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Oxygen in Medical Technology

FDA Advisory Panel Recommends Approval of the SEDASYS(R) System

... System experienced fewer and less significant oxygen desaturation events, a clinical sign of ... of critical patient vital signs, including oxygen saturation, respiratory rate, heart rate, blood ... or reducing delivery of propofol, increasing oxygen delivery and automatically instructing patients ...

New NIH-Funded Study Shows Masimo Rainbow SET(R) May Help Clinicians Assess Oxygenation in Children With Sickle Cell Disease

... hypoxemia-a potentially life-threatening lack of oxygen in the blood-in children with sickle cell ... red blood cells that compromise vital blood and oxygen supply to the tissues and organs, causing ... in a sickle cell patient's blood reduces oxygen supply further because these dyshemoglobins that ...

U.S. Naval Medical Research Center Proposed 'RESUS' Clinical Trial in Trauma Patients Remains on FDA Hold

... it may not initiate a clinical trial of Biopure's oxygen therapeutic Hemopure(R) [hemoglobin glutamer -- ... manufactures and markets pharmaceuticals, called oxygen therapeutics that are intravenously administered to deliver oxygen to the body's tissues. Hemopure(R) [hemoglobin ...

U.S. Naval Medical Research Center Resubmits IND Application for Proposed 'RESUS' Clinical Trial in Trauma Patients in the Out-of-Hospital Setting

... to conduct a clinical trial of the company's oxygen therapeutic Hemopure(R) [hemoglobin glutamer - ... manufactures and markets pharmaceuticals, called oxygen therapeutics that are intravenously administered to deliver oxygen to the body's tissues. Hemopure(R) [hemoglobin ...

Oxygen Biotherapeutics, Inc. Receives Letter From FDA Outlining Path Forward to Resume Oxycyte Clinical Trials in TBI in U.S.A.

... MESA, Calif., March 19 /PRNewswire-FirstCall/ -- oxygen Biotherapeutics, Inc. (OTC Bulletin Board: OXBO) ... the company's perfluorocarbon (PFC) therapeutic oxygen carrier. The letter was in response to the ... the needs of all our stakeholders." About oxygen Biotherapeutics, Inc. ...

Oridion Announces Significant Medical Studies Presented at STA

... dioxide (EtC02), Respiratory Rate, Pulse Rate and oxygen saturation (SpO2) to provide a clear ... other tested CO2 sampling lines with and without oxygen supply, when sampling from nose and mouth ... to assessing the interactions of heart rate, oxygen saturation, respiratory rate and adequacy of ...

U.S. Naval Medical Research Center Resubmits IND Application for Proposed 'Op RESUS' Clinical Trial in Trauma Patients in the Battlefield Setting

... to conduct a clinical trial of the company's oxygen therapeutic Hemopure(R) [hemoglobin glutamer - ... manufactures and markets pharmaceuticals, called oxygen therapeutics that are intravenously administered ... glutamer - 200 (bovine)], or HBOC-301, the only oxygen therapeutic approved for marketing by both the ...

Seahorse Bioscience Announces the XF96 Extracellular Flux Analyzer for Cellular Bioenergetics

... for the kinetic measurement of mitochondrial oxygen consumption and cytoplasmic glycolysis in cells ... in 1932 and Leland Clark invented the Clark oxygen electrode in 1959. "Without oxygen consumption measurements, the study of ...

Battelle Scientists Named on Patent for Making Oxygen From Light and Water

... from Battelle has earned a patent for generating oxygen in a process that mimics photosynthesis. The technology creates oxygen and controls carbon dioxide using light energy ... and electrons from water and makes molecular oxygen without producing hydrogen gas. Then, the protons ...

Diffusion Pharmaceuticals Announces Initiation of a Phase I/II Clinical Trial in Patients with Peripheral Arterial Disease (PAD)

... to the treatment of conditions characterized by oxygen deprivation (hypoxia) at the cellular level. ... of action, TSC enhances the diffusion of oxygen through blood plasma, increasing the rate of oxygen transport and thus treating the symptoms of ...

K-State Researchers Awarded Nearly $1 Million to Test Remedies, Investigate Link Between E. Coli and Distillers' Grains

... of 160 F. The color of meat depends on the oxygen in the muscle cells, Hunt said. As an example, he ... oxygen, which causes the color to change. The oxygen in the muscle is carried by myoglobin, which is similar to hemoglobin that carries oxygen in humans. Observations during the study ...

Biopure Announces Meeting With FDA

... Biopure CEO and President. "By serving as an oxygen delivery bridge following chemotherapy-induced ... manufactures and markets pharmaceuticals, called oxygen therapeutics that are intravenously administered ... glutamer - 200 (bovine)], or HBOC-301, the only oxygen therapeutic approved for marketing by both the ...

Biopure Phase III Orthopedic Trial Results Published in Journal of Trauma

... the crossover patients had a greater need for an oxygen carrier, likely related to patient age, volume ... manufactures and markets pharmaceuticals, called oxygen therapeutics, that are intravenously administered ... glutamer - 200 bovine)], or HBOC-301, the only oxygen therapeutic approved for marketing by both the ...

Pivotal Study Shows Physician/Nurse Teams Using SEDASYS(TM) System Reduced Risk of Over Sedation With Propofol

... System experienced fewer and less significant oxygen desaturation events, a clinical sign of over ... primary endpoint of Area Under the Curve (AUC) of oxygen desaturation (SpO2 < 90%). AUC is an ... incorporates incidence, duration and depth of oxygen desaturation. Patients in the SEDASYS(TM) System ...

Biopure Announces Publication of Phase II Proof-of-Concept Coronary Trial

... trial to evaluate haemoglobin based oxygen therapeutics in elective percutaneous coronary ... this trial, we believe that Hemopure could be an oxygen bridge to prevent permanent myocardial damage ... in an acute setting, HBOC-201 could serve as an oxygen bridge to reperfusion by percutaneous coronary ...

Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack

... coronary arteries. The temporary absence of oxygen and nutrients from blood creates a condition in ... stress, caused by the production of reactive oxygen species. Reperfusion injury is due in part to the ... damage. The restored blood flow reintroduces oxygen within cells that damages cellular proteins, DNA, ...

Sangart Completes Enrollment in Phase III Study of Its Novel Blood Substitute Hemospan

... demand for a safe and effective agent to improve oxygen transport in clinical settings where blood is ... to be completed in the near future. No similar oxygen transport agents are currently on the market ... clinical studies indicate that Hemospan's novel oxygen delivery mechanism has the potential to provide ...

Independent Data Safety Monitoring Board Recommends Continuation of Sangart's Pivotal Phase III Trials of Hemospan(R) Following Second Interim Review

... research, development and commercialization of oxygen transport agents, today announced that ... CEO of Sangart. Hemospan is a hemoglobin-based oxygen transport agent designed to serve as an oxygen therapeutic and as an alternative to blood ...

New Clinical Studies Presented at the 14th World Congress of Anesthesiology Demonstrate Masimo Advancements in Patient Care

... total hemoglobin (SpHb(TM)) and oxygen content (SpOC(TM)) as part of the Rainbow SET ... in Toronto, Canada, said, "Accurate monitoring of oxygen saturations in children with cyanotic congenital ... noninvasive total hemoglobin (SpHb) and oxygen content (SpOC) as part of the Rainbow ...

Oxygen Relieves IBS and Constipation Symptoms in New Clinical Studies

... of recent clinical studies indicating their oxygen colon cleanser is extremely successful at ... failure rate. Colon cleansing with an oxygen colon cleanser is likely to become the new ... CEO and head of product development, says using oxygen to colon cleanse is the best thing a person can ...

Sangart, Inc. Initiates Dosing in Phase II Study of Hemospan(R) in Chronic Critical Limb Ischemia

... research, development and commercialization of oxygen transport agents, announced today that it ... CEO of Sangart. Hemospan is a hemoglobin-based oxygen transport agent designed to serve as an oxygen therapeutic and as an alternative to blood ...

New Study: Pine Bark Extract Boosts Nitric Oxide (NO) Production

... blood flow, muscle oxygen supply HOBOKEN, N.J., Oct. 17 /PRNewswire/ -- A ... which leads to an increase in blood flow and oxygen supply to muscles. Nitric oxide, a key ... flow that serves to deliver more nutrients and oxygen to the muscles, helping muscles to cope with ...

Researchers Report First Successful Treatment of Chronic Traumatic Brain Injury

... a new application and drug dosage of hyperbaric oxygen therapy. Hyperbaric oxygen therapy has been applied to diving injuries, ... Orleans, and author of recently published The oxygen Revolution (Hatherleigh Press, NY), said that he ...

Diabetes Research Institute Invention Promotes Growth of Stem Cells into Insulin-Producing Cells

... know that islets require a high amount of oxygen for optimal health, so UM researchers created a ... provide the cells with a more natural oxygen environment than those used in traditional ... stem cells, we were able to show that delivering oxygen in a physiological way enhanced enormously ...

Biopure Announces 2007 Third Quarter Financial Results

... Phase 2 out-of-hospital trauma study of Biopure's oxygen therapeutic Hemopure. In a recent letter to the ... function and/or wound healing by transporting oxygen through constricted or partially blocked arteries ... manufactures and markets pharmaceuticals, called oxygen therapeutics, that are intravenously administered ...

New Studies Presented at European Society of Anaesthesia Further Validate Masimo PVI(TM) for Noninvasive and Continuous Fluid Monitoring

... including: noninvasive and continuous total hemoglobin (SpHb(TM)), oxygen content (SpOC(TM)), carboxyhemoglobin (SpCO(R)), methemoglobin (SpMet(R)), ... SET continuously and noninvasively measures total hemoglobin (SpHb(TM)), oxygen content (SpOC(TM)), carboxyhemoglobin (SpCO(R)), methemoglobin (SpMet(R)), ...

MedImmune Presents New Data Demonstrating Increased Risk for Medically Attended RSV in Late-Preterm Infants

... and that this risk is higher among infants exposed to supplemental oxygen or assisted ventilation during the neonatal period. These findings were ... characteristics evaluated included GA, infant sex, "small for GA" status, oxygen exposure variables, and hospital discharge during the RSV season. The ...

Data from Phase 2 Study of Peramivir in Patients Hospitalized with Influenza Presented at the XI International Symposium on Respiratory Viral Infections

... which is a composite endpoint comprised of normalization of temperature, oxygen saturation, respiratory rate, systolic blood pressure and heart rate. ... chronic lung disease, congestive heart failure, diabetes mellitus, low oxygen saturation, low blood pressure, or severity of illness requiring ...

Stents Can Treat - Not Just Prevent - Strokes, Suggests Early Research

... death in the U.S., stroke is called a brain attack because blood flow and oxygen to part of the brain is cut off. About 85 percent of strokes are ischemic, ... and are caused by a broken blood vessel. The lack of blood flow and oxygen to the site of the stroke causes the brain tissue to die. About a quarter ...

Synvista Therapeutics Announces First Dosing of SYI-2074 in Clinical Trial for Psoriasis

... activity (i.e., higher levels of oxidized lipids promote the creation of oxygen free radicals and reactive oxygen species (ROS), such as H2O2, which can promote inflammation). As ...

FDA Approves LUSEDRA(TM) (fospropofol disodium) Injection for Monitored Anesthesia Care (MAC) Sedation

... process for early signs of hypotension, apnea, airway obstruction, and/or oxygen desaturation. Facilities for providing cardiopulmonary resuscitation must ... minutes in bronchoscopy patients. The use of supplemental oxygen is recommended in all patients receiving LUSEDRA. Airway assistance ...

Studies Examine Quality of Care for Hospitalized Sickle Cell Disease Patients and Effective Methods for Detecting Risk of Stroke in Children With This Disorder

... determined that low hemoglobin saturation (a decrease in the amount of oxygen in the blood) may predispose children with sickle cell disease to having a stroke by limiting oxygen delivery to the brain. Since hemoglobin saturation can be easily measured, ...

Light Sciences Oncology Completes Patient Enrollment in Phase 3 Clinical Trial of Litx as a Treatment for Hepatocellular Carcinoma

... molecule of LS11 many times, resulting in a continuous supply of singlet oxygen molecules. The Litx device contains a tiny array of LEDs at the ... closes tumor blood supply vessels, starving remaining cancer cells of oxygen and nutrients. The use of multiple light sources and multiple treatments ...

'Hibernation-On-Demand' Drug Hydrogen Sulfide Significantly Improves Survival After Extreme Blood Loss

... loss? One possibility is that in reducing metabolism, H2S also reduces oxygen demand, which allows crucial neurons in the hippocampus, the part of the ... autonomic functions such as breathing and heartbeat, to withstand low oxygen levels due to hemorrhage. Another mechanism may be that hydrogen ...

U.S. Navy Submits Protocol for Field Trauma Trial of Hemopure(R)

... Corporation develops, manufactures and markets pharmaceuticals, called oxygen therapeutics that are intravenously administered to deliver oxygen to the ... Oxyglobin(R) [hemoglobin glutamer - 200 (bovine)], or HBOC-301, the only oxygen therapeutic approved for marketing by both the U.S. Food and Drug ...

Alliance Pharmaceutical Corp. Announces Approval of Proposed Actions at Annual Shareholders Meeting

... technology. Oxygent is being developed as an intravascular oxygen carrier designed to augment oxygen delivery in surgical patients. Except for historical information, the ...

Nuvelo Begins Phase 2 Trial and Receives Fast Track Status for Alfimeprase in Patients With Acute Ischemic Stroke

... someone dies of one. A stroke occurs when a blood vessel that carries oxygen and nutrients to the brain becomes blocked by a blood clot (ischemic stroke) or ruptures (hemorrhagic stroke). This interruption in the blood and oxygen supply, to part of the brain, results in cell death and loss of function. ...

Alliance Pharmaceutical Corp. Updates Oxygent(TM) Clinical Development Plan

... proprietary PFC technology. Oxygent is being developed as an intravascular oxygen carrier designed to augment oxygen delivery in surgical patients. Except for historical information, the ...

Michael J. Fox Foundation Awards Over $2 Million for Validation of 10 Parkinson's Therapeutic Targets

... p eroxidase J. Timothy Greenamyre, MD, PhD, University of Pittsburgh Validation of Nox1/Rac1, a novel molecular source of reactive oxygen species in the nigrostriatal pathway, as a target for Parkinson ' s disease therapy Yoon-Seong Kim, MD, PhD, Weill Medical College of Cornell ...

GNC Unveils Study Results for First and Only Nitric Oxide Product Clinically Proven to Improve Physical Performance at NSCA Conference in Las Vegas

... This product is designed to increase nitric oxide levels in the body causing a hemodilation effect which expands blood vessels, allowing more blood, oxygen and nutrients to flow to muscles. "This is truly groundbreaking research that has resulted in the delivery of a truly novel and ...
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