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Population in Medical Technology

Neurointerventionists Expand Research to Quality of Life in Aneurysm Patients Following Minimally Invasive Coiling Treatment

... Coiled Patients Compare More Closely to Normal population Than They Do to Patients Who Previously Underwent ... group scores were analyzed against a reference population consisting of fully healthy individuals. In this ... had been successfully coiled and the reference population were not significantly different. However, ...

Cephalon Provides Clinical Update on Lestaurtinib in Relapsed Acute Myelogenous Leukemia

... show the benefit of lestaurtinib in this patient population when given in sequence with standard induction ... did not demonstrate a benefit for this patient population but we remain committed to oncology clinical ... for this molecularly targeted patient population with a poor prognosis and few treatment options," ...

Pixantrone Produces High Rates of Complete and Partial Remissions Even Among Aggressive NHL Patients With Extensive Prior Doxorubicin Treatment or Prior Rituximab Treatment

... noted that overall response rates of 30% in this population of patients would represent a significant advance ... for pixantrone in this difficult to treat patient population for whom few options exist." About the ... currently used for the treatment of this patient population and selected by the physician. CTI ...

ISTA Pharmaceuticals Highlights Bepreve(TM) Clinical Data at the Association for Research in Vision and Ophthalmology (ARVO) 2009 Annual Meeting

... minimal adverse events in a healthy pediatric population from 10-17 years of age. Results were presented ... Ophthalmic Solution in a Healthy Pediatric population from Ten to Seventeen Years of Age", ISTA ... for six weeks was safe in a healthy pediatric population from 10-17 years of age. The pediatric subjects ...

EAU Position Statement on Screening for Prostate Cancer

... mortality reduction of at least 20% by PSA-based population screening in 162,000 asymptomatic men aged 55-69 ... to be treated in excess of the control group population to save one prostate cancer death. Results of the ... are insufficient to recommend the adoption of population screening for prostate cancer as a public ...

Osprey Pharmaceuticals U.S.A., Inc. Initiates Phase Ib Clinical Trial in IgA Nephropathy

... fusion protein therapeutics, known as Leukocyte population Modulators (LPMs), for the treatment of ... proprietary platform of therapeutic Leukocyte population Modulators (LPMs). LPMs specifically target ... proprietary therapeutic platform of Leukocyte population Modulators (LPMs). Osprey Pharmaceuticals U.S.A. ...

Hana Biosciences Announces New Positive Interim Efficacy Results in Pivotal rALLy Clinical Trial of Marqibo in Acute Lymphoblastic Leukemia

... to nine or more out of the target evaluable population of 56 subjects. Completion of rALLy will satisfy ... treatment available to this very sick ALL patient population for whom there are currently no approved or ... response duration, and survival. The patient population is defined as Philadelphia chromosome-negative ...

Study of Cannabinoid Medicine for Pain Found Patients Got 'High,' but Effects Not Related to Pain Relief

... 10mg, or 20 mg of dronabinol. The second population was not suffering from pain, but they ... hour. After two hours, patients in the first population (synthetic cannabinoid medicine) were found to ... effects that patients from the second population (smoked marijuana) did after 30 minutes. ...

New Analysis Estimates Numbers of Older U.S. Adults Who May Benefit From Statin Therapy

... "That's nearly 80 percent of this segment of the population who could potentially be recommended a statin ... processes about preventive measures for the population as a whole. All of this will need to be ... problem is likely to increase if the size of the population eligible for statins increases, she said. ...

Two-Year Follow-Up Data Demonstrates Preservation of Adequate Mitral Valve Area in Patients Treated with the MitraClip(R) System

... observations were extended to a larger study population with longer term follow up, and included patients ... and those with functional MR. The study population for the present analysis included 107 patients ... were analyzed for the 96 patients in the study population who received the MitraClip(R) device. All ...

Pivotal Phase III Data Confirm the Efficacy and Safety of Arpida's Intravenous Iclaprim in Treating Patients With Complicated Skin and Skin Structure Infections

... 85.3 percent for linezolid in the intent-to-treat population and cure rates were 92.3 percent and ... modified clinical evaluable (MCE). -- The ITT population included all patients who received at least one dose of medication; -- The MITT population included all patients in the ...

Sangamo BioSciences Announces Nature Biotechnology Study Demonstrating the Use of Zinc Finger Nucleases to Generate HIV Resistant T Cells

... treatment with our CCR5-specific ZFNs generates a population of HIV-resistant human T-cells similar to the ... of ZFN- generated CCR5-disrupted cells in the population upon long-term exposure to virus (>50 days). ... so-called "R5" strains. A small fraction of the population carries a mutation in their CCR5 gene, called the ...

Phase III Data Show Vanda Pharmaceuticals' Tasimelteon (VEC-162) Significantly Improves Sleep in Patients with Chronic Insomnia

... that the sleep disruption in this patient population occurred primarily during the first third of ... when the sleep disruption was greatest in this population of chronic primary insomnia patients. -- Mean ... the portion of the night in which the patient population studied suffered the greatest impairment. These ...

Arpida Provides Further Comments on the Pivotal Phase III Trials

... The correction for this imbalance in the PP population results in the Modified Clinically Evaluable ("MCE") population and shows that the MCE population is in close agreement with the ITT population. ...

Three Year Analysis of Treatment Efficacy, Cosmesis, and Toxicity Support use of the Hologic Mammosite Radiation Therapy System

... Study Represents Largest Patient population to Date BEDFORD, Mass., Feb. 25 ... with DCIS. An analysis of the overall registry population with a median follow-up of 30.1 months, showed a ... Surgeons Registry represents the largest patient population treated with the MammoSite Radiation ...

FDA Grants Approval to Extend U.S. Enrollment and Clinical Trial

... ten million people worldwide. As the U.S. population ages, it is likely that the incidence of AF will ... an estimated six percent of the current U.S. population over age 60, and ten percent of the population over age 80, affected by the condition. AF is a ...

Long-Term Soliris(R) Therapy Improved or Stabilized Kidney Function in Patients With PNH

... by reductions in transfusions in a diverse population of patients with PNH. Soliris continued to be ... of progression of this overall untreated population of PNH patients to a major clinical kidney event, ... of life, and anemia in this diverse population of PNH patients," said Leonard Bell, MD, Chief ...

Soliris(R) Demonstrates Reductions in Hemolysis and Improvements in Fatigue, Overall Quality of Life and Anemia in a Broad Population of PNH Patients

... overall quality of life and anemia in a diverse population of patients with a rare blood disorder called ... efficacy of eculizumab in a broader, more diverse population of PNH patients than the TRIUMPH study by ... (8) Wang, et al. Clinical significance of a minor population of paroxysmal nocturnal hemoglobinuria-type cells ...

SEROQUEL XR(TM) Receives Approval From FDA for Maintenance Treatment of Schizophrenia

... over 2 million American adults -- about 1% of the population 18 years and older.(4,5) The FDA approval for ... risk of diabetes in the schizophrenic population and the increasing incidence of diabetes in the ... 2.4 million American adults -- about 1.1 % of the population age 18 and older -- suffer from schizophrenia.(5) ...

Hopkins Report: Focusing on Family Planning Lessens HIV Impact

... born with HIV, according to the latest issue of population Reports, "Family Planning Choices for Women With ... Resources Online: The full-text version of this population Reports issue is available at ... To order this latest population Reports issue and its companion INFO Reports ...

Poniard Pharmaceuticals Announces Updated Results of Picoplatin Phase 2 Trial Demonstrating Survival Benefit in Small Cell Lung Cancer Patients

... survival rate of 17.6 percent in the Phase 2 population of mostly platinum-refractory and -resistant ... of picoplatin in this difficult-to-treat patient population and compare favorably with the median survival for the entire population of relapsed patients who receive other ...

NOVAVAX Achieves Pandemic H1N1 Influenza Production Milestone

... concurrently to produce materials for a clinical study in the elderly population with our Seasonal Flu vaccine." "The accomplishments announced ... a Phase II study with its Seasonal Flu vaccine candidate in the elderly population during Q4, 2009. About Novavax Novavax, Inc. is a ...

FDA Issues Complete Response Letter for INTUNIV(TM) (guanfacine) Extended Release for the Treatment of ADHD in Children and Adolescents

... Replication.(15) When this percentage is extrapolated to the full US population aged 18 and over, approximately 9.8 million adults are believed to have ... Am J Psychiatry. 2006; 163:716-723. 16. Annual Estimates of the population by Selected Age Groups and Sex for the United States: April 1, 2000 to ...

Correction to Earlier Release From Jewish Hospital and University of Louisville

... what another institute nationally has done is that we have injected a pure population of stem cells, the c-kit-positive cells. The other institution injected ... actual therapeutic cell. Our study involves a specific, well-characterized population of undifferentiated cells: the c-kit-positive cardiac stem cells are ...

R788 in TASKi3 Clinical Trial Does Not Meet Efficacy Endpoints in RA Patients Who Had Previously Failed Biologic Therapies - Results Incongruent

... therapies are used. We have shown excellent results in that patient population in our earlier TASKi1 and TASKi2 studies, and we believe that patient population represents the large market opportunity for this product," said James M. ...

Landmark Study for GSK's Cervical Cancer Vaccine Published in The Lancet

... who received at least one vaccine dose. This group comprised a diverse population of women including those with evidence of current or previous HPV ... with high grade smear test results. This was intended to represent general population of sexually active young women TVC-naive included all women who ...

5-Year Study Published in Diabetologia Demonstrated Long-Term Safety of Lantus(R) Compared to NPH

... stereoscopic fundus photographs was used. Main characteristics of the population were the following and well balanced between groups: : mean age 55, 54% ... vs 8.3% (glargine vs NPH) diabetes duration 11 years, and about 70% of the population was already treated with insulin prior to study entry. Similarly ...

New Study Evaluating the ADHD Medication VYVANSE(R) (lisdexamfetamine dimesylate) CII Demonstrated No Change in the Pharmacokinetic Profile of VYVANSE When Coadministered with Prilosec OTC(R) 40 mg (20 mg X 2), a Commonly Used Proton Pump Inhibitor (PPI)

... Survey Replication. When this percentage is extrapolated to the full US population aged 18 and over, approximately 9.8 million adults are believed to have ... Survey Replication. When this percentage is extrapolated to the full US population aged 18 and over, approximately 9.8 million adults are believed to have ...

Autism Genes Discovered; Help Shape Connections Among Brain Cells

... we discovered may contribute to as many as 15 percent of ASD cases in a population -- typically referred to as the population -- attributed risk of the variant." Hakonarson's team first performed ...

Study Data Show Positive European Experience With DuraHeart Left Ventricular Assist Device for Advanced Stage Heart Failure Patients

... and a wholly owned subsidiary of Terumo Corporation. "In a patient population with advanced disease at imminent risk of death due to end-stage left ... therapy." Overall, the mean support duration for this study population was 242 days plus or minus 243 days (range: 19 - 1148, median: 161) with a ...

Impulse Dynamics Announces Pivotal Results at the American College of Cardiology Annual Meeting Late-Breaking Session

... Center. In a subgroup representing the "less sick" half of the study population (NYHA Class III with ejection fraction 25% and above), the study found ... patients. We have a clear pathway for further studies of CCM in this population which we believe will have favorable outcomes in the near future." ...

Mayo Clinic: Retired National Football League Linemen Have High Incidence of Sleep Apnea

... show that retired linemen need to realize that they are a very high risk population and may need evaluation and treatment." Previous research by various ... mortality is reported in linemen, as compared to people in the general population of the same age who are not professional football players. Research is ...

First Swiss Patients Treated with the Percutaneous MitraClip(R) System

... heart failure patient continues to be the fastest growing segment of the population undergoing treatment with the MitraClip(R) system and the initial commercial results in this population are very encouraging." About the MitraClip(R) Procedure ...

Pixantrone Increases Progression-Free Survival by 81% Compared to Standard Chemotherapeutic Agents in Phase III Relapsed Aggressive non-Hodgkin's Lymphoma Trial

... Executive Officer of CTI. "Pixantrone is the first agent in this patient population to demonstrate a significant and meaningful PFS advantage. We believe ... another single-agent drug currently used for the treatment of this patient population and selected by the physician. The trial was designed to examine the ...

STALLERGENES: Oralair(R) Grasses Obtains a Pediatric MA(1) in Germany

... to World Health Organization (WHO) estimates, 20 to 25% of the world's population suffer from respiratory allergic symptoms (rhinitis and/or asthma). By 2020, 50% of the world's population will be affected by allergy according to the ISAAC study. According to ...

Inclinix Releases Next Generation Critical Population Research(R) (CPR) for Clinical Trial Investigator Site Selection and Patient Recruitment

... solutions provider, announces the release of its next generation Critical population Research(R) (CPR) system. A proprietary technology that integrates ... with a global analysis of prospective sites. Critical population Research identifies where patients with a specific condition are ...

Genomas Clinical Study Finds Increased Prevalence of Drug Metabolism Deficiencies in Patients With Serious Psychotropic Side Effects

... gene analysis revealed that 57 percent of individuals in the psychiatric population were carriers of multiple gene variations associated with no or poor drug ... deficiencies based on the gene variants predominantly observed in the population experiencing side effects," said Gualberto Ruano, M.D., Ph.D., President ...

New Keppra XR(TM) Data Highlight Its Role for Patients with Partial-Onset Seizures

... Keppra XR Data Presented at 2008 AES Annual Meeting: -- population Pharmacokinetics of Levetiracetam Extended-Release 500 mg Tablets ... and Armel Stockis UCB Pharma, Braine-L'Alleud, Belgium -- population Dose-Response Modeling of Levetiracetam Extended- and Immediate-Release ...

Dacogen(R) (decitabine for injection) Data Presented on a Phase II Clinical Trial in Elderly Patients with Acute Myeloid Leukemia (AML)

... the expert-reviewed overall response rate in the intent-to-treat (ITT) population was 26 percent, with morphologic CR in 24 percent of patients and CR with ... "These data indicate that further trials are warranted in this elderly population and we look forward to seeing additional Dacogen results reported." ...

Research Highlights New Approaches to Prevent Blood Clots in Several High-Risk Patient Populations Including Largest Study Ever to Examine Use of Blood-Thinning Medication in Patients With Cancer

... was determined first by a test for non-inferiority in the per-protocol population of 1,702 patients, followed by a test for superiority in the intention-to-treat population of 1,924 patients. The results indicated that rivaroxaban ...
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(Date:7/28/2014)... of two additional coral communities showing signs of damage from ... the 2010 spill in the Gulf of Mexico. The discovery ... of biology at Penn State University. A paper describing this ... the Gulf of Mexico will be published during the last ... the journal Proceedings of the National Academy of Sciences ...
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(Date:7/28/2014)... Yale School of Medicine have pinpointed a mechanism in part ... in the blood, linking it to both type 1 and ... 28 issue of Proceedings of the National Academies of ... enzyme located in a part of the hypothalamus known ... in motion that control glucose levels in the blood," said ...
Breaking Biology News(10 mins):Impact of Deepwater Horizon oil spill on coral is deeper and broader than predicted 2Scientists discover genetic switch that can prevent peripheral vascular disease in mice 2Glucose 'control switch' in the brain key to both types of diabetes 2
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