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Video: The Journal, Human Genetics, Publishes Results Supporting Interleukin Genetics' Heart Health Test

... the results of clinical studies that support the company's Heart Health Genetic Test to assess cardiovascular risk. The article, titled, "IL1B Gene promoter Haplotype Pairs Predict Clinical Levels of Interleukin-1beta and C-reactive Protein," was published in the journal Human Genetics (123:387-398; May ...

Celldex Therapeutics Receives Fast-Track Designation for CDX-110, a Novel EGFRvIII Vaccine for Glioblastoma

... of primary brain cancer and carries a very poor prognosis with current therapy. CDX-110 is an immunotherapy that targets the tumor-specific growth promoter EGFRvIII that can be expressed by GBM. In the ACTIVATE Phase 2a study, GBM patients treated with CDX-110 showed a median survival time of 30 ...

Celldex Therapeutics Announces Orphan Drug Designation for CDX-110, a Novel EGFRvIII Vaccine for Glioblastoma Multiforme

... Multiforme (GBM). GBM is the most common and aggressive form of brain cancer. CDX-110 is an immunotherapy that targets the tumor-specific growth promoter EGFRvIII. Celldex Therapeutics announced a definitive merger agreement with AVANT Immunotherapeutics, Inc. (Nasdaq: AVAN ) in October 2007. In the ...

Lpath Demonstrates Preclinical Efficacy of Lpathomab(TM) and Initiates Humanization Process

... England, to humanize Lpathomab to create a lead antibody for pre- clinical development. LPA is a bioactive lipid long recognized as a significant promoter of cancer-cell growth and metastasis in a broad range of tumor types, as well as a significant contributor to neuropathic pain. "Humanizing our ...

Gene Therapy Eradicates Pancreatic Cancer in Preclinical Trial Targeting System's Success in Mouse Model Reported in Cancer Cell

... mutant gene delivered via a less-targeted viral promoter driven expression system ... C-VISA-BikDD. They used a gene-based targeting promoter called CCKAR known to be active in pancreatic ... after delivery. A system using a viral promoter such as CMV has the opposite problem: strong ...

Merck at ASCO 2007: Encouraging Results in Progression-Free Survival in Patients With Aggressive Brain Tumors (glioblastoma) Using Cilengitide in Phase I/IIa Study

... of 8.1 months. In a defined patient subgroup with the methylated MGMT gene promoter in the tumor tissue, 91% of patients had six months PFS and the median has ... 54% 6 months PFS, median PFS of 6.9 months;(1) methylated MGMT gene promoter subgroup: 69% PFS and 10.3 months median PFS].(2) Lead investigator ...

Data Show SuperGen's Multi-Targeted Tyrosine Kinase Inhibitor Suppresses Critical Double-Stranded DNA Repair Protein, Rad51

... inhibitors of DNA methyltransferase (DNMT). DNMT1 is considered to be the DNA methyltransferase enzyme mainly responsible for maintaining abnormal promoter methylation in various cancer types. Zebrafish embryos are a viable model for cancer drug research because of their close similarity to humans and ...

Telomerase Presentations at the AACR 2007 Annual Meeting

... of telomere loss prior to telomerase activation in various tumor types, the role of telomere dysfunction in tumorigenesis, and use of the telomerase promoter to drive tumor cell death. "The data presented at AACR contribute to the growing body of evidence regarding the importance of telomerase targeted ...

Lpath Demonstrates 'First-in-Class' AMD Results With Its Lead Drug Candidate, Sphingomab

... Lpathomab(TM), is a monoclonal antibody against lysophosphatidic acid (LPA), a key bioactive lipid that has been long recognized as a significant promoter of cancer-cell growth and metastasis in a broad range of tumor types. Lpath's unique ability to generate antibodies against bioactive lipids is ...
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(Date:7/10/2014)... major cities in New Mexico, nearly every public golf ... than precious potable water supplies. Across the U.S. Southwest ... courses receive treated effluent. Reusing the effluent increases the ... and homeowners alike fertilize their lawns during the growing ... New Mexico State University turfgrass expert has a new ...
(Date:7/10/2014)... 27, 2014  Pomerantz LLP has filed a ... or the "Company")(NYSE-MKT: PVCT) and certain of its ... District Court, Middle District of Tennessee ... a class consisting of all persons or entities ... December 17, 2013 and May 22, 2014, both ...
(Date:7/10/2014)... , July 1, 2014 Smart technology ... for convenience and improved security: NXT-ID, Inc. (OTCBB: NXTD), eBay ... GOOG ), Apple Inc. (NASDAQ: AAPL ), ... (NYSE: MA) NXT-ID, Inc., (OTCQB: NXTD) a biometric authentication ... announce that the second series of 30 second spots on ...
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(Date:7/11/2014)... New York (PRWEB) July 11, 2014 ... ) , filed against Johnson & Johnson’s Ethicon ... Bernstein Liebhard LLP notes that the Texas Attorney ... the company’s marketing of surgical mesh products used ... incontinence. According to a report from kens5.com, the ...
(Date:7/11/2014)... PA (PRWEB) July 11, 2014 Butler Mobility ... of Inclined Platform Lifts . Previously the two ... offering five new beautiful earth tone colors as standard colors ... blend well in the home but will enhance the beauty ... choice for any home color scheme or individual décor. , ...
(Date:7/11/2014)... the number of deer in an area can lower ... infections among people, new research indicates. "Our study ... human interactions with deer, infected nymphal ticks and human ... White-tailed deer are the primary host for adult blacklegged ... study included nearly all the permanent residents of a ...
(Date:7/11/2014)... 2014 (HealthDay News) -- People with the lowest incomes may ... artery disease (PAD), a new study suggests. People with ... the limbs, most often the legs. The condition causes leg ... arteries throughout the body. People with PAD have a higher ... from nearly 6,800 people with PAD who took part in ...
(Date:7/11/2014)... Dennis Thompson HealthDay Reporter ... girl born with HIV who was thought to be cured ... tests showing detectable levels of the AIDS-causing virus in her ... now nearly 4 years old, had remained virus-free even though ... old. Doctors had hoped her remission would open the door ...
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