deCODE Breakthrough in Thyroid Cancer May Enable More Targeted Risk Assessment and Earlier Intervention
... (SNPs) conferring substantial
increased risk of
thyroid cancer. The two SNPs, located on chromosomes ... SNPs, putting them at a 5.7-times greater risk of
thyroid cancer than
individuals who carry no copies of ... and they associate with
altered levels of key
thyroid hormones.
"This is an important discovery ...
New Nexavar Data Presented in Multiple Tumor Types at 44th American Society of Clinical Oncology Annual Meeting
... cancer research,
Dallas, TX. (abstract #8014).
thyroid Cancer
A Phase 2 Study of Sorafenib in Metastatic
thyroid Carcinoma
Findings from this single-arm Phase 2 ... partial responses) in patients with advanced
thyroid cancer. In the
study, Nexavar was well-tolerated; ...
Exelixis Reports Encouraging Phase 1 Data for XL184 at ASCO
... in Patients with Medullary
thyroid Cancer
CHICAGO, June 1 /PRNewswire-FirstCall/ ... and radiotherapy.
"Patients with medullary
thyroid cancer are a highly underserved
population as ... multiforme are ongoing.
About Medullary
thyroid Cancer
The American Cancer Society estimates ...
'Second Thoughts about Fluoride,' Reports Scientific American
... teeth, bones, the brain and the
thyroid gland," reports
Scientific American editors ... alter endocrine
function, especially in the
thyroid -- the gland that produces hormones
regulating ... who chaired the NRC
committee thusly, "The
thyroid changes do worry me."
Fluoride in foods, ...
Updated Phase 1 Data for Exelixis' XL184 Demonstrate Pharmacodynamic and Clinical Anti-Tumor Activity
... in patients with medullary
thyroid cancer-
SAN FRANCISCO, Oct. 23 ... the cutoff. Of seven patients
with medullary
thyroid cancer (MTC), three have had partial responses ... a marker
frequently elevated in medullary
thyroid cancer, and six of the seven
patients had a ...
You May Have a Thyroid Problem and Not Know It - Particularly If You're Over 60, Says a New Harvard Medical School Report
... -- Doctors often mistake the
symptoms of
thyroid disease for another disorder such as heart ... from
Harvard Medical School. The symptoms of
thyroid diseases are so
wide-ranging, particularly in older men and women, that doctors often
overlook
thyroid disorder as the cause and instead focus on ...
Video: Phase III Study Data With Vandetanib (Zactima(TM)) in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) Presented at American Society of Clinical Oncology
... with other anti-cancer therapies in a range of tumor types, including
thyroid cancer.
Results from the ZEPHYR (300mg monotherapy study in EGFR ... NSCLC, Phase III) and ZETA (300 mg monotherapy in advanced medullary
thyroid cancer, Phase III) studies will be available during the second half of ...
Siemens Medical Solutions Diagnostics Inks Agreement with KreLo Medical Diagnostics to Expand Thyroid Immunoassay Menu
... mimic the activity of TSH, leading to an elevated
production of
thyroid hormone. Left untreated, Graves' disease can lead to
miscarriage, birth defects,
thyroid eye disease and can be
life-threatening.
Studies have shown that the ...
Is Your Hair Taking a Break?
... weight loss (including gastric bypass surgery), the death of a loved one, starting or stopping oral contraceptives, iron deficiency, and chronic
thyroid diseases can trigger this type of hair loss.
"When I evaluate patients' hair and their recent medical history, I am able to determine if their ...
New Study Evaluating the ADHD Medication VYVANSE(R) (lisdexamfetamine dimesylate) CII Demonstrated No Change in the Pharmacokinetic Profile of VYVANSE When Coadministered with Prilosec OTC(R) 40 mg (20 mg X 2), a Commonly Used Proton Pump Inhibitor (PPI)
... child has advanced disease of the blood vessels (arteriosclerosis); symptomatic heart disease; moderate to severe high blood pressure; overactive
thyroid gland (hyperthyroidism); known allergy or unusual reactions to drugs called sympathomimetic amines (for example, pseudoephedrine); seizures; ...
Type 2 Diabetes: An Epidemic Among America's Youth
... endocrinologists, physicians whose advanced, specialized training enables them to be experts in the care of endocrine diseases such as diabetes,
thyroid disorders, growth hormone deficiency, osteoporosis, cholesterol disorders, hypertension and obesity.
...
Taking a Hard-Line Approach to Cardiovascular Risks in the Diabetes Patient
... endocrinologists, physicians whose advanced, specialized training enables them to be experts in the care of endocrine disease such as diabetes,
thyroid disorders, growth hormone deficiency, osteoporosis, cholesterol disorders, hypertension and obesity.
...
Diabetes Experts Issue New Recommendations for Inpatient Glycemic Control - Call for Systemic Changes in Hospitals Nationwide
... endocrinologists, physicians whose advanced, specialized training enables them to be experts in the care of endocrine disease such as diabetes,
thyroid disorders, growth hormone deficiency, osteoporosis, cholesterol disorders, hypertension and obesity. For more information, please call the AACE ...
Methadone Frequently Causes Menopausal Symptoms in Young Women
... replacement, vitamin and mineral supplementation.
Florida Detox and Wellness Institute tests and treats estradiol, progesterone, testosterone,
thyroid and dehydroepiandrosterone, DHEA, hormone deficiencies, caused by opiate pain medication.
Clinical research by Florida Detox and Wellness ...
Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen
... (hypertension, supraventricular arrhythmias and myocardial infarction), hypersensitivity (including anaphylaxis), endocrine disorders (including
thyroid disorders and diabetes mellitus), autoimmune disorders (including idiopathic thrombocytopenic purpura, thrombotic thrombocytopenic purpura, ...
Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C
... (hypertension, supraventricular arrhythmias and myocardial infarction), hypersensitivity (including anaphylaxis), endocrine disorders (including
thyroid disorders and diabetes mellitus), autoimmune disorders (including idiopathic thrombocytopenic purpura, thrombotic thrombocytopenic purpura, ...
Update on FDA Advisory Committee Meeting on Liraglutide for the Treatment of Type 2 Diabetes
... permitted approvability.
Finally, the Advisory Committee unanimously supported approvability of liraglutide with regard to risk of papillary
thyroid cancer.
"We remain convinced that liraglutide has a positive benefit/risk profile and represents an important advance for people ...
QuatRx Completes Enrollment of Ophena(TM)(Ospemifene Tablets) Final Pivotal Phase 3 Study in Women with Postmenopausal Vaginal Atrophy
... that is in Phase 2 as an oral treatment for the symptoms of secondary hypogonadism and other conditions in men. Sobetirome, a novel, selective
thyroid receptor beta agonist, is in Phase 1 as a potential treatment for dyslipidemia. Becocalcidiol, a novel Vitamin D analogue, is in Phase 2 clinical ...
Joint Statement from the American Diabetes Association and American Association of Clinical Endocrinologists on the NICE-SUGAR Study on Intensive Versus Conventional Glucose Control in Critically Ill Patients
... endocrinologists, physicians whose advanced, specialized training enables them to be experts in the care of endocrine disease, such as diabetes,
thyroid disorders, growth hormone deficiency, osteoporosis, cholesterol disorders, hypertension and obesity. For more information, please call the AACE ...
Shire Withdraws European Application for DAYTRANA(TM) (Methylphenidate Transdermal System)
... child has advanced disease of
the blood vessels (arteriosclerosis); symptomatic heart disease; moderate to
severe high blood pressure; overactive
thyroid gland (hyperthyroidism); known
allergy or unusual reactions to drugs called sympathomimetic amines (for
example, pseudoephedrine); seizures; ...
March 2009 Mayo Clinic Health Letter Highlights Knee Repair Surgery, Anxiety Disorder and Preventing Blood Clots
... occur on their own, independent of other health concerns. Or anxiety can be a symptom of several health conditions, such as heart or lung disease,
thyroid problems -- even dietary problems. Treating the underlying condition can help reduce or manage the anxiety.
When anxiety is the primary concern, ...
New England Journal of Medicine Publishes Results From the Landmark ATHENA Trial with Multaq(R) (dronedarone) in Atrial Fibrillation
... investigator of the ATHENA trial said "The clinical benefits observed with dronedarone in ATHENA occurred without a significantly higher rate of
thyroid or pulmonary disorders compared with placebo reported within the study period."
About the ATHENA Study
The landmark ATHENA study is the ...
New Study Shows that PEGASYS(R) Regimen Provides Higher Sustained Virological Response Rates for Hepatitis C Patients
... (hypertension, supraventricular
arrhythmias and myocardial infarction), hypersensitivity (including
anaphylaxis), endocrine disorders (including
thyroid disorders and diabetes
mellitus), autoimmune disorders (including idiopathic thrombocytopenic
purpura, thrombotic thrombocytopenic purpura, ...
Recent Study Demonstrated VYVANSE(R) (lisdexamfetamine dimesylate) CII Provided Improvements in Behavior, Inattention, and Math Test Scores from 1.5 Hours up to 13 Hours following Administration in Children with ADHD
... child has advanced disease
of the blood vessels (arteriosclerosis); symptomatic heart disease;
moderate to severe high blood pressure; overactive
thyroid gland
(hyperthyroidism); known allergy or unusual reactions to drugs called
sympathomimetic amines (for example, pseudoephedrine); seizures; ...
Study Published in Journal of Clinical Psychiatry Showed Once-Daily VYVANSE(R) (lisdexamfetamine dimesylate) Significantly Improved ADHD Symptoms in One of the Largest Controlled Stimulant Trials in Adults with ADHD
... child has advanced disease
of the blood vessels (arteriosclerosis); symptomatic heart disease;
moderate to severe high blood pressure; overactive
thyroid gland
(hyperthyroidism); known allergy or unusual reactions to drugs called
sympathomimetic amines (for example, pseudoephedrine); seizures; ...
Lilly and Deciphera Pharmaceuticals Announce Licensing and Collaboration Agreement
... is one of the most frequently mutated members of the kinase
family across all cancers, and is particularly common in malignant
melanomas, colon, and
thyroid cancers. The V600E mutant form of BRAF kinase
in particular has been associated with increased tumor aggressiveness and
decreased survival rates in ...
American Heart Journals Publishes Results From ERATO Trial Showing Dronedarone (Multaq(R)) Improves Ventricular Rate Control in Patients With Permanent Atrial Fibrillation
... after seven days.
Values returned to baseline within one week after treatment discontinuation
with no impact on renal function. No evidence of
thyroid or pulmonary
fibrosis was observed with dronedarone and no Torsade de Pointes was
reported during the six-month follow-up.
ERATO (The Efficacy and ...
Prescription Sleeping Pill Use Tied to Cancer
... that took sleeping pills compared to
none in the placebo groups.
Lab animals given high doses of hypnotic drugs are known to have
developed kidney,
thyroid and testicular cancers and suffer chromosome
damage, which is a sign of carcinogenicity. Although a direct causal link
between cancer and sleeping ...
Multaq(R) (dronedarone) Granted FDA Priority Review for Patients with Atrial Fibrillation
... potassium and sodium channels and has
anti-adrenergic properties. Dronedarone does not contain the iodine radical
and did not show any evidence of
thyroid or pulmonary toxicity in clinical
trials.
About sanofi-aventis
Sanofi-aventis, a leading global pharmaceutical company, discovers,
develops and ...
Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III Melanoma Demonstrated Significant and Sustained Impact on Relapse-Free Survival
... (low white blood cell count), thrombocytopenia (low
platelet count) and neutropenia (low neutrophil count); thyroiditis
(inflammation of the
thyroid gland); and autoimmunity (production of
antibodies against the body's own tissues).
About Peg-IFN
Interferon is a protein produced naturally by ...
ATHENA Clinical Results with Dronedarone (Multaq(R)) Highlighted at the World Cardiology Congress
... potassium and sodium channels and has
anti-adrenergic properties. Dronedarone does not contain the iodine radical
and did not show any evidence of
thyroid or pulmonary toxicity in clinical
trials.
Based upon this new clinical data, sanofi-aventis plans to submit a
registration dossier to the European ...
ATHENA Clinical Results for Dronedarone (Multaq(R)) Highlighted at the World Cardiology Congress
... potassium and sodium channels and has
anti-adrenergic properties. Dronedarone does not contain the iodine radical
and did not show any evidence of
thyroid or pulmonary toxicity in clinical
trials.
Based upon the new ATHENA clinical data, sanofi-aventis plans to submit
a registration dossier to the ...
PEGASYS(R)/COPEGUS(R) Show Benefit in Hard-to-Treat Latino Population with Hepatitis C
... (hypertension,
supraventricular arrhythmias and myocardial infarction), hypersensitivity
(including anaphylaxis), endocrine disorders (including
thyroid disorders
and diabetes mellitus), autoimmune disorders (including idiopathic
thrombocytopenic purpura, thrombotic thrombocytopenic purpura, ...
Landmark ATHENA Study Findings With Multaq(R) (dronedarone) Shows 24% Reduction In Cardiovascular Hospitalization or Death in Patients With Atrial Fibrillation
... potassium and sodium channels and has
anti-adrenergic properties. Dronedarone does not contain the iodine radical
and did not show any evidence of
thyroid or pulmonary toxicity in clinical
trials.
About sanofi-aventis in Cardiology and Thrombosis
Sanofi-aventis' unmatched experience in the treatment ...
Results of the Phase III Pivotal Study of VYVANSE(TM) (Lisdexamfetamine Dimesylate) for the Treatment of ADHD in Adults Presented at National Scientific Meeting of Psychiatrists
... child has advanced disease
of the blood vessels (arteriosclerosis); symptomatic heart disease;
moderate to severe high blood pressure; overactive
thyroid gland
(hyperthyroidism); known allergy or unusual reactions to drugs called
sympathomimetic amines (for example, pseudoephedrine); seizures; ...
Siemens Healthcare Diagnostics Launches B12, Folate, and Ferritin Tests on Its Dimension vista Intelligent Lab System
... and Transferrin testing by
nephelometric methodology. The Dimension Vista Intelligent Lab system menu
offers panels for anemia, cardiac disease,
thyroid disorders, therapeutic
drug monitoring, protein testing, drugs-of-abuse testing, and routine and
specialty chemistry testing.
About Siemens ...
Roche responds to announcement of 'IDEAL' hepatitis C trial results
... (hypertension, supraventricular
arrhythmias and myocardial infarction), hypersensitivity (including
anaphylaxis), endocrine disorders (including
thyroid disorders and diabetes
mellitus), autoimmune disorders (including idiopathic thrombocytopenic
purpura, thrombotic thrombocytopenic purpura, ...
Exelixis Initiates Phase 1/2 Trial of XL184 in Patients With Non-Small Cell Lung Cancer
... as of the June 22, 2007 cutoff;
further data were also provided for six additional patients after the
cutoff. Of seven patients with medullary
thyroid cancer (MTC), three had
partial responses (two confirmed and one unconfirmed) as of the date of the
AACR-NCI- EORTC Conference. In addition, as of ...
AstraZeneca Completes Enrollment in First Phase III Study of the Investigational Drug Vandetanib (ZACTIMA)(R) in Non-Small Cell Lung Cancer
... either alone or in combination with standard
chemotherapy (docetaxel). (1)(2) Vandetanib is also being evaluated as a
treatment option in medullary
thyroid cancer and has been awarded Food and
Drug Administration (FDA) orphan drug status and fast track designation for
this indication.
About ...
Biological Psychiatry Publishes Study Showing VYVANSE Demonstrated Significant Efficacy for Treatment of ADHD for up to 12 Hours After Administration
... child has advanced disease of the
blood vessels (arteriosclerosis); symptomatic heart disease; moderate to
severe high blood pressure; overactive
thyroid gland (hyperthyroidism);
known allergy or unusual reactions to drugs called sympathomimetic amines
(for example, pseudoephedrine); seizures; ...