SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
... percent of SIMPONI treated patients had injection
site reactions compared with 2.2 percent in control-treated patients. The majority of the injection
site reactions were mild and moderate, and the most frequent manifestation was injection
site erythema.
For the Full U.S. ...
New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients
... percent and 1 percent of patients, and injection
site reactions (ISR) through week 16 occurred in 3 ... nausea, abnormal liver tests, redness at
site of injection, high blood pressure, bronchitis, ... company is based in Kenilworth, N.J., and its Web
site is www.schering-plough.com .
...
Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis
... experiencing serious adverse events. Injection
site reactions occurred in eight percent of patients ... experiencing serious adverse events. Injection
site reactions occurred in 11 percent of patients ... nausea, abnormal liver tests, redness at
site of injection, high blood pressure, bronchitis, ...
FDA Approves Vanda Pharmaceuticals' Fanapt(TM) for the Treatment of Schizophrenia
... Relations tab and are advised to go to the Web
site at least 15 minutes early to register, download, ... The call will also be archived on the Vanda Web
site for a period of 30 days, through June 6, 2009.
... are available free of charge at the SEC's web
site at www.sec.gov or from Vanda at ...
Transcept Pharmaceuticals to Report First Quarter 2009 Results
... from the Investors section on the corporate web
site at www.transcept.com . A webcast replay can be accessed on the corporate web
site beginning May 13, 2009 at the same time as the conference call and will remain on the
site through May 27, 2009.
About Transcept ...
Ferring Pharmaceuticals Launches Phase IIIB Trial of Degarelix as Intermittent Therapy
... during degarelix therapy included injection
site reactions (e.g. pain, erythema, swelling or ... Specifically relating to the injection
site adverse reactions, most were transient, of mild ... (<1%). Grade 3 (severe) injection
site reactions occurred in two percent or less of ...
Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting
... PEGINTRON or PEGINTRON/REBETOL are injection
site inflammation/reaction, fatigue/asthenia, ... neutropenia, fatigue, anorexia, injection
site erythema and vomiting.
In a study with ... was a 23-24% incidence overall for injection
site reactions or inflammation.
Individual ...
Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients
... PEGINTRON or PEGINTRON/REBETOL are injection
site inflammation/reaction, fatigue/asthenia, ... neutropenia, fatigue, anorexia, injection
site erythema and vomiting.
In a study with ... was a 23-24% incidence overall for injection
site reactions or inflammation.
Individual ...
Innocoll Announces Dosing of Last Patient in Second US Phase 3 Clinical Trial to Investigate GENTAMICIN SURGICAL IMPLANT for Prevention of Surgical Site Infections in Colorectal Surgery Patients
... SURGICAL IMPLANT for the prevention of surgical
site infections.
The trial is being conducted at ... considered to be the most prone to surgical
site infection (SSI). Patients in the treatment group ... demonstrated a 70 percent decrease in surgical
site infections from 18.4 percent in the control group ...
Innocoll Announces Dosing of Last Patient in US Phase 3 Clinical Trial to Investigate GENTAMICIN SURGICAL IMPLANT for Prevention of Surgical Site Infections in Cardiac Surgery Patients
... SURGICAL IMPLANT for the prevention of surgical
site infections.
The trial is being conducted at ... tissue infections and the prevention of surgical
site infections in both hard and soft tissues. ... trials in the U.S. for the prevention of surgical
site infections and has received FDA fast-track ...
FDA Approves an Expanded Indication for Peginterferon-Based Combination Therapy for Patients With Chronic Hepatitis C
... PEGINTRON or PEGINTRON/REBETOL are injection
site inflammation/reaction, fatigue/asthenia, ... neutropenia, fatigue, anorexia, injection
site erythema and vomiting.
In a study with ... was a 23-24% incidence overall for injection
site reactions or inflammation.
Individual ...
Inclinix Releases Next Generation Critical Population Research(R) (CPR) for Clinical Trial Investigator Site Selection and Patient Recruitment
... private databases, CPR analyzes each
investigator
site for multiple criteria to identify the optimal ... database, provides a powerful dataset for
site selection and
patient recruitment.
"The clinical trials industry has repeatedly identified
site initiation as
a primary cause of delays," ...
Schering-Plough Provides Update on Boceprevir Clinical Development and Introduces Potent Next-Generation Oral HCV Protease Inhibitor for Treating Patients With Chronic Hepatitis C
... however, the incidence of some (e.g., injection
site reactions, fever, rigors, nausea) were higher. ... in severity as treatment continues. Application
site disorders were common (47%), but all were mild ... no patient discontinued, and included injection
site inflammation and reaction (i.e., bruise, ...
Video: New Survey Finds Mothers See Influenza as a Serious Health Threat, but Often Don't Get Their Families Vaccinated
... how it can be prevented through vaccination. The
site offers reporters, consumers and health-care ... service. By typing in their 5-digit zip code,
site visitors can receive a list of immunization clinics in their area.
site visitors may also schedule reminders and sign up ...
Colesevelam HCl Lowered LDL Cholesterol in Pediatric Patients With Heterozygous Familial Hypercholesterolemia
... (877-431-7763), or
go to the Welchol web
site at http://www.Welchol.com .
About Daiichi ...
s-treatment-familial-hypercholesterolemia.htm.
site accessed September 19,
2008.
(2) ...
s-treatment-familial-hypercholesterolemia.htm.
site accessed September 19,
2008.
(4) American ...
Boceprevir Phase II Study Showed High Rate of Sustained Response With 28- and 48-Week Regimens in Genotype 1 Treatment-Naive Hepatitis C Patients
... however, the incidence of some (e.g., injection
site reactions,
fever, rigors, nausea) were higher. ... in severity as treatment
continues. Application
site disorders were common (47%), but all were ... (i.e., bruise, itchiness, irritation).
Injection
site pain was reported in 2% of patients receiving ...
NanoBio Demonstrates New Topical Approach to Treating Nail Fungus That Circumvents Problems with Current Therapy
... they cannot
penetrate the nail and access the
site of infection. The results were
reported this ... dermis to more than 1 centimeter away from the
site of
application," said Susan Ciotti, Ph.D., ... because they are unable to penetrate to the
site of infection.
"The safe and efficient delivery ...
ULURU Inc. Announces the Commencement of First Clinical Study Using Altrazeal(TM) Silver
... - Multi-Center Study in Skin Graft Donor
site Patients -
ADDISON, Texas, Oct. 21 ... patients being enrolled. The first study
site has been initiated
and the Company plans to ... with Altrazeal(TM)
Silver being applied to one
site and the competitive dressing being applied
to the ...
Photos: NIH Launches New Web Site for Parents on Medical Research Studies for Children
... improves their
health and well-being. A new Web
site from the National Institutes of
Health (NIH), ... to enroll their
child in a study."
The Web
site describes why research in children is important, ... and other conditions --
developed the Web
site in collaboration with New England ...
deCODE Files IND for DG071, a Novel PDE4 Modulator Being Developed for Alzheimer's and Other Cognitive Disorders
... of these molecules in the PDE4
enzymatic active
site competitively with cAMP. As cAMP is of ... deCODE chemistry team to
identify a novel binding
site for allosteric modulators in the PDE4
regulatory domain. Binding of an allosteric modulator at that
site is
non-competitive with cAMP. DG071 has been ...
F.D.A. Approves SANCUSO(R), the First and Only Patch for Preventing Nausea and Vomiting in Cancer Patients Undergoing Chemotherapy
... adverse
reaction was constipation. Application
site reactions were reported but
were mild and did not ... by the underlying condition. Mild application
site reactions have
occurred; remove patch if severe ... should avoid direct exposure of application
site to natural
or artificial sunlight by covering ...
Novare Announces Successful Series of Single Port Lap Band Procedures With RealHand(R) High Dexterity Instruments
... upper
abdominal trocar placement that is often a
site for significant patient
discomfort.
"This is a ... said Dr. Teixeira. "By reducing the operative
site to
one single incision in the belly button we are ... For more information, visit the company's web
site at
http://www.novaresurgical.com .
...
Innocoll Announces Dosing of Last Patient in US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of Post-Operative Pain
... to provide pain control directly
at the surgical
site and thus reduce the level of additional ... to provide continuous,
long-term analgesia at the
site of a surgical wound.
Innocoll has already ... in post-operative
pain, prevention of surgical
site infection, and treatment of diabetic ...
Top-Line Results of Boceprevir Phase II Study Showed High Rate of Sustained Response (SVR) in Genotype 1 Treatment-Naive Hepatitis C Patients
... however, the incidence of some (e.g., injection
site reactions,
fever, rigors, nausea) were higher. ... in severity as treatment
continues. Application
site disorders were common (47%), but all were ... (i.e., bruise, itchiness, irritation).
Injection
site pain was reported in 2% of patients receiving ...
FDA Clears the Pathwork(R) Tissue of Origin Test for Hard-To-Identify Tumors
... in the U.S. may have a tumor for which the
site of
origin is uncertain after the initial ... better decisions.
"Knowing the primary tumor
site with greater certainty enables more
appropriate ... identification of the primary tumor
site or tissue of origin.
Targeting therapy to ...
Data Presented at American Headache Society's Annual Scientific Meeting Show Primary Endpoint Met as Well as Improvement on Important Secondary Endpoints in Phase IIb Acute Migraine Trial of TorreyPines Therapeutics' Tezampanel
... adverse events compared to placebo were
injection
site pain (5.1 percent vs. 20 percent), injection
site burning
(3.8 percent vs. 6.7 percent), dizziness ... indicated above, the reported rates of "injection
site ...
TorreyPines Therapeutics to Host Webinar at 11 a.m. EDT Today on the Opportunity for Treating Chronic Pain, Migraine and Muscle Spasticity Through Inhibition of Neurotransmitter Glutamate
... By acting at both the
AMPA and kainate receptor
site to competitively block the binding of
glutamate, ... on
the home page of TorreyPines Therapeutics' Web
site at
http://www.torreypinestherapeutics.com . ... available on TorreyPines Therapeutics' Web
site until July 25.
About TorreyPines Therapeutics
...
Auxilium Pharmaceuticals, Inc. Announces XIAFLEX(TM) Meets Primary Endpoint With Statistical Significance (p<0.001) in CORD I Pivotal Phase III Study for Dupuytren's Contracture
... swelling, bruising and pruritis at the injection
site and
transient lymph node swelling and pain. In ... be simultaneously web cast on Auxilium's web
site and archived for
future review until July 3, ... tab on the home page of the Company's web
site at http://www . auxilium.com Web cast: ...
Treprostinil Data Presented at American Thoracic Society Conference Demonstrates Significant Clinical Progress in All Four Routes of Administration
... of 40 ng/kg/min, infrequent
subcutaneous catheter
site changes, and proactive pain management. ... administration of Remodulin (e.g., infusion
site pain), they
tolerate treatment very well and ... of
infusion. For subcutaneous infusion, infusion
site pain and infusion site
reaction (redness and ...
Abbott Presents Long-Term Data From Extension Study Showing Adult Crohn's Patients Treated With HUMIRA(R) (Adalimumab) Maintained Remission
... adverse reactions vs. placebo were
injection
site reactions (20 percent vs. 14 percent), upper ... (17 percent vs. 13 percent), injection
site pain (12 percent vs.
12 percent), headache (12 ... Medication Guide, is available on the Web
site http://www.humira.com or
in the United States ...
Schering-Plough To Initiate Phase III Studies With HCV Protease Inhibitor Boceprevir in Previously Untreated Hepatitis C Patients and Those Who Failed Prior Treatment
... however, the incidence of some (e.g., injection
site reactions,
fever, rigors, nausea) were higher. ... in severity as treatment
continues. Application
site disorders were common (47%), but all were ... (i.e., bruise, itchiness, irritation).
Injection
site pain was reported in 2% of patients receiving ...
Amikacin Inhale Shows Promising Results in Phase II Study
... shows that
targeting antibiotic therapy to the
site of infection might offer superior
bacterial ... delivers the
antibiotic directly to the
site of infection, without reaching high
systemic ... Inhale, which fights pneumonia directly
at the
site of infection, may be able to help decrease ...
ADVENTRX Announces ANX-530 Safety Data From Registrational Bioequivalence Clinical Study
... reduction
in general disorders and administration
site conditions when compared to
Navelbine(R) ... entitled
"Tolerability and incidence of infusion
site reactions with emulsion
formulation of ... of ADVENTRX. "The improvement
in injection
site reactions could translate into a real benefit ...
Schering-Plough Highlights PEGINTRON(TM) and Boceprevir Hepatitis C Data Presentations at Digestive Disease Week (DDW) Annual Meeting
... however, the incidence of some (e.g., injection
site reactions,
fever, rigors, nausea) were higher. ... in severity as treatment
continues. Application
site disorders were common (47%), but all were ... (i.e., bruise, itchiness, irritation).
Injection
site pain was reported in 2% of patients receiving ...
Azor(TM) Reduces Blood Pressure in Difficult to Treat Special Populations
... call 877-4-DSPROD (877-437-7763) or go to
the web
site http://www.azor.com .
About Daiichi Sankyo, ... (5) http://www.cdc.gov/nchs/nhanes.htm
site accessed 5/14/2008 (6) Chobanian, A.V., et al. ...
site accessed 5/17/2007 (8) ...
New Data Shows 45 Percent of Patients with Stage 1 Hypertension Reached Normotension with BENICAR(R) and BENICAR HCT(R)
...
site accessed 4/18/2008 3. Kearney, P. et al. ...
site accessed 4/18/2008 5. http://www.americanheart.org/presenter.jhtml?identifier=4621
site accessed 4/18/2008
...
Siemens and LabCorp Enter Agreement to Co-Develop New Clinical Diagnostic Tests
... learn more about
our organization, visit our Web
site at: http://www.labcorp.com .
(1) American Heart Association (AHA) 2008. Web
site accessed Febuary 15, 2008: ... (2) World Health Organization (WHO) 2008. Web
site accessed Feburary 15, 2008: ...
Phosphagenics Reports Positive Pre-clinical Results for Targeted Delivery of Lidocaine
... TPM to deliver
lidocaine (5%) to a targeted local
site after a single topical application,
while ... concentrations were measured
in the skin at the
site of application, as well as in the underlying ... concentrations were measured in the skin
at the
site of application, as well as in the underlying ...
Innocoll Announces Dosing of First Patient in US Phase 2 Clinical Trial to Investigate CollaRx(R) GENTAMICIN TOPICAL for the Prevention of Diabetic Foot Infections
... infections and the prevention of surgical
site infections in both
hard and soft tissues; and is ... in the
US for the prevention of surgical
site infections. The development of the
topical ... for the
treatment and prevention of surgical
site infections, is approved for sale
in 49 countries ...
Interim Results from Boceprevir Phase II Study in Genotype 1 Treatment-Naive Hepatitis C Patients Presented At EASL
... however, the incidence of some (e.g., injection
site reactions,
fever, rigors, nausea) were higher. ... in severity as treatment
continues. Application
site disorders were common (47%), but all were ... (i.e., bruise, itchiness, irritation).
Injection
site pain was reported in 2% of patients receiving ...