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Muscle in Medical Technology

Video: FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia

... usual, increased heart rate or blood pressure, or muscle pain or weakness. Treatment should be stopped if ... feeling of inner restlessness, and abnormal muscle movements, including tremor (shaking), shuffling, ... with two injections administered in the deltoid muscle one week apart (Day 1 at 234 mg and Day 8 at 156 ...

Leading Experts Endorse Bioheart's Muscle Stem Cell MyoCell Therapy

... phase of clinical trials (MARVEL) to advance muscle stem cell (myoblast) therapy for treating heart ... run. We were able to show that we could grow new muscle in the center of ischemic myocardium and improve ... that the cells survive, engraft and form new muscle and they do excrete fatigue resistant proteins ...

New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients

... fever, sweat, or chills muscle aches cough shortness of breath ... little or no appetite vomiting muscle aches dark urine clay-colored ... of the body, sensitivity to the sun, new joint or muscle pain, becoming very tired, chest pain or ...

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

... fever, sweat, or chills muscle aches cough shortness of breath ... little or no appetite vomiting muscle aches dark urine clay-colored ... of the body, sensitivity to the sun, new joint or muscle pain, becoming very tired, chest pain or ...

Celladon Provides MYDICAR(R) Program Update of First-In-Human Trial for Advanced Heart Failure at American Society of Gene Therapy Annual Meeting

... cycling and contractility in some of the heart muscle cells of these very sick patients," said ... of restoring SERCA2a enzyme activity in heart muscle cells. The enzyme levels are decreased in late ... vector that transfers the SERCA2a gene into heart muscle cells. MYDICAR is delivered in a single dose ...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

... nausea, cardiovascular ischemic events, muscle pain, osteoporosis, arthritis and bone fracture. ... superficial edema (60%-74%), nausea (50%-73%), muscle cramps (28%-62%), vomiting (23%-58%), diarrhea ... were mild nausea, vomiting, diarrhea, myalgia, muscle cramps, and rash, which were easily manageable. ...

Celladon Corporation Announces Presentation of First-in-Human Gene Transfer to Treat Heart Failure at the 12th Annual Meeting of the American Society of Gene Therapy

... is the depletion of SERCA2a enzyme in heart muscle cells, which results in abnormal intracellular ... SERCA2a enzyme production by means of cardiac muscle gene transfer. The path of investigation for ... calcium cycling and contractility in heart muscle cells. Celladon's first product candidate, ...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

... in pulse, heart rate, or blood pressure; or muscle pain and weakness. Treatment should be stopped ... are usually persistent movement disorders or muscle disturbances, such as restlessness, tremors, and muscle stiffness. If you observe any of these symptoms, ...

RAPAFLO(TM) (silodosin) Provides Rapid and Sustained Benign Prostatic Hyperplasia (BPH) Symptom Relief in as Little as Three Days

... symptoms appears to depend in part on smooth muscle tone in the prostate and bladder neck, which is ... effective relaxation of the targeted prostatic muscle tissue, with a low incidence of vasodilatory and ... for the alpha (1B) receptors that cause smooth muscle in peripheral vessels is significantly lower, ...

New Data for Abbott's TRILIPIX(R) (fenofibric acid) in Combination with Rosuvastatin Calcium Shows Improvement on Key Lipids for Cholesterol Management

... TRILIPIX alone. No unexpected liver, kidney or muscle safety issues were identified in this study. muscle related problems can occur with TRILIPIX and ... allergic to any product ingredient. Unexplained muscle pain, tenderness, or weakness, particularly when ...

Fast-Acting, Long-Lasting Topical Relief From Arthritis Pain

... inflammation, swelling, joint stiffness, muscle pain and range of motion. Throughout the study, ... and inflammation and a full 100% had relief from muscle pain and joint stiffness. All of the results were ... complete program to successfully manage joint and muscle pain. The cream provides fast, convenient relief ...

Impact Medical Solutions Announces Initiation of Pilot Clinical Trial and Listing on Frankfurt Stock Exchange

... proprietary information technology platform, muscle Pattern Recognition (MPR). MPR is a unique clinical tool that analyzes patterns of muscle recruitment and provides detailed physiological information on muscle function that can assist in the diagnosis and ...

Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Announces FDA Filings for Paliperidone Palmitate and INVEGA(R)

... in pulse, heart rate, or blood pressure; or muscle pain and weakness. Treatment should be stopped if ... are usually persistent movement disorders or muscle disturbances, such as restlessness, tremors, and muscle stiffness. If you observe any of these symptoms, ...

PTC Therapeutics Completes Enrollment of Pivotal Trial in Muscular Dystrophy

... determine whether ataluren can improve walking, muscle function and strength in patients with nmDMD/BMD. ... muscular dystrophy (DMD/BMD) are progressive muscle disorders that result in the loss of both muscle function and independence. DMD/BMD is perhaps ...

Impact Medical Solutions Announces Appointment of New Director and Corporate Update

... of its proprietary medical technology, the muscle Pattern Recognition (MPR) System. "The MPR ... on developing a proprietary platform called muscle Pattern Recognition (MPR), a unique clinical tool for the analysis of muscle function. MPR analyzes patterns ...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

... superficial edema (60%-74%), nausea (50%-73%), muscle cramps (28%-62%), vomiting (23%-58%), diarrhea ... nausea, cardiovascular ischemic events, muscle pain, osteoporosis, arthritis and bone fracture. ... occasionally incapacitating bone, joint and/or muscle pain has been reported infrequently in patients ...

Study Suggests Treatment with Paliperidone ER Significantly Improves Symptoms of Schizoaffective Disorder

... in pulse, heart rate, or blood pressure; or muscle pain and weakness. Treatment should be stopped if ... are usually persistent movement disorders or muscle disturbances, such as restlessness, tremors, and ... (for example, involuntary movements, tremors and muscle stiffness). (a) Mean modal dose for the higher ...

Video: Answer to Curing a Failing Heart May Exist in Body's Own 'Do-It-Yourself' Repair Kit

... Called MyoCell(R) muscle Stem Cell Therapy, the unique transplant procedure actually uses skeletal muscle stem cells (myoblasts) from the patient's own ... Further, myoblasts can be delivered to the heart muscle in a minimally invasive fashion via a catheter ...

Early Data Show Potential for Imatinib Mesylate Tablets to Treat Life-Threatening Form of Pulmonary Artery Disease

... In patients with PAH, PDGFR may cause smooth muscle cells in the pulmonary arteries to multiply, ... superficial edema (60%-74%), nausea (50%-73%), muscle cramps (28%-62%), vomiting (23%-58%), diarrhea ... assessed were nausea (57%); diarrhea and muscle cramps (43% each); anemia, fatigue, arthralgiaand ...

Bioheart Announces 35 Leading U.S. Heart Failure Centers Engaged in Phase II/III Marvel Trial of Myogenic Cells for Treating Advanced Heart Failure

... involves a physician removing a small amount of muscle obtained from the patient's thigh. From this muscle specimen, autologous myoblasts (muscle stem ... vascular surgeon. The myoblast-based muscle formation in the newly populated regions of scar ...

PTC Therapeutics Announces Data Showing Six-Minute Walk Test Consistently Measures Ambulatory Function in Patients With Duchenne Muscular Dystrophy

... Data Presented at the 13th International World muscle Society Congress - SOUTH PLAINFIELD, N.J., ... (DMD/BMD) at the 13th International World muscle Society (WMS) Congress. Results from an ... muscle disorders that cause the loss of both muscle function and independence. DMD/BMD is perhaps the ...

Schering-Plough Announces European Launch of BRIDION(R) (Sugammadex)

... for routine reversal of the commonly used muscle relaxants rocuronium or vecuronium and for ... reverse within minutes both moderate and deep muscle relaxation induced by rocuronium or vecuronium ... of procedures where these agents are used. A muscle relaxant plays several critical roles in general ...

Sangamo BioSciences Initiates Phase 2 Clinical Trial of Treatment for Amyotrophic Lateral Sclerosis (ALS)

... as well as promoting nerve, blood vessel and muscle growth. In ALS, the motor nerves comprised of ... of SB-509 in subjects with a motor neuron and muscle disease such as ALS is an obvious next step in ... (NI), a measure of neurologic impairment; Manual muscle Test (MMT), a test ...

BRIDION(R) (sugammadex) Injection - First and Only Selective Relaxant Binding Agent - Approved in European Union

... moderate and deep levels of muscle relaxation First product approval from the ... for routine reversal of the commonly used muscle relaxants rocuronium or vecuronium and for ... reverse within minutes both moderate and deep muscle relaxation induced by rocuronium or vecuronium ...

Bioheart Reports Promising Results From SDF-1 Modified MyoCell(R) Therapy in Heart Failure Study

... Pre-Clinical Data Shows Increased muscle and Blood Vessel Formation in ... myoblasts expressing SDF-1 resulted in increased muscle and blood vessel formation in the damaged areas ... involves a physician removing a small amount of muscle obtained from the patient's thigh. ...

International Team Locates Key Player in Muscle Regeneration

... of the role played by the protein cdk9-55 in muscle regeneration and differentiation may lead to novel therapies to rebuild muscle tissue damaged by disease, injury and aging, ... ). Adult skeletal muscle tissue can regenerate in response to ...

TorreyPines Therapeutics to Host Webinar at 11 a.m. EDT Today on the Opportunity for Treating Chronic Pain, Migraine and Muscle Spasticity Through Inhibition of Neurotransmitter Glutamate

... of treating chronic pain, migraine and muscle spasticity through the inhibition of ... receptors in the spinal cord as a target for muscle spasticity. He has served as Vice Chairman ... chronic pain such as neuropathic pain as well as muscle spasticity and rigidity secondary to spinal cord ...

Synapse Biomedical Receives FDA Approval of NeuRx Diaphragm Pacing System (DPS)(TM) For Spinal Cord Injury Breathing Applications

... surgery, provides electrical stimulation to muscle and nerves that run through the diaphragm. When ... and inserts a laparoscope so that the diaphragm muscle can be seen. The surgeon then places small ... that stimulates contraction of the diaphragm muscle which allows the patient to breathe. The ...

Radius Selects First Preclinical Candidate From SARM Discovery Program for the Treatment of Muscle Loss and Other Musculoskeletal Conditions

... therapy for the treatment of age-related muscle loss (sarcopenia) and other musculoskeletal ... of androgens, including testosterone, on muscle and bone while avoiding the unwanted ... anabolic therapies for bone loss and/or muscle wasting caused by aging, burns and trauma, ...

FDA Broadens US Indication for Once-Yearly Reclast(R) as Only Osteoporosis Treatment Approved for Prevention of Fractures After a Hip Fracture

... common side effects are flu-like symptoms, fever, muscle or joint pain and headache. Patients should ... doctor if they develop severe bone, joint or muscle pain, numbness, tingling or muscle spasms. For more information about Reclast, ...

TorreyPines Therapeutics Initiates Clinical Trial to Evaluate Analgesic Effect of Oral Prodrug of Tezampanel

... forms of chronic pain such as neuropathic pain, muscle spasticity and rigidity, thrombosis, ... and disorders such as migraine, chronic pain, muscle spasticity and rigidity, xerostomia and cognitive ... of chronic pain such as neuropathic pain, muscle spasticity and rigidity, thrombosis, epilepsy, ...

European Union's CHMP Issues Positive Opinion on Sugammadex

... for anesthesiologists to maintain optimal muscle relaxation to the end of a surgical procedure and ... president, Schering-Plough Research Institute. muscle relaxants play several critical roles in general ... Reversal agents are given to stop the effects of muscle relaxants, allowing patients to breathe on their ...

AstraZeneca Submits sNDA for SEROQUEL XR(TM) for the Treatment of Generalized Anxiety Disorder - a First for the Atypical Antipsychotic Class of Medicines

... Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status, and evidence ... accompany the anxiety include fatigue, headaches, muscle tension, muscle aches, difficulty swallowing, ...

Patients Treated with Risperidone Long-Acting Injection had a Significantly Longer Time to Relapse Compared to Quetiapine in International Clinical Study

... increased saliva, constipation, fever, tremors, muscle stiffness, abdominal pain, anxiety, ... RLAI were sleepiness, restlessness, tremors and muscle stiffness, stomach upset, constipation, dry ... in pulse, heart rate, or blood pressure; or muscle pain and weakness. Treatment should be stopped if ...

New Data on SEROQUEL XR(TM) in Treatment of Both Major Depressive Disorder and Generalized Anxiety Disorder Presented at APA Annual Meeting

... Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status, and evidence ... accompany the anxiety include fatigue, headaches, muscle tension, muscle aches, difficulty swallowing, ...

Vicus Therapeutics Records Last Patient Visit of Phase 2, VT-122 Trial for the Treatment of Cachexia in Patients With Advanced Lung Cancer

... efficacy endpoints assessed were maintenance of muscle mass (lean body mass) and function (grip ... VT-122 Cachexia is a debilitating, progressive muscle wasting condition manifested by unintentional weight loss, muscle weakness, anemia, fatigue, and death. In advanced ...

PTC Therapeutics Announces Initiation of Phase 2b Registration-Directed Clinical Trial of PTC124 in Duchenne/Becker Muscular Dystrophy

... that is critical to the structural stability of muscle fibers. Patients develop progressive muscle weakness that leads to loss of ambulation, ... Phase 2b study will evaluate activity at home, muscle and heart function, strength, cognitive ...

Study Shows Once-Yearly Reclast Better than Risedronate at Increasing Bone Mass in Patients With Osteoporosis Caused by Glucocorticoids

... post-infusion symptoms such as fever and muscle pain. The majority of these symptoms occurred in ... common side effects are flu-like symptoms, fever, muscle or joint pain and headache. Patients should ... doctor if they develop severe bone, joint or muscle pain, numbness, tingling ...

Most Back Pain Could Be Cured Without Surgery or Drugs if Doctors Treated Muscles - Not the Spine - Says Leading Pain Specialist

... are the primary source of chronic back pain. And muscle pain can almost always be successfully treated ... in Anesthesiology and Psychiatry and Director of muscle Pain Research at the NYU School of Medicine. ... Dr. Kraus developed landmark tests that evaluate muscle strength and flexibility and a series of simple ...

Final Data From the Bioheart Seismic Trial Suggest Safety, Efficacy of Autologous Stem-Cell Therapy for Treating Congestive Heart Failure

... involves a physician removing a small amount of muscle obtained from the patient's thigh. From this muscle specimen, autologous myoblasts (muscle stem ... vascular surgeon. The myoblast-based muscle formation in the newly populated regions of scar ...
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(Date:8/27/2014)... may not be getting effective doses of the HIV ... The initial dosing studies, completed before the drug was ... a protein that is key to removing maraviroc from ... maximum levels of the protein including nearly half ... their bodies compared to those who lack the protein ...
(Date:8/27/2014)... manipulating neural circuits in the brain of mice, ... memories. The research, led by Howard Hughes Medical ... of Technology (MIT), reveals that the connections between ... information about an experience and the part of ... that experience are malleable. , Altering those ...
(Date:8/27/2014)... listen carefully to someone, the first thing we do ... stop moving altogether. This strategy helps us hear better ... , This interplay between movement and hearing also has ... has long suggested that the brain,s motor cortex, which ... rise to our conscious perception of sound. , A ...
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(Date:8/28/2014)... be given to healthy volunteers in the UK, The ... of an series of safety trials of potential vaccines ... than 1,400 people in the current outbreak in West ... co-developed by the US National Institutes of Health (NIH) ... an international consortium in response to the Ebola epidemic, ...
(Date:8/28/2014)... Catalent Pharma Solutions, the leading global ... for drugs, biologics and consumer health products, today ... Services, and Chris Greco, Manager, Comparator and Ancillary ... Active Control Clinical Trials” at the forthcoming US ... the 9th – 10th September, 2014 in Philadelphia, ...
(Date:8/28/2014)... vaccine to prevent Ebola virus disease will begin next ... Diseases (NIAID), part of the National Institutes of Health. ... of a vaccine co-developed by NIAID and GlaxoSmithKline (GSK) ... to generate an immune system response in healthy adults. ... in Bethesda, Maryland. , The study is the first ...
(Date:8/28/2014)... A subset of patients with stage III colon ... therapy, according to a new study in ... the American Gastroenterological Association. , When added to the ... irinotecan therapy improved overall survival rates for patients with ... in about 10 to 20 percent of colorectal cancers. ...
(Date:8/28/2014)... over who identify themselves as ,old, feel worse about ... have lower value than younger age groups. , New ... ,Being old and ill, across different countries: social status, ... from the European Social Survey. Respondents, who were all ... health., The researchers found that those living in societies ...
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