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Obesity in Medical Technology

Spherix Announces Positive Phase 2 Study Results

... vs. D-tagatose in hypercholesterolemic mice. obesity . 2009 Feb;17(2):269-75.). A novel finding in ... with and without type 2 diabetes. Diabetes obesity Metab 1999 I 5 285-291) A dose and ... and Obesity-Control Drug. Diabetes, obesity and Metabolism . 10 , 2008, 109-134.) ...

Isis Highlights New Data on Antisense Drugs to Treat Type 2 Diabetes and Obesity at ADA Scientific Sessions

... animals, Isis also presented data from its obesity drug discovery program. In an oral presentation, ... unique therapeutic approach for the treatment of obesity and related metabolic disorders. "We are ... Association With Insulin Resistance and obesity and PKC-alpha Mediated Regulation by ...

Arena Pharmaceuticals Announces Lorcaserin Data Demonstrating Highly Significant Categorical and Absolute Weight Loss and Improvements in Secondary Endpoints Associated with Cardiovascular Risk

... modification and Lorcaserin for Overweight and obesity Management), the first of two pivotal trials ... modification and LOrcaserin Second Study for obesity Management), the integrated data set from the two ... modification and Lorcaserin for Overweight and obesity Management in Diabetes Mellitus), and is planned ...

Arena Pharmaceuticals Announces the Presentation of Lorcaserin Phase 3 BLOOM Data at the American Diabetes Association's 69th Scientific Sessions

... modification and Lorcaserin for Overweight and obesity Management) trial has been accepted for a poster ... Modification and Lorcaserin for Overweight and obesity Management, the BLOOM Trial," will be displayed ... presentation number 96-LB in category 20-B obesity - Clinical Treatment. Steven R. Smith, M.D., ...

New Research Shows Nutrition 21's Chromium Histidinate Improves Markers for Mood and Carbohydrate Cravings

... its chromium histidinate in animal models of obesity and of diabetes. The addition of chromium ... not cause kidney dysfunction in animal models of obesity and of diabetes. James Komorowski, M.S., ... of our chromium products in conditions such as obesity and diabetes, and begins to demonstrate the ...

Results From Phase 3 EQUATE Trial of VIVUS' Qnexa Highlighted at European Congress on Obesity

... today at the 17th annual European Congress on obesity (ECO) in Amsterdam, The Netherlands. The results, ... weight loss seen across our phase 2 and phase 3 obesity and diabetes Qnexa trials to date, coupled with ... represents a step forward in the treatment of obesity and obesity-related conditions," commented Leland ...

Mayo Clinic: Retired National Football League Linemen Have High Incidence of Sleep Apnea

... In addition, researchers discovered that age and obesity (measured by the body mass index, which corrects ... noted that the prevalence of sleep apnea and obesity was higher than expected, and serves as a warning ... for cardiac disease, and may be linked to both obesity and sleep apnea," Dr. Somers says. Retired ...

Genaera Presents Promising Preclinical Data for Trodusquemine (MSI-1436) at Keystone Symposia

... and obesity, during the Keystone Symposia: obesity - Novel Aspects of the Regulation of Body Weight ... and metabolic outcomes associated with both obesity and diabetes," commented Jack Armstrong, ... ability to reverse co-morbidities associated with obesity such as abnormal glucose metabolism and ...

Major deCODE-led Study Underscores Role of the Brain in Obesity

... and replicated genetic factors contributing to obesity as a public health problem. And what we are seeing in obesity are a large number of common genetic risk factors ... obesity," Dr. Stefansson added. About obesity and this study ...

Orexigen(R) Therapeutics Announces Changes to Its Clinical Programs and Management Team

... resources, focus its efforts on its late-stage obesity programs and realign its management team. ... the need to focus our resources on our late-stage obesity programs," said Eckard Weber, M.D., the Company's ... and resources to Contrave(R) and Empatic(TM), its obesity product candidates. It anticipates ...

Genaera Begins Phase 1b Trial of Trodusquemine (MSI-1436) in Overweight and Obese Type 2 Diabetics

... for the treatment of type 2 diabetes and obesity which works centrally and peripherally to ... treatment for both type 2 diabetes and obesity with a single drug," said Jack Armstrong, ... ability to reverse co-morbidities associated with obesity such as abnormal glucose metabolism and ...

New Analysis Shows Troubling Trend in Triglyceride Levels May Be Linked to Rising Rates of Obesity

... Data indicate a strong correlation between obesity (defined as a BMI greater than or equal to 30 kg/m2) and high triglycerides. Rates of obesity more than doubled from 15 percent in 1976 to 33.7 ... 30 years. "As Americans age and rates of obesity continue to grow exponentially, it is becoming ...

Genaera Corporation Reports Phase 1 Data for Trodusquemine (MSI-1436) at the North American Association for the Study of Obesity Annual Meeting

... the North American Association for the Study of obesity (NAASO) Annual Meeting in Phoenix, Arizona. "We ... ability to reverse co-morbidities associated with obesity such as abnormal glucose metabolism and ... to redefine the treatment paradigm for obesity and type 2 diabetes and is presently in phase 1 ...

Amylin Pharmaceuticals to Present Novel Data on Promising Obesity Pipeline at 2008 Annual Scientific Meeting of The Obesity Society

... neurohormonal approach to obesity pharmacotherapy SAN DIEGO, Oct. 1 ... The Obesity Society in Phoenix October 3-7. The obesity Society's annual meeting is one of the largest ... showcasing progress in the company's obesity pipeline. In addition to Amylin's lead ...

Interleukin Genetics and Geisinger to Collaborate on Genetic Tests to Predict Weight Loss Success

... visit http://www.geisinger.org About obesity & Weight Management obesity has been defined by the National Institutes of ... and behavioral factors. Accordingly, treatment of obesity usually requires more than just dietary changes. ...

Genaera Releases Phase 1 Data and New Preclinical Data on the CNS Function of Trodusquemine (MSI-1436) at CBI Obesity Summit

... 2 diabetes and obesity, during the CBI 4th Annual obesity Drug Development Summit in Arlington, Virginia. ... a promising therapeutic candidate for both obesity and type 2 diabetes. "The data reported today ... ability to reverse co-morbidities associated with obesity such as abnormal glucose metabolism and ...

Genaera Corporation Presents Data on Mechanism of Inhibition of PTP-1B for Trodusquemine (MSI-1436) at Federation of American Societies for Experimental Biology (FASEB) Meeting

... as a therapeutic target for the treatment of obesity and type 2 diabetes has long been a goal of ... during treatment in preclinical models of obesity and diabetes with MSI-1436. To date, MSI-1436 ... ability to reverse co-morbidities associated with obesity such as abnormal glucose metabolism and ...

Orexigen(R) Initiates Second Phase IIb Empatic(TM) Trial on Schedule

... to address a broad spectrum of obesity patients SAN DIEGO, July 9 ... Empatic(TM), one of the Company's two late-stage obesity product candidates. The trial is designed to ... to be an important component of the Company's obesity program. Along with Contrave(R), now in Phase III ...

Genaera Corporation Presents Additional Promising Preclinical Type 2 Diabetes Data for Trodusquemine (MSI-1436) at American Diabetes Association

... useful for the treatment of type 2 diabetes and obesity in humans based on the marked improvements ... ability to reverse co-morbidities associated with obesity such as abnormal glucose metabolism and ... to redefine the treatment paradigm for obesity and type 2 diabetes and is presently in a phase 1 ...

Women Who Gain Excessive Weight During Pregnancy More Likely to Have Overweight Children

... for overweight. "The earliest determinants of obesity may operate during intrauterine life, and ... can have long-term consequences on the risk of obesity in children," said study leader Brian Wrotniak, ... weight gain and also help prevent obesity in their children. They add that benefits would ...

Grocery Manufacturers Association: Study Signals Progress in Battle Against Obesity

... in response to the findings on childhood and teen obesity rates reported in the latest issue of the Journal ... indicating that the rise in childhood and teen obesity rates has halted and we hope that these ... continue in their on-going efforts to help reduce obesity among our children and teens. "Today's findings ...

Amylin Pharmaceuticals Initiates Phase 2B Dose-Ranging Clinical Study of Pramlintide/Metreleptin Combination Treatment in Obesity

... part of an integrated neurohormonal approach to obesity pharmacotherapy." The scientific studies ... non-clinical experiments are relevant to human obesity and suggest that metreleptin may be an effective ... scientific journals. About Obesity obesity is a chronic disorder that affects millions of ...

Imaging Results From the ADAGIO-LIPIDS Reveal That Effects of Rimonabant on Cardiometabolic Risk Profile Include Loss of Visceral Fat and Mobilization of Liver Fat

... we now have evidence that patients with visceral obesity represent the subgroup of overweight/obese ... support to the notion that patients with visceral obesity who are often either dyslipidemic or with type 2 ... the Laval Hospital Research Center is to slow the obesity epidemic and the progression of cardiovascular ...

Gene Hunters Fine-Tune Marker for Common Obesity Gene

... important, family studies have indicated that obesity has a genetic component as well. The research ... was the only marker significantly linked to obesity among the African American children. Both ... that the gene may be primarily associated with obesity that begins in childhood. Future medical ...

American Heart Association Journal Report: Reducing Kids' Salt Intake May Lower Soft Drink Consumption, Reducing Obesity, High Blood Pressure and Later Health Risks

... soft drink consumption is related to obesity in young people. However, it is unclear whether ... consumption. "Both high blood pressure and obesity increase the risk of having strokes and heart ... to stop the nationwide increase in childhood obesity by 2010 and is taking bold, innovative steps to ...

Bone Mineral Content Continues to Increase in Obese Adolescents During Weight Loss

... A study in the current issue of the journal obesity studied 62 adolescents between the ages of nine ... very obese teenagers lose weight. In adults, obesity is associated with increased bone mineral ... despite weight loss. "The growing pediatric obesity epidemic raises important clinical and public ...

Genaera Announces Diabetes IND In Effect for Trodusquemine (MSI-1436)

... for the treatment of type 2 diabetes and obesity which acts by regulating insulin and leptin ... in type 2 diabetes, in addition to our ongoing obesity studies. With this dual strategy, we believe that ... 2 diabetics (study MSI-1436C-103) under Genaera's obesity IND. Additional phase 1 studies will explore the ...

FASgen Announces a New Discovery in Obesity Research

... of important new research results in the obesity field using FAS89B, one of the Company's ... disorders, specifically for the treatment of obesity and fatty liver disease. The Company has a ... of research into the field of treatment for obesity and fatty liver disease. About FASgen, Inc.: ...

LAP-BAND(R) System Weight-Loss Surgery Associated With More Than 70 Percent Reduced Risk of Death in People With Severe Obesity

... About Obesity In the United States, obesity is considered the second leading cause ... of Surgery and Head of the Centre for obesity Research and Education (CORE) at Monash ... NEJM. 2007;357:753-761. (7) American obesity Association. AOA Fact Sheets. Available at ...

New Risk Factor for Heart Disease Identified in Very Young Children, According to Study at American Heart Association Scientific Sessions

... study in a continuum of research on childhood obesity as a risk factor for heart disease in later life ... which have focused on the impact of childhood obesity on children's hearts, make a powerful case that there is a clear link between obesity in childhood and heart disease in later life. We ...

Obesity Common in Children with Heart Disease

... PHILADELPHIA, Nov. 1 /PRNewswire-USNewswire/ -- obesity is common in children with heart disease, a ... the researchers stress that health risks from obesity are added to the children's separate risks from ... may play a role in the development of obesity in this patient group, say the research team, ...

Obesity-Related Hormone is Higher in Children with Down Syndrome

... may contribute to the known higher risk of obesity among children and adults with Down syndrome. A ... the study, in order to focus on risk factors for obesity before obesity occurred. The children with Down syndrome had ...

Genaera Corporation Provides Highlights of Positive Phase 1 Trodusquemine (MSI-1436) Data from the North American Association for the Study of Obesity Annual Meeting

... the North American Association for the Study of obesity (NAASO) Annual Meeting in New Orleans: -- ... pathways in a mouse model of diet induced obesity (DIO). About Genaera Genaera Corporation is ... to redefine the treatment paradigm for obesity and type 2 diabetes and is presently in a Phase 1 ...

Genaera Corporation Presents Phase 1 Data for Trodusquemine (MSI-1436) at the North American Association for the Study of Obesity Annual Meeting

... the North American Association for the Study of obesity (NAASO) Annual Meeting in New Orleans, Louisiana. ... of clinical trials as we study patients with both obesity and type 2 diabetes so that we may potentially ... pathways in a mouse model of diet induced obesity (DIO). About Genaera Genaera Corporation is ...

Studies Show Body Mass Index Has No Effect on Resolution and Healing of GERD Symptoms

... reflux disease (GERD) and obesity has long been established, but healthcare ... patients with GERD. Two studies about obesity and its relationship to GERD were presented at ... a BMI greater than 30 kg/m(2) -- the cutoff for obesity -- face double the risk of developing GERD.(3) ...

Surgeons Find That Laparoscopic Banding Procedure Helps Overweight Adolescents Lose Weight and Improve Health

... an active role in researching new ways to reduce obesity rates in children. Evan Nadler, MD, and ... this is vastly underappreciated in my opinion. obesity is devastating to these children's social ... improved." According to Dr. Nadler, "Childhood obesity is a very controversial topic and probably the ...

Sarasota's Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes

... study defining a mechanism for the development of obesity and the metabolic syndrome, which are the ... excessive quantities of fat, causing abdominal obesity and alterations in blood lipids. According to the study, this can then lead to obesity and the metabolic syndrome, the precursors of ...

Genaera Corporation Presents Interim Phase 1 Data for Obesity Compound Trodusquemine (MSI-1436) at IBC Conference

... A Novel Aminosterol for the Treatment of obesity and Related Metabolic Disorders," during the IBC ... and provide proof of concept for trodusquemine in obesity and type 2 diabetes management," commented Jack ... for two of the most serious metabolic diseases, obesity and type 2 diabetes. In addition, trodusquemine ...

Cardax Pharmaceuticals Nominates Clinical Candidate Heptax for Liver Disease; Heptax Ameliorates Inflammation and Oxidative Stress Related to Liver Disease and Metabolic Syndrome

... Disease Control and Prevention reported this week that the prevalence of obesity among Americans is now over 26%. obesity exacerbates a constellation of diseases including diabetes, liver disease, ...

VIVUS Initiates Open Label Safety Study of Avanafil for Erectile Dysfunction

... in the second half of this year, including results from two phase 3 obesity trials of our lead product Qnexa as well as data from the REVIVE trial of ... is expected to complete phase 3 clinical trials for the treatment of obesity in 2009. Qnexa is also in phase 2 clinical development for the treatment ...
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