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Resolution in Medical Technology

Analysis of Ulcerative Colitis (UC) Time to Symptom Resolution Data from Pivotal Study of LIALDA(TM) (mesalamine) Presented at DDW

... -- A post hoc analysis showing time to symptom resolution data from a study (study 302) of Shire ... compared to placebo." Time to initial symptom resolution on LIALDA Poster Presentation: May 20, 2008, ... of study medication and the first day of symptom resolution (rectal bleeding or normalization of stool ...

Data Show FLECTOR(R) Patch Yields Significant Pain Reduction for Acute Strains, Sprains and Contusions

... Patch offered greater pain reduction and resolution of pain versus placebo patch. Results of another ... scale, "none" to "excellent"), and time to pain resolution (four scores less than or equal to two). ... FLECTOR(R) Patch patients also reached pain resolution three days sooner than those in the placebo patch ...

Studies Show Body Mass Index Has No Effect on Resolution and Healing of GERD Symptoms

... this week. One study, which evaluated symptom resolution in patients with non-erosive reflux disease, a ... showed that BMI had no significant effect on resolution of heartburn (P=0.9853) in patients treated with ... meeting include: Effect of Obesity on Symptom resolution in Patients with Gastroesophageal Reflux Disease ...

New Analysis of Study Data Shows That Asacol(R) (Mesalamine) Delivers Rapid Symptom Relief for Ulcerative Colitis Patients

... Symptom resolution results based on stringent endpoint of clinical ... as the first day of three consecutive days of resolution of both rectal bleeding and increased stool ... Mount Sinai Medical Center. "Sustained symptom resolution is what I want to provide my patients. Therefore, ...

New Analyses of Long-Term LIALDA(TM) (mesalamine) Data Presented at ACG

... of pivotal trials shows LIALDA offers initial resolution of UC symptoms within weeks Also being presented ... double-dummy studies. Time to Initial Symptom resolution with LIALDA for Active, Mild to Moderate ... for patients to experience initial symptom resolution of rectal bleeding and normalization of stool ...

Siemens Preclinical Imaging System Helps The Methodist Hospital in Houston Further Its Research Mission

... also delivers the industry's highest PET resolution and sensitivity and it boasts a suite of research ... eliminates the effect whereby the image loses resolution further out from the center of the field of view. ... detect peripheral lesions. This improved 2 mm resolution enables physicians to clearly visualize the ...

AstraZeneca Submits NDA for Low Dose Aspirin/Esomeprazole Combination Product

... (esomeprazole magnesium) NEXIUM 20 mg is indicated to maintain symptom resolution and healing of EE (controlled studies did not extend beyond 6 months), and ... for short-term treatment (4 to 8 weeks) in healing and symptomatic resolution of diagnostically confirmed erosive esophagitis (EE). NEXIUM should ...

Deer Farm Industry in Michigan Issues Statement on the Negative CWD Test Results at Kent County Deer Farm

... and the Department of Natural Resources to bring a swift and conclusive resolution to this difficult situation. Clearly more research is needed for a "live" ... as a legal and highly-regulated industry we are asking for a swift resolution to this issue and the lifting of the quarantine on more than 600 deer ...

Are PET Scans Beneficial During Cancer Diagnosis, Staging and Monitoring?

... combines a PET scan with computed tomography (CT) to capture higher resolution pictures of a patient's tissue. Because the PET images are low-resolution, oncologists combine the two to increase the image resolution and clarity of any "hot spots" showing up in the PET scan. However, ...

MacroChem Announces Phase 2 Data for EcoNail(R) in the Treatment of Onychomycosis

... in this trial who, if under my care, I would have considered to have shown resolution of their disease. These factors suggest that this new topical agent could ... this new consensus among experts in the medical community to better define resolution of onychomycosis, the negative mycology achieved together with the ...

Lupus Under the Spotlight: U.S. Congress Shows Support for Women's Health Issues

... and Department of Defense Health Programs. The House version of the resolution introduced by Rep. Maurice Hinchey (NY-D) is expected to pass this ... organ damage, and complications from the disease often prove fatal. The resolution properly recognizes that significant disparities exist in the prevalence ...

New Clinical Studies Confirm Mauna Kea Technologies' Cellvizio(R) GI in Range of Procedures

... to allow evaluation of morphological characteristics in 93% of sites; resolution was sufficient in 91%. Epithelial width could be measured in 94% and ... image quality one to eight minutes after fluorescein injection, with best resolution after five minutes. The authors conclude that these data may facilitate ...

Sirion Therapeutics Announces Positive Phase III Results for Difluprednate

... a more convenient dosing regimen and having the potential to offer rapid resolution of inflammation after ocular surgery would represent a meaningful advance ... formulation permits rapid penetration of the cornea, which promotes quick resolution of anterior chamber cells and flare. A Phase 3 program evaluating ...

Kosan's Second-Generation Hsp90 Inhibitor, Alvespimycin, Shows 42% Clinical Benefit in Phase 1 HER2-Positive Metastatic Breast Cancer Trial

... lapatinib and 3 prior trastuzumab-containing regimens) showed complete resolution of lung metastases by CT/PET with significant improvement in dypsnea ... for more than 19 months with evaluable disease had a near complete resolution of ascites and left pleural effusion at the end of cycle 2, and an 83% ...

Medigus and Tower Semiconductor Announce World's Smallest Medical Video Camera Based on Advanced CMOS Image Sensor

... in Medigus' manufacturing facilities. The CMOS imager offers a high performance product at a low cost and combines superb sensitivity, resolution and dynamic versatility, allowing customers a variety of potential medical applications in growing markets such as Gastroenterology, Natural Orifice ...

International Journal of Occupational and Environmental Health Features Discovery of Asbestos-Related Pain Origin from Scientists at the Karmanos Cancer Institute in Detroit

... pain which some patients experience," said Dr. Harbut. This new imaging approach involves enhancing images obtained on the 64-slice high resolution CT scan using the Vitrea(R) imaging software program by Vital Images. By using this imaging approach, Dr. Harbut was able to demonstrate that: ...

Thiarabine Demonstrates a Reduction of Both Inflammatory and Erosive Disease Parameters in Rheumatoid Arthritis

... severity at 20 mg/kg/day. In a therapeutic study comparing thiarabine to methotrexate, a commonly used clinical drug for RA treatment, high resolution 3-D images from an X-ray microtomograph were used along with histological scoring to evaluate joint and bone destruction. Thiarabine demonstrated ...

ThromboGenics' Microplasmin Phase III Program Progressing According to Schedule

... scheduled to take place after 50% of patients had been enrolled in one of the studies. The primary endpoint of both trials is the non-surgical resolution of focal vitreomacular adhesion within one month. Additional measures of efficacy and safety will also be assessed at various intervals over ...

Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression in Rheumatoid Arthritis Models by Selective Inhibition of the Immunoproteasome

... a complete amelioration of disease was achieved with a single dose. When compared to anti-TNF-a therapy (etanercept), PR-957 mediated a more rapid resolution of clinical symptoms, including joint inflammation, and was more effective than etanercept in a model of aggressive arthritis. These data ...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

... patients able to tolerate the reintroduction of Gleevec at a lower dose with or without concomitant corticosteroids or antihistamines following resolution or improvement of the bullous reaction. Consider potential toxicities-specifically liver, kidney, and cardiac toxicity, and immunosuppression ...

Type 2 Diabetes: An Epidemic Among America's Youth

... 1 and type 2 diabetes, diabetes complications, and tips on how diabetes patients can best prepare for disaster. A short, one page bio and high resolution photo of Francine R. Kaufman, MD, is available by clicking here . About AACE AACE is a professional medical organization with more ...

Taking a Hard-Line Approach to Cardiovascular Risks in the Diabetes Patient

... developing type 2 diabetes and cardiovascular complications. To download these recommendations click here . A short, one-page bio and high resolution photo of Howard S. Weintraub, MD, is available here . About AACE AACE is a professional medical organization with more than 6,200 ...

Oxygen Biotherapeutics, Inc. Receives Letter From FDA Outlining Path Forward to Resume Oxycyte Clinical Trials in TBI in U.S.A.

... is the company's perfluorocarbon (PFC) therapeutic oxygen carrier. The letter was in response to the company's request for formal dispute resolution that was submitted to the FDA Ombudsman's office. As a result, the Office of Blood Research and Review examined the reviewing division's decision to ...

Data from Phase 2 Study of Peramivir in Patients Hospitalized with Influenza Presented at the XI International Symposium on Respiratory Viral Infections

... 23.7 hours for peramivir 200 mg, 37.0 hours for peramivir 400 mg and 28.1 hours for oseltamivir (p=0.306). This exploratory endpoint was driven by resolution of fever. Viral shedding (time weighted change from baseline in viral titer) was reduced by a median of -2.0 logs for peramivir 200 mg, -2.1 logs ...

Savient Provides Update on Pegloticase BLA

... approval. Patients in the every 2 week dose regimen have demonstrated statistically significant clinical improvements including the reduction and resolution of gout tophi. Other statistically and clinically meaningful improvements included decreases in tender or swollen joint counts, reduction in flare ...

ThromboGenics Begins Phase III Program With Microplasmin for the Non-surgical Treatment of Back of the Eye Disease

... the United States (TG-MV-006) and 40 centres in Europe and North America (TG-MV-007). The primary endpoint of both trials is the non-surgical resolution of focal vitreomacular adhesion after one month. Additional measures of efficacy and safety will also be assessed at various intervals over six ...

US Testing Proves Glyc'n Go(TM) Increases NO in the Blood Stream

... in 60 count and 16-count individual serving packets. For more detailed information visit www.glycngo.com or call toll free 1-877-GLYCNGO. Hi resolution photos and images are available at http:// www.creativeimage.com/glycngopress ...

MRI Emerges As Vital Resource in Treatment of Back Pain

... roots, vertebrae, disks and blood vessels. With MRI there is no radiation risk to the patient. Computed tomography (CT) has also improved in resolution and scanning speed and is often the only imaging method available for patients with pacemakers, nerve stimulators, or those who suffer from ...

Video: Tasigna(R) Demonstrates Rapid Response as Initial Therapy in Life-Threatening Form of Leukemia

... patients able to tolerate the reintroduction of Gleevec at a lower dose with or without concomitant corticosteroids or antihistamines following resolution or improvement of the bullous reaction. Consider potential toxicities-specifically liver, kidney, and cardiac toxicity, and ...

MGuard(TM) Coronary Stent System Approved in Israel

... 60 planned) with acute STEMI who received the MGuard stent with no additional distal embolization or aspiration device. The primary endpoint is ST resolution and TIMI flow, and follow up is up to six months. The study's primary endpoints are complete resolution of ST-segment elevation and restoration of ...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

... patients able to tolerate the reintroduction of Gleevec at a lower dose with or without concomitant corticosteroids or antihistamines following resolution or improvement of the bullous reaction. Consider potential toxicities--specifically liver, kidney and cardiac toxicity, and ...

New Cancer Treatment Shrinks Pancreatic Tumor

... for some patients, based on this result and similar ones seen before the protocol's public availability. The tumor reduction correlated with resolution of the patient's symptoms of pain and digestive problems. "The cancer isn't gone," emphasized NeoPlas Innovation Director of Research Dr. Stephen B. ...

U.S. Navy and U.S. Army to Develop Dengue DNA Vaccine Formulated With Vical's Vaxfectin(R) Adjuvant

... was tested in humans. We are eager to support the application of our Vaxfectin(R) adjuvant in this important program and hope to advance toward resolution of this significant world health problem." NMRC scientists developed a DNA vaccine containing genes encoding the pre-membrane (prM) and envelope ...

Nerviano Medical Sciences Invited by EORTC-NCI-AACR to Present the State-of-the-Art of Aurora

... molecule was also observed in a patient with small cell lung cancer (SCLC) who, upon treatment, displayed a 77% reduction of one cancer lesion and resolution of a second one," concludes Dr. Colotta. Abstract no: 243, presented 10.15 hrs on Thursday 23 October, Plenary session 5 Information: ...

Epiphany Biosciences to Continue Phase 2 Shingles Study After Interim Analysis; Plans Follow-On Clinical Trial Studying Post-Herpetic Neuralgia (PHN)

... North America and uses an active comparator, valacyclovir. Outcomes assessed include various efficacy parameters including time to vesicular resolution and safety data collection. In addition to the Phase 2b zoster study, valomaciclovir will also be studied in a separate Phase 2 clinical trial as a ...

FluoroPharma Announces Positive Phase I Safety Results for BFPET(TM), Myocardial Perfusion Imaging (MPI) Tracer for Positron Emission Tomography (PET)

... are delighted to have reached this important clinical milestone as it addresses the need for innovative agents that draw on the inherently superior resolution of PET imaging compared to SPECT," said Dr. Kundakovic, President of FluoroPharma. "There is tremendous opportunity for BFPET, as a PET alternative ...

IDM Pharma Provides Update on Mifamurtide (L-MTP-PE) Regulatory Status Following June Meeting of European Committee for Medicinal Products for Human Use (CHMP)

... the Company's responses at its meeting in September 2008, when an oral explanation hearing will be held if required. The Company continues to expect resolution of the remaining issues regarding the Marketing Authorization Application (MAA) for L-MTP-PE in the third quarter. "The European review of L-MTP-PE ...

EPA Approves XDS-CALUX(R) as Alternate Dioxin Test Method 4435

... sensitivity and selectivity for quantifying dioxin-like chemicals. The XDS-CALUX(R) bioassay costs are 40%-70% lower than the traditional High resolution Gas Chromatography/Mass Spectrometry (HR GC/MS) that was the old singular analysis standard. Xenobiotic Detection Systems Method 4435 provides an ...

Rib-X Pharmaceuticals Renews Collaborative Agreement with the Medical Research Council

... structure and function for an additional year. Under the terms of the Agreement, Rib-X and the MRC will continue to jointly explore the high resolution crystal structure of the 70S ribosome. "Using information discovered about the ribosome during our first year of work with the MRC, Rib-X has been ...

Immunosyn Releases Wound Healing Photographs From the First Phase 'Proof of Concept Trial' in Europe for Treatment of Diabetic Ulcers With Biopharmeceutical SF-1019

... SF-1019 promotes wound healing and almost certainly induces growth factors. When systemically delivered (subcutaneously), SF-1019 has shown the resolution of long standing chronic lesions which is very impressive," stated Professor Angus Dalgleish, MBBS, BSc, MD, FRCP, RACP, FRCPath, FMedSci, Chief ...
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