Isis Highlights New Data on Antisense Drugs to Treat Type 2 Diabetes and Obesity at ADA Scientific Sessions

... blood glucose levels and increase the body's sensitivity to insulin. Additionally, data was presented ... improvements in glucose tolerance and insulin sensitivity Significant reduction in plasma glucose ... (RBP4) caused significant improvements in insulin sensitivity with associated improvement in cardiac glucose ...

Metabolic Solutions Development Company Announces Preliminary Results from Phase IIa Clinical Trial

... Results show improved insulin sensitivity and lower glucose levels without the side ... its lead compound, MSDC-0160, can improve insulin sensitivity and lower blood glucose levels in humans without ... thiazolidinedione (TZD) can improve insulin sensitivity and lower glucose similar to a traditional TZD," ...

Pivotal Data Published For First Biomarker Combination Test to Determine Risk of Ovarian Cancer in Women Who Present With Pelvic Mass

... at identifying combinations of biomarkers to add sensitivity to the existing CA125 test, which is limited in its sensitivity and specificity as well as its ability to detect ... postmenopausal group the combination test had a sensitivity of 92.3%, a specificity of 74.7%, and a negative ...

New Mammography Technology Effective in Detecting Breast Cancer

... at Boca Raton Community Hospital in Florida. "The sensitivity of PEM is equal to or better than breast MRI, and ... lesions imaged, PEM detected 176 for an overall sensitivity rate of 93 percent. Fifteen percent were ductal ... now have a functional imaging approach with high sensitivity that compliments our current anatomic imaging ...

Data Reported at ICAAC Indicates Selzentry(TM) Phase III Treatment-Naive Trial Shows Increased Efficacy When Used With Enhanced Trofile(TM) Assay

... In June 2008 Monogram introduced an enhanced sensitivity version of the Trofile Assay, with 30-fold greater sensitivity to detect low-level X4 HIV compared to the ... the trial. The results obtained with the enhanced sensitivity version of the Trofile Assay were provided to ...

Walter Reed Evaluation Concludes FirstVue(TM) HBSAG Test is Preferred over Other Rapid Tests

... FirstVue(TM) HBSAG Test Found to Have Higher sensitivity and Specificity than Other Rapid HBSAG Tests ... based on an evaluation of published claims and sensitivity testing using HBSAG positive samples. Those tests ... that the FirstVue(TM) HBSAG test had the highest sensitivity (95.4%) and the highest specificity (99.7%) ...

Study Shows Benefits of a High Omega-3 Diet in Older Adults

... High Omega-3 Fat Intake Improves Insulin sensitivity and Reduces Inflammatory Markers, But Does Not ... that a diet high in omega-3 fat improves insulin sensitivity and reduces inflammatory markers, but does not ... fatty acids were measured on each diet. Insulin sensitivity was also assessed. The results showed that in a ...

First Cancer Diagnostic Test Based on Rosetta Genomics' Proprietary MicroRNA Technology Receives Regulatory Approval

... Squamous-Cell Carcinoma of the Lung With sensitivity of 96 Percent and Specificity of 90 Percent This ... CLIA Approved Test Which Leverages MicroRNAs' sensitivity as Biomarkers for Accurate Diagnosis of ... carcinoma of the lung with sensitivity of 96 percent and specificity of 90 percent. This ...

New Australian Technology: Detecting Breast Cancer With Hair

... or ultrasound achieved no greater than a 50% sensitivity at detecting breast cancer. A sensitivity of 78% was achieved when techniques were ... Fermiscan Test. Fermiscan's study demonstrated a sensitivity rate of 61% and an accuracy rate of 69% in ...

SuperGen's DNA Methyltransferase Inhibitor, S-110, Improves In Vivo Efficacy Profile of Decitabine

... Restored sensitivity to cisplatin observed in ovarian carcinoma ... xenograft models. Additionally, S-110 restored sensitivity to cisplatin in the ovarian cancer model. ... to explore its potential to enhance solid tumors' sensitivity to standard chemotherapy agents, including ...

Columbia University Medical Center and Rosetta Genomics Announce Columbia University's Submission of the First Cancer Diagnostic Test Based on Rosetta Genomics Proprietary MicroRNA Technology for Approval to the New York State Department of Health Clinica

... Squamous Cell Carcinoma of the Lung With sensitivity of 96 Percent and Specificity of 90 ... of the lung with specificity of 90 percent and sensitivity of 96 percent. This is the first test utilizing microRNAs' unique sensitivity and specificity as biomarkers that may offer a ...

Orion Genomics Announces the Discovery of Novel Breast Cancer Biomarkers

... Study Identifies Novel Biomarkers Displaying 90% sensitivity in Breast Cancer ... biomarker in the study, with a clinical sensitivity of 90% and a specificity of 96% for infiltrating ... breast cancer biomarkers exceeded the highest sensitivity previously reported for the stratification of ...

AspenBio Pharma Reports Strong Results with Appendicitis Triage Blood Test from Large Multiple Hospital Study

... with Test Results Showing sensitivity Level of 98%. CASTLE ROCK, Colo., Sept. 28 ... appendicitis." Continued Mr. Donnelly, "The sensitivity of this screen test was 98% in this large study. ... for emergency medicine. The high level of sensitivity also means that we could reduce the risk of ...

BSGI Posts Higher Sensitivity than Mammography or MRI for the Detection of Ductal Carcinoma In Situ

... Gamma Imaging (BSGI) provides higher sensitivity for the detection of Ductal Carcinoma In Situ ... of DCIS. Breast MRI has been shown to have a sensitivity of 73-89 percent for DCIS, but a limited ... 1.5-T system using a dedicated breast coil. The sensitivity of BSGI, mammography, and when performed, MRI ...

Alfacell Provides Shareholder Update

... would have on human tumors grafted onto these mice. Tumorgrafts parallel sensitivity and resistance in the clinic. The results showed Onconase has a documented ... complemented by most recent animal study in mice bearing tumors of varying sensitivity to Cisplatin and Carbo Platinum. In all of the animal models, the ...

Prometheus Announces New Findings Regarding Patients at Risk for Celiac Disease at DDW

... markers with a proprietary Smart Diagnostic Algorithm, which increases the sensitivity of the test by more than 25% when compared to single marker sensitivity values. About Celiac Celiac disease is an immune-mediated ...

Boehringer Ingelheim to Present New Phase II Clinical Data on Two Lead Oncology Compounds at ASCO 2009

... kinase (TK) domain of the EGFR gene are associated with an increased sensitivity to first generation EGFR TKIs.(6,7,8) The majority of patients who ... are common in lung cancers from 'never smokers' and are associated with sensitivity of tumors to gefitinib and erlotinib." Proc. Natl Acad. Sci. USA 101, ...

BioCryst Provides Peramivir Update and Reports First Quarter 2009 Financial Results

... has previously been demonstrated in various clinical studies. The sensitivity of the swine flu virus to peramivir has recently been reported by the CDC (1). Ten of the thirteen isolates of the H1N1 virus were tested for sensitivity to peramivir and all ten isolates were susceptible to peramivir. ...

AdvanDx Launches Fast, 90 Minutes Protocol for All CE-IVD Marked PNA FISH(R) Tests in Europe

... protocols to be 100% equivalent while maintaining the very high (>95%) sensitivity and specificity versus slower, conventional laboratory methods. Since ... 90 min. Turn-around Time and minimal Hands-on Time Close to 100% sensitivity and specificity versus conventional, slower laboratory methods ...

Cepheid Announces European Release of First On-Demand Molecular Test for Simultaneous Detection of Mycobacterium tuberculosis (TB) and Resistance to Rifampicin

... test, that has remained largely unchanged in its sophistication and sensitivity for over 100 years. The smear test has been proven to only detect around ... is much more sensitive." Sputum microscopy, which often delivers poor sensitivity in patients suffering from tuberculosis, is almost completely ineffective ...

Study Confirms: Your Hidden Food Allergies Are Making You Fat

... of Family Medicine (The Effect of The ALCAT Test Diet Therapy for Food sensitivity in Patient's With Obesity) that patients unable to achieve goal weight ... (CSS) is a life sciences company and the worldwide market leader in food sensitivity testing as the maker of The ALCAT Test. ALCAT identifies cellular ...

WaferGen and University of Texas Southwestern Medical Center Establish Biomarker Research Collaboration for SmartChip(TM) Real-Time PCR System

... capability and cost efficiencies of existing microarrays, with the sensitivity and accuracy of real-time PCR. Specifically, the SmartChip Real-Time PCR ... detection and sophisticated read-out options while assuring detection sensitivity and temperature uniformity across chips. About WaferGen ...

Rosetta Genomics Announces Commercial Availability of its First MicroRNA-Based Diagnostic Test; Will Host Teleconference to Discuss Launch of Future Tests

... appropriate targeted therapy for NSCLC." The test has a reported sensitivity of 97%, and a specificity of 91% in identifying squamous cell lung cancer. ... Officer at Rosetta Genomics. "This groundbreaking test, with its high sensitivity and specificity, will enable doctor and patient to adjust expectations, ...

Quark Pharmaceuticals Announces Publication of Study on Use of siRNA against Proprietary Target for Inhibiting Tumor Growth and Sensitization of Cancer Cells to Chemotherapy

... generates reactive oxygen species, suppresses tumor growth, and increases sensitivity to chemotherapeutic drug-induced cell death. Elena Feinstein, M.D., ... Suppression of Nrf2 effectively inhibited tumor growth and increased sensitivity to chemotherapeutic drug-induced cell death in the study. It is critical ...

First Published Study of New HPV Test for Developing Countries Shows High Accuracy in Predicting Cervical Disease

... cervical disease, also called CIN2+) was 41 percent. In contrast, the sensitivity of careHPV was 90 percent when samples of cervical cells collected by ... sensitive even than the newer, liquid-based Pap testing, for which the sensitivity was 85 percent when the sample was collected in the doctor's office. Pap ...

ASGE Encourages Patients to Speak to Their Doctor About Colorectal Cancer Screening Options

... patients. The study also showed that CT colonography had a lower sensitivity for smaller colorectal lesions of 6 to 9 mm in size. Researchers also reported: -- The sensitivity for the detection of adenomas or cancers greater than or equal to 5 ...

Despite Advances in the Accuracy of CT Colonography in Detecting Polyps, Digestive Health Experts Urge Patients to Consider Risks and Realities

... reduces colorectal cancer mortality. Because of its excellent sensitivity in detecting polyps and its potential for removing them and breaking the ... ACG has focused its evaluation on several pieces of evidence including: sensitivity for identification of polyps of various sizes, standards for polyp ...

CMS, Inc., an Elekta Company, Announces First Cancer Patients Treated With Monaco(TM) Radiation Treatment Planning System

... Chief of Medical Physics. "The multi-criteria optimization and the sensitivity analysis tools in the Monaco system also help reduce the time needed to ... new approaches that improve IMRT planning in the following ways: -- sensitivity Analysis tool that minimizes trial-and-error by guiding the decision ...

Markers in Blood and Spinal Fluid, and a New Imaging Agent, Show Promise for Early Detection of Alzheimer's

... 84%). This was true regardless of cognitive status, indicating excellent sensitivity of CSF AB42 for identifying the presence of brain amyloid, according to ... controlling for age and gender. The classification accuracy was 78%, the sensitivity was 80%, and the specificity was 77% for the combined model. "These ...

BD Announces CE Marking of a New Molecular Test to Diagnose Patients with Clostridium difficile Infections

... strains. It is the only CDI diagnostic test that combines high assay sensitivity with a rapid turnaround time of less than two hours, facilitating earlier ... GeneOhm Cdiff assay provides a simple and rapid stool test with excellent sensitivity and specificity that allows same-day identification of toxigenic ...

Novel Testosterone Gel Significantly Improves Insulin Sensitivity and Sexual Function in Hypogonadal Men With Type 2 Diabetes and Metabolic Syndrome

... topical, metered dose 2% testosterone gel, significantly improves insulin sensitivity and sexual function among hypogonadal men with Type 2 diabetes and/or ... endpoint by showing a statistically significant improvement in insulin sensitivity in testosterone treated patients at six and 12 months (p=0.05 and p=0.01, ...

New Global Survey Exposes Considerable Burden of Fibromyalgia Including Potential Economic Impact

... average, including chronic widespread pain, sleep disturbance, fatigue and sensitivity to touch. Many of the symptoms are described by patients as extremely or ... an abnormality in how the body responds to pain, particularly a heightened sensitivity to stimuli. A growing body of evidence suggests that alterations in the ...

Rosetta Genomics to Present Multiple Posters at the 44th Annual Meeting of the American Society of Clinical Oncology (ASCO)

... (CUP) MicroRNAs Objectively Identify Cancer Types With High sensitivity and Specificity and Could Revolutionize Diagnosis and Treatment of ... cancer sample based on the microRNA expression in the sample. The overall sensitivity of this classifier is approximately 85%, with two-thirds of the samples ...

Pharmacyclics Reports Multiple Presentations at AACR on Its HDAC and Selective HDAC Inhibitors

... 2008; both studies will incorporate the use of biomarkers to predict tumor sensitivity to drug treatment." Three studies were presented on Pharmacyclics' lead ... identifying biomarkers that may be useful in predicting the tumor sensitivity to treatment with PCI-24781. "These studies demonstrate that ...

New Gene Discovery Suggests Which Patients CTI's Brostallicin May Benefit

... Set Enrichment Analysis (GSEA) revealed unique associations between cells' sensitivity to brostallicin," and distinct sets of genes, "including ... 'hits' or targets were identified in the screen that modulate the cells sensitivity to brostallicin and represent unique and functionally based contexts of ...

Isis Announces $1.2 Million Award to Its Ibis Subsidiary to Expand Influenza Detection Capabilities and Enable Large-Scale Influenza Transmission Studies

... of closely related viral strains, and could do so with appropriate sensitivity and high-throughput efficiency." Respiratory diseases such as asthma, ... of the viral species and subtypes with greater than 97 percent sensitivity and specificity. ABOUT THE IBIS T5000 BIOSENSOR SYSTEM AND IBIS ...

Abbott Receives Supplemental FDA Approval for its Best-in-Class in Sensitivity RealTime HIV-1 Viral Load Test

... for Abbott's HIV-1 Viral Load Test, Which Surpasses Standard-of-Care sensitivity and is Unique in its Ability to Detect and Measure All ... few as 40 RNA copies per mL, surpassing the standard of care in diagnostic sensitivity of 50 copies per mL. Also, unlike other assays, the Abbott RealTime HIV-1 ...

Regular Yoga Practice Is Associated With Mindful Eating

... who are overweight. At the time, the researchers suspected that the weight-loss effect had more to do with increased body awareness, specifically a sensitivity to hunger and satiety than the physical activity of yoga practice itself. The follow-up study, published in the August issue of the Journal of ...

Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009

... targets demonstrating that reducing levels of these targets with antisense drugs can significantly lower blood glucose levels, increase the body's sensitivity to insulin, and reduce fat mass and body weight in animals. Isis partnered with non profit foundations to pursue new treatments ...

Injection Reverses Heart-Attack Damage

... Boston today is a 397-bed comprehensive center for pediatric and adolescent health care grounded in the values of excellence in patient care and sensitivity to the complex needs and diversity of children and families. Children ' s also is the primary pediatric teaching affiliate of Harvard Medical ...