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Swelling in Medical Technology

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

... arthropathy manifesting with joint pain and swelling that can lead to joint destruction and ... of heart failure like shortness of breath or swelling of your lower legs or feet. Rarely, people ... very tired, chest pain or shortness of breath, swelling of the feet, ankles, and/or legs. Tell your ...

Chronic Ankle Pain May Be More Than Just a Sprain

... Tendon injuries can include tendonitis or swelling around the tendons. In more severe cases, the peroneal tendons can actually tear or there can be a swelling of the tendons behind the fibula bone. This can ... pain that is not responding to treatment swelling and tenderness around the outside of the ankle ...

Shire to add New Orphan Drug to its HGT Portfolio - EU Launch Imminent

... disease characterized by unpredictable recurring swelling attacks in the hands, feet, face, larynx, and ... tract result in severe pain caused by swelling in the intestinal wall. Attacks that affect the larynx are life-threatening because swelling of the larynx constricts the upper airways and ...

New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients

... get new or worsening symptoms of heart failure like shortness of breath or swelling of your lower legs or feet. Rarely, people using TNF blockers can ... or muscle pain, becoming very tired, chest pain or shortness of breath, swelling of the feet, ankles, and/or legs. Tell your doctor if you are ...

New One-Year Data from REMICADE(R) SONIC Trial Show Sustained Efficacy Compared with Azathioprine in Treatment of Crohn's Disease

... Heart failure - new or worsening symptoms, such as shortness of breath, swelling of ankles or feet, or sudden weight gain. Reactivation of HBV - ... - hives, difficulty breathing, chest pain, high or low blood pressure, swelling of face and hands, and fever or chills. Lupus-like syndrome - ...

Scientific Data Relating to Cinryze(TM) Presented at 6th Annual C1 Inhibitor Deficiency Workshop

... in an abstract entitled, 'Infusion of C1 Inhibitor as Therapy for swelling in Hereditary Angioedema Patients Reverses Abnormalities of the Plasma ... these parameters were reassessed after treatment of episodes of swelling with intravenous C1 inhibitor. Abstract book page ...

Children and Orthopaedic Surgical Emergencies

... within days can lead to: A high fever Severe swelling Redness and a great deal of pain If the infection ... a bike," said Dr. Herman. "One of the tips for parents is that immediate swelling or deformity is almost always associated with a fracture. When you ...

Study Demonstrates Restylane(R) Effect Lasted 18 Months in 97% of Patients With One Repeat Injection

... improvement in WSRS over baseline Adverse events were primarily swelling (24%) and bruising (19%); none were serious. For more ... sun and UV lamp exposure and extreme cold weather until any initial swelling and redness have resolved. Safety has not been established for use during ...

New Findings Show Efficacy of REMICADE(R) Compared With Azathioprine in Treatment of Crohn's Disease According to First-of-its Kind Study

... new or worsening symptoms of heart failure (such as shortness of breath, swelling of your ankles or feet or sudden weight gain). Reactivation of hepatitis ... hives, difficulty breathing, chest pain, high or low blood pressure, swelling of face and hands, and fever or chills. Tell your doctor if you ...

Auxilium Pharmaceuticals, Inc. Announces XIAFLEX(TM) Meets Primary Endpoint With Statistical Significance (p<0.001) in CORD I Pivotal Phase III Study for Dupuytren's Contracture

... bruising and pruritis at the injection site and transient lymph node swelling and pain. In over 2,000 XIAFLEX injections administered in approximately ... bruising and pruritis at the injection site and transient lymph node swelling and pain. These adverse events were consistent with previous trials. No ...

New Analysis Shows Efficacy of REMICADE(R) in Treatment of Ulcerative Colitis in Patients with Recent Disease Onset or Long-Standing Disease

... new or worsening symptoms of heart failure (such as shortness of breath, swelling of your ankles or feet or sudden weight gain). Reactivation of hepatitis ... hives, difficulty breathing, chest pain, high or low blood pressure, swelling of face and hands, and fever or chills. Tell your doctor if you ...

New Deep Vein Thrombosis (DVT) Registry Data Show Clot Quickly Removed, Blood Flow Restored in Large Patient Registry

... blood clots in the future. Patients experience dramatic relief of pain, swelling and skin discoloration in just a few hours," says Gerard J. O'Sullivan, ... clots will cause PTS, a condition characterized by chronic leg pain, swelling and ulcers. The clot may eventually dissolve on its own, but in the ...

CSL Behring Submits BLA Requesting Approval of C1-Esterase Inhibitor for the Treatment of Hereditary Angioedema

... in an autosomal dominant manner. Symptoms include episodes of edema or swelling in the hands and feet, the face, the abdomen, and/or the larynx. Patients ... episodes of severe pain, diarrhea, nausea, and vomiting caused by swelling of the intestinal wall. Attacks that involve the face and larynx can ...

REMICADE-Treated Patients Experienced Rapid and Substantial Improvement in Psoriasis in Critical Regions of Body

... new or worsening symptoms of heart failure (such as shortness of breath, swelling of your ankles or feet, or sudden weight gain). Reactivation of ... hives, difficulty breathing, chest pain, high or low blood pressure, swelling of face and hands, and fever or chills. Tell your doctor if you ...

Takeda Provides Update on the Investigational Fixed-Dose Combination of alogliptin and ACTOS(R) (pioglitazone HCl)

... with insulin or sulfonylureas, you may be at risk for low blood sugar. Some people taking ACTOS may experience flulike symptoms, mild-to-moderate swelling of legs and ankles, anemia, and weight gain. Patients with diabetes should have regular eye exams. If you experience vision problems, consult your ...

FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent

... lupus, or if you take lithium. Two of the most serious side effects of TEKTURNA and TEKTURNA HCT include an allergic reaction involving swelling of the face, lips, throat and/or tongue that may cause difficulty in breathing and swallowing (stop taking TEKTURNA or TEKTURNA HCT and contact your ...

Landmark Study for GSK's Cervical Cancer Vaccine Published in The Lancet

... cancer-causing HPV types. It has been shown to be generally well tolerated. The most common symptoms after vaccination included pain, redness and swelling at the injection site, fatigue, fever, aching, headache, itching, rash or gastrointestinal disturbances. To date, Cervarix (R) has been ...

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... to the disease. About Psoriatic Arthritis Psoriatic arthritis is a chronic inflammatory arthropathy manifesting with joint pain and swelling that can lead to joint destruction and debilitation over time. The Arthritis Research Campaign estimates one in 50 people have psoriasis. Of these, ...

HEALTHPOINT-Sponsored Venous Leg Ulcer Clinical Trial Enrolls First Subject for Second Phase II Study

... a 12-week treatment period. All trial patients undergo compression bandaging with a four-layer system (Profore(R) System) in order to control leg swelling caused by the underlying vein dysfunction. About HP802-247 HP802-247 consists of two components that are sprayed sequentially on the wound ...

Celladon Provides MYDICAR(R) Program Update of First-In-Human Trial for Advanced Heart Failure at American Society of Gene Therapy Annual Meeting

... failure contributes to or causes about 280,000 deaths annually. The most common symptoms of heart failure are shortness of breath, feeling tired, and swelling in the ankles, feet, legs, and sometimes the abdomen. There is no cure for heart failure. About Celladon Celladon Corporation, based in La ...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

... are generally mild to moderate. Commonly reported side effects for Femara include hot flashes, fatigue, joint pain, headache, increase in sweating, swelling due to fluid retention, increase in cholesterol, dizziness, constipation, nausea, cardiovascular ischemic events, muscle pain, osteoporosis, ...

Ferring Pharmaceuticals Unveils Six-Month Efficacy Data for EUFLEXXA(R) for the Treatment of Osteoarthritis Knee Pain

... skin diseases in the area of the injection site. Common adverse events reported were arthralgia (joint pain) and back pain. Temporary knee pain and swelling may occur after injection. Strict aseptic technique must be followed to avoid joint infection. About Ferring Pharmaceuticals Inc. Ferring ...

Ferring Pharmaceuticals Launches Phase IIIB Trial of Degarelix as Intermittent Therapy

... prostate cancer. The most commonly observed adverse reactions during degarelix therapy included injection site reactions (e.g. pain, erythema, swelling or induration), hot flashes, increased weight, fatigue, and increases in serum levels of transaminases and gamma-glutamyltransferase (GGT). ...

NHS National Innovation Centre Cites VNUS Closure(R) Procedure as Select Innovative Technology

... in the legs as a result of venous reflux and faulty valves in the leg veins. Left untreated, venous reflux can lead to painful varicose veins, swelling in the lower limbs, and skin problems, such as itching, redness, eczema, and leg ulcers. For the past century, the traditional treatment for ...

Vantia Therapeutics' Pipeline Continues to Mature

... in the treatment of hereditary angioedema (HAE). HAE, which is thought to affect up to 15,000 people world wide, is characterised by episodes of swelling in various parts of the body including the airways. It can lead to pain, nausea, vomiting and death by asphyxiation, and an oral treatment would be ...

New Study Suggests Cholesterol-Lowering Statins Reduce Severe Asthma Attacks that Result in Hospitalizations and Emergency Room Visits

... of these medications as well." Inflammation and Asthma Treatments Asthma is a chronic respiratory disease caused by inflammation and swelling of the airways and constriction of the muscles of the bronchial passages. Currently, the recommended drug therapies for treating asthma include the ...

Fast-Acting, Long-Lasting Topical Relief From Arthritis Pain

... a dietary supplement that relieves arthritis pain in three specific ways: first, by blocking the transmission of pain signals; second, by reducing swelling in the joints; and third, by decreasing inflammation in the affected tissues. Together, Arthri-Zen Relief Cream(R) and Arthri-Zen Relief(R) ...

March 2009 Mayo Clinic Health Letter Highlights Knee Repair Surgery, Anxiety Disorder and Preventing Blood Clots

... Many DVTs can develop and grow quite large before symptoms appear. Eventually, in most cases, symptoms are present and can include: swelling in the ankle area of the affected leg. Typically only one leg is affected. Leg pain that often starts in the calf and can feel like a cramp. ...

ThromboGenics Completes Patient Enrolment for Phase II Trial of Microplasmin for the Treatment of Diabetic Macular Edema (MIVI II DME)

... is a major cause of visual loss and the leading cause of blindness in patients aged 20-60. Diabetic Macular Edema (DME) is a condition where swelling of the retina occurs in patients with diabetic retinopathy, due to a leakage of fluid from blood vessels within the macula. The only approved ...

Study Finds Family History, Higher Incidence of Sunburns Associated With Rosacea

... SAN FRANCISCO, March 5 /PRNewswire-USNewswire/ -- Rosacea is a chronic skin condition that causes redness, swelling and vascular abnormalities, most commonly on the face, with varying degrees of severity. While the exact cause of rosacea is unknown, dermatologists ...

Video: Femara(R) First Aromatase Inhibitor to Indicate Survival Benefit Versus Tamoxifen When Taken for Five Years After Breast Cancer Surgery

... are generally mild to moderate. Commonly reported side effects for Femara include hot flashes, fatigue, joint pain, headache, increase in sweating, swelling due to fluid retention, increase in cholesterol, dizziness, constipation, nausea, cardiovascular ischemic events, muscle pain, osteoporosis, ...

Observational Study Finds Changes in Medicare Reimbursement for Erythropoiesis-Stimulating Agents Associated With Increased Need for Blood Transfusion

... of hypertension or cardiovascular disease. In studies, the most common side effects included fever (pyrexia), diarrhea, nausea, vomiting, swelling of hands or feet (edema), lack or loss of strength or weakness (asthenia, fatigue), shortness of breath, high blood pressure, headache, joint pain ...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

... are generally mild to moderate. Commonly reported side effects for Femara include hot flashes, fatigue, joint pain, headache, increase in sweating, swelling due to fluid retention, increase in cholesterol, dizziness, constipation, nausea, cardiovascular ischemic events, muscle pain, osteoporosis, ...

Celladon Announces Presentation of Clinical Data From First-in-Human MYDICAR(R) Trial for Advanced Heart Failure at American Heart Association Scientific Sessions

... failure contributes to or causes about 280,000 deaths annually. The most common symptoms of heart failure are shortness of breath, feeling tired, and swelling in the ankles, feet, legs, and sometimes the abdomen. There is no cure for heart failure. About Celladon Celladon was launched in October 2004 as ...

Study Shows Potential Benefits of Xolair(R) in Treating Children Suffering from Moderate or Severe Persistent Allergic Asthma Inadequately Controlled With Inhaled Corticosteroids

... dizziness, fainting, rapid or weak heartbeat, anxiety, or feeling of "impending doom" -- flushing, itching, hives, or feeling warm -- swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing Patients should not receive Xolair if they have ever had an ...

Data From Investigational Use of PROCRIT(R) (Epoetin alfa) Presented at American Society of Nephrology Annual Meeting

... of hypertension or cardiovascular disease. -- In studies, the most common side effects included fever (pyrexia), diarrhea, nausea, vomiting, swelling of hands or feet (edema), lack or loss of strength or weakness (asthenia, fatigue), shortness of breath, high blood pressure, headache, ...

Study Shows EUFLEXXA(R) Patients Report Significant Improvements in Osteoarthritis of the Knee Pain over a Six Month Period

... events reported with EUFLEXXA(R) at an incidence of 5% or greater were arthralgia (joint pain) (8.75%) and back pain (5%). Temporary knee pain and swelling may occur after injection with EUFLEXXA(R). The safety and effectiveness of injecting EUFLEXXA(R) into the knee together with other injectable ...

IDM Pharma Provides Update on Mifamurtide (L-MTP-PE) Regulatory Status Following September Meeting of European Committee for Medicinal Products for Human Use (CHMP)

... tibia, and humerus, and in the area of the bone that has the fastest growth rate, they can occur in any bone. The most common symptom is pain, but swelling and limited movement can occur as the tumor grows. Osteosarcoma is an orphan disease with fewer than 1,000 new cases diagnosed in the United States ...

APTA Supports Surgeon General's 'Call to Action' to Prevent Deep Vein Thrombosis and Pulmonary Embolism

... toe cramping, and general lower-body aching," says former APTA President Marilyn Moffat, PT, PhD, DPT. "Sitting still for long periods may lead to swelling of the feet, which becomes obvious to many passengers when they try to put their shoes back on at the end of their flight," Moffat says. APTA ...

Pivotal National Trial Uses Newest Interventional Radiology Treatment to Bust Blood Clots in Legs

... blood clot continues to block the vein and permanently damages its one-way valves, resulting in the pooling of blood in the leg, chronic leg pain, swelling and fatigue and sometimes skin ulcers. It's logical that immediate clot removal will prevent PTS," said Vedantham. The ATTRACT trial -- the first ...
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