absorption

Halozyme Therapeutics' Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society

...M) Technology clinical trialdemonstrating improved absorption and bioavailability of arepresentative commerciall... using hyaluronidaseas an adjuvant to increase the absorption and dispersion ofco-injected small molecule drugs, to Halozyme's knowledge, this wasthe first clinic...

DOR BioPharma Announces Publication Describing Results of Its Multivalent Botulinum Toxin Vaccine BT-VACC

...ve the advantage tostimulate antibodies that block absorption of toxin into the body.We expect that the successful development of a multivalent oralbotulinum toxin vaccine that can be applied to rapidly deployablemass immunization programs will be a major step forward inBiodefense countermeasures." "These resu...

Novagali Pharma Presents at AACO the Results of its Pivotal Phase III Clinical Trial of Vekacia in Children Suffering From Vernal Keratoconjunctivitis

...sion enabling an efficient andunmatched-level drug absorption in tissues of the eye leading tooptimal therapeutic efficacy. About Novagali Pharma: <a target="_blank" href="http://www.novagali.com/">www.novagali.com Novagali Pharma SA is an emerging ophthalmic pharmaceuticalcompany based in the Genopo...

First Phase II Short-Term Study on Dapagliflozin Shows Results on Safety, Tolerability and Glycemic Markers in Subjects With Type 2 Diabetes

...models, indicates that modulation of renal glucose absorption withSGLT2 inhibition reduces blood glucose independent of insulinsecretion or action. Bristol-Myers Squibb and AstraZeneca Partnership In January 2007, Bristol-Myers Squibb and AstraZeneca enteredinto a collaboration to develop and commercialize sa...

Bentley Reports Positive Results with Nasulin Intranasal Insulin Spray at the American Diabetes Association Meeting

...udies to determine if smoking had any effect onthe absorption of Nasulin in normal male smokers and non-smokersand to determine if there were any absorption differences due tothe normal nasal cycles that occur between nostrils (alternatinglevels of mild con...

Eurand's Zentase Effective in Treating Exocrine Pancreatic Insufficiency, Studies Show

...cally andclinically significant improvement in the absorption of fat,protein and nutrients in patients suffering...is deficiency results in poordigestion and reduced absorption of nutrients, which, if leftuntreated, can lead to malnutrition, impaired growth, weakenedimmune res...

Javelin Pharmaceuticals Announces Successful Pivotal Phase 3 Trial Data

...hile pharmaceuticallyinert by itself, enhances the absorption of compounds acrossmucosal membranes, such as in t...ontribution ofChiSys(TM) to enhancing mucosal drug absorption reflects severalfactors including its potent mucoadhesive property, which preventsdrug washout. Rylo...

ProEthic Pharmaceuticals Presents Positive Data for PRO-513 at American Headache Society Meeting

...amic BufferingTechnology (DBT), which enhances the absorption of its activeingredient, diclofenac potassium. By utilizing potassiumbicarbonate as a localized buffer, DBT enables diclofenac to enterthe bloodstream more quickly, resulting in a faster rate of drugabsorption and increased peak plasma concentrations...

NovaDel Announces Positive Data from Two Studies Comparing Zolpidem Oral Spray to Ambien Tablets

...Delalso conducted assessments on the speed of drug absorption toattain therapeutic drug levels and an assessment of sedation. Theseresults will not be used by NovaDel for its NDA submission. Results of the Studies & Data to Support NDA Submission NVD003 Study - Healthy volunteers Pursuant to FDA guidance...

New Research Confirms the Benefit of Extended-Release Dipyridamole Plus ASA for Preventing Recurrent Stroke in Low- and High-Risk Patients

....4 This optimized formulation is buffered,allowing absorption despite fluctuations in the gastric acidity.This is particularly beneficial for elderly stroke patients in whomreduced gastric acidity or gastric and duodenal ulcer therapy iswidespread.5 Stroke is the third leading cause of death worldwide after he...

LifeCycle Pharma Announces Positive Phase I Clinical Results for its Transplantation Product Candidate, LCP-Tacro

...the low bioavailability ofPrograf(R), its variable absorption and interaction with food andother drugs. About LifeCycle Pharma A/S: LifeCycle Pharma, headquartered in H0rsholm, Denmark, is anemerging pharmaceutical company with a broad and late stage productpipeline in therapeutic areas of cholesterol managem...

Bentley Late Breaking Abstract Accepted for Poster Presentation at American Diabetes Association Scientific Sessions

... proprietary drug deliverytechnologies enhance the absorption of pharmaceutical compoundsacross various membranes. Bentley manufactures and markets agrowing portfolio of generic and branded generic pharmaceuticals inEurope for the treatment of cardiovascular, gastrointestinal,infectious and central nervous syst...

Sosei Announces Successful Completion of AD 923 Pharmacokinetic Study in the USA

...ctives of the study were achieved. The more rapid absorption of fentanyl from AD 923 compared withActiq(R) was statistically significant, with substantial plasmaexposure seen within 10 minutes. The median Tmax (time to maximumplasma concentration) for AD 923 was 40 minutes compared with 120minutes for Actiq(R)...

New Studies Evaluating NexiumIn Pediatric GERD To Be Presented At Annual Digestive Disease Week Meeting

...ke other PPIs, esomeprazole may interfere with the absorption ofdrugs where gastric pH is an important determinant ofbioavailability (eg, ketoconazole, iron salts, digoxin).Concomitant administration of esomeprazole may reduce the plasmalevels of atazanavir. Concomitant administration of esomeprazole may reduc...

FDA Announces Results of Investigation Into Illegal Promotion of OxyContin by The Purdue Frederick Company, Inc.

...ycodone," and byrepresenting that "…delayed absorption as provided byOxyContin Tablets is believed to reduce the abuse liability of thedrug." “FDA will not tolerate practices that falsely promote drugproducts and place consumers at health risk,” said MargaretO.K. Glavin, Associate Commiss...

Bema Fentanyl Demonstrates Substantial Transmucosal Delivery In Absolute Bioavailability Study

...ults ofa 12 subject, crossover study comparing the absorption of fentanylfrom both single and multiple BEMA(TM) ...rmacokineticstudy which demonstrated that fentanyl absorption from the BEMA(TM)delivery system was better than that seen with Actiq(R). This studyshowed that the ...

New Data Show Xenical Significantly Reduces Cardiovascular Risk and More Than Doubles Weight Loss Achieved in Overweight and Obese People

...hat workslocally in the gut to prevent dietary fat absorption by around 30%to effectively promote weight loss. The efficacy and safety ofXenical has been proven in an extensive clinical trials programme,with over 100 Phase III/IV trials, in over 30,000 patients. Xenicalis the most extensively studied weight los...

Spectrum Pharmaceuticals Announces Data From Three Oncology Programs Presented at the American Association of Cancer Research Annual Meeting

...g the effect on surgicalwound healing and systemic absorption of EOquin when givenintravesically as a single dose immediately after transurethralresection of bladder tumor (TUR-BT). EOquin in 40mL of instillatewas instilled into the bladder within 6 hours of TUR-BT. After anhour, the bladder was drained and pat...

Nasulin Interim Results to Be Presented at American Diabetes Association Scientific Sessions

... proprietary drug deliverytechnologies enhance the absorption of pharmaceutical compoundsacross various membranes. Bentley manufactures and markets agrowing portfolio of generic and branded generic pharmaceuticals inEurope for the treatment of cardiovascular, gastrointestinal,infectious and central nervous syst...

Novagali Pharma Announces Positive Vekacia Clinical Results From Pivotal Phase III Trial in Vernal Keratoconjunctivitis

...sionenabling an efficient and unmatched-level drug absorption intissues of the eye leading to optimal therapeutic efficacy. Thisproprietary ophthalmic emulsion of Cyclosporine A will be the firsttherapeutic product dedicated to treatment of such a severe ocularcondition. "We achieved a major corporate mileston...

Eurand Announces Positive Phase III Clinical Study Results

...ally significantincrease in the coefficient of fat absorption (CFA) in patientstreated with Zentase. The mean pe...ally significantincrease in the coefficient of fat absorption and coefficient ofnitrogen absorption (CNA) as compared to those receiving a placebo.They also had f...

Scientific Results Presented At ECCMID Demonstrate Well- Differentiated Profile of Basilea's Two Phase III Anti- infective Compounds

...capsules, the prodrugresults in rapid and complete absorption and distribution ofisavuconazole to infected tissues. Basilea successfully completed its phase II trial with both highclinical cures rates and a safety profile comparable to goldstandard fluconazole therapy and with a more flexible dosingschedule. C...

Once Daily, Extended-Release Ropinirole Improves Parkinson's Symptoms in Patients not Optimally Controlled With Levodopa

...n, it has been designed to provide asteady rate of absorption in the body to help reduce blood plasmafluctuations over 24 hours. In the EASE- PD Adjunct Study, REQUIPXL 24-Hour has been shown to be effective in treating both motorand non-motor symptoms of Parkinson's disease as an addition to L-dopa. GlaxoSmith...

Arpida Announces Promising Results of "First-In-Man" Studies With AR-709

...llylow but this could be due to the low dose, poor absorption orextensive metabolism. The studies were conducted at Hammersmith Medicines Research Ltd(London, UK) under MHRA regulatory authorisation and werecoordinated by Xceleron Ltd (York, UK), the exploratory clinicaldevelopment specialist and world leader ...

Preclinical Data on Cytogen's Technology to be Reported at the AACR Annual Meeting

...trointestinal tract, thus facilitating itssystemic absorption into the bloodstream. The binding of these oraldelivery agents to GIT receptors has been confirmed in preclinicalmodels, and successful in vivo delivery ofnanoparticle-encapsulated insulin and leuprolide in animal modelshas been demonstrated. About ...