BioCryst Pharmaceuticals Reports Positive Results of Shionogi & Co. Sponsored Phase 3 Studies of i.v. Peramivir for Influenza
... that compared the efficacy and safety of a single
dose of peramivir (either 300 mg or 600 mg) and ... Korea:25; Taiwan:21). Both the 300 mg and 600 mg single
dose peramivir groups demonstrated ...
i.v. peramivir 300 mg and 600 mg in both single
and multiple doses were generally safe and ...
Keryx Biopharmaceuticals, Inc. Commences Phase 1 Study of KRX-0401 (Perifosine) in Recurrent Pediatric Solid Tumors at Memorial Sloan-Kettering Cancer Center
... study to evaluate KRX-0401 (perifosine) as a single
agent treatment for recurrent solid tumors in ... the National Cancer Institute demonstrated that single
agent perifosine not only induced tumor ... open-label, Phase 1 study is entitled "Study of single
Agent Perifosine for Recurrent Pediatric Solid ...
Single Port Surgeries Now Performed at University Medical Center at Princeton
... now performing laparoscopic surgery by way of a single
incision through the belly button -- becoming one ... the cosmetic issue of multiple scars.
port laparoscopic surgery, only one incision is ... surgery, from multiple incisions to just a single
incision in the belly button," said Henry ...
PARI Pharma Reports Successful Phase Ib Clinical Results for Inhaled Liposomal Cyclosporine A and Gains FDA Orphan Drug Designation for the Prevention and Treatment of Bronchiolitis Obliterans
... double lung transplants and seven patients had single
lung transplants. Patients were given a single
dose application of 10mg or 20mg of liposomal ... development of bronchiolitis obliterans is the single
most important risk factor for five-year ...
Keryx Biopharmaceuticals Reports Single Agent Phase 2 Data of KRX-0401 (Perifosine) Further Demonstrating KRX-0401's Activity in the Treatment of Advanced Metastatic Renal Cell Cancer
... KRX-0401 Demonstrates Impressive single
Agent Efficacy in Patients who Progressed after ... as a secondary endpoint. Best response to single
agent perifosine was as follows:
... For this group, best response and median PFS to single
agent perifosine was as follows:
Intercell AG Announces First Subject Enrolled in a Phase II Trial for the Further Development of Its Investigational Vaccine Enhancement Patch to Improve Pandemic Influenza Prevention in Collaboration With U.S. Department of Health and Human Services (HHS
... an H5N1 pandemic influenza outbreak with only a single
dose vaccine application
VIENNA and ... concomitantly, when combined with each other in a single
dose regimen. The trial will be conducted in the ... our goal to achieve full protection with only a single
dose plus patch this means an enormous logistical ...
New Study Evaluating the ADHD Medication VYVANSE(R) (lisdexamfetamine dimesylate) CII Demonstrated No Change in the Pharmacokinetic Profile of VYVANSE When Coadministered with Prilosec OTC(R) 40 mg (20 mg X 2), a Commonly Used Proton Pump Inhibitor (PPI)
... years. In the study, subjects were administered single
oral doses of VYVANSE 50 mg and ADDERALL XR 20 mg ... Prilosec OTC once daily for 14 days. Alternate single
doses of VYVANSE 50 mg and ADDERALL XR 20 mg were ... etiology of ADHD is unknown and there is no single
diagnostic test for this syndrome. Adequate ...
Pelleve Receives FDA Clearance for the Treatment of Mild to Moderate Facial Wrinkles
... based on clinical data demonstrating that a single
treatment with the high frequency radiowave ... Pelleve system, 83 women and 10 men were given a single
treatment with the Pelleve handpiece. The ... of the Pelleve Skin Tightening System. With a single
Pelleve treatment, over 87% of our patients ...
Intarcia Therapeutics, Inc. Announces Completion of Enrollment of ITCA 650 Phase 1b Study for the Treatment of Type 2 Diabetes
... for the full course of therapy with a single
insertion of the DUROS device on day 1 and ... in which longer durations of treatment with a single
ITCA 650 insertion will be evaluated. The DUROS ... can deliver up to a full year of therapy from a single
ITCA 650 insertion. The goals of the ITCA 650 ...
Prometheus and Rosetta Genomics Announce License and Collaboration Agreement
About miRview(TM) squamous
Using a single
microRNA, miRview(TM) squamous is designed to ... low accuracy. miRview(TM) squamous produces a single
objective measure that indicates whether a sample ... diagnosis is critical. Currently there is no single
diagnostic test that is conclusive for this ...
New Study Published in the Journal of Drugs in Dermatology Finds DOT Microablative CO2 Laser Optimum for Skin Rejuvenation
... in 4-5 treatments, the DOT technology can do in a single
treatment and results have been far superior to ... patients desiring significant effects from a single
treatment with minimal downtime. Additionally, ... 33-76 over a six-month period who underwent a single
laser resurfacing procedure with the DOT ...
Scientists Discover Why Teeth Form in a Single Row
... genetic forces determines why mammals develop a single
row of teeth, while sharks sport several, ... researchers discovered that turning off a single
gene in mice resulted in development of extra ... this pathway to restrict teeth within a single
One of the nation's top academic ...
Sequoia Pharmaceuticals Presents Proof of Clinical Concept of SPI-452, a Novel Pharmacokinetic Enhancer
study and a single
ascending-dose, first-time-in-human study ... Before administering SPI-452, subjects
received a single
dose of darunavir (600 mg), atazanavir (300 mg) ... (SQV). In part 1 of the study,
subjects received single
doses of SPI-452 (25 mg, 50 mg, 100 mg, 200 mg, ...
New Study Proves Multiple Births From IVF Can Be Avoided
... Shady Grove Fertility Center Proves that elective single
Embryo Transfer is Effective in Reducing Multiple ... )
The published study, " Elective single
embryo tra n sfer: A 6-year progressive implementation of 784 single
blastocyst transfers and the influence of payment ...
Medgenics Announces Positive Data From Phase I/II Clinical Trial of EPODURE Treatment of Anemia in Chronic Kidney Disease
... safety and efficacy for four months with
-- Institutional Review Board ... effectively for at least four months with a single
EPODURE treatment without the need for additional ... of hemoglobin levels for months from a single
treatment. Our results thus far appear to offer ...
Human Genome Sciences Begins Delivery of First-in-Class Anthrax Treatment to U.S. Strategic National Stockpile
... ABthrax (raxibacumab). The results showed that a single
dose of raxibacumab, administered without ... multiple animal models, which demonstrated that a single
dose of raxibacumab given prophylactically ... the anthrax vaccine, the protection afforded by a single
dose of ABthrax would be immediate following the ...
Modigene Announces Positive Results of Pilot Toxicity Study of Its Long-Acting Human Growth Hormone hGH-CTP
... - single
Injection in Primates Containing 1,000-Times the ... included a group of primates that received a single
injection of hGH-CTP containing a dose that was ... by these first data in primates showing that huge single
doses of hGH-CTP appear very safe," said Dr. Avri ...
Positive Phase II Study of Pacira's EXPAREL(TM) (DepoBupivacaine) in Hernia Repair Presented at the Postgraduate Assembly in Anesthesiology (PGA)
-- Pharmacokinetic findings showed that a single
infiltration of EXPAREL resulted ... and where the need for prolonged
analgesia via a single
administration can provide a significant ...
-- "A single
administration of DepoBupivacaine(TM) ...
USD 12.5 m Funding for the Development of Intercell's Vaccine Patch System for Pandemic Influenza From U.S. Department of Health and Human Services (HHS)
... under this HHS contract
demonstrated that a single
45-microgram dose of an injected H5N1 influenza
vaccine, coupled with a single
50-microgram Intercell patch was sufficient ... trial was one of the first to demonstrate
that a single
dose of Pandemic Influenza vaccine may meet the ...
New Keppra XR(TM) Data Highlight Its Role for Patients with Partial-Onset Seizures
... Emory University Hospital, USA
Dose Bioequivalence between Levetiracetam 2 x 750 ... to achieve a 1,500 mg dose. Results show that a single
dose of 2 x 750 mg Keppra XR tablets was bioequivalent to a 3 x 500 mg single
dose of Keppra XR in healthy adults, and that ...
Sunesis Pharmaceuticals Announces Presentation of Voreloxin Clinical Data in Patients with Acute Myeloid Leukemia at the 50th Annual Meeting of the American Society of Hematology
Phase 2 Study of Voreloxin as single
Agent Therapy (REVEAL-1 Trial)
Interim data ... esponse E valuation of V or E loxin in A m L ) single
agent Phase 2 trial show that voreloxin induces ... in the Phase 2 portion of this study.
agent cytarabine is the current treatment ...
Positive Phase II Study of Pacira's EXPAREL(TM) (DepoBupivacaine) in Total Knee Arthroplasty Presented at International College of Surgeons World Congress
... -- A Phase II dose escalation study of a single
intraoperative administration of EXPAREL(TM) ... for prolonged postoperative analgesia. Either a single
intraoperative administration of EXPAREL or ... (72 hours) postoperative pain relief in a single
administration. Currently available local ...
Bayer Announces Upcoming Presentations of Campath(R) and Leukine(R) Data at the 50th Annual Meeting of the American Society of Hematology
... Campath is indicated in the United States as a single
agent for the treatment of B-cell chronic ... anemia can occur in patients receiving Campath. single
doses of Campath greater than 30mg or cumulative ...
Campath is indicated as a single
agent for the treatment of B-cell chronic ...
Poniard Pharmaceuticals Announces Final Top-Line Results from Phase 1 Trial Demonstrating Positive Bioavailability with Oral Picoplatin
... solid tumor malignancies were randomized to a single
either intravenous (120 mg/m squared) or ... weeks later, they were crossed over to a second single
dose administered via the alternative ... part of the
trial, patients received only a single
oral dose of picoplatin (including
doses of 50 ...
Sunesis Pharmaceuticals Presents Clinical Trial Data of Voreloxin in Patients with Acute Myeloid Leukemia and Ovarian Cancer at the Chemotherapy Foundation Symposium
... from an ongoing Phase 2 trial demonstrate single
activity of voreloxin in advanced ... Phase 1 dose escalation trial of
voreloxin as a single
agent in acute leukemias (N=73) showed that ... oral
mucositis. The researchers concluded that single
agent activity in the
relapsed/refractory AML ...
Sequoia Pharmaceuticals Presents In Vitro and First-in-Human Data Supporting Further Development of SPI-256, a Novel Investigational Protease Inhibitor
... presented on 59 healthy volunteers who took a single
SPI-256 (150mg, 450mg, 600mg, 900mg, or ... in combination with 100mg of RTV or
received a single
dose of 1200mg of SPI-256 with a high-fat meal.
... over the
range of 150 to 1200mg. In addition, a single
dose of SPI-256 achieved
sufficient plasma ...
Rubicon Provides Genome Amplification for the Cancer Genome Atlas Project
... but enables
difficult clinical samples such as single
cells, plasma, serum and
formalin-fixed tissue to ... clinicians to
test for multiple analytes from a single
small sample, producing more
information from ... diagnostic applications,
including analysis of single
cells, formalin-fixed tissue and plasma.
Despite Advances in the Accuracy of CT Colonography in Detecting Polyps, Digestive Health Experts Urge Patients to Consider Risks and Realities
... pre-cancerous growths and removing them in a single
during colonoscopy," commented Dr. ... and breaking the sequence of polyp to
cancer in a single
diagnostic and therapeutic intervention, ... exposure, the ionizing radiation exposure
from a single
abdominal or chest CT may be associated with ...
Novare Announces Successful Series of Single Port Lap Band Procedures With RealHand(R) High Dexterity Instruments
... Hospital Center completes his 12th single
Procedure; Bariatric patients ... the successful completion of a series of single
procedures that results in reduced ... Teixeira. "By reducing the operative site to
incision in the belly button we are also able to ...
Algeta Reports Positive Headline Phase II Data on Pain Palliation With Alpharadin
... study was met. The study showed that even single
Alpharadin in patients with painful bone ... the palliative effects of four different single
dose levels of
Alpharadin in patients with bony ... has shown the beneficial
palliative effect of a single
dose of Alpharadin and that there is a ...
Alexza Reports 2008 Second Quarter Financial Results and Updates Development of Product Candidates
... in-clinic, multi-center randomized, double-blind, single
placebo controlled Phase 2a ... was to assess the safety and efficacy of a 1 mg single
of AZ-002 in treating a ... 1 clinical trial of 40
healthy volunteers, at a single
site, in a trial designed to assess the
First Molecular Tem-PCR Test to Identify Multiple Forms of Staph and MRSA Obtains CLIA Certificate
... multiple pathogens, both viral and bacterial in a single
less than four hours Tem-PCR can ... and community-acquired infections (CAI) in a single
Unlike hospital acquired MRSA ... both viral and bacterial, all in a single
Diatherix Laboratories Inc. is ...
Idenix Pharmaceuticals Advances HCV Discovery Program to Clinic
... healthy volunteers. This study will evaluate six single
doses of IDX184, ranging from 5 mg to 100 ... pocket of HCV
polymerase. IDX375 has exhibited single
nanomolar in vitro potency against
HCV genotype ... HCV protease. IDX136 and IDX316 have
nanomolar potency against HCV genotype 1a and ...
Novare Announces Completion of First Pediatric Single Port Spleen Removal Using RealHand(R) HD Instruments
... becomes 4th
surgical specialty to benefit from single
port surgery with RealHand HD ... the successful completion of the first pediatric single
splenectomy, using RealHand HD instruments. ... in the patient's belly button.
"It's called single
port surgery," said Dr. Dutta, "and it's the ...
Anesiva Commences Phase 2 Trial of Adlea(TM) in Arthroscopic Shoulder Surgery
... tolerability, efficacy,
and pharmacokinetics of a single
dose of Adlea administered via ... provide
pain relief for weeks to months after a single
localized treatment. Its
novel mechanism of ... Adlea has
been shown to reduce pain after only a single
administration for weeks to
months in multiple ...
Proteolix Initiates Phase 1b Clinical Trial of Carfilzomib in a Combination Regimen for Patients With Relapsed Multiple Myeloma
... activity, causing apoptosis in cancer cells.
agent Phase 1 studies carfilzomib has ... currently evaluating carfilzomib as a single
agent for the treatment of
multiple myeloma in ... that exhibits a high level of selectivity for a single
site in the proteasome with minimal cross ...
Eisai Provides Preliminary Efficacy Update On EORTC Phase III Trial of Dacogen(R) Versus Supportive Care in Patients With Myelodysplastic Syndromes
... on a North American,
multi-center, open-label, single
arm Phase II trial (DACO-020) in which
patients ... than 30 ongoing trials
with Dacogen either as a single
agent or in combination with other
therapies, ... DACO-020: This is a multi-center, open-label, single
arm Phase II study
of Dacogen in 99 patients with ...
Pressure Cycling Technology (PCT) Results in a Higher Yield of Proteins and in the Extraction of Proteins Not Previously Identified in Cancer, Stroke, and IVF Studies
... morbidity and mortality. To
combat this, more single
embryo transfers are needed. To this end, we ... selection and result in more live births
embryo transfers. These are very exciting ... and may not result in more live births
embryo transfers; that due to competitive ...
Results Published in the Journal 'Cancer' Demonstrate that Oral Talactoferrin Alfa is Active as Monotherapy in Previously Treated Patients with Metastatic Renal Cell Carcinoma
... this disease.
The talactoferrin monotherapy single
arm trial was conducted at six
leading U.S. ... in patients
with RCC are warranted either as a single
agent or in combination with one
of the newer ... monotherapy trial was an open label,
arm trial conducted at six leading U.S. sites. To ...
Trubion Pharmaceuticals Announces Presentation of Positive TRU-015 and SBI-087 Data at the 2008 Annual European Congress of Rheumatology Meeting
presented at the meeting demonstrated that a single
dose of SBI-087, a
next-generation Small Modular ... in a Phase I/IIa
study. Patients treated with a single
course of 5 mg/kg or higher in a
previously ... for
re-treatment. Patients who received a single
infusion of 5 mg/kg received a
single infusion of ...