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VisEn Molecular Imaging Technology Enables Key Insights Into Newly Discovered Biologic Pathway Published in SCIENCE

... technology and activatable in vivo imaging agents were able to help the research team answer some ... efficacy in vivo . VisEn's FMT systems and agents are used by leading research institutions and ... to design ranges of tailored molecular imaging agents and applications designed for their specific ...

New Studies Presented at European Society of Anaesthesia Further Validate Masimo PVI(TM) for Noninvasive and Continuous Fluid Monitoring

... Index After Administration of General Anesthetic agents In this study, anesthesiologists at the ... After administration of general anesthetic agents and 10ml/kg/hr of fluid during induction, PVI ... "after administration of general anesthetic agents and intravenous fluid administration during ...

New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients

... with anti-tumor necrosis factor (TNF)-alpha agents and received subcutaneous injections of ... drug use, number of prior anti-TNF-alpha agents and reason for discontinuation of prior TNF ... received one, two and three prior anti-TNF-alpha agents in both placebo (74 percent, 77 percent, 71 ...

Proteolix Presents Positive Clinical Data for Carfilzomib in Multiple Myeloma at the 2009 ASCO Annual Meeting

... the treatment of multiple myeloma, new selective agents are needed for patients who have failed other ... having failed prior treatment with all approved agents and stem cell transplant." Sustained ... options that include combination chemotherapeutic agents and stem cell transplantation. While many ...

Raptor Pharmaceuticals Receives Notices of Allowance for Two NeuroTrans(TM) Patent Applications

... titled " Methods of increasing delivery of active agents to brain comprising administering ... protein ("RAP") fragments conjugated to active agents ." (Logo: ... in the delivery of diagnostic and therapeutic agents across the BBB into the central nervous system ...

Emerging Therapies Could Help Ease The Chronic Symptoms of Atopic Dermatitis For Adults and Children

... emollients are newer FDA-approved topical agents that are designed to improve the barrier function ... lipids that act as water regulators) or other agents that help to make damaged skin more "normal." ... that a few of the newer immunosuppressive agents and newer biologic therapies are being used ...

Chemoembolization Improving as Liver Cancer Treatment

... are combined with cancer-killing chemotherapeutic agents and then delivered to the blood vessels. The ... HepaSphere(TM) beads loaded with chemotherapeutic agents to deliver treatment to 53 patients with liver ... without the addition of any chemotherapeutic agents in the beads. The patients had 35 sessions with ...

Late-Breaking Data Highlighting Research Advances in Several Blood Disorders to Be Presented At the American Society of Hematology Annual Meeting

... with cancer taking erythropoiesis-stimulating agents (ESAs) for the treatment of anemia, and the ... Recombinant Human Erythropoiesis Stimulating agents in Cancer Patients: Individual Patient Data ... affected by the use of erythropoiesis-stimulating agents (ESAs) for the treatment of anemia in patients ...

Third Pivotal Phase 3 Study for NicOx' Naproxcinod Shows Positive Efficacy, Safety and Blood Pressure Results

... compound in a novel class of anti-inflammatory agents known as Cyclooxygenase-Inhibiting Nitric ... Few studies with other anti-inflammatory agents have focused only on people with hip OA, in ... Oxide-Donating (CINOD) class of anti-inflammatory agents for the treatment of the signs and symptoms ...

Anadys Pharmaceuticals Announces Single Dose Safety and Pharmacokinetics Results for ANA598 in Healthy Volunteers

... Demonstrate that Combinations of Antiviral agents that Include HCV Polymerase Inhibitor ANA598 have ... to be used in combination with multiple other agents approved or under investigation for hepatitis C. ... of treatment if doses of currently used agents can be reduced or eliminated. About Anadys ...

PharmAthene Initiates Phase I Clinical Trial of Nerve Agent Bioscavenger Protexia(R)

... Protexia(R) used as a prophylactic against nerve agents might offer important benefits over ... or civilian victims of nerve agent attacks. Nerve agents belong to a class of compounds known ... or absorption through the skin. The nerve agents travel in the circulatory system to the brain and ...

Long-Term Study Evaluates Boosted PREZISTA(R) Vs. Lopinavir/Ritonavir as Part of HIV Combination Therapy in Treatment-Naive Adults

... the 48th Interscience Conference on Antimicrobial agents and Chemotherapy (ICAAC) in Washington, DC. ... the use of PREZISTA/r. The use of other active agents with PREZISTA/r is associated with a greater ... Caution should be used when prescribing agents such as sildenafil, vardenafil, tadalafil, or ...

Paratek Reports Positive Phase 2 Clinical Data on its New Antibiotic PTK 0796 in Late Breaker Presentation at the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy

... the 48th Interscience Conference on Antimicrobial agents and Chemotherapy (ICAAC), taking place in ... tetracycline antibiotics as potential agents to combat multiple antibiotic-resistant bacteria, ... remain among the most commonly used antiinfective agents to combat bacterial infections. However, the ...

PharmAthene Presents Data for Protexia(R) and Valortim(R) at 2008 BARDA Industry Conference / PHEMCE Stakeholders Workshop

... or civilian victims of nerve agent attacks. Nerve agents belong to a class of compounds known as ... or absorption through the skin. The nerve agents travel in the circulatory system to the brain and ... associated with exposure to chemical nerve agents -- RypVax(TM) -- a recombinant dual antigen ...

Palatin Technologies Presents PL-3994 Clinical Trial Results at the 12th Annual Scientific Meeting of the Heart Failure Association of America

... is clearly a significant medical need for newer agents which can provide further improvement." About ... number of physiologic functions, and therapeutic agents modulating this system may have the potential to ... cardiovascular functions, and therapeutic agents modulating this system may be useful in treatment ...

Omeros Announces Patient Enrollment in Phase 1/Phase 2 Study of OMS302

... Chairman and CEO of Omeros. "Each of the two agents in OMS302 is currently used individually and ... during eye surgery. OMS302 combines these two agents and their pharmacologic activities into a single ... are proprietary combinations of therapeutic agents designed to act simultaneously at multiple ...

FluoroPharma Announces Positive Phase I Safety Results for BFPET(TM), Myocardial Perfusion Imaging (MPI) Tracer for Positron Emission Tomography (PET)

... company developing breakthrough molecular imaging agents for the Positron Emission Tomography (PET) ... this study indicate that new cardiac PET imaging agents can expand the applications of PET beyond the use ... in oncology and neurology. With two cardiac agents in clinical development and a third in our ...

Peregrine Pharmaceuticals Awarded Two New U.S. Patents Broadening Its Targeted Anti-Phospholipid Patent Portfolio

... Cover Anti-Viral Applications of Novel Targeted agents Under the Company's Anti-Phospholipid ... Platform - - Anti-Viral Potential of These New agents Supported by Recent Studies Presented at ... PE-binding peptides attached to anti-viral agents as well as those conjugated to antibodies ...

Cardinal Health Expands PET Nuclear Pharmacy Services to Support Clinical Drug Trials

... manufacturers expand the pipeline of new agents that will aid in the diagnosis and treatment of ... master files to the FDA for several of the PET agents it manufactures. These files contain detailed ... others in the pharmaceutical industry to test PET agents in the treatment or diagnosis of disease without ...

Abbott Presents Long-Term Data From Extension Study Showing Adult Crohn's Patients Treated With HUMIRA(R) (Adalimumab) Maintained Remission

... including those who were naive to anti-TNF agents or who had previously lost response or were ... and/or immunomodulatory agents (e.g. 6-mercaptopurine and azathioprine) may be ... in patients also taking other immunosuppressive agents that in addition to their underlying ...

Roche Gains Access to Important Oncology Target With Potential for Treating Major Cancers Such as Breast and Lung; First Drug Candidate in Phase I Clinical Testing

... of resistance to potential chemotherapeutic agents targeting the epidermal growth factor ... the potential widespread anti-cancer utility of agents that inhibit the pathway at the level of PI3-K, particularly the alpha isoform. Such agents are expected to inhibit proliferation and ...

Semafore's PI3 Kinase Inhibitor SF1126 is a Vascular Targeted Conjugate in Phase I Clinical Trials in Solid Tumors and Multiple Myeloma

... with either agent alone or where the two agents were administered sequentially. Angiogenesis ... rationale for combining targeted therapeutic agents in oncology to improve efficacy," said Dr. ... and this increased effect was optimal when the agents were administered in combination as opposed to ...

FluoroPharma Announces Commencement of Phase I Clinical Trial for BFPET(TM), Myocardial Perfusion Imaging (MPI) Tracer for Positron Emission Tomography (PET)

... breakthrough cardiovascular molecular imaging agents for the Positron Emission Tomography (PET) ... cardiovascular disease with multiple PET imaging agents targeting a wide range of indications." About ... and chronic forms of coronary disease. These agents have been designed to rapidly target either the ...

HUYA Bioscience Int'l Announces World-Class Clinical Advisory Team for New Anti-Arrhythmic Compound Sourced From China

... afflicts 5.6 million Americans. Anti-arrhythmic agents have also been used for the treatment of ... drugs. Development of safe anti-arrhythmic agents for use in these patients is needed. ... may have safety advantages over other anti-AF agents and exhibits broad spectrum ion channel ...

HUYA Bioscience Int'l Announces Clinical Trial Milestones in China for Promising New Anti-Arrhythmic Compound; Data Supports Desirable Safety Profile

... afflicts 5.6 million Americans. Anti-arrhythmic agents have also been used for the treatment of ... drugs. Development of safe anti-arrhythmic agents for use in these patients is needed. ... may have safety advantages over other anti-AF agents and exhibits broad spectrum ion channel ...

FluoroPharma Announces Positive Phase I Safety Results for CardioPET(TM), Coronary Artery Disease (CAD) Imaging Tracer for Positron Emission Tomography (PET)

... cardiovascular molecular imaging agents for the Positron Emission Tomography (PET) ... two other cardiovascular PET molecular imaging agents -- BFPET for assessment of myocardial ... and chronic forms of coronary disease. These agents have been designed to rapidly target either the ...

OPKO Health and Pathogenics Announce Data Publication Demonstrating the Potential Utility of NCT in a Severe Eye Infection

... in the current edition of Antimicrobial agents and Chemotherapy.* Led by Dr. Ursula Furnkranz ... on Acanthamoeba spp," Antimicrobial agents and Chemotherapy. (Furnkranz, U et al. ... edema. OPKO is developing a pipeline of novel agents for ophthalmic diseases and markets innovative ...

Oncology Drug Development Update - Molecular Profiling Redefines the Nature of Malignancy and Increases the Adoption of Targeted Therapeutics

... markers. In each of these cases novel targeted agents and various combination strategies are being ... their updated treatment guidelines. Targeted agents in Combination are Entering Clinical Trials The ... will not be measured until approved and novel agents are combined in hundreds of different ...

Supplemental New Drug Application for PREZISTA(TM) Submitted to U.S. Food and Drug Administration

... use of PREZISTA/r. -- The use of other active agents with PREZISTA/r is associated with a greater ... the 47th Interscience Conference on Antimicrobial agents and Chemotherapy (ICAAC) in Chicago on September ... Caution should be used when prescribing agents such as sildenafil, vardenafil, tadalafil, or ...

PROCRIT(R) (Epoetin Alfa) Data to be Presented at American Society of Hematology Annual Meeting

... the use of erythropoiesis-stimulating agents (ESAs) for the treatment of ... Considerations of Erythropoiesis- Stimulating agents in Patients with Myelodysplastic Syndromes ... Patterns -- Poster: Erythropoiesis-Stimulating agents for Chemotherapy Induced Anemia: Analysis of ...

Preclinical Studies Show Potential Progress Toward Identifying Specific Tumor Types With Higher Likelihood of Demonstrating Response to Anti-Cancer Compounds Early in Clinical Development

... cancer: role of combination with hypomethylating agents (Abstract #A288) Data were presented that show brostallicin, when combined with hypomethylating agents such as zebularine, may convert resistant ... cancer and that the use of other hypomethylating agents in combination with brostallicin should be ...

Aptivus(R) (tipranavir) Capsules Granted Full Approval by the U.S. FDA

... is not recommended. -- The use of other active agents with APTIVUS/r is associated with a greater ... from at least three classes of antiretroviral agents and had documented PI resistance. At the time of ... the risk of bleeding such as antiplatelet agents and anticoagulants, or who are taking ...

Replidyne's Investigational Antibacterial Agent REP3123 Prevents Toxin Production in Clostridium difficile

... Conference on Antimicrobial agents and Chemotherapy LOUISVILLE, Colo., Sept. 19 ... Annual Interscience Conference on Antimicrobial agents and Chemotherapy held at the McCormick Place ... strains tested. In contrast, widely used agents such as vancomycin and metronidazole did ...

Promising Data from Paratek Pharmaceuticals' MAR Inhibitor Program Presented in 'Late Breaker' Session at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy

... the 47th Interscience Conference on Antimicrobial agents and Chemotherapy (ICAAC) taking place in Chicago. The findings demonstrated that small molecule agents which block the activity of ExsA (a MAR protein) ... controlling virulence, and act as effective agents for preventing infection. MAR inhibitors are also ...

New Phase 3 Study in Treatment-Naive Adults with HIV Evaluates Efficacy and Safety of Once-Daily PREZISTA(TM)/ritonavir vs. KALETRA(R) as Part of HIV Combination Therapy

... the 47th Interscience Conference on Antimicrobial agents and Chemotherapy (ICAAC) in Chicago. It is the ... use of PREZISTA/r. -- The use of other active agents with PREZISTA/r is associated with a greater ... Caution should be used when prescribing agents such as sildenafil, vardenafil, tadalafil, or ...

Raptor Pharmaceuticals Provides Update of Product Programs

... studies. Conjugates of HepTide and antiviral agents could significantly improve accumulation of these agents in the liver and reduce the amount of powerful antiviral agents elsewhere in the body. Stanford University Grant ...

Advanced Life Sciences to Present Data on Selected Cethromycin Therapeutic Studies at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy

... the 47th Interscience Conference on Antimicrobial agents and Chemotherapy (ICAAC) at McCormick Place ... Session 222: Pathogenesis and Therapeutics in agents of Bioterrorism -- Poster: Poster B-2031: ... the 47th Interscience Conference on Antimicrobial agents and Chemotherapy (ICAAC), which will be held in ...

Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML

... we find new effective treatment options. agents such as Cloretazine(R) (VNP40101M) have the ... innovative cancer therapeutics. Vion has two agents in clinical trials. Cloretazine(R) (VNP40101M), a ... vector used to deliver anticancer agents directly to tumors. For additional information on ...

Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel Once Daily Anti-Epileptic Zebinix(R)

... and cognitive slowing, are highly prevalent with existing anti-epileptic agents and may affect as many as 97% of patients(7). Hence, there is a need for new anti-epileptic agents that offer effective reduction in seizure frequency combined with a ...

Responses After Completion of Therapy Increase Pixantrone Complete Remission (CR)/Unconfirmed Complete Remission (CRu) Rate to 24% and Overall Response Rate (ORR) to 40% Compared to 7% and 14% for Comparator Agents in Phase III EXTEND Trial in 3rd Line Th

... reported clinical trials investigating pixantrone combined with other agents in indolent NHL is being reviewed. In one trial, PIX 302, patients that ... treated with pixantrone than among patients who received comparator agents (8.8% vs. 4.5%). Events considered cardiac disorders included cardiac ...
Other Contents
(Date:7/9/2014)... Sexual selection refers to species, selection for traits that ... of natural selection enhances opportunities to mate, the tail ... at the University of California, Riverside have now found ... a placenta are linked. Describing the life histories ... family Poeciliidae, the researchers found that species with placentas ...
(Date:7/9/2014)... (TCGA) Research Network have identified novel mutations in ... most common subtype of lung cancer. Knowledge of ... possible therapeutic targets for this disease and potentially ... mutations because many potent cancer drugs that target ... funded and managed by the National Cancer Institute ...
(Date:7/9/2014)... With grilling season upon us, many backyard cooks are ... fatty hot dogs. But low fat can sometimes mean ... addressing the texture problem in low-fat wieners that are ... study was published in ACS, Journal of Agricultural ... colleagues note that hot-dog consumers have come to expect ...
Breaking Biology News(10 mins):Biologists link sexual selection and placenta formation 2Biologists link sexual selection and placenta formation 3Biologists link sexual selection and placenta formation 4Study identifies novel genomic changes in the most common type of lung cancer 2Study identifies novel genomic changes in the most common type of lung cancer 3
(Date:7/9/2014)... The liver is one of the most important organs ... that we utilize our food properly this is ... removed from our organism this is its detoxification ... and unhealthy food all damage the liver. The resulting ... deposits, cirrhoses, and life-threatening liver failure. According to the ...
(Date:7/9/2014)... studies linking older age with kidney and heart disease ... donation among older adults. However, in the first study ... Perelman School of Medicine at the University of Pennsylvania ... enjoy similar life expectancy and cardiovascular health as very ... In light of the ever increasing organ transplant waitlists, ...
(Date:7/9/2014)... has risen dramatically in Western societies. One frequently cited ... and have fewer infections than previous generations, thereby delaying ... researchers at Sahlgrenska Academy, University of Gothenburg, monitored children ... the immune system in relation to allergic disease. All ... Vstra Gtaland Region, half of them on farms that ...
(Date:7/8/2014)... awarded up to $15 million by the Defense Advanced ... aiming to help brain-injured people restore lost memory functions. ... psychology and physics will collaborate to create, surgically implant, ... Memory is the process in which neurons in certain ... retrieve it. Certain types of illnesses and injuries disrupt ...
(Date:7/8/2014)... found to be three times higher when auditors were ... auditors present, according to a study in a major ... "Quantification of the Hawthorne effect in hand hygiene compliance ... study," published today on-line in the BMJ Quality ... Srigley, who did the study as part of her ...
Breaking Medicine News(10 mins):Health News:Telemedicine for patients with chronic liver diseases 2Health News:Telemedicine for patients with chronic liver diseases 3Health News:Penn study finds living kidney donation does not increase risk of death or heart disease for older 2Health News:DARPA awards UCLA $15 million to restore lost memory 2Health News:DARPA awards UCLA $15 million to restore lost memory 3Health News:Health-care worker hand hygiene rates increase three-fold when auditors visible 2Health News:Health-care worker hand hygiene rates increase three-fold when auditors visible 3
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