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Replacement in Medical Technology

ThromboGenics and BioInvent Start Recruitment of Second 100 Patient Cohort in Phase II DVT Prophylaxis Study With TB-402

... as a single intravenous bolus injection post knee replacement surgery, and will enrol a total of 300 patients ... and 600,000 patients will undergo hip replacement in the U.S. if current trends persist.(2) Patients undergoing hip replacement or knee surgery are particularly at risk of ...

AcelRx Announces Positive Phase 2 Results from a Study of ARX-01 Sufentanil NanoTabs in Treating Post-Operative Pain

... in patients undergoing elective unilateral knee replacement surgery. Additionally, an open-label Phase 2 ... PCA System in patients undergoing unilateral knee replacement surgery. AcelRx Chief Medical Officer, ... commented, "The Phase 2 results from both knee replacement and major abdominal surgery studies demonstrate ...

Families of Spinal Muscular Atrophy Announces Latest Developments on Three SMA Drug Discovery Programs

... to correct gene splicing; and 3) Motor neuron replacement program at California Stem Cell and UCI. These ... trials of the drug candidate." Motor Neuron replacement Program: California Stem Cell (CSC) is ... the use of these cells in development of a cell replacement therapy for SMA Type I. Numerous ...

New Heart Ultrasound Research Reveals Life-Saving Treatment Alternatives and Advancements for Heart Patients

... be candidates for a new nonsurgical aortic valve replacement procedure . Transcatheter aortic valve replacement is a promising new treatment for patients with ... that transcatheter and surgical aortic valve replacement result in comparable improvements in radial ...

Celladon Corporation Announces Presentation of First-in-Human Gene Transfer to Treat Heart Failure at the 12th Annual Meeting of the American Society of Gene Therapy

... Profile and Biological Effects of SERCA2a Enzyme replacement SAN DIEGO, May 26 /PRNewswire/ -- Celladon ... that results from its genetically targeted enzyme replacement therapy for advanced heart failure, including ... represents the first-in-human trial of enzyme replacement therapy in heart failure using AAV and has ...

BioMarin Initiates Phase 1/2 Clinical Trial for GALNS for Morquio A Syndrome

... and manufactures two FDA-approved enzyme replacement therapies, one for the treatment of MPS I and one ... planned pre-clinical trials related to the enzyme replacement therapy for MPS IVA; the content and timing of ... agencies, particularly with respect to the enzyme replacement therapy for MPS IVA, and those factors detailed ...

Octogenarians: Not Too Old for Joint Replacement

... New study finds total knee replacement surgery can offer significant benefits to ... VEGAS, Feb. 26 /PRNewswire-USNewswire/ -- Knee replacement ( ... benefit both physically and socially from knee replacement surgery, also called total knee arthroplasty ...

When to Have That Joint Replacement?

... joint function before undergoing hip or knee replacement surgery, according to a new study presented today ... "Studies have shown that the timing of joint replacement surgery ( ... joint function of more than 3,500 hip and knee replacement patients based on physical exams and ...

Orthopaedic Surgeon Shortage Predicted Due to Soaring Joint Replacement Procedures

... ), the number of patients requiring hip or knee replacement surgery is likely to soon outpace the number of ... may not be able to receive it." Joint replacement ( ... innovations of the 20th century. Total joint replacement is a surgical procedure in which the patient's ...

American Academy Of Orthopaedic Surgeons 2009 Annual Meeting 'Highlights and Hot Topics'

... Academy of Orthopaedic Surgeons: Hip replacement ( ... Disappoints Those Who Expect a "Bionic" Hip replacement Using a common mechanism to score ... Botox Used To Treat Spasms After Hip replacement ( ...

Enobia Initiates Infantile Enzyme Replacement Trial for Rare Bone Disease

... was dosed. Enobia is investigating Enzyme replacement Therapy (ERT) with ENB-0040 for the treatment of ... is no approved treatment. "Our enzyme replacement therapy program for hypophosphatasia has ... is no currently approved drug therapy. Enzyme replacement Therapy for the treatment of hypophosphatasia is ...

Video: Prognosis Split for Hip Fracture and Hip Replacement in the Elderly

... patients can have positive outcomes following hip replacement surgery, but the extremely elderly hip fracture ... patients age 80 or older who underwent total hip replacement surgery. Researchers found that outcomes for total hip replacement in patients who were 80 or older at the time ...

Building a New and Better Ankle

... ) discusses the different types of total ankle replacement implants available now, both in the United States ... available to U.S. patients. While total ankle replacement offers patients more mobility and movement ... an ankle that is so unstable that total ankle replacement is not indicated," explains Cracchiolo. Signs ...

NJ-Based Surgeon Helps Pioneer Dramatic Advance in Treating Damaged Discs

... Total Disc replacement implant represents newest alternative surgical ... and no headaches. I'd recommend Total Disc replacement to anyone who was a candidate for it." In the ... vertebrae fused together. With the Total Disc replacement option, patients retain greater flexibility, and ...

PLC Systems Defers Pivotal Study of RenalGuard(TM) in the U.S.

... patients, where the careful monitoring and replacement of fluid losses helps avoid the risk of damage to ... kidney. Accurate and timely matching of replacement fluids is important in these instances in order ... The RenalGuard System, with its matched fluid replacement capability, is intended to minimize the risk of ...

Novel Testosterone Gel Significantly Improves Insulin Sensitivity and Sexual Function in Hypogonadal Men With Type 2 Diabetes and Metabolic Syndrome

... authorities later this year. The Testosterone replacement In hypogonadal men with either MEtabolic Syndrome ... 12 months (p <0.05). "These data tell us that replacement therapy for low testosterone in hypogonadal males ... the effect of daily transdermal testosterone replacement therapy in hypogonadal men with Type 2 ...

Edwards Lifesciences Announces First Implants in U.S. Study of Minimally-Invasive Pulmonic Valve

... valves or, as they age, their bioprosthetic replacement valves. This clinical study will enable ... application. In this transcatheter valve replacement procedure, the Edwards SAPIEN bovine pericardial ... the patient's pulmonary valve. The valve replacement is accomplished as a "beating heart" procedure, ...

Anesiva Announces Pivotal Phase 3 Clinical Trial of Adlea(TM) for Reducing Post-Surgical Pain Following Total Knee Replacement

... candidate, in patients following total knee replacement surgery, is underway. In September 2007, ... surgical site in patients undergoing total knee replacement surgery. Having completed enrollment of the ... on the 15 mg and placebo groups. "Total knee replacement is a commonly performed orthopedic surgery ...

Osteoarthritis: Which Treatments Work and Which Don't?

... -- These five recommendations include total joint replacement (96%); unicompartmental knee replacement (76%); osteotomy and joint preserving ... fusion as a salvage procedure when joint replacement had failed (69%). "Our goal was to make these ...

PLC Medical Systems Names Lead Investigators for Pivotal Trial to Evaluate RenalGuard System(TM) and RenalGuard Therapy(TM)

... is a fully-automated, real-time matched fluid replacement device intended for interventional cardiology and ... used. The real-time measurement and matched fluid replacement design of the RenalGuard System is intended to ... The RenalGuard System, with its matched fluid replacement capability, is intended to minimize the risk of ...

Facet Solutions' AFRS(TM) Demonstrates Biomechanical Advantages Over Dynamic Stabilization in Independent Testing

... of Toledo, demonstrated that the Anatomic Facet replacement System (AFRS(TM)) has shown ... stresses, and spinal stability of facet joint replacement versus dynamic stabilization devices. An ... the unconstrained range of motion, and the replacement of diseased bone with a cobalt chrome implant. ...

Facet Solutions Enjoys Continued Clinical Success With the Anatomic Facet Replacement System (AFRS(TM))

... utilizing the company's Anatomic Facet replacement System (AFRS(TM)) as part of an FDA approved IDE ... Trial. The AFRS(TM) is the first anatomic facet replacement device designed to provide patients with lumbar ... options," stated Dr. Regan. "Facet joint replacement utilizing the AFRS(TM) not only relieves low ...

Anesiva Defines Regulatory Pathway for Adlea with FDA

... of which has already been planned in total knee replacement surgeries -- and the second trial in bunionectomy ... total knee and another trial in total hip replacement surgeries. Anesiva expects to initiate ... two Phase 3 trials mentioned above for total knee replacement and bunionectomy surgeries. How Adlea May ...

Anesiva Initiates Phase 2 Trial with Adlea(TM) for Pain Relief Following Total Hip Replacement Surgery

... pain in patients who undergo total hip replacement surgery, also called Total Hip Arthroplasty ... application during the surgical procedure. "Hip replacement surgery can involve a long recovery time -- ... to reduce post-operative pain following total hip replacement surgery. Anesiva previously announced positive ...

Norditropin(R) Approved for Treatment of Children with Short Stature Associated with Turner Syndrome

... secretion of endogenous growth hormone and for replacement of endogenous growth hormone in adults with ... thyroid function tests and thyroid hormone replacement therapy should be initiated or adjusted ... may be unmasked requiring glucocorticoid replacement therapy. In addition, patients treated with ...

Norditropin(R) Approved for Treatment of Children with Short Stature Associated with Turner Syndrome

... secretion of endogenous growth hormone and for replacement of endogenous growth hormone in adults with ... thyroid function tests and thyroid hormone replacement therapy should be initiated or adjusted ... may be unmasked requiring glucocorticoid replacement therapy. In addition, patients treated with ...

The Lancet Publishes Major Phase 3 Study on Novel Oral Direct Thrombin Inhibitor

... therapy for patients undergoing total hip replacement surgery RIDGEFIELD, Conn., Sept. 13 ... therapy for patients undergoing total hip replacement surgery(1). The results from this study ... bleeding is the primary safety concern during hip replacement surgery, since major bleeding into the replaced ...

Anesiva Initiates New Phase 2 Trial of Adlea(TM) for Pain Relief Following Knee Replacement Surgery

... in patients undergoing total knee replacement surgery, also called total knee arthroplasty ... officer of Anesiva. "In total knee replacement surgery, up to 80 percent of these patients will ... About Total Knee Arthroplasty Total knee replacement (also known as total knee arthroplasty) ...

Spine Institute of Louisiana Offers Cervical Spine Motion Preservation as an Alternative to Fusion Surgery

... BENEFITS FROM FIRST EVER TWO-LEVEL TOTAL DISC replacement PERFORMED IN LOUISIANA ... performed the first ever two-level total disc replacement of the neck in the state of Louisiana. Spinal ... herniated, ruptured or slipped disc, involves the replacement of the diseased disc with an artificial disc. In ...

Estrogen Getting Cool Reception From Dermatologists for Mixed Results in Improving Appearance of Skin

... BOSTON, July 29 /PRNewswire-USNewswire/ -- For many women, hormone replacement therapy (HRT) can alleviate the physical symptoms associated with the ... mood swings and vaginal changes -- physicians often prescribe hormone replacement therapy (HRT) to boost the body's estrogen levels that drop dramatically ...

Prospective Clinical Advantages of Trabecular Metal(TM) Technology Highlighted in Comparative Study

... clinical study conducted by researchers at the Mayo Clinic and the Joint replacement Surgeons of the Indiana Research Foundation describes the low stiffness ... impact of temporarily suspending U.S. distribution of one of our key hip replacement products; product liability and intellectual property litigation losses; ...

Shoulder Surgery Doesn't Prevent Return to Sports

... findings that even an older individual who receives a total shoulder joint replacement can return to full participation within approximately six months of ... the ground or a fall during a tennis match. Contact sports after joint replacement surgeries are generally discouraged for the rest of an individual's life, ...

Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) for the Treatment of Fabry Disease

... stage and will enroll approximately 60 subjects who are naive to enzyme replacement therapy (ERT) or who have not received ERT for at least six months prior ... of Amigal in males and females with Fabry disease as compared to enzyme replacement therapy (ERT). The Agency agrees that the trial may enroll subjects ...

Scientific Data Relating to Cinryze(TM) Presented at 6th Annual C1 Inhibitor Deficiency Workshop

... in Pregnant Women An abstract entitled, 'Cinryze replacement Therapy in Hereditary Angioedema and Pregnancy' was presented by Dr. J.W. ... only if clearly needed; Six patients received 1000U of Cinryze replacement therapy 1-2 times per week as prophylaxis of HAE attacks during pregnancy. ...

AcelRx Initiates a Phase 2 Study to Evaluate Functionality of Its ARX-01 Sufentanil NanoTab PCA System

... for post-operative pain management in patients undergoing unilateral knee replacement surgery. AcelRx Chief Executive Officer, Thomas Schreck, commented, ... studies evaluating the efficacy and safety of Sufentanil NanoTabs in knee replacement and major abdominal surgery patients. Now with this third Phase 2 study ...

Melanoma and Pregnancy: What Every Woman Needs to Know About the Risks, Prognosis

... the effect of hormones received from external sources -- such as hormone replacement therapy (HRT) or oral contraceptive pills (OCPs) -- have found no ... followed 206 women diagnosed with localized melanoma who received hormone replacement therapy within five years of being diagnosed with melanoma. When compared ...

Facet Solutions, Inc. Expands U.S. Pivotal Study With Next Generation Implant System

... its Pivotal Study to 12 sites in the United States. The ACADIA(TM) Facet replacement Pivotal Study for the treatment of lumbar spinal stenosis utilizes the ... Dr. Dryer will be presenting on the lumbar kinematics of the ACADIA Facet replacement System on Thursday, April 30th at SAS. *Note: ACADIA(TM) is an ...

Oakwood Surgeons Perform World's First 3D Surgery Without Special Glasses

... Gold Seal of Approval from The Joint Commission for its hip and knee replacement program which includes the latest in minimally invasive technology, and a 14 bed sub-acute specialized unit for hip and knee replacement patients. To learn more about OHH please visit www.oakwood.org . ...

FDA Accepts Complete Response Submission to New Drug Application for NEBIDO(R)

... preparation available in the U.S. in the growing market for testosterone replacement therapies. NEBIDO is currently marketed by BayerSchering and its partners ... of whom fewer than ten percent are receiving treatment with testosterone replacement therapy. The market is highly under-treated and is expected to grow by ...

March 2009 Mayo Clinic Health Letter Highlights Knee Repair Surgery, Anxiety Disorder and Preventing Blood Clots

... certain cancers, advanced age, living in a nursing home, use of hormone replacement therapy, pregnancy, recent childbirth, a family history of DVT, and ... is in the same category, especially surgery that involves hip and knee replacement or is in the pelvic area. Many DVTs can develop and grow quite large ...
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(Date:7/11/2014)... from the Max Planck Institute for Medical Research in ... understanding photosynthesis, the process by which the Earth first ... and which is therefore crucial for all higher forms ... the first direct visualization of a crucial event in ... specific protein complex, photosystem II, splits water into hydrogen ...
(Date:7/11/2014)... marginal division of the striatum is also involved ... degree of substance P in the striatal marginal ... and his team, College of Biophotonics, South China ... substance P receptor, neurokinin 1 was highly expressed ... normal rats. Unilateral or bilateral injection of an ...
(Date:7/11/2014)... Rio de Janeiro, Brazil- In the brains of ... mechanism that allows an electric or chemical signal ... another. Chemical synapses, which are the most abundant ... inhibitory. Synapse formation is crucial for learning, memory, ... and inhibitory synapses critical for brain function. ...
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