Pain in Medical Technology

NeurogesX Announces Preliminary Results of FDA-Requested Qutenza(TM) Study

... focused on developing and commercializing novel pain management therapies. Its initial focus is on ... Qutenza, a dermal patch designed to manage pain associated with peripheral neuropathic pain conditions. Qutenza is currently approved in the ...

International Journal of Occupational and Environmental Health Features Discovery of Asbestos-Related Pain Origin from Scientists at the Karmanos Cancer Institute in Detroit

... a probable reason for the unrelenting chest pain experienced in certain patients with ... logical explanation of the unrelenting pain which some patients experience," said Dr. Harbut. ... and history of the patient's intractable pleural pain meets the criteria for diagnosis of asbestosis. ...

Music & Medicine: Unique Collaboration Combines Performing Arts and Science

... those with small hands -- from developing pain caused by playing keyboards. "We're ... Yoshimura has studied piano-related pain among pianists in the past. She and Chesky ... One possible answer to alleviating the pain certain players feel while performing is the ...

Elbit Imaging Ltd. Announces - Swiss Team Uses InSightec's ExAblate(R) 4000 Brain System to Treat Patients With Functional Brain Disorders

... adult patients diagnosed with chronic neuropathic pain successfully underwent non-invasive deep brain ... transcranial TcMRgFUS and showed improvement in pain scores and reduction of pain medication with no adverse effects at three ...

Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM)

... LIDODERM(R), a topical patch to relieve the pain of postherpetic neuralgia; PERCOCET(R) and ... for the relief of moderate-to-severe acute pain where the use of an opioid is appropriate; OPANA(R) ER tablets for the relief of moderate-to-severe pain in patients requiring continuous, ...

Iontophoretic Drug Delivery System (IDDS) Containing Lidocaine and Epinephrine is Effective in Reducing Pain Associated With Insertion of an Intravenous Catheter in a Phase 2 Clinical Trial

... intravenous catheter, subjects evaluated their pain using the Visual Analog pain Scale (VAS) scoring system and were asked if they ... 8 minutes of treatment) the mean Visual Analog pain Scale (VAS) results recorded by the subject ...

Mayo Clinic Proceedings: A Comprehensive Review of Addiction to Prescription Painkillers Among Patients and Physicians

... gastrointestinal tract; decrease perception of pain and reaction to pain; and increase pain tolerance. Side effects include sedation, ... of drug delivery; increased public awareness of pain management options and the appropriateness of ...

Relievant Medsystems Announces Completion of $20 Million Financing

... of our technology." Chronic low back pain impacts nearly one-third of the population and ... patients have few choices - escalating use of pain medications, continued suffering or invasive ... Intracept System treats chronic low back pain with a simple, minimally invasive procedure. In ...

AcelRx Announces Positive Phase 2 Results from a Study of ARX-01 Sufentanil NanoTabs in Treating Post-Operative Pain

... for the management of acute post-operative pain in patients requiring opioid analgesia during ... NanoTabs for management of post-operative pain following major abdominal surgery reported statistically significant reductions in pain intensity over the 12-hour study period. ...

King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use

... Drug Dependence. King is also developing other pain medicines employing unique technology platforms ... in a physician's arsenal of safe and effective pain medicines that can help with an overall risk ... for the Treatment of Acute, Moderate to Severe pain Following Bunionectomy Surgery in Adult Patients ...

Jazz Pharmaceuticals and UCB Announce Second Phase III Study of Sodium Oxybate in Patients With Fibromyalgia Meets Primary Endpoints

... III study show highly significant decreases in pain and fatigue and improved daily function in ... study, sodium oxybate significantly decreased pain and fatigue and improved daily function and ... who achieved at least 30 percent reduction in pain from baseline to endpoint based on ...

Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia

... and clinically meaningful improvement in pain and the core symptoms associated with ... of fibromyalgia. Widespread chronic pain is the hallmark of fibromyalgia, but the vast ... patients who achieved at least 30% reduction in pain from baseline to endpoint based on ...

New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients

... or sores on your body diarrhea or stomach pain burning when you urinate or urinate more ... eyes look yellow, poor appetite or vomiting, or pain on the right side of your stomach. Low ... joint or muscle pain, becoming very tired, chest pain or shortness of breath, swelling of the feet, ...

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

... improvement from baseline in both total back pain and morning stiffness measures were switched to ... inflammatory arthropathy manifesting with joint pain and swelling that can lead to joint destruction ... arthritis, and symptoms of inflammatory back pain often first present in people under the age of 35 ...

Merz Pharmaceuticals Announce Three Studies of NT-201 - (Botulinum neurotoxin type A Free From Complexing Proteins)

... were dysphagia (4.3% vs 8.5% vs 16.0%), neck pain (4.3% vs 8.5%, vs 10.0%), and injection site pain (2.2% vs 8.5% vs 2.0%) for each group, ... weakness (3.6% vs 6.5% vs 22.6%), and neck pain (3.6% vs 3.2%, vs 22.6%) for each group, ...

Single Port Surgeries Now Performed at University Medical Center at Princeton

... With virtually no visible scar, less pain and faster recovery time, "single port ... A single incision also means less post-operative pain and slightly reduced risk of infection than a ... observed that patients are managing with less pain medication than patients who have had traditional ...

NeurogesX Receives FDA Orphan Drug Designation for Qutenza(TM) for Treatment of Postherpetic Neuralgia

... focused on developing and commercializing novel pain management therapies, announced today that the ... dermal patch for the management of neuropathic pain in patients with postherpetic neuralgia (PHN). ... focused on developing and commercializing novel pain management therapies. Its initial focus is on ...

Horizon Therapeutics' HZT-501 Significantly Reduces Incidence of NSAID-Induced Upper Gastrointestinal Ulcers in Patients With Mild-to-Moderate Pain

... demonstrated that patients with mild-to-moderate pain treated with HZT-501 developed 50 percent less ... in treating patients with mild to moderate pain who are at risk for upper GI ulcers." ... drugs in the world for the treatment of chronic pain and inflammation with more than 90 million ...

Back to Normal: Surgery Improves Outcomes for Spine Patients

... -- experience substantially greater relief from pain over time compared to those who do not have ... criteria, including: nerve pain in the legs spinal stenosis revealed on ... 80 percent of Americans suffer from back pain at some point in their lives. ...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

... disorders (14% to 38%), and injection-site pain (20% to 50%). Hypoglycemia (4%), hyperglycemia ... abdominal pain, gas, constipation, vomiting, pain on injection, high or low blood sugar levels and ... stomatitis, dehydration, pneumonitis, abdominal pain and asthenia. The most common laboratory ...

Classwide Opioids REMS: A Good Idea, Implement Carefully

... Controlled-release opioids include prescription pain medications that release the medication over a ... Will it be harder for patients in pain to get the medications they need if prescribers ... Will prescribers prescribe the best pain medication for the patient, or instead prescribe ...

New Phase 3 Study of Tapentadol Immediate Release Tablets Published in Current Medical Research and Opinion Journal

... Tapentadol Efficacy and Tolerability for Acute pain Patients RARITAN, N.J., May 26 ... such as nausea and vomiting. The use of opioid pain medicines during and after surgery is a leading ... provided patients with equivalent efficacy in pain relief following orthopedic surgery and ...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

... Leader, Psychiatry, Central Nervous System and pain Therapeutic Area, Johnson & Johnson ... pulse, heart rate, or blood pressure; or muscle pain and weakness. Treatment should be stopped if the ... indigestion, sleepiness, weight gain, pain in the limbs, and dry mouth. In a study of ...

Feldenkrais(R) Movement Institute Announces Simple Non-Surgical Solutions for Jaw and Facial Pain (TMJ)

... on CD. The program offers sufferers of jaw pain an inexpensive and effective self-care method to ... Method(R) and teach sufferers of jaw and facial pain new ways of using their muscles. When practiced ... regularity, these easy, DIY-exercises can relieve pain and improve posture. Dr. Wildman explains: ...

Cadence Pharmaceuticals Submits Acetavance New Drug Application for the Treatment of Acute Pain and Fever

... acetaminophen), for the treatment of acute pain and fever in adults and children. If approved, ... pivotal clinical trial for the treatment of acute pain in patients following orthopedic surgery and one ... most widely used medication for the treatment of pain and fever in the United States and is available ...

Ferring Pharmaceuticals Unveils Six-Month Efficacy Data for EUFLEXXA(R) for the Treatment of Osteoarthritis Knee Pain

... Results Show Superior Decrease in pain Scores Compared to Saline PARSIPPANY, N.J., ... hyaluronate) was effective at decreasing the pain of knee osteoarthritis (OA) at 26 weeks. The ... EUFLEXXA (R) is superior to saline in decreasing pain at 26 weeks in patients with OA of the knee.(1) ...

Alexza Reports 2009 First Quarter Financial Results and Updates Clinical Pipeline Status

... efficacy endpoint for the trial is headache pain relief at 2 hours post-dose, using the standard ... efficacy endpoints for the trial include pain relief and other symptom assessments at various ... fentanyl) for the treatment of breakthrough pain and AZ-007 ( Staccato zaleplon) for the ...

Methadone Frequently Causes Menopausal Symptoms in Young Women

... weight gain, bone loss, bladder pain, decreased pain tolerance, hot flashes, and increased risk for ... severe hormonal suppression caused by narcotic pain medications. Despite this study, most methadone ... Oxycontin, Percocet, morphine and other opiate pain medications, seldom test or treat patients for ...

Arcion Therapeutics' Topical Pain Candidate, ARC-4558, Significantly Reduces Pain Caused by Diabetic Neuropathy

... -Clinical Data Presented at American pain Society Annual Meeting- BALTIMORE, May 7 ... stage biotechnology company that develops pain therapies, today announced the presentation of ... lead candidate, ARC-4558, significantly reduced pain caused by diabetic neuropathy in a double-blind, ...

Three Clinical Presentations on Tapentadol Extended Release Tablets for Chronic Pain Featured at 2009 American Pain Society Annual Meeting

... DIEGO, May 7 /PRNewswire-USNewswire/ -- Chronic pain is a significant medical challenge in the United States, and chronic low back pain is the most common cause of disability in ... 100 million Americans suffer from chronic pain each year. If left undertreated, ...

AcelRx Initiates a Phase 2 Study to Evaluate Functionality of Its ARX-01 Sufentanil NanoTab PCA System

... developed for management of acute post-operative pain in the hospital setting. The primary objective ... of the ARX-01 System for post-operative pain management in patients undergoing unilateral knee ... medical need in the management of post-operative pain by allowing patients to manage ...

Chronic Ankle Pain May Be More Than Just a Sprain

... is untreated or overlooked which prolongs the pain and the problem. "When patients injure their ... describe how in some cases chronic ankle pain may actually be the result of injuries to the ... injuries can include: Ankle pain that is not responding to treatment ...

NanoVibronix Receives Wound Healing Indications in Europe for its PainShield(TM) Device

... we have seen a dramatic diminishing of wound pain when pain was present." NanoVibronix CEO, Dr. Harold ... PainShield device for treatment of pain gained FDA clearance in October 2008. The Company ...

QRxPharma Successfully Completes Comparative Study for Dual-Opioid(TM) Pain Therapy

... Results demonstrated that MoxDuo(TM) IR reduces pain significantly more than its component doses; ... statistical significance in measures of decreased pain intensity with MoxDuo(TM) IR compared to its ... to morphine and oxycodone in managing acute pain during the first 24 hours following a scheduled ...

QuatRx Completes Enrollment of Ophena(TM)(Ospemifene Tablets) Final Pivotal Phase 3 Study in Women with Postmenopausal Vaginal Atrophy

... symptoms such as dryness, irritation and sexual pain (dyspareunia). The first Phase 3 trial for ... by symptoms including vaginal dryness, sexual pain (dyspareunia) and irritation. Declining estrogen ... with reductions in vaginal secretions often cause pain or bleeding during sexual intercourse. It is ...

Neurocrine Announces Top-Line Results From 702 Study (Lilac PETAL Study) of Elagolix for Treatment of Endometriosis Pain

... The Lilac PETAL study assessed endometriosis pain through a variety of measures, several of which ... diary: a numeric rating scale (NRS) for pain (scale 0-10); a dysmenorrhea pain assessment (scale 0-3); and a non-menstrual ...

New Study Shows Probiotic Strain Effective in Improving Irritable Bowel Syndrome Symptoms

... coagulans significantly reduces abdominal pain and bloating CLEVELAND, March 24 ... PTA-6086 was effective in relieving abdominal pain and bloating in subjects with irritable bowel ... statistically significant reductions in abdominal pain and bloating versus baseline at each of the ...

Following Encouraging Results Anthera to Continue IMPACTS Trial for the Prevention of Acute Chest Syndrome in Patients With Sickle Cell Disease

... acute chest syndrome based on the combination of pain (vaso-occlusive crisis)¿ fever¿ and elevated ... ACS is a heart condition characterized by chest pain occurring at rest or upon minimal exertion. This ... referred to as unstable angina. If the chest pain is associated with heart muscle damage and heart ...

DURECT Reports Positive Phase IIb Data from TRANSDU(TM)-Sufentanil Clinical Program

... while also showing a reduction in pain scores on our therapy," stated James Brown, ... patch would compete effectively in the chronic pain market including both patches and oral opioids." ... administration at a dose delivering adequate pain control. Design ...

FDA Accepts Complete Response Submission to New Drug Application for NEBIDO(R)

... LIDODERM(R), a topical patch to relieve the pain of postherpetic neuralgia; PERCOCET(R) and ... for the relief of moderate-to-severe acute pain where the use of an opioid is appropriate; OPANA(R) ER tablets for the relief of moderate-to-severe pain in patients requiring continuous, ...