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Transfer in Medical Technology

Novel Vaccine Approach Offers Hope in Fight Against HIV

... --Gene transfer Technology May Lead to an HIV Vaccine-- ... followed by vaccine developers. By using gene transfer technology that produces molecules that block ... Johnson et al, "Vector-mediated gene transfer engenders long-lived neutralizing activity and ...

New Study Proves Multiple Births From IVF Can Be Avoided

... Center Proves that elective Single Embryo transfer is Effective in Reducing Multiple Births. ... website, proved that elective Single Embryo transfer (eSET) for In Vitro Fertilization (IVF) can ... rates. It also showed that patients prefer to transfer one embryo when freed from financial pressures ...

Trana Discovery and Southern Research Institute Announce the First RNA-RNA High Throughput Drug Screening Assay Platform for HIV Antivirals

... a novel mechanism of action -- the inhibition of transfer RNA (tRNA). This technology has the potential ... antiretroviral drugs -- the disruption of human transfer RNA (tRNA) use by the virus during ... a novel mechanism of action -- the inhibition of transfer RNA (tRNA). The company enables exclusive rights ...

Prospective Clinical Advantages of Trabecular Metal(TM) Technology Highlighted in Comparative Study

... the elasticity (low stiffness) of Trabecular Metal material may induce a transfer of stresses to the periacetabular bone that more closely replicates the ... of this porous metal --similar to cancellous bone--were better able to transfer physiological stresses, theoretically decreasing the detrimental effects ...

CRi Oosight(TM) Instrument Crucial in IVF Breakthrough Demonstrating a Correlation Between Non-Invasive Egg Metrics and Pregnancy

... predictive criteria for the selection of the best embryo for single-embryo transfer remain elusive, CRi's Oosight instrument provides a useful, non-invasive ... Oosight system. Such data are imperative if we are to make single-embryo transfer a reality, thereby greatly reducing the risks associated with multiple ...

Celladon Provides MYDICAR(R) Program Update of First-In-Human Trial for Advanced Heart Failure at American Society of Gene Therapy Annual Meeting

... dysfunction, together with the evolution of safe and efficient gene transfer technology, has placed gene-based therapy for heart failure within reach ... are the product of decades of research focused on the safety of gene transfer agents, and are derived from components of a non-replicating, ...

One Step Closer: Novel Opioid Receptor Compound in Phase I Clinical Trials

... under The Rensselaer Plan in the areas of biotechnology and technology transfer that demonstrates Rensselaer's unique strength in its ability to translate ... executive director of the Office of Intellectual Property, Technology transfer and New Ventures at Rensselaer. "Most importantly, this is a testament to ...

BARC Central Laboratory Joins Alzheimer's Association Research Roundtable

... - Global Laboratory's Technology transfer Expertise to Support Biomarker Translational Research - NEW YORK, ... including molecular diagnostics and genomics, and serves as a technology transfer channel by developing and clinically validating new laboratory tests on a ...

ThromboGenics and BioInvent Receive Technology Transfer Success Fee From Roche for the Novel Anti-Cancer Antibody, TB-403 (Anti-PIGF)

... AB (OMXS:BINV) announce today that they have received a technology transfer success fee of EUR5 million from Roche under the terms of their strategic ... antibody, TB-403. The payment has been triggered by the successful transfer and implementation of technology and process development to Roche in ...

Perceptive Informatics Improves Clinical Trial Management With Enhanced TrialWorks(R) Solution

... information Additionally, a new web interface for the Universal Data transfer Tool, which can be used in conjunction with the TrialWorks solution, provides a more streamlined transfer of patient and visit data as well as Case Report Form (CRF) status from ...

Encouraging Gene Therapy Results in Genetic Form of Blindness

... journal published monthly in print and online that presents reports on the transfer and expression of genes in mammals, including humans. Related topics ... as well as ethical, legal, and regulatory issues related to the gene transfer in humans. Tables of contents and a free sample issue may be viewed online ...

Previous Claims of siRNA Therapeutic Effects Called into Question by Report in 'Human Gene Therapy'

... journal published monthly in print and online that presents reports on the transfer and expression of genes in mammals, including humans. Related topics ... as well as ethical, legal, and regulatory issues related to the gene transfer in humans. Tables of contents and a free sample issue may be viewed online ...

Gene Therapy Slows Progression of Fatal Neurodegenerative Disease in Children

... journal published monthly in print and online that presents reports on the transfer and expression of genes in mammals, including humans. Related topics ... as well as ethical, legal, and regulatory issues related to the gene transfer in humans. Tables of contents and a free sample issue may be viewed ....

Is PCI Safe, Effective After Clot-Busters for Heart Attack?

... a clot-busting drug. Patients were then randomly assigned to urgent transfer for PCI within six hours, or to standard therapy, consisting of observation for 60 to 90 minutes, with transfer for PCI only in the case of continuing chest pain or other evidence ...

St. Jude Finds Signaling System That Halts the Growth of a Childhood Brain Cancer

... failed to develop cerebella. The St. Jude team also performed gene transfer experiments in mice to test BMPs as a possible medulloblastoma treatment. ... scientists inserted the BMP gene into the cancer cells and showed that the transfer not only halted tumor growth, but induced the cancer cells to change into ...

Protalix BioTherapeutics Extends Research Agreement With Yissum Based on Promising Acetylcholinesterase Program Results in Animal Study

... About Yissum Yissum (http://www.yissum.co.il ) -- the technology transfer company of the Hebrew University of Jerusalem -- was founded in 1964 to ... technologies licensed out by Yissum. Ranked among the top technology transfer companies in the world, Yissum has registered 6,000 patents covering 1,600 ...

European Division of Global Top 20 Pharmaceutical Company Awards Phase III Trial to DATATRAK

... integrated technologies. DATATRAK's eClinical((TM)) software suite can be deployed worldwide through an ASP offering or in a licensed Enterprise transfer model that fully empowers its clients. The DATATRAK software suite and its earlier versions have successfully supported hundreds of international ...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... College of Wisconsin. "This study demonstrates that ZFN technology bypasses the current need to conduct cumbersome experiments involving nuclear transfer (cloning) or embryonic stem cells and allows rapid creation of new animal models." In the study published in Science titled "Knockout Rats ...

Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM)

... linked to the achievement of future clinical, regulatory, and commercial milestones. In addition, Bioniche will manufacture the product and receive a transfer price for supply. "We are excited about the opportunity to expand our portfolio in bladder cancer treatment and enhance our late stage ...

CEL-SCI to Present Data from Multikine Clinical Trials at National Institutes of Health (NIH), National Cancer Institute (NCI) Seminar Series

... outcome in these patients. Dr. Talor will also discuss the objectives of the collaborative study between the NIH, NCI under a current Material transfer Agreement. This work is aimed at elucidating the tumor microenvironment changes, at the molecular level, brought about by Multikine treatment of ...

New Data Supports Significant Economic and Clinical Value of MENOPUR(R) in IVF

... offered a superior cost-effectiveness in producing live-births over rFSH in women undergoing conventional IVF and, when available, frozen embryo transfer cycles.[1] Since this study attempts to realistically model the actual situation in patients undergoing infertility management, it is believed that ...

Blanchette Rockefeller Neurosciences Institute and Inverness Medical Innovations to Develop Commercial Test to Detect Early Alzheimer's Disease

... is the world's only non-profit institute dedicated to the study of both human memory and diseases of memory. Its primary mission is to accelerate the transfer of neurological discoveries from the lab to the doctor's office where it can benefit patients who suffer from neurological and psychiatric diseases. ...

Celladon Corporation Announces Presentation of First-in-Human Gene Transfer to Treat Heart Failure at the 12th Annual Meeting of the American Society of Gene Therapy

... expenditures. Recent advances in understanding the molecular basis of myocardial dysfunction, together with the evolution of safe and efficient gene transfer technology, have placed heart failure within reach of gene-based therapy. A Phase 1/2 clinical trial of dose escalation of MYDICAR administered ...

Aching Back? Cholesterol Medication Might Help

... spine surgery and extracting cells from that tissue for cultivation in vitro (a controlled environment outside of a living organism). They then transfer the cells back into the patient. Shu-Hua Yang, MD, PhD, is part of a Taiwanese research team that has discovered that Lovastatin, a ...

deCODE Receives California Clinical Laboratory License

... uncertainties include, among others, those relating to our ability to obtain financing and to form collaborative relationships, the effects of the transfer of our common stock from the Nasdaq Global Market to the Nasdaq Capital Market and the potential delisting of our common stock from the Nasdaq ...

deCODE Breakthrough in Thyroid Cancer May Enable More Targeted Risk Assessment and Earlier Intervention

... uncertainties include, among others, those relating to our ability to obtain financing and to form collaborative relationships, the effects of the transfer of our common stock from the Nasdaq Global Market to the Nasdaq Capital Market and the potential delisting of our common stock from the Nasdaq ...

Heavy Marijuana Use May Damage Developing Brain in Teens, Young Adults

... connections among the frontal, parietal and temporal regions of the brain," said Ashtari. "Abnormal white matter development could slow information transfer in the brain and affect cognitive functions." Ashtari added that the findings are preliminary. Among other limitations of the study, such as a ...

Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs

... The paper is available free online at www.liebertpub.com/clo . Since the cloning of Dolly the Sheep over a decade ago, somatic cell nuclear transfer (SCNT) has been considered a promising way to generate personalized stem cells to repair the body without fear of tissue rejection. Due to the ...

Duska Therapeutics Completes Corporate Name Change to Cordex Pharma

... LP of Bala Cynwyd, PA, as its independent auditors for the year ending December 31, 2008. Cordex also appointed DirectTransfer, LLC as its stock transfer agent, effective immediately. About Cordex Pharma, Inc. Cordex is a specialty pharmaceutical company that develops new cardiovascular ...

Phico Therapeutics Receives GBP1 Million Award From the Wellcome Trust to Take Anti-MRSA Nasal Product Through Early Clinical Trials

... us to conduct phase I and II clinical trials with results expected Q3 2009 and Q3 2010 respectively." Dr Ted Bianco, Director of Technology transfer at the Wellcome Trust commented: "There is an urgent need to develop innovative ways to manage the transmission of antibiotic-resistant bacteria in ...

ELAD(R) Liver Support System Study Initiated at Multiple U.S. Centers

... 440 grams of immortalized human liver cells and 32,000 hollow fibers. The patient's plasma flows inside of the hollow fibers to allow two-way transfer of metabolites. During ELAD therapy the cells metabolize toxins and synthesize proteins and other liver specific products essential for life. The ...

AstraZeneca Responds to FDA Joint Advisory Committees' Recommendation on SYMBICORT(R)

... are transferred from systemically active corticosteroids. Deaths due to adrenal insufficiency have occurred in asthmatic patients during and after transfer from systemic corticosteroids to less systemically available inhaled corticosteroids. Patients who are receiving SYMBICORT twice daily ...

Gene Therapy Corrects Sickle Cell Disease in Laboratory Study

... "While this is a very useful treatment for the disease, our studies indicated that it might be possible to cure the disorder if we could use gene transfer to permanently increase fetal hemoglobin levels," said Derek Persons, M.D., Ph.D., assistant member in the St. Jude Department of Hematology. ...

Isogen Retains Strategic Partner Sheridan Road Financial to Meet Global Biopharma Demand

... critical clinical/commercial scale manufacturing transition. Isogen provides a fully integrated suite of services including formulation, technology transfer and validation services for the contract filling of liquids and lyophilized formulations for vaccines, monoclonal antibodies and other synthetic and ...

Vical Signs Binding Letter of Intent for Sales and Marketing of Allovectin-7(R) in Turkey

... EIP has agreed to obtain the necessary regulatory approvals for the territory and to pay Vical upfront and milestone payments plus a specified transfer price in exchange for the rights to an exclusive license for the territory. EIP is a leading Turkish pharmaceutical company and has multiple ...

Isogen Launches Major New Facility to Address Global Biopharma Demand

... critical clinical/commercial scale manufacturing transition. Isogen provides a fully integrated suite of services including formulation, technology transfer and validation services for the contract filling of liquids and lyophilized formulations for vaccines, monoclonal antibodies and other synthetic and ...

Celladon Announces Presentation of Clinical Data From First-in-Human MYDICAR(R) Trial for Advanced Heart Failure at American Heart Association Scientific Sessions

... has been demonstrated in clinical studies of more than 500 patients. AAV vectors are the product of decades of research focused on the safety of gene transfer agents, and are derived from components of a non-replicating, non-pathogenic, commonly occurring human virus. AAV vectors do not integrate into the ...

Pivotal Data Showed SYMBICORT(R) Improved Lung Function in Adults with COPD

... are transferred from systemically active corticosteroids. Deaths due to adrenal insufficiency have occurred in asthmatic patients during and after transfer from systemic corticosteroids to less systemically available inhaled corticosteroids. Patients who are receiving SYMBICORT twice daily should not ...

Landmark Study Demonstrates Potential of Radioimmunotherapy for Treatment of Indolent B-Cell Non-Hodgkin's Lymphoma

... countries. The reasons for this underuse have been widely debated but seem to be related, at least partially, to logistic issues involved in the transfer of care from the hematologist/oncologist to the nuclear medicine physician, concerns about inadequate reimbursement by Medicare for RIT, and ...

Lotus Pharmaceuticals, Inc.'s New Drug Laevo-Bambutero Begins Evaluation for Clinical Trials

... drugs currently on the market. Lotus obtained the patent along with exclusive production rights in China for Laevo-Bambutero through a technology transfer agreement with Dongguan Kaifa Biomedicine, Inc. in May 2008. The Company received formal notice from the SFDA that it has started to evaluate ...
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