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Sensory in Medical Technology

Scottsdale Facility to Be First in U.S. to Showcase True REST Technology

... for a technique that had previously been called sensory Deprivation (SD) or sensory Isolation. The use of sensory restriction as an intervention that alters human ...

Sangamo BioSciences Announces Presentation of Phase 1b ZFP Therapeutic Data at American Diabetes Association Meeting

... to transmit an applied electrical signal, in both sensory and motor nerves. Specifically, improvement in ... changes in neurological health. Quantitative sensory testing (QST) using the Vibratron II is used as a ... over time. NIS-LL includes measures of motor and sensory nerve heath as well as reflex testing and is a ...

Sangamo BioSciences Provides Update on Diabetic Neuropathy Clinical Programs

... moderate to severe diabetic peripheral sensory motor neuropathy (DN). The study is designed to ... CEO. "In addition to improvement in quantitative sensory testing (QST), three subjects with so-called ... has proven effective in protecting motor and sensory nerve function from disease-induced nerve damage. ...

Alseres Pharmaceuticals Announces 12 Month Interim Results from the Phase I/IIa Cethrin(R) Clinical Trial in Acute Spinal Cord Injury

... patients showed marked recovery of motor and sensory function after treatment as measured by a 2-grade ... the same 2-grade or better recovery of motor and sensory function. (Logo: ... A to E, with A being complete impairment with no sensory or motor function below the site of injury and E ...

NeurogesX Announces Preliminary Results from Second Phase 3 Clinical Trial in HIV-DSP

... patch drug candidate, in patients with HIV-distal sensory polyneuropathy (HIV-DSP). The prespecified ... HIV-DSP PHN is a painful condition affecting sensory nerve fibers. It is a complication of shingles, a ... factors: direct activation of cells known as sensory neurons by the HIV virus, the immune system's ...

Memory Pharmaceuticals & Roche Expand Development Program for MEM 3454 in Schizophrenia

... agonist, on two biomarkers of schizophrenia, P50 sensory gating and mismatch negativity, in patients with ... primary objective of the trial is to study P50 sensory gating and mismatch negativity as potential ... agonists, such as MEM 3454, in schizophrenia. P50 sensory gating and mismatch negativity are two ...

Alseres Pharmaceuticals Concludes Enrollment in the Cethrin(R) Phase I/IIa Clinical Trial in Acute Spinal Cord Injury

... measurements assess changes in subjects' sensory and motor functions, as well as overall recovery ... A to E, with A being complete impairment with no sensory or motor function below the site of injury and E ... E designate increasing levels of motor and sensory function. The subjects in the Cethrin Phase ...

Sangamo BioSciences Announces Completion of Enrollment of Phase 2 Clinical Trial of ZFP Therapeutic for Diabetic Neuropathy

... improvements in Quantitative sensory Testing (QST), clinically relevant improvements in motor and sensory nerve conduction velocities (NCV) and a trend ... with mild to moderate diabetic peripheral sensory motor neuropathy in the legs. A total of 102 ...

Neptune Industries Reports Favorable Phase II Trial Results on Ento- Protein(TM)

... not change their behavioral patterns. A panel of sensory experts that evaluated the trials indicated that ... State commented, "The results of our recent sensory evaluation comparing the taste, texture, aroma, ... feeding trials were very encouraging. A sensory panel of experts actually favored the flavor of ...

NeurogesX Completes Enrollment in Confirmatory Phase 3 Clinical Trial for Painful HIV Distal Sensory Polyneuropathy

... for the treatment of painful HIV-distal sensory polyneuropathy (HIV-DSP). NGX-4010 is a dermal ... and HIV-DSP PHN is a painful condition affecting sensory nerve fibers. It is a complication of shingles, a ... factors: direct activation of cells known as sensory neurons by the HIV virus, the immune system's ...

NeurogesX Completes Enrollment in Confirmatory Phase 3 Clinical Trial for Painful HIV Distal Sensory Polyneuropathy

... for the treatment of painful HIV-distal sensory polyneuropathy (HIV-DSP). NGX-4010 is a dermal ... and HIV-DSP PHN is a painful condition affecting sensory nerve fibers. It is a complication of shingles, a ... factors: direct activation of cells known as sensory neurons by the HIV virus, the immune system's ...

Continued Overall Survival Advantage Reported From Pivotal Trial of VELCADE(R) (Bortezomib) for Injection Based Therapy in Patients With Previously Untreated Multiple Myeloma

... are advised not to breastfeed while receiving VELCADE. Cases of severe sensory and motor peripheral neuropathy have been reported. The long-term outcome ... (52%), constipation (41%), peripheral neuropathy NEC (including peripheral sensory neuropathy and peripheral neuropathy aggravated) (39%), thrombocytopenia ...

Prolonged Progression-Free Survival Demonstrated by VELCADE(R) (Bortezomib) for Injection Based Induction Regimens in Transplant-Eligible Previously Untreated Multiple Myeloma Patients

... are advised not to breastfeed while receiving VELCADE. Cases of severe sensory and motor peripheral neuropathy have been reported. The long-term outcome ... (52%), constipation (41%), peripheral neuropathy NEC (including peripheral sensory neuropathy and peripheral neuropathy aggravated) (39%), thrombocytopenia ...

Novel VELCADE(R) (Bortezomib) for Injection Based Four-Drug Combination Was Well Tolerated In Previously Untreated Multiple Myeloma Patients

... are advised not to breastfeed while receiving VELCADE. Cases of severe sensory and motor peripheral neuropathy have been reported. The long-term outcome ... (52%), constipation (41%), peripheral neuropathy NEC (including peripheral sensory neuropathy and peripheral neuropathy aggravated) (39%), thrombocytopenia ...

New Eloxatin(R) (oxaliplatin injection) Prescribing Information in the U.S. Includes Six-Year Overall Survival Data

... was complicated by fever or infection in only 1.8% of cases. Peripheral sensory neuropathy ("tingling or numbness" in the fingers or toes) occurred in ... following treatment in most patients experiencing grade 3 peripheral sensory neuropathy. Patients treated with FOLFOX4 also reported nausea (73.7%), ...

Alseres Pharmaceuticals' Announces Expansion of the Cethrin(R) Acute Spinal Cord Injury (SCI) Phase I/IIA Clinical Trial

... suffered a complete thoracic or cervical injury (i.e. having no sensory or motor function below the level of the SCI). ASIA grades are designated ... normal. Grades 'B' through 'D' designate increasing levels of motor and sensory improvements. Interim results reported to date on the thirty-seven ...

NeurogesX Announces Positive Results from Second Phase 3 Clinical Trial in Postherpetic Neuralgia

... to 12 weeks. About PHN and HIV-DSP PHN is a painful condition affecting sensory nerve fibers. It is a complication of shingles, a second outbreak of the ... is caused primarily by three factors: direct activation of cells known as sensory neurons by the HIV virus, the immune system's fight against the infection, ...

NeurogesX Announces Preliminary Results of FDA-Requested Qutenza(TM) Study

... pain management therapies. Its initial focus is on chronic peripheral neuropathic pain, including postherpetic neuralgia (PHN), painful HIV-distal sensory polyneuropathy (HIV-DSP) and painful diabetic neuropathy (PDN). NeurogesX' late stage product portfolio is led by its product candidate Qutenza, a ...

NeurogesX Receives FDA Orphan Drug Designation for Qutenza(TM) for Treatment of Postherpetic Neuralgia

... pain management therapies. Its initial focus is on chronic peripheral neuropathic pain, including postherpetic neuralgia (PHN), painful HIV-distal sensory polyneuropathy (HIV-DSP) and painful diabetic neuropathy (PDN). NeurogesX' late stage product portfolio is led by its product candidate Qutenza, a ...

VA Studies Advanced Prosthetic Arm

... to movement impulses from the brain, shoulder joysticks or other conventional inputs. Frederick Downs Jr., director of VA's Prosthetic and sensory Aids Service who lost his left arm during combat in Vietnam, said he was "brought to tears" recently when the prosthetic arm allowed him to smoothly ...

Astrocytes Help Separate Man From Mouse

... Oberheim. "The view is slow to change, but scientists are coming around. Astrocytes are now acknowledged as active participants in brain function and sensory processing." The brain's two signaling systems - one composed of neurons, and one of astrocytes - complement each other, Nedergaard said. ...

NeurogesX Announces Publication of Phase 3 Data for QUTENZA(TM) (NGX-4010) in Postherpetic Neuralgia (PHN) by The Lancet Neurology

... pain management therapies. Its initial focus is on chronic peripheral neuropathic pain, including postherpetic neuralgia (PHN), painful HIV-distal sensory polyneuropathy (HIV-DSP) and painful diabetic neuropathy (PDN). NeurogesX' late-stage product portfolio is led by its product candidate Qutenza, a ...

Phase III Data Demonstrate Efficacy and Tolerability of Carisbamate as an Adjunctive Therapy for Partial Onset Seizures

... and may often be difficult to treat. Partial-onset seizures are most often characterized by simple or complex repetitive movements, but virtually any sensory or emotional symptom can also occur as part of a partial seizure, including complex visual or auditory hallucinations. There are two categories of ...

FDA Approves Tapentadol Immediate-Release Tablets for Relief of Moderate to Severe Acute Pain

... of Action Mu-opioid agonists are drugs that bind to and activate mu-opioid receptors in the central nervous system. These drugs modify sensory and affective aspects of pain, inhibit the transmission of pain at the spinal cord and affect activity at parts of the brain that control how pain is ...

New Evidence That Brain-Plasticity Based Training has Broad Impact: Improved Cognition in Boomers, Improved Motor Control in Older Adults

... through intensive brain plasticity-based training. Because the brain is plastic, some of this decline can be reversed by improving the sensory representations in the somatosensory cortex. The researchers developed a custom computer-based training program to improve motor control of ...

Concord Grape Juice Has No Significant Impact on Body Weight

... lifestyle and provided support for the Purdue University study. Study collaborators included James Hollis and Jenny Houchins of the Laboratory for sensory and Ingestive Studies, from the Department of Foods and Nutrition at Purdue University, and Dr. Jeffery Blumberg of the Antioxidants ...

New England Journal of Medicine Publishes Phase III Results of VELCADE(R) (Bortezomib) for Injection in Previously Untreated Multiple Myeloma Patients

... (including fatigue, malaise and weakness) (64%), nausea (55%), diarrhea (52%), constipation (41%), peripheral neuropathy NEC (including peripheral sensory neuropathy and peripheral neuropathy aggravated) (39%), thrombocytopenia and appetite decreased (including anorexia) (each 36%), pyrexia (34%), ...

NeurogesX Initiates Dosing in Phase 1 Clinical Trial for NGX-1998 Capsaicin Liquid Formulation

... pain management therapies. Its initial focus is on chronic peripheral neuropathic pain, including postherpetic neuralgia (PHN), painful HIV-distal sensory polyneuropathy (HIV-DSP) and painful diabetic neuropathy (PDN). NeurogesX' late stage product portfolio is led by its product candidate NGX-4010, a ...

NeurogesX Announces Publication of NGX-4010 Phase 3 HIV-Neuropathy Study Results in Neurology

... pain management therapies. Its initial focus is on chronic peripheral neuropathic pain, including postherpetic neuralgia (PHN), painful HIV-distal sensory polyneuropathy (HIV-DSP) and painful diabetic neuropathy (PDN). NeurogesX' late stage product portfolio is led by its product candidate NGX-4010, a ...

Multiple Clinical Trials of VELCADE(R) (Bortezomib) for Injection Based Therapies Demonstrate High Complete Remission Rates in Patients with Newly Diagnosed Multiple Myeloma

... and tumor lysis syndrome. Women of childbearing potential should avoid becoming pregnant while being treated with VELCADE. Cases of severe sensory and motor peripheral neuropathy have been reported. The long-term outcome of peripheral neuropathy has not been studied in mantle cell lymphoma. ...

VELCADE(R) (Bortezomib) for Injection Based Treatment Delivers Impressive Complete Response and Survival in Patients With Newly Diagnosed Multiple Myeloma

... and tumor lysis syndrome. Women of childbearing potential should avoid becoming pregnant while being treated with VELCADE. Cases of severe sensory and motor peripheral neuropathy have been reported. The long-term outcome of peripheral neuropathy has not been studied in mantle cell lymphoma. ...

NARSAD Researchers Identify Specific Genes and Family Traits Linked to Schizophrenia, Bipolar Disorder and Depression

... language, subtle anomalies involving the midline of the face, and difficulty filtering out noises and other irrelevant stimuli (a condition known as sensory gating). These traits, according to Dr. Levy, are much more common in families with schizophrenia. For example, idiosyncratic use of language (a ...

Discovering How Video Games Can Motivate Healthy Behaviors: More than $2 Million Awarded to 12 Research Teams Across U.S.

... attention training program. University of North Carolina at Chapel Hill, School of Public Health (Chapel Hill, NC) - Presence: Predicting sensory and Control Effects of Console Video Games in Young Adults will investigate motivations to expend energy during video game play for people aged 18 to ...

Lilly Submits Cymbalta(R) Supplemental New Drug Application for Chronic Pain to U.S. Food and Drug Administration

... daily treatment for an extended period of time. According to the International Association for the Study of Pain (IASP), pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage.(i) Chronic pain persists beyond ...

New Data Support High Complete Remission Rates With VELCADE(R) (Bortezomib) for Injection Based Therapies in Patients With Newly Diagnosed Multiple Myeloma

... and tumor lysis syndrome. Women of childbearing potential should avoid becoming pregnant while being treated with VELCADE. Cases of severe sensory and motor peripheral neuropathy have been reported. The long-term outcome of peripheral neuropathy has not been studied in mantle cell lymphoma. ...

Results of Phase 3 Study Show Tapentadol IR Relieves Acute Pain and Offers Favorable Gastrointestinal Tolerability Profile

... for chronic pain. Mu-opioid agonists are drugs that bind to and activate mu-opioid receptors in the central nervous system. These drugs modify sensory and affective (mood) aspects of pain, inhibit the transmission of pain at the spinal cord and affect activity at parts of the brain that control how ...

New Data From Phase 3 Study Suggests Tapentadol Immediate Release Effective for Acute Pain From Common Foot Surgery

... extended-release formulation for chronic pain. Acute pain is viewed as a complex, unpleasant experience with emotional and cognitive, as well as sensory features that occur in response to tissue trauma and is one of the most common reasons why patients seek medical attention. Common sources of acute ...

Gene Therapy Improves Vision in Patients with Congenital Retinal Disease

... and pathogenetic mechanisms involved in optic nerve disease and inherited retinal and macular degenerations, cell biology studies of photoreceptor sensory cilia, delineation of mechanisms underlying the light responses of rods and cones, gene discovery of complex and monogenic disorders, development of ...

EnVivo Pharmaceuticals Announces Initiation of Clinical Safety and Biomarker Study of Alpha-7 Nicotinic Agonist, EVP-6124, in Patients with Schizophrenia

... suppress this response by up to 80% while patients with Schizophrenia have decreased ability to suppress the response to a second stimulus. sensory gating abnormalities in Schizophrenia have been linked to an allele on chromosome 15, the gene locus for the alpha-7 receptor. Alpha-7 nicotinic ...

Perioperative Eloxatin(R)-Based Regimen Significantly Reduced the Risk of Relapse Versus Surgery Alone in Eligible Colorectal Cancer Patients with Initially Resectable Liver Metastases

... with post-operative chemotherapy include: neutropenia (Grade 3/4: 34.8%), leucopenia (Grade 3: 12.2%), other neurological toxicity (Grade 3: 12.2%), sensory neuropathy (Grade 3: 9.6%), thrombocytopenia (Grade 3: 7.0%), infection (Grade 3: 6.0%), hepatic (Grade 3: 5.2%), diarrhea (Grade 3: 5.2%), allergy ...
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(Date:9/30/2014)... (PCE) in drinking water may increase the risk ... new study led by a Boston University School ... in the journal Environmental Health , compared ... 1,766 women in Cape Cod, Ma., where water ... early 1980s by the installation of vinyl-lined asbestos ...
(Date:9/30/2014)... FRANKFURT. Truffles, along ... world. Because they grow underground, people use trained dogs or ... is not only of interest to gourmets. A group of ... University Frankfurt have discovered that the smell of white truffles ... truffle fruiting bodies. , White truffles from the Piedmont region ...
(Date:9/30/2014)... Researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich report that ... cells more sensitive to chemotherapeutic drugs. They have ... a new target for anti-tumor agents. , ... Professor Stephan Sieber of the Technische Universitt Mnchen ... a potential new weapon in the fight against ...
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(Date:10/2/2014)... Steven Reinberg HealthDay Reporter ... to a major highway may raise your risk for high ... 5,000 postmenopausal women, those who lived within 109 yards of ... developing high blood pressure than women living at least half ... this study highlight the importance of our physical environment on ...
(Date:10/2/2014)... Dennis Thompson HealthDay Reporter ... and the District of Columbia now have a total of ... that has been infecting children since the summer, U.S. ... virus have died in recent weeks, but it,s not clear ... those deaths, officials said. Health officials are also trying ...
(Date:10/1/2014)... An international team of scientists has shown that more ... treated with existing drugs. , The study found that ... cancers with a genetic mutation that is present in ... JAK inhibitors are currently used, or are in clinical ... and myeloproliferative disorders. , Bowel cancer is the second-most ...
(Date:10/1/2014)... Patients with increased inflammation, including those receiving cytokines ... of depression. For example, a 6-month treatment course ... infection causes depression in approximately 30% of patients. ... as fish oil, have a long list of ... disease and reducing triglyceride levels. These nutritional compounds ...
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