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Quantitative in Medical Technology

VisEn Molecular Imaging Technology Enables Key Insights Into Newly Discovered Biologic Pathway Published in SCIENCE

... Magnetic Resonance (MR) imaging combined with quantitative Fluorescence Molecular Tomographic (FMT) imaging. ... . In the in vivo data analysis, non-invasive, quantitative FMT imaging using novel fluorescent molecular ... today, and we are extremely pleased that our FMT quantitative in vivo imaging technology and activatable in ...

University of Michigan Study Shows SEQUENOM's MassARRAY Technology Identifies HPV Infections Missed by Standard Hybridization Test

... our results suggest that a type-specific, quantitative PCR-MS based test may be an important advance in ... and allelotyping, copy number variation analysis, quantitative gene expression analysis, quantitative methylation marker analysis, comparative sequence ...

Genomic Health Study Shows Breast Cancers in Men Display Very Similar Gene Signatures to Those in Women

... clinical utility of Onco type DX in providing quantitative information to help guide treatment decisions for ... of male breast cancer by standardized quantitative RT-PCR analysis: First large genomic study of 347 ... female breast cancers" (Abstract #549), analyzed quantitative gene expression by gender status in estrogen ...

VirtualScopics' Quantitative Imaging Provides Primary Endpoint in Cartilage Repair Pivotal Clinical Trial

... Pioneering study uses quantitative imaging endpoints from MRI analyses ... Inc. (Nasdaq: VSCP ), a leading provider of quantitative imaging for clinical trials, today announced that ... device (BST-CarGel(R)) and will now focus on quantitative measures to determine enhanced efficacy compared ...

Verification Studies of IntelligentMDx's Proprietary Molecular Diagnostic Assay Process Have Been Completed

... studies of the IntelligentMDx BK Viral quantitative Assay are complete. Under the verification ... reproducibility and robustness of the BK Viral quantitative Assay were determined. The data obtain agreed ... tech-to-tech testing. Analysis of the standard quantitative curves for each plate run (n=14) showed an ...

Genomic Health Announces Data Supporting Use of Oncotype DX(R) to Accurately Assess HER2 Gene Expression in Breast Cancer Patients

... results from two studies demonstrating that quantitative reporting for HER2 gene expression, as measured ... test by including single gene reporting for quantitative HER2 gene expression in all Oncotype DX reports ... -- 95 percent -- between central IHC and quantitative RT-PCR using Oncotype DX for determining HER2 ...

Sangamo BioSciences Announces Presentation of Phase 1b ZFP Therapeutic Data at American Diabetes Association Meeting

... to measure changes in neurological health. quantitative sensory testing (QST) using the Vibratron II is ... clinically relevant improvements in a number of quantitative measures of neurological health," said Edward ... to assess signs and symptoms of the condition. A quantitative neurologic exam such as NIS-LL is widely regarded ...

Multiple Studies Presented at San Antonio Breast Cancer Symposium Reinforce Clinical Utility of Oncotype DX(R)

... selection and patient satisfaction; reporting of quantitative ER and PR scores within the Oncotype DX report; ... cancer treatment decisions." Reporting of quantitative Estrogen Receptor and Progesterone Expression ... positive, tamoxifen-treated patients, only quantitative RT-PCR using Oncotype DX allowed for a risk ...

Pharsight Uses FDA Disease Model to Support Oncology Drug Development

... Cell Lung Cancer Expected to Inform quantitative Predictions for Experimental Cancer Treatment ... Strategic Consulting Services Group is using a quantitative disease model developed by the Food and ... with novel mechanisms. FDA has developed several quantitative drug-disease models based on the literature and ...

CRi Oosight(TM) Instrument Crucial in IVF Breakthrough Demonstrating a Correlation Between Non-Invasive Egg Metrics and Pregnancy

... factors to fertility and also validates the importance of good quantitative data as produced with the Oosight system. Such data are imperative if we ... for potentially harmful dyes or stains. In addition, these images contain quantitative data that indicate the relative order of structures within the spindle and ...

Genomic Health Announces Results of Initial Studies to Develop Predictive Tests for Targeted Therapies

... who did not exhibit the gene mutation (60 percent). Among all 226 samples, quantitative expression of 40 genes was significantly associated with disease control. ... progesterone receptor (PR) protein expression by IHC in a central lab and quantitative RNA expression by RT-PCR for 371 genes, including the current Oncotype DX ...

PTC Therapeutics Announces Data Supporting Cough Frequency as a New Outcome Measure in Evaluating Treatments for Cystic Fibrosis

... for CF, clinical development efforts would benefit from reliable quantitative endpoints that are clinically meaningful because they directly measure ... was designed to assess cough frequency as a measure of clinical benefit. quantitative measurement was achieved using a new technology, the VivoMetrics(R) ...

Memory Pharmaceuticals Highlights Progress with Key Programs at its R&D Day

... Memory Pharmaceuticals. "MEM 1414 produced a robust CNS signal in a human quantitative EEG study. In addition, using human whole blood assays, we have identified ... Pharmaceuticals reported the results of a clinical study of MEM 1414 on quantitative EEG (qEEG), a biomarker of central nervous system (CNS) activity. The ...

Genomic Health Announces Identification of Genes Associated With Colon Cancer Recurrence Across Multiple Studies

... Symposium, in Orlando, Florida. "These results allow us to conclude that quantitative gene expression using methods developed by Genomic Health can identify ... Oncotype DX for breast cancer." Both study reports used Genomic Health's quantitative RT-PCR to analyze RNA expression for 375 cancer-related and reference ...

Monogram Announces Posters to be Presented at the 30th San Antonio Breast Cancer Symposium

... Friday, December 14th, 2007, 7.00 am - 9.00 am CST Abstract # 2007: quantitative measurements of HER2 expression and HER2:HER2 dimerization identify ... # 2012: Characterization of a novel proximity immunoassay for the quantitative determination of HER2 protein expression and HER2 homodimerization in ...

Genomic Health Announces Eight Oncotype DX(R) Studies to Be Presented at 30th Annual San Antonio Breast Cancer Symposium

... Abstract #3028 Poster presentation: "Gene expression by standardized quantitative RT-PCR in the special histologic subtypes of estrogen receptor positive ... survival in a Kaiser Permanente population-based study: comparison of quantitative reverse transcriptase polymerase chain reaction and ....

Replikins LLC Finds West Nile Virus Replikin Count Has Reached Its Highest Recorded Value

... virus proteins, called replikins, which provide virus-specific advance quantitative warnings of rapid replication and the risk of epidemics. Replikins LLC has ... and past versions of the organism. (See http://www.replikins.com for quantitative data in Figures and press releases.) Earlier work by Replikins LLC on ...

Prospective Clinical Advantages of Trabecular Metal(TM) Technology Highlighted in Comparative Study

... around hip implants at an intermediate term (mean of 7.7 years) follow-up. Bone mineral density adjacent to acetabular implants was evaluated using quantitative computed tomography (QCT). The data demonstrated that stress-shielding around standard titanium cementless acetabular components continues well ...

AcelRx Announces Positive Phase 2 Results from a Study of ARX-01 Sufentanil NanoTabs in Treating Post-Operative Pain

... switched to IV PCA morphine, many requested that they be returned to study drug. To me, these patients' requests are as demonstrative as any more quantitative endpoint of the product's advantages from the patient perspective." The current data support the previously reported positive results for ...

ALP Life Sciences, LLC Announces Nanoveson(TM) Patent Filing and Whitepaper Availability on Proposed Therapy for Non-Alcoholic Fatty Liver Disease (NAFLD) and Comorbid Diseases

... industry in the area of drug metabolism testing. Research has demonstrated that enterohepatic circulation is the mechanism that maintains quantitative whole body homeostasis of arachidonic acid. There is extensive research focused on blocking arachidonic acid metabolism along cytochrome P450, ...

vProtect(TM) Luminal Shield Stabilizes Vulnerable Plaque

... gently expanding over time. Imaging studies revealed that the residual stenosis in the area of the lesion improved from 30% to just 5% (measured by quantitative Angiography). The Shield was covered by a thin layer of healthy tissue with an average thickness of 80 - 110 microns. "These results are comparable ...

Celladon Corporation Announces Presentation of First-in-Human Gene Transfer to Treat Heart Failure at the 12th Annual Meeting of the American Society of Gene Therapy

... represents the first-in-human trial of enzyme replacement therapy in heart failure using AAV and has demonstrated acceptable safety and produced quantitative evidence of biological activity across a number of parameters important for assessing heart failure. Celladon is testing the hypotheses that ...

Swine Flu (H1N1) Infectivity to Increase Markedly and Lethality to Remain Low According to Latest Replikin* Peptide Genomic Data

... the infectivity of the H1N1 virus will increase markedly, while its lethality will remain relatively low for the immediate future. The company's quantitative analysis of the most recent sequence data available on PubMed, a standard scientific repository for published papers, showed an increase of 46% in ...

No Causality Found Between Black Cohosh and Liver Problems

... Dr. Naser, Head of Drug Safety at Schaper & Brummer GmbH & Co. KG. This re-evaluation of case reports applied the latest qualitative and quantitative causality assessment and diagnostic algorithm of the Council for International Organizations of Medical Sciences (CIOMS). "Due to incomplete ...

Cynosure Announces Presentation of Favorable Results from Post-Marketing Studies of Smartlipo MPX

... skin tightening was 62% with Smartlipo MPX compared with a 5% improvement on the side treated with liposuction. "This is the first head-to-head quantitative study comparing the efficacy of the Smartlipo MPX workstation with that of liposuction, and the first study to illustrate the effects of subdermal ...

New Report by BioTrends Research Group to Highlight the Launch of ULORIC(R) (febuxostat)

... that has been approved in over forty years. LaunchTrends(TM): Uloric (R) is a three wave primary market research study that consists of a quantitative on-line survey and qualitative telephone interviews. In total, 300 Rheumatologists and Primary Care Physicians will participate in the research. ...

Infant Blood May Provide Insights into Diseases Present at Birth

... resource," said James Resau, Ph.D., distinguished scientific investigator, deputy director for special programs, and director of the Division of quantitative Sciences at VAI. "Imagine testing blood from nearly the entire population of U.S. infants and using the data for the retrospective study of disease. ...

Rosetta Genomics Announces Commercial Availability of its First MicroRNA-Based Diagnostic Test; Will Host Teleconference to Discuss Launch of Future Tests

... for differentiation of NSCLC patients, which is based on our proprietary microRNA technology. miRview(TM) squamous offers physicians a standardized, quantitative diagnostic tool which may assist in determining the appropriate targeted therapy for NSCLC." The test has a reported sensitivity of 97%, and ...

IBT Laboratories Expands its Menu of Tests for Immune Deficiency

... health outcomes." The MBL pathway is one of the most important components of the innate immune system. IBT has developed a unique and quantitative serum test (MBL Pathway Function Test) to evaluate the effectiveness of this pathway. This test will be particularly useful to assess children with ...

TorreyPines Therapeutics Muscarinic Agonist NGX267 Meets Primary Endpoint in a Phase II Clinical Trial in Patients with Xerostomia

... significant compared to placebo for each of the three doses of NGX267. Results of the 8-item patient self-assessment correlated with the quantitative results of salivary production. At the 15 mg and 20 mg doses, statistically significant differences compared to placebo were demonstrated in a ...

GeneThera Announces it is Set to Begin Commercial Testing for Johne's Disease as Soon as January, 2009.

... This also facilitates the quantization of the DNA. Not only can one tell instantly "what" DNA is present in the sample but also "how much." quantitative PCR (Q-PCR), as this technique is known, is used to measure the quantity of a PCR product (usually in a real-time PCR procedure). It is the method of ...

APTA Supports Surgeon General's 'Call to Action' to Prevent Deep Vein Thrombosis and Pulmonary Embolism

... for physical therapy news and information. Notes: 1) Aryal KR, Al-Khaffaf H. Venous thromboembolic complications following air travel: what's the quantitative risk? A literature review. Eur J Vasc Endovasc Surg. 2006;31:187-99. 2) Scurr JH, Machin SJ, Bailey-King S, Mackie IJ, McDonald S, Smith ...

AstraZeneca and Targacept Announce Top-Line Results from Phase IIb Study of AZD3480 in Alzheimer's Disease

... of clinician assessment of change in patients' behavior and ability to function, and MMSE (Mini Mental State Examination, a 30-point scale), a quantitative cognition scale commonly used by neurologists in a clinical setting. Of the three AZD3480 doses, the middle dose performed best on both measures (0.5 ...

96-Well Filtration Plate From Varian, Inc. Improves Sensitivity and Precision for Trace Bio-Analysis by LC/MS

... from biofluids. It is intended for use by analytical chemists in the pharmaceutical and life science industries performing quantitative and qualitative analyses of drugs in biofluids. In applications such as drug screening and monitoring in early discovery, pre-clinical and clinical ...

CRi Announces New Maestro(TM) EX In Vivo Imaging System with Improved Performance and an Affordable Price

... times or increased spectral resolution for enhanced separation of similar fluorescent labels. Accurate spectral detection is essential for quantitative signal unmixing. Patent-pending Maestro software tools complement the improved optical capabilities of the Maestro EX by ensuring accurate and ...

NewCardio Announces Positive Results From Third Clinical Validation Study

... accuracy and precision of clinical trials. NewCardio believes QTinno(TM) is equal to the best manual assessments and is able to provide high-quality quantitative data from a broad range of difficult-to-read ECGs. About NewCardio, Inc. NewCardio is a cardiac diagnostic and services company focused on ...

Amicus Therapeutics Announces Second Quarter 2008 Financial Results

... basis. Amicus' evaluation of whether to exclude an item for purposes of determining its non-GAAP financial measures considers both the quantitative and qualitative aspects of the item, including, among other things (i) its size and nature, (ii) whether or not it relates to its ongoing ...

Cara Therapeutics Announces Successful Completion of Phase I Clinical Trial of Novel Analgesic, CR845

... infusion, and resulted in plasma levels of CR845 expected to be associated with clinical analgesic activity. In addition, CR845 infusion triggered a quantitative endocrine biomarker of peripheral kappa opioid receptor activation at the lowest dose tested. The Phase Ia single-center clinical trial evaluated ...

Current and Emerging Drugs Continue to Struggle for Patient Share in the Treatment of Major Depressive Disorder

... combines market forecasts with clinical and commercial end points to assess market share projections in 35 indications. These outputs are driven by quantitative and qualitative primary research. DecisionBase 2008 provides detailed market share, patient share, and price-per-day projections for emerging drugs ...

AlphaDetail AlphaPulse(TM): Most Practicing Physicians React Positively to FDA Panel's Recommendation for Additional Cardiovascular Safety Trials for New Diabetes Medications.

... have an unparalleled commitment to our clients. We are a full-service primary market research firm, with a particular emphasis in large and complex quantitative studies for the global healthcare community. AlphaDetail is built on one of the industry's strongest foundations that includes a large team of ...
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(Date:8/28/2014)... Scientists have identified the developmental on-off switch for ... more than two-thirds of the world,s naturally derived antibiotic ... see whether it is possible to manipulate this switch ... The study, appearing August 28 in Cell , ... called cyclic-di-GMP and a larger protein called BldD ultimately ...
(Date:8/28/2014)... FASEB MARC (Maximizing Access to Research Careers) Program ... American College of Sports Medicine,s Conference on Integrative ... Miami, Florida. These awards are meant to ... scientists from underrepresented groups into the mainstream of ... participation of young scientists at the American College ...
(Date:8/28/2014)... the most commonly diagnosed learning disability in the ... occurs when the regions of the brain that ... use of non-invasive functional neuroimaging tools has helped ... However, most prior work has focused on only ... gap in our understanding of how multiple brain ...
Breaking Biology News(10 mins):Small molecule acts as on-off switch for nature's antibiotic factory 2Small molecule acts as on-off switch for nature's antibiotic factory 3Dyslexic readers have disrupted network connections in the brain 2
(Date:8/29/2014)... August 29, 2014 Today, Progene reaches another ... with not only a healthcare network , but also ... “We started the network a few weeks ago. Today, ... Michael Lee of Progene. , The network adds an ... care of our customers before and after they make a ...
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Breaking Medicine News(10 mins):Health News:Progene Is Doctor Recommended Nationwide 2Health News:Progene Is Doctor Recommended Nationwide 3Health News:North York Dental Provides Dental Services to Busy Professionals 2Health News:Charity Event to Raise Awareness and Donations for the ALS Foundation 2Health News:Top10BestSEOHosting.com: Bluehost, Arvixe, and Hostgator Are the Best Windows Web Hosting from the USA in 2014 2Health News:The Law Office of Melinda J. Helbock A.P.C. Comments on Zoloft Birth Defect Lawsuit 2
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