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Repeat in Medical Technology

SYNTAX Analysis Finds Treatment With TAXUS(R) Express2(R) Stent System More Cost Effective Than Bypass Surgery in Patients With Complex Coronary Artery Disease

... the initial procedure, all hospitalizations, repeat procedures and medication. Although initial ... patients treated with CABG surgery. The rate of repeat revascularization was higher in the PCI group, although most procedures in the PCI group were repeat PCI, with only a small percentage requiring CABG ...

Journal of American College of Cardiology Article Reports Fewer Repeat Procedures With Boston Scientific's TAXUS(R) Liberte(R) Stent

... Stent had numerically lower incidences of repeat procedures to treat restenosis at two years as ... Stent, which had more than two times the risk of repeat procedures. The Swedish Coronary ... Liberte, which compared favorably in rates of repeat procedures to both 'olimus stents," said Donald ....

SYNTAX Analysis Finds Treatment With TAXUS(R) Express2(TM) Stents More Cost Effective Than Bypass Surgery in Many Patients With Complex Coronary Artery Disease

... complex disease -- and in whom the increase in repeat revascularization for PCI versus CABG was ... 12-month follow-up was the result of the cost of repeat revascularization procedures and higher long-term ... in patients treated with CABG. The rate of repeat revascularization was significantly higher in the ...

New England Journal of Medicine Publishes Results from Boston Scientific's Landmark SYNTAX(TM) Trial

... PCI patients were more likely to require a repeat revascularization (mostly additional PCI) than ... 12-month MACCE (all-cause death, stroke, MI and repeat revascularization), however, was significantly ... versus 12.4 percent, p=0.002), due to more repeat revascularization in the PCI arm (13.5 percent ...

TAXUS(R) Express(R) Stent Shows Similarly Low Re-Intervention Rates in Patients With Diabetes Compared to Non-Diabetics in Arrive Registry Program

... of diabetes as a risk factor for restenosis and repeat procedures in the patients studied," said Dr. ... are often at higher risk for adverse events and repeat stenting procedures," said Donald S. Baim, M.D., ... more likely than non-diabetic patients to require repeat procedures due to a higher incidence of ...

SCAI: CARDia Data Find Diabetic Patients With Complex Heart Disease Can Safely Choose PCI

... undergoing PCI or surgery, patients required a repeat procedure. The difference in repeat revascularization between PCI and bypass surgery ... the surgery patients are less likely to have repeat revascularization procedures this early, but it's ...

Large Study Gives Nod to Drug-Eluting Stents in Heart Attack

... appear to be any trade-off in increased risk of repeat MI or death," said Laura Mauri, MD, MSC, an ... rate of revascularization -- or the need for a repeat procedure to open the coronary arteries as a ... respectively, in the two groups (p=0.002), and repeat MI occurred in 9.5 percent and 11.0 ...

Drug-Eluting Stents Outperform Bare Stents in Heart Attack

... cardiac events (MACE) -- a combination of death, repeat heart attack, and repeat procedure to open the treated coronary artery -- ... by a 69 percent reduction in the need for a repeat procedure to reopen the treated coronary artery ...

Study Finds Repeated Episodes of Stent Thrombosis Common

... thrombosis with another stent hikes the risk of repeat blood clotting ... patients can expect to experience at least one repeat episode. According to the Dutch Stent Thrombosis ... analysis revealed three independent predictors of repeat stent thrombosis. Patients who had an additional ...

Surface Logix Achieves Objectives With SLx-2101 in Phase 2a Clinical Trial in Hypertension

... and effect on blood pressure in patients of repeat oral doses of SLx-2101 once daily for up to 14 ... of action, without showing accumulation upon repeat dosing. This allows for daily or on demand dosing ... of action, without showing accumulation upon repeat dosing. This superior product profile allows for ...

Treatment with PEGASYS(R)/COPEGUS(TM) Provides Hope for Hepatitis C Patients Whose Infection Did Not Initially Respond to Peg-Intron(R)/Ribavirin

... -- Roche today announced final results from the repeat study, which demonstrated that treatment with ... success with an initial course of therapy. repeat is an important study which adds significantly ... in REPEAT. "A significant finding from repeat is confirmation of the reliability of using a ...

Accent on Aesthetics Plastic Surgery Medical Center Selects Artefill to Meet Growing Patient Demand for a Longer Lasting Dermal Filler

... who are looking for a dermal filler that lasts longer and doesn't require repeat injections. We believe we have had great success with the product over the ... materials that are completely absorbed by the body over time and require repeat injections to maintain wrinkle correction. A skin test is required prior ...

Prometheus Announces New Findings Regarding Patients at Risk for Celiac Disease at DDW

... IBD Serology 7 tests within a two-year period. The overall rate of repeat testing ordered was only 2.2%. The results showed high concordance between the original and repeat tests; median changes in biomarker serum concentrations ranged between 2.2 ...

Boston Scientific Welcomes Publication of HORIZONS AMI Trial Results in New England Journal of Medicine

... adverse cardiovascular events (MACE), or its components, including death, repeat heart attack, stroke or stent thrombosis at one year. "The HORIZONS ... 8.0%, respectively, p=0.92), with comparable individual rates of death, repeat heart attack, stroke and stent thrombosis between the two groups through ...

Abbott's Market-Leading XIENCE V(R) Shows Increasing Clinical Advantages Over TAXUS(R) Express2(TM)/TAXUS(R) Liberte(TM) Between Two and Three Years

... with XIENCE V continue to experience fewer heart attacks, deaths or repeat procedures at the target lesion compared to patients treated with TAXUS ... "In the clinical outcomes that matter most, such as heart attack, repeat procedure at the target lesion or death, XIENCE V demonstrated a ...

Virtual Colonoscopies Show Value for Some Patients, But Polyps Will Be Missed

... is also insufficient to gauge the possible long-term effects of repeat radiation exposure from CT colonography at the regular recommended ... do it the same day as the colonography was performed, the patient must repeat the bowel preparation procedure for the follow-up colonoscopy. For ...

Study Demonstrates Restylane(R) Effect Lasted 18 Months in 97% of Patients With One Repeat Injection

... data show that Restylane (R) lasted 18 months in 97% of patients with one repeat injection. Restylane (R) is the only HA filler with an 18-month ... 97% of patients continued to show improvement in NLF correction with one repeat injection Correction with Restylane (R) lasted for 18 months, ...

Sangamo BioSciences Provides Update on Company's 2008 Progress and 2009 Objectives

... of nerve health at 180 days post treatment. -- Initiation of repeat dosing Phase 2 clinical trials of SB-509 in stem cell mobilization ... from this trial. -- Presentation of top line Phase 2 data from repeat dosing study of SB-509 in mild to moderate DN (SB-509-601) demonstrating ...

GlaxoSmithKline Announces New Drug Application and Phase III Results for Rezonic(TM)/Zunrisa(TM) (Casopitant)

... in the control population), with the clinical benefit maintained through repeat cycles.(1) Significant improvements were also observed in the complete ... The clinical benefit of all three dosing regimens was maintained through repeat cycles.(2) The most commonly reported all-cause adverse events by ...

Eisai's Commitment to Oncology Demonstrated by Clinical Data to be Presented at ASCO Annual Meeting

... the prevention of acute nausea and vomiting associated with initial and repeat courses of moderately and highly emetogenic cancer chemotherapy and for the prevention of delayed nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy. Aloxi is the first ...

Tailored Clopidogrel Dosing Improves PCI Outcomes

... month after PCI in the combined rates of heart attack, death, and need for repeat procedures to open the coronary arteries, with no increased risk of ... patients in the tailored therapy group had suffered a heart attack, needed repeat PCI or bypass surgery, or died, whereas 10 percent of patients in ...

TAXUS(R) Express(TM) Stent Shows Similarly Low Re-intervention Rates in Diabetic Patients Compared to Non-Diabetics in ARRIVE 1 and 2 registries

... the adverse effect of diabetes as a risk factor for restenosis and repeat procedures in the patients studied," said Dr. Morris of the Albert ... with diabetes are more likely than non-diabetic patients to require repeat procedures due to a higher incidence of restenosis following angioplasty ...

Evotec's EVT 101 Shown to Penetrate the Brain in Man and to Modulate Brain Activity During the Performance of Cognitive Tasks

... fMRI Study Completed and Reported Today Dosing in Four Week Higher repeat Dose Study Completed HAMBURG, Germany and OXFORD, England, March 28 ... Evotec has satisfactorily completed dosing of its four week higher repeat dose study conducted in France. Encouragingly, initial findings regarding ...

CeNeRx BioPharma Announces Successful Completion of Phase l Clinical Program for Novel Antidepressant Agent Tyrima(TM)

... of monoamine oxidase A. The Phase l program included acute dose, repeat dose and fed-fasted studies. The results of all studies were favorable, ... The Phase l program evaluated a range of Tyrima doses in 65 subjects. The repeat dose study results confirmed the positive findings of the acute dose trial ...

Trubion Pharmaceuticals Announces Presentation of Positive Data From Phase IIb and Re-treatment Studies With TRU-015 in Patients With Rheumatoid Arthritis

... mg. In addition, Trubion also announced presentation of data showing that repeat administration with TRU-015 was well tolerated and resulted in a ... a grade 3 adverse event on the day of infusion. Comparable Data Following repeat Administration (ACR Presentation 309) The objective of the re-treatment ...

Surgery More Likely Than Angioplasty to Relieve Pain for Patients With Coronary Artery Disease

... are more likely to get relief from painful angina and less likely to have repeat procedures if they get bypass surgery rather than balloon angioplasty with ... -- About 4 percent of patients who have bypass surgery undergo a repeat procedure within 1 year, and 10 percent within 5 years. The need is ...

Largest Study to Date Shows Significant Reductions in Risks of Blood Clots and Reintervention With CYPHER(R) Sirolimus-eluting Coronary Stent Compared to Taxus Stent

... percent reduction in blood clots (p=0.004) and a 55 percent reduction in repeat heart attacks (p=0.006) in patients who received the CYPHER(R) Stent ... patients presenting with a heart attack and patients being treated for repeat disease in a previously placed bare-metal stent, some of which are not ...

King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use

... of multiple daily doses of the active components of ACUROX(R) Tablets, and to determine if tolerance to the effects of niacin develops after repeat administration. Three groups of participants received different doses of niacin combined with oxycodone HCl, and the Side Effects and Symptoms ...

Investigational Genetic Test May Help Address Common Problems in Prostate Cancer Diagnosis

... be a useful biomarker for prostate cancer. Studies have shown that because PCA3 is highly specific for prostate cancer, it predicts the results of repeat biopsies more accurately than traditional prostate-specific antigen (PSA) testing.(5) Gen-Probe's PROGENSA(R) PCA3 assay, which has been ...

Peregrine Pharmaceuticals Reports Positive Preliminary Data From Phase II Bavituximab Lung Cancer Trial

... the combination of bavituximab, carboplatin and paclitaxel was completed. Eight of the 11 objective tumor responses were confirmed by at least one repeat scan no less than four weeks after the criteria for response were first met. Secondary objectives of the study include measuring time to tumor ...

AHRQ-Funded Study Finds Lower Risk of Death and Heart Attack in Patients With Drug-Coated Stent Implants Compared to Those With Bare Metal Stents

... University . The researchers found no significant differences in the percentages of drug-eluting and bare metal stent patients who required a repeat angioplasty or coronary artery bypass graft surgery (roughly 23 percent) and in the percentages of patients who suffered strokes or major bleeding ...

New Study Shows Probiotic Strain Effective in Improving Irritable Bowel Syndrome Symptoms

... most people with IBS." "We know from consumer data that people who try Digestive Advantage Irritable Bowel Syndrome are more likely to become repeat purchasers of the product than people who try 30 other of the most popular brands of digestive products sold in stores," said Marshall Fong, vice ...

DURECT Reports Positive Phase IIb Data from TRANSDU(TM)-Sufentanil Clinical Program

... that have involved over 300 patient exposures. These studies include evaluating wearing, pharmacokinetics, specialty populations, repeat applications, skin abrasions, drug interactions and dose conversions. In addition, a non-clinical package comprising multiple animal safety studies ...

Freezing Prostate Cancer Does a Man's Body Good

... approaches do, noted the professor at the University of Central Florida . "You can go home on the same day of the procedure, and you can repeat the treatment, if needed, in later years," said Onik. Additionally, Onik presented results of a 3-D biopsy method that provides superior information ...

Kensey Nash Announces IDE Submission for Cartilage Repair Device

... physicians perform approximately one million procedures each year to repair damaged articular cartilage in the knee and a majority of these are repeat procedures, illustrating the ineffectiveness of current therapeutic approaches. Over time, debilitating osteoarthritis may develop in the afflicted ...

Circulation Publishes Pivotal Two-Year Results On XIENCE V(TM) Drug Eluting Stent

... our earlier findings demonstrating the excellent angiographic and clinical results with the XIENCE V stent, resulting in fewer heart attacks and repeat reinterventions." The SPIRIT III trial demonstrated the following key results for XIENCE V at two years: -- A 45 percent reduction in ...

A Milestone in Cancer Genetics: deCODE Discovers First Common Genetic Variants Affecting the Risk of Many Types of Cancer

... bladder and prostate. Rs 2736089 is located in the gene encoding the human telomerase reverse transcriptase (TERT), which directs the addition of repeat DNA sequences to the ends of chromosomes. Importantly, the risk of these different cancers conferred by these two SNPs appears to be independent. ...

SARS Vaccine Achieves Neutralizing Responses in First U.S. Human Trial

... as well as induce antibody and T-cell immune responses. DNA vaccines contain no viral particles, are non-infectious, and can be administered on a repeat basis without unwanted immune responses. Additionally, DNA vaccines have the potential to achieve proof of concept more quickly and cost-effectively ...

Studies Examine Quality of Care for Hospitalized Sickle Cell Disease Patients and Effective Methods for Detecting Risk of Stroke in Children With This Disorder

... with normal TCD results (indicated by a cerebral blood-flow velocity of less than 170 cm/s in the internal carotid and middle cerebral arteries), repeat screening every three to six months in children with conditional TCD results (between 170 and 199 cm/s), and every one to four weeks in children with ...

GSK Reports PROMACTA(R) (eltrombopag) Significantly Increased Platelet Counts and Reduced Bleeding in Long-Term Study of Patients With Chronic ITP

... of PROMACTA, every 2 weeks during the dose adjustment phase, and monthly following establishment of a stable dose. If abnormal levels are detected, repeat the tests within 3 to 5 days. If the abnormalities are confirmed, monitor serum liver tests weekly until the abnormality(ies) resolve, stabilize, or ...
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