Isis Highlights New Data on Antisense Drugs to Treat Type 2 Diabetes and Obesity at ADA Scientific Sessions
... blood glucose levels and increase the body's sensitivity
to insulin. Additionally, data was presented ... improvements in glucose tolerance and insulin sensitivity
Significant reduction in plasma glucose ... (RBP4) caused significant improvements in insulin sensitivity
with associated improvement in cardiac glucose ...
Metabolic Solutions Development Company Announces Preliminary Results from Phase IIa Clinical Trial
... Results show improved insulin sensitivity
and lower glucose levels
without the side ... its lead compound, MSDC-0160, can improve insulin sensitivity
and lower blood glucose levels in humans without ... thiazolidinedione (TZD) can improve insulin sensitivity
and lower glucose similar to a traditional TZD," ...
Pivotal Data Published For First Biomarker Combination Test to Determine Risk of Ovarian Cancer in Women Who Present With Pelvic Mass
... at identifying combinations of biomarkers to add sensitivity
to the existing CA125 test, which is limited in its sensitivity
and specificity as well as its ability to detect ... postmenopausal group the combination test had a sensitivity
of 92.3%, a specificity of 74.7%, and a negative ...
New Mammography Technology Effective in Detecting Breast Cancer
... at Boca Raton Community Hospital in Florida. "The sensitivity
of PEM is equal to or better than breast MRI, and ... lesions imaged, PEM detected 176 for an overall sensitivity
rate of 93 percent. Fifteen percent were ductal ... now have a functional imaging approach with high sensitivity
that compliments our current anatomic imaging ...
Data Reported at ICAAC Indicates Selzentry(TM) Phase III Treatment-Naive Trial Shows Increased Efficacy When Used With Enhanced Trofile(TM) Assay
... In June 2008 Monogram introduced an enhanced sensitivity
version of the
Trofile Assay, with 30-fold greater sensitivity
to detect low-level X4 HIV
compared to the ... the
trial. The results obtained with the enhanced sensitivity
version of the
Trofile Assay were provided to ...
Walter Reed Evaluation Concludes FirstVue(TM) HBSAG Test is Preferred over Other Rapid Tests
... FirstVue(TM) HBSAG Test Found to Have Higher sensitivity
than Other Rapid HBSAG Tests ... based on an evaluation of published claims
testing using HBSAG positive samples. Those tests ... that the FirstVue(TM) HBSAG test had
the highest sensitivity
(95.4%) and the highest specificity (99.7%) ...
Study Shows Benefits of a High Omega-3 Diet in Older Adults
... High Omega-3 Fat Intake Improves Insulin sensitivity
Inflammatory Markers, But Does Not ... that a diet
high in omega-3 fat improves insulin sensitivity
and reduces inflammatory
markers, but does not ... fatty acids were measured on each diet.
was also assessed. The results showed that in a ...
First Cancer Diagnostic Test Based on Rosetta Genomics' Proprietary MicroRNA Technology Receives Regulatory Approval
... Squamous-Cell Carcinoma of the Lung With sensitivity
of 96 Percent and Specificity of 90 Percent
This ... CLIA Approved Test Which Leverages MicroRNAs' sensitivity
as Biomarkers for Accurate Diagnosis of ... carcinoma of the lung with sensitivity
of 96 percent and
specificity of 90 percent. This ...
New Australian Technology: Detecting Breast Cancer With Hair
... or ultrasound achieved no greater than a 50% sensitivity
detecting breast cancer. A sensitivity
of 78% was achieved when techniques
were ... Fermiscan Test. Fermiscan's study demonstrated a sensitivity
of 61% and an accuracy rate of 69% in ...
SuperGen's DNA Methyltransferase Inhibitor, S-110, Improves In Vivo Efficacy Profile of Decitabine
... Restored sensitivity
to cisplatin observed in ovarian carcinoma ... xenograft
models. Additionally, S-110 restored sensitivity
to cisplatin in the
ovarian cancer model. ... to explore its
potential to enhance solid tumors' sensitivity
to standard chemotherapy
agents, including ...
Columbia University Medical Center and Rosetta Genomics Announce Columbia University's Submission of the First Cancer Diagnostic Test Based on Rosetta Genomics Proprietary MicroRNA Technology for Approval to the New York State Department of Health Clinica
... Squamous Cell
Carcinoma of the Lung With sensitivity
of 96 Percent and Specificity of 90 ... of
the lung with specificity of 90 percent and sensitivity
of 96 percent. This
is the first test utilizing microRNAs' unique sensitivity
as biomarkers that may offer a ...
Orion Genomics Announces the Discovery of Novel Breast Cancer Biomarkers
... Study Identifies Novel Biomarkers Displaying 90% sensitivity
in Breast Cancer ... biomarker in the study, with a clinical sensitivity
of 90% and a
specificity of 96% for infiltrating ... breast cancer biomarkers exceeded the
previously reported for the stratification of ...
AspenBio Pharma Reports Strong Results with Appendicitis Triage Blood Test from Large Multiple Hospital Study
... with Test Results Showing sensitivity
Level of 98%.
CASTLE ROCK, Colo., Sept. 28 ... appendicitis." Continued Mr. Donnelly, "The sensitivity
of this screen test was 98% in
this large study. ... for emergency medicine. The high
level of sensitivity
also means that we could reduce the risk of ...
BSGI Posts Higher Sensitivity than Mammography or MRI for the Detection of Ductal Carcinoma In Situ
... Gamma Imaging (BSGI) provides higher sensitivity
detection of Ductal Carcinoma In Situ ... of DCIS. Breast MRI has been shown to have a sensitivity
of 73-89 percent for
DCIS, but a limited ... 1.5-T system using a dedicated breast
coil. The sensitivity
of BSGI, mammography, and when performed, MRI ...
Alfacell Provides Shareholder Update
... would have on human tumors grafted onto these mice. Tumorgrafts parallel sensitivity
and resistance in the clinic. The results showed Onconase has a documented ... complemented by most recent animal study in mice bearing tumors of varying sensitivity
to Cisplatin and Carbo Platinum. In all of the animal models, the ...
Prometheus Announces New Findings Regarding Patients at Risk for Celiac Disease at DDW
... markers with a proprietary Smart Diagnostic Algorithm, which increases the sensitivity
of the test by more than 25% when compared to single marker sensitivity
Celiac disease is an immune-mediated ...
Boehringer Ingelheim to Present New Phase II Clinical Data on Two Lead Oncology Compounds at ASCO 2009
... kinase (TK) domain of the EGFR gene are associated with an increased sensitivity
to first generation EGFR TKIs.(6,7,8) The majority of patients who ... are common in lung cancers from 'never smokers' and are associated with sensitivity
of tumors to gefitinib and erlotinib." Proc. Natl Acad. Sci. USA 101, ...
BioCryst Provides Peramivir Update and Reports First Quarter 2009 Financial Results
... has previously been demonstrated in various clinical studies. The sensitivity
of the swine flu virus to peramivir has recently been reported by the CDC (1). Ten of the thirteen isolates of the H1N1 virus were tested for sensitivity
to peramivir and all ten isolates were susceptible to peramivir.
AdvanDx Launches Fast, 90 Minutes Protocol for All CE-IVD Marked PNA FISH(R) Tests in Europe
... protocols to be 100% equivalent while maintaining the very high (>95%) sensitivity
and specificity versus slower, conventional laboratory methods.
Since ... 90 min. Turn-around Time and minimal Hands-on Time
Close to 100% sensitivity
and specificity versus conventional, slower laboratory methods
Cepheid Announces European Release of First On-Demand Molecular Test for Simultaneous Detection of Mycobacterium tuberculosis (TB) and Resistance to Rifampicin
... test, that has remained largely unchanged in its sophistication and sensitivity
for over 100 years. The smear test has been proven to only detect around ... is much more sensitive."
Sputum microscopy, which often delivers poor sensitivity
in patients suffering from tuberculosis, is almost completely ineffective ...
Study Confirms: Your Hidden Food Allergies Are Making You Fat
... of Family Medicine (The Effect of The ALCAT Test Diet Therapy for Food sensitivity
in Patient's With Obesity) that patients unable to achieve goal weight ... (CSS) is a life sciences company and the worldwide market leader in food sensitivity
testing as the maker of The ALCAT Test. ALCAT identifies cellular ...
WaferGen and University of Texas Southwestern Medical Center Establish Biomarker Research Collaboration for SmartChip(TM) Real-Time PCR System
... capability and cost efficiencies of existing microarrays, with the sensitivity
and accuracy of real-time PCR. Specifically, the SmartChip Real-Time PCR ... detection and sophisticated read-out options while assuring detection sensitivity
and temperature uniformity across chips.
Rosetta Genomics Announces Commercial Availability of its First MicroRNA-Based Diagnostic Test; Will Host Teleconference to Discuss Launch of Future Tests
... appropriate targeted therapy for NSCLC."
The test has a reported sensitivity
of 97%, and a specificity of 91% in
identifying squamous cell lung cancer. ... Officer at
Rosetta Genomics. "This groundbreaking test, with its high sensitivity
specificity, will enable doctor and patient to adjust expectations, ...
Quark Pharmaceuticals Announces Publication of Study on Use of siRNA against Proprietary Target for Inhibiting Tumor Growth and Sensitization of Cancer Cells to Chemotherapy
... generates reactive oxygen species, suppresses tumor growth, and
to chemotherapeutic drug-induced cell death.
Elena Feinstein, M.D., ... Suppression of Nrf2 effectively inhibited tumor growth and
to chemotherapeutic drug-induced cell death in the
study. It is critical ...
First Published Study of New HPV Test for Developing Countries Shows High Accuracy in Predicting Cervical Disease
... cervical disease, also called
CIN2+) was 41 percent. In contrast, the sensitivity
of careHPV was 90
percent when samples of cervical cells collected by ... sensitive even than the newer, liquid-based
Pap testing, for which the sensitivity
was 85 percent when the sample was
collected in the doctor's office. Pap ...
ASGE Encourages Patients to Speak to Their Doctor About Colorectal Cancer Screening Options
... patients. The study
also showed that CT colonography had a lower sensitivity
colorectal lesions of 6 to 9 mm in size.
Researchers also reported:
-- The sensitivity
for the detection of adenomas or cancers greater than or equal to 5 ...
Despite Advances in the Accuracy of CT Colonography in Detecting Polyps, Digestive Health Experts Urge Patients to Consider Risks and Realities
... reduces colorectal
cancer mortality. Because of its excellent sensitivity
in detecting polyps
and its potential for removing them and breaking the ... ACG has focused its evaluation on several pieces of
evidence including: sensitivity
for identification of polyps of various
sizes, standards for polyp ...
CMS, Inc., an Elekta Company, Announces First Cancer Patients Treated With Monaco(TM) Radiation Treatment Planning System
... Chief of Medical
Physics. "The multi-criteria optimization and the sensitivity
tools in the Monaco system also help reduce the time needed to ... new approaches that improve IMRT planning in the following ways:
Analysis tool that minimizes trial-and-error by guiding
the decision ...
Markers in Blood and Spinal Fluid, and a New Imaging Agent, Show Promise for Early Detection of Alzheimer's
... 84%). This was true regardless of cognitive status,
indicating excellent sensitivity
of CSF AB42 for identifying the presence
of brain amyloid, according to ... controlling for age and gender. The classification accuracy was 78%,
was 80%, and the specificity was 77% for the combined
BD Announces CE Marking of a New Molecular Test to Diagnose Patients with Clostridium difficile Infections
... strains. It is the only CDI diagnostic test
that combines high assay sensitivity
with a rapid turnaround time of less
than two hours, facilitating earlier ... GeneOhm Cdiff assay provides a simple and rapid stool test with
and specificity that allows same-day identification
of toxigenic ...
Novel Testosterone Gel Significantly Improves Insulin Sensitivity and Sexual Function in Hypogonadal Men With Type 2 Diabetes and Metabolic Syndrome
... topical, metered dose 2% testosterone gel,
significantly improves insulin sensitivity
and sexual function among
hypogonadal men with Type 2 diabetes and/or ... endpoint by showing a statistically
significant improvement in insulin sensitivity
in testosterone treated
patients at six and 12 months (p=0.05 and p=0.01, ...
New Global Survey Exposes Considerable Burden of Fibromyalgia Including Potential Economic Impact
... average, including chronic widespread pain,
sleep disturbance, fatigue and sensitivity
to touch. Many of the symptoms
are described by patients as extremely or ... an abnormality in how the body responds to pain,
particularly a heightened sensitivity
to stimuli. A growing body of
evidence suggests that alterations in the ...
Rosetta Genomics to Present Multiple Posters at the 44th Annual Meeting of the American Society of Clinical Oncology (ASCO)
MicroRNAs Objectively Identify Cancer Types With High sensitivity
Specificity and Could Revolutionize Diagnosis and Treatment of ... cancer sample based on the microRNA expression in the
sample. The overall sensitivity
of this classifier is approximately 85%,
with two-thirds of the samples ...
Pharmacyclics Reports Multiple Presentations at AACR on Its HDAC and Selective HDAC Inhibitors
... 2008; both studies
will incorporate the use of biomarkers to predict tumor sensitivity
Three studies were presented on Pharmacyclics' lead ... identifying biomarkers that may be useful in predicting the tumor sensitivity
to treatment with PCI-24781.
"These studies demonstrate that ...
New Gene Discovery Suggests Which Patients CTI's Brostallicin May Benefit
... Set Enrichment Analysis
(GSEA) revealed unique associations between cells' sensitivity
brostallicin," and distinct sets of genes, "including ... 'hits' or targets were identified in the
screen that modulate the cells sensitivity
to brostallicin and represent
unique and functionally based contexts of ...
Isis Announces $1.2 Million Award to Its Ibis Subsidiary to Expand Influenza Detection Capabilities and Enable Large-Scale Influenza Transmission Studies
... of closely related viral strains,
and could do so with appropriate sensitivity
efficiency." Respiratory diseases such as asthma, ... of the viral species and subtypes with
greater than 97 percent sensitivity
and specificity. ABOUT THE IBIS T5000 BIOSENSOR SYSTEM AND IBIS ...
Abbott Receives Supplemental FDA Approval for its Best-in-Class in Sensitivity RealTime HIV-1 Viral Load Test
... for Abbott's HIV-1 Viral Load Test, Which Surpasses
and is Unique in its Ability to Detect and Measure All ... few as 40 RNA copies per mL, surpassing the
standard of care in diagnostic sensitivity
of 50 copies per mL. Also,
unlike other assays, the Abbott RealTime HIV-1 ...
Regular Yoga Practice Is Associated With Mindful Eating
... who are overweight. At the time, the researchers suspected that the weight-loss effect had more to do with increased body awareness, specifically a sensitivity
to hunger and satiety than the physical activity of yoga practice itself.
The follow-up study, published in the August issue of the Journal of ...
Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009
... targets demonstrating that reducing levels of these targets with antisense drugs can significantly lower blood glucose levels, increase the body's sensitivity
to insulin, and reduce fat mass and body weight in animals.
Isis partnered with non profit foundations to pursue new treatments ...
Injection Reverses Heart-Attack Damage
... Boston today is a 397-bed comprehensive center for pediatric and adolescent health care grounded in the values of excellence in patient care and sensitivity
to the complex needs and diversity of children and families. Children ' s also is the primary pediatric teaching affiliate of Harvard Medical ...