basic QC data retrieval and analysis to internet-based real-time data sharing systems. Beyond improving user safety and convenience, thes...Blood Gas Analysis: The Pros and Cons of Point-Of-Care Testing
...e the first system was invented in 1957, blood gas analysis has revolutionized clinical medicine and patient care. During the 1960s, blood gas analysis became almost universally available, and blood gases were considered "the most important laboratory ...Near-Patient Testing: The Advantages of C-Reactive Protein in Hematological Testing
...rements in some instances. Based on solid clinical analysis and a few simple laboratory tools, such as CBC and... fluctuations during fever. This allows a dynamic analysis of the infection progression and can lead to more accurate and prompt administration of antibiotic t...Optimizing Quality Control Data Management
...quality control data review Provides advanced data analysis charts and reports Enables the consolidation of qu...lso use Unity Real Times Bench Review for run-time analysis and Supervisor Review for periodic supervisory data analysis. Bench and Supervisor Review Unity R...Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
...rsparticipating in the trial and by an independent analysis ofpatient scans; time to tumour progression (a mea...One patient in the ASA404 arm wasexcluded from the analysis of survival and one patient in thechemotherapy-alone arm was excluded from the independent analyseso......arin40 mg). Also presented at ISTH was a pooled analysis of major VTE andVTE-related mortality after primar...MOBILIZE(TM) and RE-NOVATE studies).(ii) Thepooled analysis concluded that dabigatran etexilate wasnon-inferior to enoxaparin in the prevention of major VTE and......to discussing theseresults and our planned interim analysis of the PIX301 (EXTEND)pivotal trial with the FDA. ...proximately half of study participants. Theinterim analysis was conducted after approximately 60 patientscompleted at least four cycles of therapy to determine ......y completed modeledpopulation pharmacokinetic (PK) analysis used to estimate theeffect of steady state co-admi...n the study. -- The modeled population PK analysis estimated a 59% maximal increase in the relative SC bioavailability of adalimumab at steady st...Protox Announces Positive Clinical Data from Prostate Cancer Study
... that will include top-linePSA data with expanded analysis of PSADT and PSAV will beavailable for release in October. Plans are underway tocommence a Phase 2 study before the end of the year. Conference call Protox will host a conference call and live webcast today at12:00 p.m. E.T. to discuss th......trand breaks such as those caused bycisplatin. The analysis of ERCC-1 levels in this study wasconducted by Res...hnologies. RGI's technologies enableextraction and analysis of genetic information from genes derivedfrom tumor samples stored as formalin-fixed and paraffin em......CDAD and the timing of suchdiscussions; additional analysis of the data from the first Phase 3study; the results of the second Phase 3 study and whether suchresults are consistent with this data; the timing of the secondPhase 3 study; and the risks and uncertainties described in reportsfiled by Genzyme with t......y 05, 2007 /PRNewswire/ -- Results fromthe primary analysis of a randomized, controlled, open-label, Phase3 st...versity of Illinois, Chicago. The 48-week primary analysis from the TITAN study providesadditional information regarding efficacy and safety of PREZISTA/rin co......thus better meet patients' requirements." Further analysis of the data is ongoing. About Cosmo Pharmaceuticals Cosmo is a speciality pharma company that aims to become aglobal leader in optimised therapies for certain gastrointestinaldiseases. The company's proprietary clinical developmentpipeline spe...Skin Rash Actually Signifies Better Outcomes for Pancreatic and Lung Cancer Patients
...factor receptor– but it is the most detailed analysis todate. The study, published in the July 1 issu... EGFR inhibition in skintissue, Wacker said. The analysis looked at two placebo-controlled, double-blind,randomized, Phase III clinical trials testing Tarceva...Researchers Discover Method for Identifying How Cancer Evades the Immune System
...ral defenses. Intime, the researchers believe such analysis could become a standardpractice in cancer diagnosis and treatment. “The implication is that once you know the mechanism by whichtumors evade the immune system, you can match that tumor toavailable therapies,” said senior author Alan L.E...Ablynx Announces Interim Results of First Nanobody Phase I Study of ALX-0081 (ANTI-VWF)
...iated during the first quarter of 2007. Theinterim analysis indicates: - the desired pharmacodynamic effect was observed as anticipatedindicating the high potency of ALX-0081 - ALX-0081 was well tolerated and showed no serious adverseeffects or dose limiting toxicity The final results are anticipated to ......onsiderations For Non-Inferiority For statistical analysis pursuant to the Company's protocol andconsistent w...approved as a treatment for CAP, and datafrom this analysis have not been reviewed by the FDA. Update to Trial CL-05 Timeline The Company also updated the pro...Major New Review Supports the Broader Potential of CeNeS COMT Inhibitor Discovery Programme
... paper's authors collate recent developments inthe analysis of the role of COMT genotypes and their involvement incognitive deficits in schizophrenia and bipolar disorder. The papersupports the view that there is potential to use COMT inhibitors inameliorating their cognitive deficits via an effect on prefron...Alkermes Announces Positive Results from Phase 1/2 Clinical Study of ALKS 29
...comes for patients. We look forward to thecomplete analysis of these data, as we believe insights from thisstudy could help pave the way for the development of ALKS 29 andother proprietary oral compounds for the treatment of alcoholdependence." In the phase 1/2 study, patients treated with ALKS 29demonstra......dpositive safety and efficacy data from an interim analysis of thisstudy. The poster presented at the ESMO conference shows efficacydata in a case study for the first time. Dr. Ulrich Delvos, Chief Operating Officer of MediGene,comments. "We are delighted and proud that the European Society forMedical Onco...... efficacy inuntreated MM patients. The preliminary analysis included 15evaluable patients, who received VELCADE at 1.0 mg/m(2) or 1.3mg/m(2) on days 1, 4, 8 and 11 of a 21- day schedule. Patients alsoreceived lenalidomide at 15, 20 or 25 mg on days 1 through 14 anddexamethasone at 40 mg corresponding with the......7 /PRNewswire-FirstCall/ -- Resultsfrom an interim analysis of a Phase III study show thatCERVARIX(R), the Gla...ity of precancerous lesions included inthe primary analysis had multiple cancer-causing virus typesdetected, making it difficult to clearly determine which viru...CombinatoRx Product Candidate CRx-150 Shows Activity on DAS28 and Pain, but Not CRP
...rol) in subjects with active RA.In the preliminary analysis of this trial, CRx-150 demonstratedstatistically significant effects on DAS28 and pain, a trend onACR20 and no effect on CRP. -0- Measure Regimen ITT Population PP Population------------------------------------------------------------DAS......ing that 50% of the patients in theblinded interim analysis should be on SinuNase, and 50% on placebocontrol. "The data reported is very encouraging," said Dr. Frank E.O'Donnell Jr., Chairman and Chief Executive Officer of AccentiaBiopharmaceuticals. "While we cannot determine which patients arereceiving Si...... in Transition's press release on March 5th, 2007, analysis ofefficacy parameters was performed on type 2 diabetes patients withHbA1c levels of equal to or greater than 7% prior to treatment. In the E1-I.N.T.(TM) treated group of patients, the mean HbA1clevel was reduced by 0.94% to 1.21% vs. baseline levels......liminary findings. TheLFA looks forward to further analysis of the data and will reportthis information as soon as it becomes available. About the LFA: The Lupus Foundation of America is the nation'sleading nonprofit voluntary health organization dedicated tofinding the causes and cure for lupus. The LFA and......; the FDA may determine that the design andplanned analysis of our clinical trials do not adequately addressthe trial objectives in support of our regulatory submission;future sales of CellCept may be less than expected; our futureoperating results are uncertain and likely to fluctuate; we may notbe able to d......maryendpoint, the FDA may require additional data, analysis or studiesbefore the NDA is approved by the FDA; the outcome of anydiscussions with the FDA; the initiation, timing, design,enrollment and cost of clinical trials; unexpected delays inclinical trials and preparation of materials for submission to the...ACE-011 Improves Multiple Myeloma Bone Disease in a Preclinical Model
...eloss as a result of the myeloma. Histomorphometry analysis revealedthat mice treated with ACE-011 had normal bone formationparameters, while untreated mice had reduced bone formation andincreased bone resorption. Furthermore, ACE-011 preserved thenumber of osteoblasts, the cells responsible for forming new b...... monotherapy. The results of the betacell modeling analysis showed that the addition of JANUVIA tometformin re...harmacokinetics ofsitagliptin based on a composite analysis of Phase I pharmacokineticdata and on a population pharmacokinetic analysis of Phase I and PhaseII d......he new data presented at ADA were from a six-month analysis of5,604 Type 2 diabetes patients, in a mainly primary care settings,and predominantly treated with Levemir® once-daily, as anadd-on therapy to any other glucose-lowering regimens, or asreplacement of a previous basal insulin. Patients wererandom......, comparedwith placebo. The results are from a new analysis of the landmarkStroke Prevention by Aggressive Red...klin University ofMedicine & Science. "In this analysis of patients with type 2diabetes with no known coronary heart disease, we found Lipitor tobe effectiv......f 8.3), weresubjected to a pre-specified secondary analysis focused onCycloset(TM)'s ability to reduce HbA1c after 24 weeks of therapy.Those receiving Cycloset(TM) and completing 24 weeks of therapy(121 subjects) experienced a mean HbA1c reduction of 0.69 (P =0.0002) compared to respective placebo (71 subject......is a patient's startinglevel of A1C. In a subgroup analysis of patients grouped byseverity of starting baselin...Merck expects FDA action by mid-October. A pooled analysis of 5,141 patients showed overall incidence ofadverse experiences, incidence of serious adverse exper......ould be affected by,among other things, additional analysis of clinical data; newclinical data; unexpected clinical trial results; unexpectedregulatory actions or delays in government regulation generally;the company's ability to obtain or maintain patent or otherproprietary intellectual property protection; ......he new data presented at ADA were from a six-month analysis of5,604 type 2 diabetes patients, in a mainly primary care settings,and predominantly treated with Levemir(R) once-daily, as an add-ontherapy to any other glucose- lowering regimens, or as replacementof a previous basal insulin. Patients were randomi......igham and Women's Hospital in Boston. The interim analysis compared pregnancy rates and patientpreferences am...ive officer of ColumbiaLaboratories. "The interim analysis shows women receiving CRINONE 8% reportedfewer side effects and greater overall satisfaction versus ......hiral Pool, Resolution, Biocatalysts, orasymmetric analysis creates the required compounds. The majority ofdevelopment activity is routed through fine chemical companieswhich are additionally trying to upgrade their capabilities inorder to provide to the entire portfolio of pharmaceutical drugsfor application...GenoLogics Announces Bioinformatics Partnership with Illumina
...blished by Illumina to advancedata integration and analysis among the life science community. GenoLogics will...ffering Geneus with integrations to theirBeadArray analysis software, BeadStudio, which will enable ourcustomers with gene expression and genotyping application......s and reduced glomerular filtration rate: an analysis from PROactive; Poster 0671-P presented on S... 6:15-7:30 p.m. -- Long-term cost-effectiveness analysis on ACTOS for the USA from PROactive; Poster 1209-P presented on Sunday, June 24, from 12-2 p.m......shown to be safe and effective. The "per-protocol" analysis ofTovaxin therapy achieved a 92% reduction in annualized relapse rate(ARR) in subjects who received two treatment doses of 30 - 45 x10(6) attenuated T-cells eight weeks apart and were monitored foran additional 44 weeks. Subjects in the extension stu......ompared with those in the placebogroup. "Recent analysis of the data from the WHI study haveconsistently clarified the initial data, to show that in the newlydiagnosed population of menopausal women, estrogen therapy does notincrease cardiovascular disease and that there actually is astatistically signific...Cethromycin Achieves Primary Endpoint in Pivotal Phase 3 Pneumonia Clinical Trial
...approved as a treatment for CAP, and datafrom this analysis have not been reviewed by the FDA. No furtherdetails of the clinical study will be available until all dataanalyses are complete and results are presented in a public,scientific forum. Program Design The Phase 3 CAP clinical trial program is compri......ived WBRTalone, according to a stratified log rank analysis of overallsurvival (8.5 months vs. 7.5 months; haz...arfollowing completion of a pre- specified interim analysis ofresponse data after 35 patients have completed at least one cycleof treatment with PDX." About PD...Vical Licensee AnGes MG Announces Positive Results of Phase 3 Angiogenesis Trial in Japan
...G,Inc. reported positive results following interim analysis of datafrom the first 41 subjects to complete a Ph... Gene Therapy in Japan AnGes conducted an interim analysis of the PIII data using HGFGene (AMG 0001) for Critical Limb Ischemia (CLI) in Japan, and ispleased t...New Flu Vaccine from PepTcell Could Provide Immunity Against All Strains of Influenza Virus
...gions inanimal and human strains of flu virus. The analysis identified sixhighly conserved regions within several proteins that are capableof triggering an immune response. These six regions were then chemically synthesised as smallprotein fragments called peptides. The resulting preparation,FLU-v, was used ......hing fromtamoxifen to anastrozole (ArimidexTM). An analysis of the‘Arimidex’-‘Nolvadex&rsquo...ent for early-stagebreast cancer: long-term safety analysis of the ATAC trial. LancetOncology 2006; 7 (8): 633-643 [v] Saphner T, Tormey DC and Gray R. Annual ......n.Echocardiographic and magnetic resonance imaging analysis showedthat the animals transplanted with GRNCM1 cells had improved(smaller) end-left ventricular systolic and diastolic diameters,increased fractional shortening, improved infarct wall thickeningand increased ejection fraction compared to control ani...Genzyme Announces Results of Clinical Trials Investigating Powder Form of Sevelamer Carbonate
...and uncertainties include,among others: additional analysis of the data comparing the powderform of Renvela™ to Renagel®; the results of otherstudies and whether such results are consistent with this data; theactual efficacy and safety of Renvela™ for chronic kidneydisease; the outcome of disc...Genzyme Announces Results of Clinical Trials Investigating Powder Form of Sevelamer Carbonate
...and uncertainties include,among others: additional analysis of the data comparing the powderform of Renvela(TM) to Renagel(R); the results of other studies andwhether such results are consistent with this data; the actualefficacy and safety of Renvela(TM) for chronic kidney disease; theoutcome of discussions ...New Flu Vaccine From PepTcell Could Provide Immunity Against All Strains of Influenza Virus
...gions inanimal and human strains of flu virus. The analysis identified sixhighly conserved regions within several proteins that are capableof triggering an immune response. These six regions were then chemically synthesised as smallprotein fragments called peptides. The resulting preparation,FLU-v, was used ......tching fromtamoxifen to anastrozole (Arimidex). An analysis of the'Arimidex'-'Nolvadex 95' (ARNO 95) study, published online in TheJournal of Clinical Oncology, confirms that postmenopausal womenwho have been taking tamoxifen as part of their treatment for earlybreast cancer for two years can significantly re...