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Predictive in Medical Technology

CareFirst BCBS Covers eNO Measurement for Diagnosis, Asthma Treatment

... of eNO monitoring have reported that eNO is predictive of asthma in patients with normal lung function, predictive of lack of compliance with medication regimens, and predictive of response to inhaled corticoid steroids," said ...

Swine Flu (H1N1) Infectivity to Increase Markedly and Lethality to Remain Low According to Latest Replikin* Peptide Genomic Data

... bird flu, malaria, and HIV. The company's predictive products and vaccines in development are based ... governments and the private sector in providing predictive tools and vaccines in furtherance of the public ... epidemics. * The company's vaccines and predictive tools are based on the company's discovery of a ...

Vical Completes Enrollment and Reports Positive Interim Data in CMV Vaccine Phase 2 Trial

... as others have noted that T-cell responses may be predictive of better control of CMV reactivation and ... responses following stem cell transplants are predictive of favorable clinical outcome, including limited ... of immunogenicity in the Phase 2 trial will be predictive of clinical benefit, and if so, whether such ...

Champions Biotechnology Begins Preclinical Development of Its Lead Oncology Drug Candidate

... development of advanced preclinical platforms and predictive tumor specific data to enhance and accelerate the ... biology and their response to drugs is more predictive of clinical outcomes in cancer patients. ... as appropriate. The Company also offers its predictive preclinical platform and tumor specific data ...

New Data on MAGE-A3 Cancer Immunotherapy Support Potential Novel Options of Treating Non-Small Cell Lung Cancer and Melanoma

... NSCLC. In a retrospective analysis, a predictive gene signature similar to that observed in ... a potential novel cancer therapy. Validation of a predictive gene signature, combined with selection ... MAGE-A3 treated group. Another signature that is predictive to clinical activity of the MAGE-3 ASCI ...

Champions Biotechnology and Concordia Pharmaceuticals Complete Service Agreement and Begin Preclinical Evaluation of Oncology Drugs

... development of advanced preclinical platforms and predictive tumor specific data to enhance and accelerate the ... biology and their response to drugs is more predictive of clinical outcomes in cancer patients. ... as appropriate. The Company also offers its predictive preclinical platform and tumor specific data ...

Pharmacyclics announces Global Strategic Alliance with Les Laboratoires Servier

... the tumor to chemotherapy and radiation. PCYC has patented the predictive use of the biomarker RAD51 which was found by Pharmacyclics' scientists to potentially underlie resistance to therapy and may be used as a predictive measure of HDAC inhibitor activity that could be useful in the clinic. ...

Hana Biosciences Announces New Positive Interim Efficacy Results in Pivotal rALLy Clinical Trial of Marqibo in Acute Lymphoblastic Leukemia

... of Marqibo, that the safety profile of Marqibo observed to date will be predictive of future results, that the results of the rALLy trial to date will be predictive of future results, that the rALLy trial will meet its study objectives, ...

Hana Biosciences Announces Successful Planned Independent Safety Analysis Supports Ability to Complete Pivotal rALLy Clinical Trial of Marqibo, Its Lead Novel Anti-Cancer Compound

... of Marqibo, that the safety profile of Marqibo observed to date will be predictive of future results, that the results of the rALLy trial to date will be predictive of future results, that the rALLy trial will meet its study objectives, ...

Vermillion Presents Critical Data From Its OVA1 Clinical Trial

... 100% of stage 2-4 cancers while maintaining a greater than 90% negative predictive value among both premenopausal and postmenopausal patients. "We are ... from this disease. A diagnostic test is needed that can provide adequate predictive value to stratify patients with a pelvic mass into high risk of invasive ...

Breast Cancer Clinical Results Show Test Can Differentiate Normal, Early and Later Stage Cancers

... TORONTO, Feb. 5 /PRNewswire-FirstCall/ - predictive medicine company PreMD Inc. (TSX: PMD; PREMF.pk) today announced that its ... disease," he added. About PreMD Inc. PreMD Inc. is a leader in predictive medicine, dedicated to developing rapid, non-invasive tests for the early ...

Agendia's MammaPrint(R) Predicts Response to Neoadjuvant Chemotherapy in Breast Cancer

... Findings in the neoadjuvant setting support MammaPrint's predictive power for chemotherapy response, in addition to its previously ... II or III breast cancer were analyzed to assess MammaPrint's potential predictive power. 20 percent of the 144 patients in the poor prognosis signature ...

Alexion Reports Positive Results from AEGIS Registration Study of Soliris in Japanese Patients With PNH

... relationships, the possibility that results of clinical trials are not predictive of safety and efficacy results of Soliris in broader patient populations, the possibility that initial results of commercialization are not predictive of future rates of adoption of Soliris, the risk that third parties won't ...

First Clinical Experience With Soliris(R) in Treating Patients With Two Rare Complement-Mediated Diseases Presented at ASH Annual Meeting

... relationships, the possibility that results of clinical trials are not predictive of safety and efficacy results of Soliris in broader patient populations, the possibility that initial results of commercialization are not predictive of future rates of adoption of Soliris, the risk that third parties won't ...

Novel Therapeutic Approaches May Transform Treatment and Improve Patient Outcomes in Several Platelet Disorders

... dexamethasone alone, the identification of clinical and laboratory factors predictive of response, and the pharmacokinetic parameters of rituximab (the level of ... and 59 percent, respectively. No clinical or laboratory factors predictive of a sustained response were identified in the study. There was a mild ...

PreMD Inc. Enters Clinical Study with Cosmetics Conglomerate

... TORONTO, Nov. 24 /PRNewswire-FirstCall/ - predictive medicine company PreMD Inc. (TSX: PMD; PREMF.pk) today announced that it ... near future." About PreMD Inc. PreMD Inc. is a leader in predictive medicine, dedicated to developing rapid, non-invasive tests for the early ...

GEN Reports on the Trend Toward Predictive Toxicogenomics

... out a new compound's mechanism of action and eventually developing a predictive toxicology technique, according to the November 15 issue of GEN . ( ... of biomarkers for kidney toxicity. Groups such as The C-Path predictive Safety Testing Consortium are examining published toxicogenomics multiple ...

Hologic Releases the Results of the Cervista(TM) HPV Clinical Trials

... were as follows: -- 100% CIN3 detection and a corresponding negative predictive value of 100%. Patients with CIN3 are at the highest risk of developing ... sensitivity of the test for CIN2+ was 92.8%, with a corresponding negative predictive value of 99.1%. Patients with CIN2 are at risk of developing cervical ...

Soliris(R) Improved Fatigue Independent of Changes in Anemia in Patients with PNH by Controlling Hemolysis

... improvement (odds ratio 1.11, P respectively), hemolysis reduction was predictive of an improvement in fatigue independent of an improvement in anemia in ... the possibility that initial results of commercialization are not predictive of future rates of adoption of Soliris, the risk that third parties won't ...

Genomic Health Announces Results of Initial Studies to Develop Predictive Tests for Targeted Therapies

... the Eastern Cooperative Oncology Group (ECOG). Researchers evaluated the predictive utility of progesterone receptor (PR) protein expression by IHC in a ... author of the study. "Further research to narrow down which genes are most predictive and validate their use could potentially yield a new panel of genes that ...

Ipsogen Announces Three Studies at the American Society of Clinical Oncology (ASCO) Meeting Extending the Utility of the Genomic Grade Index for Predicting Response to Chemotherapy in Breast Cancer

... from MDACC and Institut Bordet (Brussels, Belgium) validated the GGi as a predictive marker of chemotherapy response in 229 patients with HER2-normal breast ... tumor in a pathology laboratory. This study concludes that high GGi is predictive for increased sensitivity to T/FAC chemotherapy in both ER- and ER+ ...

Data Presented at the American Psychiatric Association (APA) Annual Meeting Demonstrate Iloperidone's Efficacy and Safety, With Low Rates of Movement and Metabolic Adverse Events

... with efficacy of iloperidone. -- The highest specificity and positive predictive value were observed with rs11851892 (NPAS3) with a change from ... score of -20.12 (p=0.000093) -- The highest sensitivity and negative predictive value were seen with rs9643483 (XKR4) with a change from baseline to ...

Alexion Completes Enrollment in AEGIS Registration Study of Soliris(R) (eculizumab) in Patients with PNH in Japan

... relationships, the possibility that results of clinical trials are not predictive of safety and efficacy results of Soliris in broader patient populations ... study), the possibility that initial results of commercialization are not predictive of future rates of adoption of Soliris, the risk that third parties ...

Multiple Dose Clinical Trial of TorreyPines Therapeutics' Tezampanel Demonstrates Compound is Safe and Well-Tolerated

... including whether the results of the Phase IIb trial are predictive of results in subsequent trials of tezampanel, whether the results of the Phase I trial are predictive of results in subsequent trials of tezampanel or NGX426, whether further ...

Pharmacokinetic Data Suggest NGX426, TorreyPines Therapeutics' Oral Prodrug of Tezampanel, May be Effective in Treating Acute Migraine Headache

... including whether the results of the Phase IIb trial are predictive of results in subsequent trials of tezampanel, whether the results of the Phase I trial are predictive of results in subsequent trials of NGX426, whether the areas under the ...

Studies Suggest Key Correlation Between Lung Cancer Subtype and Treatment Outcomes

... Lilly Studies predictive Factors to Better Target Patients for ALIMTA(R) (pemetrexed for ... with ALIMTA in the second-line setting. The data suggested that favorable predictive factors for ALIMTA treatment in the second-line NSCLC setting could ...

Anadys Pharmaceuticals Presents Preclinical Results on ANA598, a Non-Nucleoside Inhibitor of the NS5B Polymerase, at the 14th International Symposium on Hepatitis C Virus and Related Viruses

... the use of doses in preclinical studies that are designed to be predictive of human doses, the belief that achieving blood levels that are many-fold ... statements. For example, the results of preclinical studies may not be predictive of future results, and Anadys cannot provide any assurances that any of ...

HistoRx and Radiation Therapy Oncology Group Initiate Brain Tumor Biomarker Research Partnership

... reagents developed in the course of the collaboration for clinical use as predictive diagnostics. The RTOG studies will use a combination of high-throughput ... tool that is enabling pathologists and clinicians to integrate data from predictive biomarker studies confidently into research, diagnosis, and patient ...

DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947

... trial in patients with major depressive disorder. In animal models highly predictive of antidepressant action, DOV 21,947 was more potent than Tofranil(R), a ... of depression. In addition, at doses similar to those active in models predictive of antidepressant action, DOV 21,947 produced a significant weight loss in ...

Vectibix(R) in Combination With Chemotherapy Significantly Improved Progression-Free Survival in First-Line Metastatic Colorectal Cancer

... of Research and Development at Amgen. "These are the first prospective Phase 3 data to demonstrate the utility of KRAS mutational analysis as a predictive biomarker." Overall, the adverse event profile was as anticipated for an anti-EGFR antibody in combination with oxaliplatin-based ...

Unlikely Treatment Identified by BrainCells Neurogenesis Platform Improved Clinical Outcomes in Patients Suffering From Depression

... diseases. Neurogenesis is the process by which endogenous stem cells in the adult human brain produce new brain tissue, including neurons. With its predictive screening platform, BCI can direct the selection and development of neurogenic compounds, increasing the opportunity for successful clinical trials ...

Exenatide Once Weekly Provided Superior Glucose Control Compared to Lantus(R) in Head-to-Head DURATION-3 Study

... not confirming previous results, or not achieving the intended clinical endpoints; the DURATION-3 superiority study results potentially not being predictive of real world use including results relative to other diabetes medications; pre-clinical trials not predicting future results; label expansion ...

Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) for the Treatment of Fabry Disease

... and, our dependence on third parties in the conduct of our clinical studies. Further, the results of earlier clinical trials and studies may not be predictive of future results. Additionally, all forward looking statements are subject to other risks detailed in our Annual Report on Form 10-K for the year ...

CRi Oosight(TM) Instrument Crucial in IVF Breakthrough Demonstrating a Correlation Between Non-Invasive Egg Metrics and Pregnancy

... researchers from the School of Women's & Children's Health at the University of New South Wales . The group determined that while absolute predictive criteria for the selection of the best embryo for single-embryo transfer remain elusive, CRi's Oosight instrument provides a useful, non-invasive ...

Meta-Analysis of Clinical Data Showed No Increased Risk of Cardiovascular Events Associated With Exenatide Use: Data Presented at ADA 2009

... not being submitted in a timely manner or receiving regulatory approval; the clinical data analyses mentioned in this press release not being predictive of real-world experience; or manufacturing and supply issues. The potential for BYETTA may also be affected by government and commercial ...

Arena Pharmaceuticals Announces Lorcaserin Data Demonstrating Highly Significant Categorical and Absolute Weight Loss and Improvements in Secondary Endpoints Associated with Cardiovascular Risk

... cost of Arena's lorcaserin program and other of its research and development programs; results of clinical trials or preclinical studies may not be predictive of future results; clinical trials and studies may not proceed at the time or in the manner Arena expects or at all; Arena's ability to partner ...

Arena Pharmaceuticals Announces the Presentation of Lorcaserin Phase 3 BLOOM Data at the American Diabetes Association's 69th Scientific Sessions

... cost of Arena's lorcaserin program and other of its research and development programs; results of clinical trials or preclinical studies may not be predictive of future results; clinical trials and studies may not proceed at the time or in the manner Arena expects or at all; Arena's ability to partner ...

Scientific Data Relating to Cinryze(TM) Presented at 6th Annual C1 Inhibitor Deficiency Workshop

... from the open label study will demonstrate that Cinryze successfully treats all types of acute hereditary angioedema (HAE) attacks and may not be predictive of the results of any future testing. The FDA may view the data regarding the use of Cinryze for acute treatment of HAE we have submitted as a ...

Novavax Completes Enrollment of Its Second Phase II Seasonal Influenza VLP Vaccine Clinical Trial

... or historical experience include risks relating to the early stage of Novavax's product candidates under development; current results may not be predictive of future pandemic results, results of our seasonal influenza vaccine or any other vaccine that we may develop; further testing is required before ...

Jubilant Enters Research Collaboration With AstraZeneca

... of future events on current and developing circumstances. Such statements are subject to numerous risks and uncertainties and are not necessarily predictive of future results. Actual results may differ materially from those anticipated in the forward-looking statements. Jubilant Organosys may, from time ...
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(Date:4/20/2014)... the body,s master cells demonstrate a bizarre property ... a study published today from scientists at the University ... is one which may have application as wide-ranging as ... stretched will contract. For example, if one pulls on ... The opposite is also true: squeeze a material and ...
(Date:4/20/2014)... to treat lung, breast and pancreatic cancers also promote ... University of California, San Diego School of Medicine have ... surface of drug-resistant tumors that appears responsible for inducing ... cancer cells. , The findings, published in the ... Biology , may point to new therapeutic opportunities for ...
(Date:4/20/2014)... Although doctors have long known that people with Down ... leukemia (ALL) during childhood, they haven,t been able to ... Institute investigators has uncovered a connection between the two ... the journal Nature Genetics , the researchers track ... abnormality in Down syndrome to the cellular havoc that ...
Breaking Biology News(10 mins):Bulletproof nuclei? Stem cells exhibit unusual absorption property 2Cancer stem cells linked to drug resistance 2Dana-Farber researchers uncover link between Down syndrome and leukemia 2Dana-Farber researchers uncover link between Down syndrome and leukemia 3
(Date:4/18/2014)... a brain-related discovery that could revolutionize doctors, perception ... opens up the possibility that environmental and/or genetic ... activity that the researchers have identified as helping ... Neuroscience has just published a paper about ... of psychology and his doctoral student John Gaspar, ...
(Date:4/18/2014)... discovery by Northwestern Medicine scientists could lead to potential ... in people with scleroderma. , Fibrosis, or scarring, ... of the skin and lungs can lead to serious ... concept for new therapeutic options centers on findings made ... who identified the role that a specific protein plays ...
(Date:4/17/2014)... specifically associated with the risk of a difficult-to-diagnose ... of all breast cancer cases. , The largest ... invasive lobular carcinoma, gives researchers important clues to ... breast cancer, which can be missed through screening. ... journal PloS Genetics , was co-led by ...
(Date:4/17/2014)... PLOS Pathogens , children who live in regions of ... immune response to infection with malaria parasites that may ... and illness and partially control the growth of malaria ... develop future interventions that prevent or mitigate the disease ... 200 million cases of malaria occur worldwide, resulting in ...
(Date:4/17/2014)... 2014) Two recent papers by a University ... may help scientists develop treatments or vaccines for ... encephalitis and other disease-causing flaviviruses. , Jeffrey S. ... genetics at the School of Medicine and an ... Institute, and colleagues recently published articles in the ...
Breaking Medicine News(10 mins):Health News:Scientists discover brain's anti-distraction system 2Health News:New clues on tissue scarring in scleroderma 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 3Health News:Study sheds light on how the immune system protects children from malaria 2Health News:CU researchers discover target for treating dengue fever 2
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