Labopharm files New Drug Submission with Health Canada for novel antidepressant
... was no different from placebo. The overall drop out
rate in the study was 25 percent. The drop out
rate was 21 percent in the placebo group and 30 ... treatment due to somnolence or sedation. The drop out
rate observed in this study is comparable to ...
Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology
... (Geurts, et al.) scientists used ZFNs to knock out
an inserted reporter gene and two native rat ... sequence. Previously, ZFNs were used to knock out
specific genes in fruit flies, worms, cultured ... antibody platform, used Sangamo's ZFNs to knock out
the gene encoding rat immunoglobulin M (IgM), an ...
Pixantrone Produces High Rates of Complete and Partial Remissions Even Among Aggressive NHL Patients With Extensive Prior Doxorubicin Treatment or Prior Rituximab Treatment
... the comparator arm, the response rate was seven out
of 39 patients (18%) with three CRu.
The ... patients treated with standard chemotherapy (14 out
of 70 patients (20.0%) for the pixantrone arm compared to four out
of 70 patients (5.7%) for the standard ...
Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types
... from the investigator-driven study show that five out
of five patients evaluable for responses showed either partial responses to Gleevec (3 out
of 5) or stable disease (2 out
of 5). Responses in two of the three patients are ...
CDC Analysis Finds Unique Social and Behavior Intervention Helps Reduce MRSA Rates Up to 62% in Study Hospitals
... all staff members find the best ways to carry out
these goals and identify and eliminate barriers ... of his soiled gloves and gown. The escort figured out
that by quickly sliding out
of the gown, inverting it, folding it tightly and ...
DURECT Reports Positive Phase IIb Data from TRANSDU(TM)-Sufentanil Clinical Program
In this study, approximately half (36 out
of 74) of the screened patients successfully ... intention-to-treat patients set. Only 1 patient out
of 36 (approximately 2.8%) dropped out
of the study during the maintenance period for ...
The Children's Hospital of Philadelphia: New Gene-Searching Method Uncovers Possible New Targets for Crohn's Disease Drugs
... to each other by fine threads, you might pull out
clumps of them together.
Using a novel ... the power of gene discovery studies to ferret out
potential targets for disease treatments.
In ... team created a pathway-based approach that seeks out
interacting or related genes along the same ...
News Media Advisory: World's Leading Surgical Oncologists to Gather at McLaren Regional Medical Center to Present Latest Work on Breast, Gastrointestinal Cancer Treatments
... health systems in Michigan. To find out
more about MRMC, visit
... throughout the McLaren network.
To find out
more about GLCI, visit http://www.glci.com .
... HMO are also a part of the
system. To find out
more about how we're changing the future of ...
Battelle Scientists Named on Patent for Making Oxygen From Light and Water
... of the technology. "It adds oxygen and
Astronauts will have plenty of oxygen and ... When miners are trapped or a submarine runs out
breathable air, PDEC products could one day ... keep them alive by
providing oxygen and scrubbing out
Battelle scientists predict ...
Survey Shows Parents' Best Intentions Out of Step with Expert Recommendations in Protecting Kids from Flu
... about flu vaccine options.
Overall, about two out
of three parents (67 percent) surveyed say ... without having to get a shot, and
about three out
of four school-age children (77 percent) say the ... their child
vaccinated against the flu, nearly 4 out
of 5 (78 percent) say they would
be extremely or ...
AstraZeneca Announces Innovative New Partnership With Singapore Institutions to Develop Anti-Cancer Compounds
... compounds. The collaboration, which is spelt out
Memorandum of Understanding (MOU) that was ... Executive Officer, Dr. Lim Suet
Wun says, "165 out
of 1,069 ongoing research studies in NHG focus ... of cancer. Our large
base has allowed us to carry out
meaningful and effective clinical trials."
New AVAC Report on Pre-Exposure Prophylaxis Calls for Immediate Planning to Anticipate Study Results of Potential New HIV Prevention Option
... about ongoing and planned PrEP research, and lays out
for action on key issues that must be ... in some populations and is being
in some African countries.
"Although still ... now. This plan should
address the issues set out
in a Lancet paper of July 2007, which called ...
More Than 300 New Medicines Being Developed for Mental Illnesses
... know that there are many
new, potential options out
there that could allow them a better quality ... thinks they may have a mental illness -- to find out
the options are and seek treatment. People ... from
the public, Pantoliano has chosen to speak out
about his disease, and
founded the organization ...
New Data Shows 45 Percent of Patients with Stage 1 Hypertension Reached Normotension with BENICAR(R) and BENICAR HCT(R)
... (< 120/80 mm Hg) (placebo:1.4%).
- Eight out
of 10 (cumulative 81%) patients with stage 1 ... BENICAR HCT (placebo: 43.1%).
- Six out
of 10 (cumulative 60.3%) patients with stage 1 ... demonstrated in a sub analysis that eight out
of ten (cumulative
81%) patients with stage 1 ...
White Nose Syndrome: Is Pennsylvania Next?
... and the U.S. Fish and Wildlife Service to sort out
what is killing
bats in New York and New ... now and it doesn't look like we're going to find out
Nothing like this has been ... sources of additional funding to help
states sort out
what's happening within their borders. It also ...
STAR Cranial Centers of Excellence Offer Cutting-Edge Treatment to Dallas Area Children
... were worth it.
"People told me to wait it out
because they thought Christian's head
would grow ... cute. I was not embarrassed."
Aguilar pointed out
that the helmet had an unexpected benefit for ... Reed said. "Zoe did great. After she was out
helmet, I realize that we did spend a lot ...
Study Results of GAMMAGARD S/D and GAMMAGARD LIQUID in Patients with Mild-to-Moderate Alzheimer's Disease Announced
... study provided encouragement to carry out
a Phase III trial. The
criteria for going forward ... earlier Phase I study in eight patients
at New York-Presbyterian/Weill Cornell that was ... in the study it was
preserved or improved in 10 out
of 13 patients after six months of
GAMMAGARD S/D ...
Mayo Clinic Studies Find REM Sleep Behavior Disorder is Associated with Other Features of Neurodegenerative Disorders
... which often are unpleasant and violent. Acting out
by a loss of normal muscle paralysis in ... There are very few studies that have
been carried out
on RBD on a large scale. Plus, we currently ... Boeve and a team of Mayo Clinic physicians set out
whether cognitively-normal ...
PharmAthene's Recombinant Butyrylcholinesterase (rBChE) May Play A Neuroprotective Role in Alzheimer's Disease
... based on Hebrew University
technologies licensed out
by Yissum. Ranked among the top ... 5500 patents
covering 1600 inventions; licensed out
480 technologies and spun out
companies. Yissum's business partners span the ...
Major Deficiencies in Design; Funding of Clinical Trials Affects Future of Scientific Innovation
... in the way clinical trials are designed, carried out
funded in the U.S. with serious implications ... goal of human studies, the EDICT review
the under-representation of women, older people, ... of age.
Older Americans are also routinely left out
of clinical trials studying
diseases associated ...
Sangamo BioSciences and Sigma-Aldrich Announce Publication of Study Demonstrating Zinc Finger Technology for Rapid Generation of 'Knock-Out' Cell Lines
This work, which was carried out
in collaboration with scientists from
Pfizer Inc, ... Unit. "In addition to reagents for
an investigator's 'favorite gene' in a particular ... we
have used these same techniques for knocking out
genes in multiple crop
plants and to develop ZFP ...
Nobel Prize-Winning Discovery
... stem cells can be inherited.
Want to figure out
what role a certain gene plays in susceptibility ... disorder devastates multiple organ systems in one out
3,700 babies born in the United States, ... functions. Eventually, this could
mean knocking out
cystic fibrosis and other inherited disorders.
Kosan Presents Updated Data on Hsp90 Inhibitor, Tanespimycin, in Multiple Myeloma at Ash
... bortezomib dose 2 times per week every 2
of 3 weeks.
A total of 71 patients were ... and minor responses) was 47% (9 out
of 19 evaluable patients),
including 2 complete ... the tanespimycin injection (45%, 5 out
of 11 patients; 2 CR, 1 PR,
2 MR) and the ...
Interview of the Vice President
... a Speaker who, from my
perspective, is that far out
of the sort of mainstream -- she is a ... attacks as a law
enforcement problem. We went out
and arrested the bad guy, put him on
trial, ... attacks on the World Trade Center is doing life out
Colorado. That was the old way of looking at ...
Bristol-Myers Squibb, New Jersey Children's Hospital Launch Center for Immune System Disorders & Infectious Diseases Including HIV/AIDS
... which promoted awareness of
Bristol-Myers Squibb also joined with ... of New Jersey (HINJ), in supporting Reach out
and Read programs
at various New Jersey ... children's literacy
program modeled on the Reach out
and Read program at one of its ...
NicOx Announces TOPIGEN Initiates Phase 2 Proof of Concept Study in COPD for TPI 1020
... assess the
volume of air that can be moved in and out
of the lungs. The three
parameters which will be ... 1 (FEV1), the volume of air that can be breathed out
first second of forced exhalation; ... of air
that can be breathed in after breathing out
normally. Blood cells and
cytokines will also be ...
FORTEO(R) Increased Spine Bone Mineral Density in Patients with Glucocorticoid-Induced Osteoporosis
... that glucocorticoids are used by up to three out
of every 100
adults (3 percent) over age 50,(3) ... patient receiving teriparatide (0.6 percent; 1 out
of 171 patients) and 10 patients receiving alendronate (6.1 percent; 10 out
of 165 patients) had greater than or equal ...
Positive Five-Year Safety Data for TAXUS(R) Stent Reported in Boston Scientific Trial
... as evidenced by clinical trial data
now reporting out
to five years," said Paul LaViolette, Chief ... preventing restenosis, or additional procedures, out
to five years
across a wide variety of patients ... offerings.
If our underlying assumptions turn out
to be incorrect, or if certain risks
Abbott's XIENCE(TM) V Everolimus Eluting Coronary Stent Shows Continued Superiority to TAXUS Stent in Reducing Major Adverse Cardiac Events in SPIRIT III Clinical Trial
... thrombosis rates between XIENCE V and TAXUS out
to one year. "To date, XIENCE V is the only ... rates of
stent thrombosis for XIENCE V or TAXUS out
to one year in the SPIRIT III
trial. Rates of ... event at
one year and no additional MACE events out
to three years. In addition, the
number of late ...
38.7 Million People Break Guinness World Record for Stand Up Speak Out on International Day for the Eradication of Poverty
... of the Millennium Development Goals. They spoke out
to demand a
more urgent political response to the ... the Occupied West Bank and Gaza spoke out
saying no to poverty. The activities organized ... human chain. -- Faith leaders Stand Up and Speak out
-- At papal mass at the Vatican Pope Benedict ...
New Risk Gene for Rheumatoid Arthritis and Lupus Opens Door to More Effective Treatments
"We now are faced with trying to figure out
how this variant of STAT4
increases a person's ... of
volunteers, we will have more power to pull out
additional new genes and
what they do in triggering these diseases. ...
Kosan Receives Completed Special Protocol Assessment for TIME-1 Pivotal Phase 3 Trial of Tanespimycin in Multiple Myeloma
... bortezomib dose
2 times per week every 2 weeks out
of 3 weeks). Of these 56 patients, all
had ... responses was, as previously
reported, 44% (18 out
of 41 patients evaluable for response). Of the 18
responding patients (44%), 8 out
of 14 patients were bortezomib-nave
Study Confirms Limited Human-To-Human Spread of Avian-Flu Virus in Indonesia in 2006
... and then just stopped, but it could have gotten out
The world really may have dodged a ... and other
public-health officials, to carry that out
efficiently," Halloran said.
"The manuals on how ... said. If a smoldering disease cluster does flame out
of control, the software
also could be used to ...
Kosan Opens Registration Program for Lead Hsp90 Inhibitor, Tanespimycin, in Multiple Myeloma
... bortezomib dose
2 times per week every 2 weeks out
of 3 weeks). Of these 56 patients, all
had ... responses was, as previously
reported, 44% (18 out
of 41 patients evaluable for response). Of the ... of 14 patients were bortezomib-nave (57%); 7 out
of 16 patients were
R-Tech Ueno, Ltd. Completes Phase 1 Clinical Study on RK-023
... study, 2 ml of RK-023 preparation was applied to the vertex region of 6 out
of 9 healthy adult males and a placebo to that of the remaining 3 ... night 2 ml of RK-023 preparation or 2 ml of placebo was applied to 6 and 2 out
of 8 healthy adult males respectively. No serious adverse event was ...
Results From Drug Trials and New Risk Factors Announced at International Alzheimer's Conference
... your risk of developing Alzheimer's disease or another dementia. Find out
more by visiting the Alzheimer's Association at www.alz.org.
... a Clinical Studies Initiative to begin to address this problem. Find out
more at 1-800-272-3900 or www.alz.org.
About ICAD 2009
AcelRx Announces Positive Phase 2 Results from a Study of ARX-01 Sufentanil NanoTabs in Treating Post-Operative Pain
... a minimum re-dosing interval of 20 minutes. Patients were allowed to drop out
of the study at any time. The primary efficacy endpoint was SPID-12 (a ... carried forward). Additionally, the proportion of patients who dropped out
due to inadequate analgesia, a clinically meaningful secondary endpoint, ...
China Animal Welfare Law Under Review While 36,000 Dogs Culled
... a death toll of 36,000. Claiming rabies outbreak, the city has sent out
dog-beating squads to kill any animal spotted on the street, stray or ... welfare organizations, IFAW has representation in 16 countries and carries out
its animal welfare work in more than 40. IFAW works from its global ...
Micromet Presents Update on Blinatumomab's Response Rate and Duration in a Phase 1 Study in Non-Hodgkin's Lymphoma Patients
... is a novel therapeutic antibody that activates a patient's T cells to seek out
and destroy cancer cells.
The poster presentation gave an update of ... treatment with single agent blinatumomab(2). The data show that 11 out
of 12 patients having received a dose of 0.06 mg/m(2) per day during the ...
Afinitor(R) Phase II Data Show Positive Results for Patients With Multiple Types of Lymphoma, Leading to Phase III Trial
... - Afinitor significantly reduced tumor size by 50% or more in one out
of three patients with refractory or relapsed lymphoma
- Phase III ... lymphoid tissue, lymph vessels and lymph fluid that help the body filter out
bacteria and fight disease. Since lymphatic tissue is located throughout ...