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Vessels in Medical Technology

OPAXIO(TM) Combined with Alimta(R) Well Tolerated in Dose-Ranging Study of Patients with Advanced Non-Small Cell Lung Cancer

... chemotherapy and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules like ... distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing ...

Paclitaxel Poliglumex (OPAXIO(TM)) Added to Cisplatin and Radiation Produces 45% Pathologic Complete Remissions in Patients With Esophageal Cancer

... chemotherapy and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules like ... distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing ...

New Data Shows AZOR(R) (amlodipine and olmesartan medoxomil) Significantly Improves 24-Hour Ambulatory Blood Pressure

... pressure can cause permanent changes to blood vessels and the heart that may create serious problems ... Angiotensin II is a hormone that causes blood vessels to tighten and narrow. Together the two medicines relax the blood vessels so that blood can flow more easily. Benicar ...

Bayer and Regeneron Extend Development Program for VEGF Trap-Eye to Include Central Retinal Vein Occlusion

... resulting in the growth of abnormal new blood vessels that can cause further vision loss and more ... to edema and the growth of abnormal new blood vessels that are mediated by vascular endothelial growth ... resulting in the growth of new abnormal blood vessels that can cause further vision loss and more ...

Scientists Discover a Role for the Growth Factor TGF-beta in Maintaining Health of Retinal Blood Vessels

... as TGF-beta is essential to the health of blood vessels in the retina and that blocking it can cause ... of the molecules that help to maintain blood vessels in a healthy state," says Patricia D'Amore, PhD, ... team. Capillaries are the smallest blood vessels in the body and the site at which oxygen and ...

The Lancet Publishes Two-Year Results of Abbott's Fully Bioabsorbable Drug Eluting Stent

... Absorbed Within Two Years, Leaving Behind Blood vessels that Appear to Move and Function Similar to Untreated vessels ABBOTT PARK, Ill., March 12 ... device was absorbed, the treated blood vessels appeared to move and function similar to ...

Chemoembolization Improving as Liver Cancer Treatment

... the beads (also called microspheres) to the blood vessels that feed the tumor. The beads are combined with ... embolization is that blocking the tumor feeding vessels in some cases leads to restriction in blood flow ... sizing, which match the small blood vessels that feed the tumors. The larger the particles ...

Late-Breaking Data Highlighting Research Advances in Several Blood Disorders to Be Presented At the American Society of Hematology Annual Meeting

... a.m. "Abnormal function of the cells lining blood vessels may contribute to the complications of sickle ... endothelial dysfunction -- the inability of blood vessels to dilate properly -- in patients with sickle ... (a highly reactive form of oxygen) in blood vessels may decrease levels of tetrahydrobiopterin, ...

Studies Examine Quality of Care for Hospitalized Sickle Cell Disease Patients and Effective Methods for Detecting Risk of Stroke in Children With This Disorder

... (a life-threatening condition affecting the blood vessels in the lungs), organ damage, and blindness. ... due to vaso-occlusion (the blockage of small vessels by sickled cells). One of these severe ... of avascular necrosis (blockage of small vessels in the bone area causing destruction to joints) ...

Reprogrammable Cell Type Depends on a Single Gene to Keep Its Identity

... how during embryogenesis a critical set of vessels called the lymphatic vasculature arises from veins; and how lymphatic vessels can eventually lose their characteristics and acquire features typical of blood vessels and transport blood -- a trick that might, for ...

Exercise Helps Prevent Age-Related Brain Changes in Older Adults

... blood flow and a greater number of small blood vessels in the brain, according to findings presented ... blood flow and MR angiography to depict blood vessels in the brain. Using a novel method of ... were able to make 3-D models of the blood vessels and examine them for shape and size. They then ...

Taxus Atlas Studies Reinforce Safety and Efficacy of Boston Scientific's Next-Generation Taxus Liberte Stent

... or improved safety outcomes in small vessels compared to the TAXUS Express Stent," said Dr. ... Coronary Stent System for use in vessels as small as 2.25 mm in diameter and the TAXUS Liberte Stent for coronary vessels 2.5 mm to 4.0 mm in diameter. The TAXUS Liberte ....

Boston Scientific to Release Broad Range of Clinical Trial Data on the Performance of TAXUS(R) Coronary Stent Systems at TCT 2008

... Stenting trials and two-year ATLAS data on small vessels and long lesions (TAXUS Liberte Stent). "We are ... of TAXUS Liberte vs. TAXUS Express in Small vessels and Long Lesions in the TAXUS ATLAS SMALL VESSEL ... only DES approved by the FDA for use in vessels as small as 2.25 mm in diameter. The safety and ...

Complete Study Results Comparing CTI's OPAXIO(TM) With Gemcitabine or Vinorelbine in Performance Status (PS 2) NSCLC Patients Published in Journal of Thoracic Oncology

... active drug and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules like ... to tumors due to their leaky blood vessels and trapped in the tumor bed allowing ...

Bayer and Regeneron Dose First Patient in Second Phase 3 Study for VEGF Trap-Eye in Wet Age-Related Macular Degeneration

... vision loss. It occurs when abnormal blood vessels in the eye leak fluid and blood into the macula, ... role is to trigger the formation of new blood vessels (angiogenesis) to support the growth of the ... the abnormal growth and fragility of new blood vessels in the eye, which lead to the development of wet ...

European Regulatory Agency Accepts Cell Therapeutics, Inc.'s Marketing Authorization Application for XYOTAX(TM) for Lung Cancer for Review

... chemotherapy and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules like ... distributed to tumors due to their leaky blood vessels and trapped in the tumor bed ...

Study Finds Taxus(R) Drug-Eluting Stent Beneficial in Treatment of Large Vessels

... over BMS even in the treatment of large vessels (greater than 3.5 mm), which typically ... rates in both large and small diameter vessels compared to BMS. Although the absolute magnitude ... cardiologists to choose BMS over DES in vessels larger than 3.5mm. However, since ...

CardioMind Launches First-in-Human Trial of Small Vessel, Drug-Eluting Stent

... of stenting in small vessels, branch vessels and other difficult-to-access vessels. It ... interventionalists to treat very small blood vessels of 2.75 mm-diameter and less. Such vessels, often ... both stent safety and efficacy in such vessels and to extend the range ...

Anti-Cancer Drug CYT997 Update

... of action shutting down established blood vessels that supply the tumor with nutrients and oxygen ... Experimental therapies which attack GBM blood vessels have shown promise in treating this condition ... specialized MRI to detect changes in tumor blood vessels as a marker for CYT997 activity. Interim data ...

Cell Therapeutics, Inc. (CTI) Submits European Marketing Authorization Application for XYOTAX(TM)

... chemotherapy and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules like ... distributed to tumors due to their leaky blood vessels and trapped in the tumor bed ...

Do-It-Yourself Cardiac Bypass Surgery: All You Need is Walking Shoes

... the body responds by trying to bulk up tiny blood vessels in the heart. As these so-called ... been trying for years to nudge collateral blood vessels to develop and prosper, but without great ... 2008 issue. Growing new collateral blood vessels can ease chest pain (angina), limit heart attack ...

Ellex 2RT Study Demonstrates Clinical Efficacy in Treatment of Diabetic Macular Edema

... wet form is caused by growth of abnormal blood vessels under the macula, also known as choroidal neovascularization (CNV) or ocular angiogenesis. These vessels are of poor quality and tend to leak fluid ... adults. It is caused by changes in the blood vessels of the retina. The U.S. Food and Drug ...

Patient Enrollment Complete in First Trial to Compare Physiologic Guidance vs. Angiographic Guidance of Stent Deployment in Patients with Multivessel Disease

... in at least two of the three major cardiac vessels have narrowings of greater than or equal to ... stenting, according to the investigator. -- The vessels are large enough to accommodate drug-eluting ... flow reserve (FFR) measured in diseased vessels with a coronary pressure wire using a ...

Boston Scientific to Release Broad Range of Clinical Trial Data Reinforcing Safety and Efficacy of Taxus(R) Coronary Stent Systems at TCT 2007

... Stent, and nine- month data on small vessels and long lesions from the ATLAS trial, which ... release at this time. -- TAXUS ATLAS Small vessels and Long Lesions studies. Nine-month data ... with the TAXUS Liberte 2.25 mm stent in small vessels (from the TAXUS ATLAS Small Vessel study) and ...

Peripheral Arterial Disease to be Treated With New Medicated Stent in Trial at Montefiore

... The disease restricts circulation in blood vessels that lead from the heart to other areas of the ... evaluation of a drug- eluting stent in blood vessels outside the heart," said Evan Lipsitz, MD, chief ... "Combining a stent designed to hold blood vessels open to allow blood to flow freely through the ...

Cell Therapeutics, Inc. (CTI) Supports Panel Discussion on Women and Lung Cancer on Capitol Hill

... chemotherapy and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules ... distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing ...

Cell Therapeutics, Inc. (CTI) Sponsors Panel Discussion on Women and Lung Cancer on Capitol Hill

... chemotherapy and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules ... distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing ...

Study Results Show That Minimally Invasive Therapy is Successful for Over Two-Thirds of Stroke Patients Treated Outside the Standard Eight-Hour Window

... inserted through a catheter or narrow tube that is threaded up through the vessels directly to the problem site to dispel the clot) could potentially be ... whose first angiography (a diagnostic test that infuses the blood vessels with dye in order to clearly visualize the vessel structures) confirming a ...

FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent

... an enzyme produced by the kidneys that starts a process that makes blood vessels narrow and, when inappropriately activated, may lead to high blood pressure. Tekturna reduces renin activity and helps blood vessels relax and widen so blood pressure is lowered. Diuretics work to lower ...

Unique Cardiovascular Treatment Readied for Global Market: Proprietary Paccocath(R) Technology is the Only Drug Eluting Balloon with Clinical Data

... treatments may have limited effectiveness since, for most patients, the vessels often re-occlude within a year after treatment. The Paccocath ... using the Paccocath technology during an angioplasty procedure keeps the vessels open wider over time compared to standard angioplasty and published ...

Glycerin Proven to Improve Bruising and Swelling Caused By Trauma to Skin

... It is a thick, water-soluble liquid. Bruises occur when capillary blood vessels break and blood and fluids pool underneath the skin. Glycerin's hydrating properties enable the body to seal off the broken capillaries and blood vessels caused by trauma to the skin and help prevent the pooling of blood and ...

New Data Shows Blood Pressure Reduction Therapy with BENICAR(R) and BENICAR HCT(R) Effectively Reduces Blood Pressure in Elderly Patients to Target Blood Pressure

... percent). High blood pressure can cause permanent changes to blood vessels and the heart that may create serious problems elsewhere in the body.(4) ... lower blood pressure by blocking the angiotensin II receptor on the blood vessels and antagonizing the release of the hormone which causes salt retention ...

Data Presented at AACR Annual Meeting Show Anti-Tumor Activity of Peregrine's Fully Human Anti-PS Antibody in Prostate Cancer Model

... becomes exposed on the external surface of the cells that line the blood vessels of tumors (the tumor vascular endothelium), creating a specific target for ... therapy or docetaxel substantially increased the percentage of tumor blood vessels with PGN635 binding. The researchers also reported that in a mouse ...

Studies Presented at AACR Annual Meeting Highlight Multiple Immunomodulatory Mechanisms of Peregrine's PS-Targeting Antibodies

... insight into the mechanisms that act to selectively destroy the blood vessels supporting tumor growth and spread and also to reverse the ability of ... but which becomes exposed on the outside of the cells that line the blood vessels of tumors, creating a specific target for anti-cancer treatments. By ...

Astrocytes Help Separate Man From Mouse

... concerns the end feet of protoplasmic astrocytes, which wrap around blood vessels throughout the brain and are thought to play a role in the brain's blood flow. In humans, these end feet cover the walls of blood vessels much more completely than they do in mice and rats, possibly playing a ...

ThromboGenics Completes Patient Enrolment for Phase II Trial of Microplasmin for the Treatment of Diabetic Macular Edema (MIVI II DME)

... patients with diabetic retinopathy, due to a leakage of fluid from blood vessels within the macula. The only approved treatment for patients with DME is ... retina has been associated with greatly reducing the growth of new blood vessels (neovascularization) on the retina, which plays a fundamental role in the ...

Diabetes Patients with High Triglycerides and Low HDL Cholesterol Get the Most Benefit From Fenofibrate Treatment: New Data From the FIELD Study

... need for laser treatment in patients with diabetic disease in the small vessels of the eyes. It also reduces the risk of amputations resulting from disease in the small vessels of the limbs. FIELD (5), a large international multicentre trial in ...

Study Shows Leconotide, an Investigative Calcium Channel Blocker, Has Potential as a Selective, Efficacious, Non-Opioid Pain Treatment

... cell such as force of contraction of a muscle cell in the heart or blood vessels or rate of electrical firing or production of chemical messengers in nerve ... can be selective to bind just with one type (e.g. heart and blood vessels to lower blood pressure). Calcium channels in nerve cells are involved ...

Synvista Therapeutics Announces Published Data Demonstrating Elevation of Carboxymethyl-Lysine (CML) Is Associated with Decline in Renal Function and Arterial Stiffness in Older Adults

... link, which makes them less flexible. When formed in the heart and blood vessels (the cardiovascular system), cross linked collagen induces stiffness, a loss of adaptability and decreased reactivity which makes the heart and blood vessels act less effectively and may increase the risk of cardiovascular ...

Abbott's XIENCE V(TM) Drug Eluting Stent Outperforms TAXUS(R) in Key Efficacy and Safety Endpoints Out to Two Years

... years across multiple subgroups examined, including patients with small vessels and multi-vessel patients. In diabetic patients, the analysis showed there ... has been shown to inhibit in-stent neointimal growth in the coronary vessels following stent implantation, due to its anti-proliferative properties. ...
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(Date:4/23/2014)... announced Sophie Martin of the University of Lausanne, Switzerland, ... The award acknowledges her work to understand the molecular ... cell. , Martin has been working for the past ... way in which the spatial organization of cells contributes ... 11 years, she has been using fission yeast, which ...
(Date:4/23/2014)... new study by a University of Exeter researcher has ... of wild camels thriving in Australia,s remote outback have ... scale. , Sarah Crowley, of the Environment and Sustainability ... the history of the camel in Australia, from their ... to their current status as unwelcome "invader." , The ...
(Date:4/23/2014)... a technique used to read quickly. It involves ... non-essential words and/ or sentences. Similarly to humans, ... quickly "read" genetic information. Genes that need to ... smaller the encoding message, the easier it will ... Instituto Gulbenkian de Cincia (IGC, Portugal) and Centre ...
Breaking Biology News(10 mins):EMBO Gold Medal 2014 awarded to Sophie Martin 2How Australia got the hump with 1 million feral camels 2How Australia got the hump with 1 million feral camels 3Cell division speed influences gene architecture 2
(Date:4/23/2014)... Parents and physicians concerned about an increase in adolescents, ... breathe a sigh of relief. According to a new ... worth of data from states with and without medical ... increased use among adolescents. The study is published online ... Adolescent Health . , "Any time a state ...
(Date:4/23/2014)... of endogenous neural precursor cells cannot alone compensate ... the perspective of neural plasticity, Dr. Yun Xiang ... observed the effects of functional electrical stimulation treatment ... of basic fibroblast growth factor and epidermal growth ... side. The researchers found that functional electrical stimulation ...
(Date:4/22/2014)... A recently FDA-approved device has been shown to reduce ... as 50 percent. When coupled with an innovative electrode ... device facilitated the complete elimination of seizures in nearly ... decade-long clinical trials. , That,s good news for a ... U.S. living with epilepsy whose seizures can,t be controlled ...
(Date:4/22/2014)... are small cell lung cancers (SCLC), which grow ... researchers at Virginia Commonwealth University Massey Cancer Center ... to this resistance that may lead to improved ... B-cell lymphoma 2 (Bcl-2) family proteins, which are ... function, this family of proteins can trigger a ...
(Date:4/22/2014)... scientists have found a way to block abnormal cholesterol ... atherosclerosis, the main cause of heart attacks and strokes ... condition develops when fat builds inside blood vessels over ... reducing their ability to feed oxygen-rich blood to the ... of experiments, described April 7 in the journal ...
Breaking Medicine News(10 mins):Health News:RI Hospital physician: Legalizing medical marijuana doesn't increase use among adolescents 2Health News:Newly approved brain stimulator offers hope for individuals with uncontrolled epilepsy 2Health News:Scientists pinpoint protein that could improve small cell lung cancer therapies 2Health News:Scientists alter fat metabolism in animals to prevent most common type of heart disease 2Health News:Scientists alter fat metabolism in animals to prevent most common type of heart disease 3Health News:Scientists alter fat metabolism in animals to prevent most common type of heart disease 4
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