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Transplant in Medical Technology

UPCI Joins ExCell Research Study Using Stem Cells for Leukemia and Lymphoma Patients

... director of UPCI's Hematopoietic Stem Cell transplant Program. "Using umbilical cord blood stem cells instead of a traditional bone marrow transplant opens tremendous treatment possibilities for ... than half the number of patients in need of a transplant can't find matching bone marrow donors. Cord ...

WORLD'S First Robotic Assisted Kidney Transplant Performed at Saint Barnabas Medical Center

... LIVINGSTON, N.J., June 4 /PRNewswire/ -- transplant surgeon, Stuart R. Geffner, M.D., Director of Kidney and Pancreas transplant Surgery, Saint Barnabas Health Care System Renal and Pancreas transplant Division, is the first in the world to use the ...

PARI Pharma Reports Successful Phase Ib Clinical Results for Inhaled Liposomal Cyclosporine A and Gains FDA Orphan Drug Designation for the Prevention and Treatment of Bronchiolitis Obliterans

... "The long-term survival rate for lung transplant patients could be greatly improved through an ... Phase Ib clinical trial for L-CsA studied 12 lung transplant recipients, where five patients had double lung ... comparison, oral CsA (Neoral(R)) therapy in lung transplant patients leads to highly variable C(max) and ...

IMPACT Study Showed Longer Valcyte(R) (valganciclovir hydrochloride tablets) Treatment Demonstrated Better Protection Against Cytomegalovirus (CMV) Disease One Year Post-Transplant

... CMV is the most serious viral infection affecting transplant patients BOSTON, June 1 /PRNewswire/ -- ... the first time today at the ninth annual American transplant Congress 2009 (ATC) demonstrate that doubling the ... of CMV disease by 56% in high-risk kidney transplant patients within the first year post-transplant. ...

Three Independent Studies Include the ImmuKnow(R) Assay to Manage and Optimize Immunosuppression Therapy in Transplant Patients

... studies will be presented during the American transplant Congress in Boston, MA May 30 - June 3, 2009 ... Medical Center in Valhalla, NY examined liver transplant recipients to determine whether the use of the ... in this study, "Using ImmuKnow in liver transplant recipients may help minimize renal injury by ...

Living Donor Kidney Transplants Using Alemtuzumab Pre-Conditioning and Tacrolimus Monotherapy: Long-Term Safety and Efficacy

... studies will be presented during the American transplant Congress in Boston , MA May 30 - June ... studies presented by researchers from the Starzl transplant Institute at the University of Pittsburgh ... and is increasingly being adopted at organ transplant centers throughout the United States and abroad. ...

Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support

... Cell Modulator Administered in Dual Cord Blood transplant for Hematologic Malignancy LA JOLLA, Calif., ... the standard course of dual umbilical cord blood transplant in adult patients with hematologic malignancies, ... receiving a bone marrow or peripheral blood transplant must find a donor that matches at least five of ...

Terumo Heart, Inc. Reaches Clinical Milestone as the 100th Patient Worldwide Receives the DuraHeart(TM) Left Ventricular Assist System

... in helping to sustain patients awaiting heart transplant who are at risk of death due to end-stage left ... technology to our patients awaiting heart transplant who are at risk of death due to end-stage left ... annually, but less than 3,000 will receive a transplant each year. A large number of people who suffer ...

An Independent Study Reports on the Utility of ImmuKnow(R), the Cylex(TM) Immune Cell Function Assay, for Monitoring Heart Transplant Recipients

... Geffen School of Medicine followed 337 cardiac transplant patients with ImmuKnow to determine whether ... for individualizing immunosuppression in heart transplant recipients." "This study expands our ... function assay in effective management of heart transplant recipients in the post-transplant setting," ...

David Feldman, M.D. Appointed Co-Principal Investigator of DuraHeart(TM) Left Ventricular Assist System U.S. Clinical Trial

... joins Dr. Francis Pagani, Director of the Heart transplant and Center for Circulatory Support at University ... Transplantation and Director of Heart Failure and transplant Fellowship Program at The Ohio State University ... , including the Heart Lung Research Institute, transplant Consortium and Congestive Heart Failure ...

Terumo Heart, Inc. Reports Clinical Progress in the DuraHeart(TM) U.S. Pivotal Trial as NewYork-Presbyterian Hospital/Columbia University Medical Center Implants First Patient

... in helping to sustain patients awaiting heart transplant who are at risk of death due to end-state left ... meaningful quality of life while awaiting a heart transplant or ultimately as a long-term solution to a ... annually, but less than 4,000 will receive a transplant each year. A large number of people who suffer ...

Bone Biologics Announces Significant Milestone for Spinal Fusion Surgery Using Recombinant Protein and Demineralized Bone Matrix

... matrix (scaffold) produced by the Musculoskeletal transplant Foundation (MTF). "The Musculoskeletal transplant Foundation is a world leader in tissue research ... use in humans. About The Musculoskeletal transplant Foundation MTF is a non-profit service ...

Fifth U.S. Hand Transplant Patient Heads Home to NY

... -- The United States' fifth hand transplant recipient, Jan "Erik" Hondusky, is heading back ... UofL hand surgeons performed the Hondusky's hand transplant at Louisville's Jewish Hospital Hand Care Center ... to perform daily living activities before the transplant procedure. Lead ...

ViroPharma Announces Discontinuation of Maribavir Phase 3 Study in Liver Transplant Patients

... against cytomegalovirus (CMV) disease in liver transplant patients has been discontinued, and that all ... of the Phase 3 study of maribavir in stem cell transplant patients, and the recommendation from our ... to standard CMV treatment practices at the transplant center. The primary efficacy endpoint was ...

Quark Pharmaceuticals Announces Dosing of the First Patient in Phase I/II Clinical Trial for Systemically Delivered siRNA Drug Candidate for Delayed Graft Function

... DGF is expected to enroll up to 204 adult kidney transplant recipients. The first part of the study is a ... single intravenous injection of QPI-1002 in renal transplant patients at high risk to develop DGF. The second ... to offer therapeutic benefit to adult kidney transplant patients at high risk for developing DGF. The ...

Cleveland Clinic Surgeons Perform Nation's First Near-Total Face Transplant

... recently performed the first near-total face transplant in the United States. In a 22-hour ... This is the largest and most complex face transplant in the world, integrating different functional ... difference in this patient's life." The transplant team was led by Maria Siemionow, M.D., Ph.D., ...

Research Explores the Effects of Stem Cell Source and Patient Age on Stem Cell Transplantation Outcomes

... a donor). Effect of Stem Cell Source on transplant Outcomes in Adults With Acute Leukemia: A ... source of stem cells for patients who need a transplant but cannot find a matched adult donor. The ... group of 17 patients underwent an identical transplant regimen, but received two non-cultured cord blood ...

Novel Therapeutic Approaches May Transform Treatment and Improve Patient Outcomes in Several Platelet Disorders

... tumor (seven patients), autologous stem cell transplant (429 patients), or an allogeneic stem cell transplant (523 patients). Patients were prophylactically ... high-dose chemotherapy and autologous stem cell transplant can be prevented through an experimental ...

Kleinert Kutz Hand Surgeons Perform Fifth U.S. Hand Transplant in Record Time at Jewish Hospital Hand Care Center

... hand surgeons performed the fifth U.S. hand transplant on Messina, New York resident, Jan "Erik" ... and Joseph Buell, M.D., director, Jewish Hospital transplant Center, manage the immunosuppressive therapy for all five hand transplant patients performed at Jewish Hospital. ...

Vical Completes Enrollment and Reports Positive Interim Data in CMV Vaccine Phase 2 Trial

... and disease in immunosuppressed stem cell transplant recipients. An interim analysis of immunogenicity data for the first 33 transplant recipients in the recipient-only arm of the study ... "These patients are highly immunosuppressed after transplant and, due to pre-existing infection, are at risk ...

Cylex Announces Plan for Multi-Center Trial of ImmuKnow(R) Assay in South Korea

... on studies of immunosuppression in kidney transplant patients and role of cell-mediated immunity ... the effectiveness of the ImmuKnow assay in transplant populations of different ethnicities by working ... ages of 15 and 60 who undergo an initial kidney transplant and who are randomly assigned to receive ...

Pediatric Heart Transplants at Montefiore Approved by NY State Department of Health

... Key to addition of the new pediatric heart transplant capabilities was the recruitment of nationally ... Noninvasive Imaging. "The new pediatric heart transplant program at CHAM and its acclaimed cardiology team ... and Montefiore medicine." "The pediatric heart transplant program and the addition of Dr. Hsu and her team ...

New Data Support Role for Monitoring of Cell-Mediated Immunity in Adult Patients Following Renal Transplantation

... study of adult kidney transplant patients COLUMBIA, Md., Aug. 21 /PRNewswire/ -- ... group of stable transplant patients, and infected transplant patients, with a statistically significant ... levels for these three groups: -- Infected transplant group (n = 24): mean ATP level = 197 +/- 114 ...

New Data Support Earlier Suggested Guidance for Levels of Cell-Mediated Immunity in Pediatric Liver Transplant Patients

... study of pediatric liver transplant patients COLUMBIA, Md., Aug. 21 /PRNewswire/ -- ... had undergone liver transplantation. In adult transplant patients, cell-mediated immunity as measured ... cell-mediated immunity in pediatric transplant patients, and in liver transplant patients in ...

Precise Low-Dose Drug Monitoring Essential for Long-Term Kidney Transplant Success

... ARCHITECT Tacrolimus Assay, Only Automated transplant Monitoring Test that Meets International ... (AACC) annual meeting. The current thinking in transplant medicine favors reducing doses of tacrolimus and ... Abbott Diagnostics. "Unfortunately, most kidney transplant patients will go back on dialysis in eight to ten ...

Promise of Vical's CMV Vaccine Noted by Independent Experts

... CMV infection continues to be a problem in the transplant setting. CMV immunity appears to play a critical ... in the management of CMV infection and disease in transplant patients. Clinical trials are ongoing to test ... healthcare problem of CMV reactivation for transplant patients, and could eventually be useful in ...

CellCept(R) and a Reduced Level of CNI Shows Trend Towards Preservation of Kidney Function Versus a Standard-Dose CNI

... was presented today at the American transplant Congress (ATC). The study results showed that ... immunosuppression in patients who develop PML. In transplant patients, physicians should also consider the ... (ANC) cardiac, and up to 3.6% of hepatic transplant patients receiving CellCept 3 g daily. ...

University of Miami Team Confirms Value of Monitoring Cell-Mediated Immunity Pre- and Post-Transplant in Management of Kidney Transplant Recipients

... New data presented at annual American transplant Congress in Toronto MIAMI, June 2 /PRNewswire/ ... of monitoring cell- mediated immunity (CMI) post transplant in recipients of kidney transplants using a ... in the management of post kidney transplant recipients," will be presented on June 2 at the ...

Final Results of the CellCept(R) Spare the Nephron (STN) Study Show Maintenance Therapy is Associated with Improved Renal Function

... (ATC) in Toronto. The STN Trial in kidney transplant recipients examines ways to prevent rejection without damaging kidneys. As transplant patients are living longer, studies suggest that ... The STN trials were conducted at more than 35 transplant centers in the United States and Canada. "The ...

Multiple Clinical Trials of VELCADE(R) (Bortezomib) for Injection Based Therapies Demonstrate High Complete Remission Rates in Patients with Newly Diagnosed Multiple Myeloma

... demonstrated a CR rate of 46 percent prior to transplant and 72 percent post-transplant -- VELCADE, DOXIL and dexamethasone (PAD or VcDD) prior to transplant showed a CR rate of 21 percent which ... planned with a goal of proceeding on to stem cell transplant (SCT). Results were presented by Craig ...

ViroPharma Announces Completion of Enrollment in Phase 3 Study of Maribavir in Stem Cell Transplant Patients

... - Phase 3 Study in 681 Stem Cell transplant Patients Represents First Pivotal Study on a New Antiviral CMV Therapy in Stem Cell transplant in Over a Decade - - ... pivotal Phase 3 study of maribavir in stem cell transplant patients. This international Phase 3 study is ...

Lung Transplants in Cystic Fibrosis Patients With Life-Threatening Bacteria Sparks Debate at ISHLT Meeting

... unique challenges in achieving excellent lung transplant outcomes in patients with CF. A highlight of ... in general, the best outcomes, and a successful transplant can mean a significant increase in lifespan and ... presence does not influence the outcomes after transplant in CF patients. However in 5 percent of ...

Prospective Microbial Analysis of Bronchoalveolar Lavage Fluids with Immune Function Testing Can Distinguish Between Fungal Colonization and Fungal Disease In Lung Transplant Recipients

... Data from 150 lung transplant patients demonstrates potential to improve ... Data were collected prospectively from 170 lung transplant recipients at UPMC between 2003 and 2006. These ... higher than the value in the six transplant patients with fungal disease (78 ng/mL ATP; p < ....

Research Presented at ISHLT Shows Promise of Addressing Critical Organ Shortage and Better Organ Preservation

... Although thousands of patients are on lung transplant waiting lists around the world, only a small ... for Heart Transplantation, Ayyaz Ali, F.R.C.S., transplant Fellow from Papworth, will provide a report ... a larger portion of donor hearts being used to transplant patients who need them (Abstract #143). ...

Biomarkers May Reduce the Need for Biopsies and Offer Personalized Care for Heart and Lung Transplant Patients

... to reduce the need for biopsies and personalize transplant patient care. Non-invasive testing using ... or urine samples called biomarkers could offer transplant patients personalized care and medication and may ... for Probing Proteomic Biomarkers in Plasma of transplant Patients. Finally, Dr. Ralph Weissleder from ...

Independent Studies Report on Possible Roles for Cylex's Immune Cell Function Assay in Monitoring of Heart and Lung Transplant Recipients

... colonization and fungal disease in lung transplant recipients" (S. Husain, J. Pilewski, K. ... therapeutic drug monitoring in selected heart transplant patients, a case series" (T. Ben Gal, V. ... cell function assay in pediatric heart transplant patients" (J. W. Rossano, S. W. Denfield, E. O. ...

Mayo Clinic Proceedings Contributors Discuss Impact of Donor Organ Allocation System

... Minn., Feb. 6 /PRNewswire-USNewswire/ -- Liver transplant is a life saving treatment option for people with ... available donor organs to the most critically-ill transplant candidates, UNOS adopted a scoring system called ... for donor organs. "Early referral to a liver transplant center no longer provides an advantage for organ ...

Organ Donor Shortage Remains Obstacle for Would-Be Transplant Patients Despite Better Medicine

... worldwide who would benefit from an organ transplant and the number of organs available, a gap that is impacting transplant medicine markets, according to a new market research report from Kalorama Information, Organ transplant Immunosuppressive Markets. In the US, over ...

Northwestern Memorial Transplant Program Initiates New Study

... Study seeks to wean certain kidney transplant recipients off anti-rejection drugs following ... Jan. 22 /PRNewswire-USNewswire/ -- After a transplant surgery, anti-rejection drugs for the organ ... subjects in a new research study that seeks to transplant stem cells from a kidney donor's bone marrow into ...

Raydiance Collaborates With Rutgers University and Nation's Largest Tissue Bank to Develop Innovative Tissue Processing Approaches

... and institutes. About The Musculoskeletal transplant Foundation The Musculoskeletal transplant Foundation is the nation's largest full service ... 616 cblesch@ur.rutgers.edu Musculoskeletal transplant Foundation Megan Murphy Schwab 732-661-2574 ...
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