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Pump in Medical Technology

New Study Evaluating the ADHD Medication VYVANSE(R) (lisdexamfetamine dimesylate) CII Demonstrated No Change in the Pharmacokinetic Profile of VYVANSE When Coadministered with Prilosec OTC(R) 40 mg (20 mg X 2), a Commonly Used Proton Pump Inhibitor (PPI)

... (lisdexamfetamine dimesylate) CII with the proton pump inhibitor (PPI) Prilosec OTC(R) 40 mg (20 mg X ... is the first to evaluate the impact of a proton pump inhibitor on the amphetamine pharmacokinetics of ... of Americans. Prilosec OTC and other proton pump inhibitors reduce the acidity (increase the pH) ...

Terumo Heart, Inc. Reaches Clinical Milestone as the 100th Patient Worldwide Receives the DuraHeart(TM) Left Ventricular Assist System

... LVAS is the first, third-generation rotary blood pump designed for long-term patient support that incorporates a centrifugal flow rotary pump with an active magnetically levitated impeller ... The DuraHeart LVAS features a small centrifugal pump that is implanted in a small pocket created ...

Study Data Show Positive European Experience With DuraHeart Left Ventricular Assist Device for Advanced Stage Heart Failure Patients

... System is the first third-generation rotary blood pump designed for long-term patient support that incorporates a centrifugal flow rotary pump with an active magnetically levitated impeller ... in Japan. The DuraHeart System features a small pump that is implanted in a pocket created in the ...

David Feldman, M.D. Appointed Co-Principal Investigator of DuraHeart(TM) Left Ventricular Assist System U.S. Clinical Trial

... the surgical procedure, and the only centrifugal pump with an actively levitated impeller, which is ... The DuraHeart System features a small pump that is implanted in a pocket created in the abdomen. When the pump is activated, the impeller position is precisely ...

Terumo Heart, Inc. Reports Clinical Progress in the DuraHeart(TM) U.S. Pivotal Trial as NewYork-Presbyterian Hospital/Columbia University Medical Center Implants First Patient

... System is the first third-generation rotary blood pump designed for long-term patient support that incorporates a centrifugal flow rotary pump with an active magnetically levitated impeller ... Japan. The DuraHeart System features a small pump that is implanted in a pocket created in the ...

FDA Approves Rapid-Acting Insulin Apidra(R) for Treatment of Children with Diabetes

... can also be used in insulin infusion pump therapy for blood sugar control. About the ... a longer-acting insulin or insulin infusion pump therapy. Any change of insulin should be made ... with any other insulin or liquid. If the pump or infusion set does not work right, you may ...

AstraZeneca Submits sNDA for NEXIUM(R) I.V. for Peptic Ulcer Bleed Indication

... bleeding (PUB).(1) To date, there is no proton pump inhibitor (PPI) therapy globally approved for ... in INR and prothrombin time. Like other proton pump inhibitors, esomeprazole may interfere with the ... The cost-effectiveness of high-dose oral proton pump inhibition after endoscopy in the acute ...

Terumo Heart Summarizes Results of DuraHeart(TM) LVAS Implants

... regimen. There was no pump mechanical failure, pump thrombosis, or hemolysis throughout the support ... implantable LVAS combining a centrifugal pump with magnetic levitation of the impeller, ...

Presentation of HeartWare Clinical Results

... noted that one of the key features of the pump is its small size, which allows it to be ... said the early clinical success of the HeartWare pump is a key outcome for the Company as it ... market. The HeartWare(R) LVAD is a full-output pump designed to be implanted in the chest, avoiding ...

Elite Team of Cyclists with Type 1 Diabetes Powers Forward in 2008 Sponsored by Rapid-Acting Insulin Apidra(R)

... diabetes use Apidra(R) in an insulin infusion pump to help control their high blood sugar. "I ... a longer-acting insulin or insulin infusion pump therapy. Any change of insulin should be made ... with any other insulin or liquid. If the pump or infusion set does not work right, you may ...

Research: Popular Diabetes Medications Associated with Increase in Bone Fractures

... not taking the drugs. Diabetes Patients on Clopidogrel and Proton pump Inhibitors at Greater Risk for Cardiovascular Events New research from ... who take clopidogrel (the active ingredient in Plavix(R)) and proton pump inhibitors (PPIs) together. A growing body of evidence highlights the ...

Juvenile Diabetes Research Foundation to Honor Duane DeSisto of Insulet Corporation and Senator Edward M. Kennedy at 27th Annual Hearts & Heroes Gala

... Through the OmniPod System, Insulet seeks to expand the use of insulin pump therapy among people with insulin-dependent diabetes. Founded in 2000, ... blood sugar and give themselves insulin injections multiple times or use a pump - each day, every day of their lives. And even with that intensive care, ...

New Studies Show Popular Heartburn Medications Moderate the Effect of Taking Widely Prescribed Heart Drug

... - Four of the most commonly used proton pump inhibitors raise risk of heart attack and stroke for patients taking ... The study found that using any one of several different proton pump inhibitors (PPIs) in conjunction with clopidogrel increases the risk of ...

HeartWare International Clinical Trial Shows 90% Survival at 180 Days

... events were relatively low despite the unusually long average duration of pump support across the patient group. "These results appear again to ... Ventricular Assist System features the HVAD(TM) pump, the only full-output pump designed to be implanted next to the heart, avoiding the abdominal surgery ...

American Lung Association Study to be Published in the 'New England Journal of Medicine' Finds Prescription Heartburn Medication Does Not Control Asthma Symptoms as Previously Thought

... mild or no symptoms. It is not known whether treatment of GER with proton pump inhibitors (PPIs) in poorly-controlled asthmatics without GER symptoms can ... GER in patients with poorly controlled asthma, treatment with proton pump inhibitors does not improve control. Silent GER is not a likely cause of ...

New Implant Device Remotely Monitors Heart Failure Patients at Northwestern Memorial's Bluhm Cardiovascular Institute

... clinical study. As O'Connell explains, when your heart doesn't pump normally, adequate blood (oxygen and nutrients) may not reach your body ... The back pressure in the lungs due to the inability of the heart to pump the blood effectively can be measured and transmitted by this device. ...

First DuraHeart(TM) Left Ventricular Assist System Implanted in the U.S. Pivotal Trial

... third generation left ventricular assist system combining a centrifugal pump with a magnetically levitated impeller to enter clinical trials in the ... reliability. DuraHeart is the most advanced third generation centrifugal pump by virtue of the magnetically levitated impeller, positioning us for a ...

First U.S. Patient to Receive New Heart-Assist Device Doing Well After Surgery at University of Michigan

... it was implanted in his chest, and connected to his failing heart, to help pump his blood and keep him alive. Shannon, a 62-year-old from Livonia, ... constantly as it is magnetically attracted to the turning motor within the pump housing. This pushes blood into a flexible artificial blood vessel, which ...

Terumo Heart Obtains IRB Approval from the University of Michigan to Initiate DuraHeart(TM) Left Ventricular Assist System U.S. Pivotal Trial

... approval, DuraHeart LVAS will be the first third-generation centrifugal pump with magnetic levitation under investigation in the U.S. We look forward ... is currently the only CE marked implantable LVAS combining a centrifugal pump with magnetic levitation of the impeller, providing exceptional ...

New Subset Analysis of AndroGel(R) Data Highlights Efficacy - Regardless of BMI

... was shown to be safe for men to use over the long term. The AndroGel pump is designed to deliver 1.25 grams of testosterone gel per pump depression, and it is also available in 2.5 and 5 gram packets. This gives ...

FDA Concludes There is No Increased Risk of Cardiac Events for Patients Treated with omeprazole and NEXIUM(R) (esomeprazole magnesium)

... was first launched outside the US in 2000 and in the US in 2001. Proton pump Inhibitors (PPIs) have been shown to be beneficial for patients with ... in the U.S. in 1989, was the first in a class of medications called proton pump inhibitors (PPIs) that block acid production by inhibiting an enzyme ...

September is National Pain Awareness Month

... chronic pain, PRIALT is administered through a programmable microinfusion pump that can be implanted or used externally. The pump then releases the drug on a timely basis into the fluid surrounding the ...

WorldHeart Announces Further Milestone in Miniaturized Assist Pump Development

... hydrodynamic bearings, full magnetic levitation eliminates wear within the pump as well as eliminates dependence on blood properties for rotor suspension. ... The PediaFlow VAD is an implantable, magnetically levitated rotary blood pump based on WorldHeart's proprietary MagLev technology. Configured for ...

AcelRx Announces Positive Phase 2 Results from a Study of ARX-01 Sufentanil NanoTabs in Treating Post-Operative Pain

... similar number in the E.U. Despite its widespread use, the IV PCA architecture has several limitations. The IV line tethering the patient to the PCA pump discourages mobility, which is a critical factor in preventing post-operative complications and advancing recovery. Furthermore, the invasive nature ...

AcelRx Initiates a Phase 2 Study to Evaluate Functionality of Its ARX-01 Sufentanil NanoTab PCA System

... similar number in the E.U. Despite its widespread use, the IV PCA architecture has several limitations. The IV line tethering the patient to the PCA pump discourages mobility, which is a critical factor in preventing post-operative complications and advancing recovery. Furthermore, the invasive nature ...

AstraZeneca Submits NDA for Low Dose Aspirin/Esomeprazole Combination Product

... As with all PPIs, patients treated concomitantly with warfarin may need to be monitored for increases in INR and prothrombin time. Like other proton pump inhibitors, esomeprazole may interfere with the absorption of drugs where gastric pH is an important determinant of bioavailability (e.g., ...

Intarcia Therapeutics, Inc. Announces Completion of Enrollment of ITCA 650 Phase 1b Study for the Treatment of Type 2 Diabetes

... worldwide license to the DUROS delivery technology. The DUROS delivery technology consists of the DUROS device, a matchstick-size miniature osmotic pump that is inserted subcutaneously to provide continuous and consistent drug therapy, and proprietary formulation technology that maintains stability of ...

Torax Medical Launches Pivotal Clinical Study of New Acid Reflux Treatment

... Approximately 19 million adults in the U.S. suffer on a daily basis from the symptoms of GERD. Medical therapy, such as the daily use of proton pump inhibitors (PPIs), may improve heartburn symptoms but it does not address the mechanically defective sphincter, allowing gastric reflux to continue. ...

Meritage Pharma Initiates Phase 2b Clinical Trial of Oral Viscous Budesonide for Pediatric Patients With Eosinophilic Esophagitis

... vomiting, stomach pain, chest pain, heartburn, loss of weight, and food impaction. Other symptoms may include reflux that does not respond to proton pump inhibitor therapy, failure to thrive, poor appetite, malnutrition and difficulty sleeping. The double-blind, randomized, placebo-controlled ...

Thoratec Says Interim Data Analysis Demonstrates Statistical Superiority for the HeartMate II(R) in Destination Therapy Trial

... circulatory support device intended for a broad range of advanced-stage heart failure patients. A continuous flow device, the HeartMate II can pump up to 10 liters of blood per minute and is designed to provide long-term cardiac support. The device is implanted alongside a patient's native heart ...

American Heart Association Journal Report: Miniaturized Heart Pumps May Be Effective for Children Awaiting Transplant

... bleeding and blood clots blocking a blood vessel occurred infrequently, but there was a high incidence of blood clotting in the pumps. Small heart pump devices have been available in Europe for many years, but they are not approved for use in North America. However, the miniaturized Berlin Heart ...

Bioheart Announces 35 Leading U.S. Heart Failure Centers Engaged in Phase II/III Marvel Trial of Myogenic Cells for Treating Advanced Heart Failure

... therapeutic options. ABOUT CONGESTIVE HEART FAILURE Congestive heart failure (CHF), or heart failure, is a condition in which the heart cannot pump enough oxygenated blood to the body's vital organs. People with heart failure find that they cannot exert themselves as they become tired and short ...

Can Implantable Devices for Heart Failure Help Assess Risk of Future Adverse Events for Heart Failure Patients?

... condition in which the heart muscle becomes weakened after it is injured from heart attack or high blood pressure and gradually loses its ability to pump enough blood to supply the body's needs. Many people are not aware they have heart failure because the symptoms are often mistaken for signs of ...

Discharge of First U.S. DuraHeart(TM) Patient

... failure. Significant advances have been made in the DuraHeart LVAS to potentially overcome these problems. Dr. Nojiri explained: "We have a unique pump design that combines advanced "Mag-Lev" technology and a centrifugal pump. The "Mag-Lev" allows for the complete elimination of mechanical contact ...

August 2008 Mayo Clinic Women's HealthSource Highlights Avoiding Blood Pressure Increase at Menopause, Healthful Benefits of Dark Chocolate and Scheduling a Colorectal Exam

... as 5 percent to 10 percent of body weight can lower blood pressure by several points. With less body mass to nourish, the heart doesn't have to pump as hard and the pressure on the arteries decreases. Small, Sweet and Healthful: A Square of Dark Chocolate a Day Offers Benefits ROCHESTER, Minn. ...

Bioheart Reports Promising Results From SDF-1 Modified MyoCell(R) Therapy in Heart Failure Study

... trial involving SDF-1." ABOUT CONGESTIVE HEART FAILURE Congestive heart failure (CHF), or heart failure, is a condition in which the heart cannot pump enough oxygenated blood to the body's vital organs. People with heart failure find that they cannot exert themselves as they become tired and short ...

Duska Therapeutics Licenses Portfolio of Heart Failure Drugs From Duke and Johns Hopkins

... an estimated five million Americans that suffer from congestive heart failure, a condition characterized by the inability of the heart to efficiently pump blood and by fluid accumulation in the lungs and other tissues. An estimated 300,000 deaths each year result from heart failure. "The licensing of ...

Treprostinil Data Presented at American Thoracic Society Conference Demonstrates Significant Clinical Progress in All Four Routes of Administration

... switched from epoprostenol (Flolan(R)) to intravenous Remodulin. Rapid switch from Flolan to Remodulin occurred by directly switching the infusion pump reservoir. Dr. Minai reported that no patients experienced clinical deterioration or change in functional class, and he also observed a favorable ...

TAP Pharmaceutical Products Inc. Announces Phase 3 TAK-390MR Data Demonstrating Higher Overall Healing Versus Lansoprazole in Patients with Erosive Esophagitis

... Products Inc. today reported results from three pivotal Phase 3 studies evaluating investigational new drug TAK-390MR, the first proton pump inhibitor (PPI) with an innovative dual delayed release technology, in healing patients with erosive esophagitis (EE) and in maintenance of healed ....

Thoratec Announces FDA Approval of HeartMate II(R) for Bridge-To-Transplantation

... mechanical circulatory support device intended for a broad range of advanced-stage heart failure patients. An axial flow device, the HeartMate II can pump up to 10 liters of blood per minute, the full output of a healthy heart, and is designed to provide long-term cardiac support. The device is ...
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