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Motor in Medical Technology

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

... be considered. Potential for Cognitive and motor Impairment: RISPERDAL(R) CONSTA(R) has the potential to impair judgment, thinking, or motor skills. Patients should be cautioned about operating hazardous machinery, including motor vehicles, until they are reasonably certain that ...

Neuralstem's Human Stem Cells Integrate into Nervous System of Rats with Animal Model of ALS

... Make Synaptic Contact with Host motor Neurons ROCKVILLE, Md., March 9 ... US: CUR) made synaptic contacts with the motor neurons of rats with ALS-like symptoms, a paper ... mature structural connections, with the rat motor neurons, something which has not been ...

Merck Serono's Safinamide Significantly Improved Motor Function in Patients With Advanced Parkinson's Disease in a Phase III Pivotal Trial

... to late-stage Parkinson's disease patients with motor fluctuations by 1.3 hours. "ON" time represents ... patients experience their best level of motor functioning. The two safinamide treatment ... Parkinson's disease, increases daily "ON" time of motor functioning," said Dr. Bernhard Kirschbaum, Merck ...

Kyowa Hakko Kirin Announces Development Policy for Anti-Parkinson's Disease Drug KW-6002 (Istradefylline)

... who were experiencing wearing-off phenomenon*, a motor complication, while receiving Levodopa therapy ... disorder which is characterized by motor symptoms such as slowness of movement, rigidity, ... in the brain which is thought to cause the motor symptoms. The symptoms of Parkinson's disease are ...

Schering-Plough Reports Preladenant Meets Primary Endpoint in Phase II Dose-Finding Trial for Parkinson's Disease

... to severe Parkinson's disease experiencing motor fluctuations and abnormal involuntary movements ... with moderate to severe Parkinson's disease with motor fluctuations and dyskinesias. All patients were ... and/or entacapone, but were still experiencing motor fluctuations and dyskinesias. The previous ...

New Evidence That Brain-Plasticity Based Training has Broad Impact: Improved Cognition in Boomers, Improved Motor Control in Older Adults

... with aging. As people age, they have less motor control partly because of changes in ... indicating that the age-related decline in motor control can be renormalized to that of younger ... custom computer-based training program to improve motor control of the hand. It required the user to ...

Sangamo BioSciences Initiates Phase 2 Clinical Trial of Treatment for Amyotrophic Lateral Sclerosis (ALS)

... blood vessel and muscle growth. In ALS, the motor nerves comprised of nerve cells in the brain ... nerve damage reveal positive effects of SB-509 on motor nerve function and muscle composition. Similar effects on motor nerves and muscles in these patients may slow the ...

Sangamo BioSciences Announces Presentation of Phase 1b ZFP Therapeutic Data at American Diabetes Association Meeting

... an applied electrical signal, in both sensory and motor nerves. Specifically, improvement in neurologic ... conduction velocity (NCV) in both sensory and motor nerves is a method of assessing the integrity or ... with DN over time. NIS-LL includes measures of motor and sensory nerve heath as well as reflex testing ...

Sangamo BioSciences Provides Update on Diabetic Neuropathy Clinical Programs

... moderate to severe diabetic peripheral sensory motor neuropathy (DN). The study is designed to ... SB-509 has proven effective in protecting motor and sensory nerve function from disease-induced ... This gradually evolves to loss of sensation and motor function as nerve damage progresses. Ulcers ...

Alseres Pharmaceuticals Announces 12 Month Interim Results from the Phase I/IIa Cethrin(R) Clinical Trial in Acute Spinal Cord Injury

... being investigated for its potential to restore motor and sensory function after spinal cord injury, or ... injury patients showed marked recovery of motor and sensory function after treatment as ... 7) showing the same 2-grade or better recovery of motor and sensory function. (Logo: ...

Intra-Cellular Therapies Presents Data on Its Schizophrenia and Cognition in Schizophrenia Programs at the 14th Biennial Winter Workshop on Schizophrenia and Bipolar Disorders

... high levels of dopamine antagonism that cause motor disturbances and other deleterious side effects. ... ITI-002 also may be useful in treating the motor deficits that are associated with Parkinson's ... side effects, including troublesome actions on motor function, weight gain, and metabolic ...

Insmed Provides Update on IPLEX(TM) Expanded Access Program in Italy for the Treatment of Amyotrophic Lateral Sclerosis

... affects nerve cells in the brain and spinal cord. motor neurons reach from the brain to the spinal cord ... the body. The progressive degeneration of the motor neurons in ALS eventually leads to their death. When the motor neurons die, the ability of the brain to initiate ...

Alseres Pharmaceuticals Concludes Enrollment in the Cethrin(R) Phase I/IIa Clinical Trial in Acute Spinal Cord Injury

... A being complete impairment with no sensory or motor function below the site of injury and E being ... Grades B through E designate increasing levels of motor and sensory function. The subjects in the Cethrin ... the hallmark of which is recovery of some motor function. In subjects with cervical injuries, the ...

Ceregene Presents Long-term Follow-up From Phase 1 Trial of CERE-120 in Parkinson's Disease

... Data Suggest Continued Improvement in motor Function at 24 Months SAN DIEGO, Dec. 12 ... that the statistically significant improvement in motor symptoms seen in the Parkinson's patients 12 ... disease and are responsible for the major motor impairments. CERE-120 is delivered ...

Sangamo BioSciences Announces Completion of Enrollment of Phase 2 Clinical Trial of ZFP Therapeutic for Diabetic Neuropathy

... (QST), clinically relevant improvements in motor and sensory nerve conduction velocities (NCV) and ... with mild to moderate diabetic peripheral sensory motor neuropathy in the legs. A total of 102 subjects ... This gradually evolves to loss of sensation and motor function as nerve damage progresses. Ulcers ...

PET Scans Show Gene Therapy Normalizes Brain Function in Parkinson's Patients

... the activity in a key node of the Parkinson's motor network. The investigators were not expecting to ... and then again one year after the surgery. The motor network on the untreated side of the body got ... side got better. The level of improvements in the motor network correlated with increased clinical ...

Tezampanel, TorreyPines Therapeutics' Lead Compound, Reduced Muscle Spasticity and Rigidity in Preclinical Study Conducted at University of California, San Diego

... Data Suggest Potential for Treating motor System Disorders LA JOLLA, Calif., Oct. 17 ... sclerosis, cerebral palsy and other progressive motor system disorders caused by brain trauma or spinal ... paraplegic rats. In humans with motor system disorders, muscle spasticity and rigidity, ...

Neupro(R) (Rotigotine Transdermal System) Effective in Controlling Early Morning Motor Impairment and Generally Well-Tolerated for Long-Term Use in Patients with Parkinson's Disease

... patch, is effective in controlling early morning motor impairment, provides improvement in ... the efficacy of Neupro(R) on early morning motor impairment and sleep disorders. Fifty-four ... considerable improvement in early morning motor function sufficient to meet response criteria ...

Families of Spinal Muscular Atrophy Announces Latest Developments on Three SMA Drug Discovery Programs

... Tetracyclines at Paratek Pharmaceuticals to correct gene splicing; and 3) motor neuron replacement program at California Stem Cell and UCI. These three ... in the path towards human clinical trials of the drug candidate." motor Neuron Replacement Program: California Stem Cell (CSC) is preparing for ...

Terumo Heart, Inc. Reaches Clinical Milestone as the 100th Patient Worldwide Receives the DuraHeart(TM) Left Ventricular Assist System

... within the blood chamber. Permanent magnets couple the impeller to the motor so when the motor spins, it causes the impeller to rotate and pump blood from the heart to ...

New Studies on Once-Daily Extended Release Pramipexole Presented at American Academy of Neurology Annual Meeting

... II relates to activities of daily living and UPDRS Part III relates to motor symptoms. The UPDRS II+ III score ranges from 0 (no disability) to 160 ... warning signs during activities of daily living, including operation of a motor vehicle, which sometimes resulted in accidents. Hallucinations and ...

Study Data Show Positive European Experience With DuraHeart Left Ventricular Assist Device for Advanced Stage Heart Failure Patients

... within the blood chamber. Permanent magnets couple the impeller to the motor so when the motor spins, it causes the impeller to rotate and pump blood from the heart to ...

David Feldman, M.D. Appointed Co-Principal Investigator of DuraHeart(TM) Left Ventricular Assist System U.S. Clinical Trial

... and sensors to keep it centered within the blood chamber. Magnets in the motor couple to the impeller so that when the motor spins, it causes the impeller to rotate and pump blood from the heart to ...

Terumo Heart, Inc. Reports Clinical Progress in the DuraHeart(TM) U.S. Pivotal Trial as NewYork-Presbyterian Hospital/Columbia University Medical Center Implants First Patient

... within the blood chamber. Permanent magnets couple the impeller to the motor so when the motor spins, it causes the impeller to rotate and pump blood from the heart to ...

Archimedes Pharma Announces Successful Proof-of-Concept Results on Two Intranasal Development Projects

... 26 /PRNewswire/ -- - Intranasal Apomorphine for the Treatment of motor Fluctuations in Advanced Parkinson's Disease - Intranasal Diazepam ... in high value markets. The agents are being developed for the treatment of motor fluctuations or "off episodes" in Parkinson's disease and Acute Repetitive ...

Endo Pharmaceuticals Announces Research Collaborations to Develop Novel Pain Treatments and Discover Potential Cancer Treatments

... of Neurobiology, that targets pain-sensing neurons without affecting motor neurons. Under the terms of the agreement, Endo will receive exclusive ... at Harvard to explore the potential to block pain without affecting motor or other functions, and with the team at Aurigene to discover new oncology ...

VA-NIH Study Offers Hope for Parkinson's Patients

... Patients who received DBS gained an average of 4.6 hours per day of good motor control and few or no involuntary movements, compared with no gain for ... alone; 71 percent of DBS patients showed significant gains in motor function, compared with only 32 percent of drug therapy patients; and ...

Pregnant Women Need Omega-3 to Boost Infant Development

... the last months of pregnancy boosts an infant's sensory, cognitive, and motor development. The research team reached its conclusion by first measuring ... the researchers discovered visual acuity, cognitive development, and motor development were closely linked to DHA concentration in the umbilical cord ...

Genzyme Genetics Announces Launch of Carrier Testing and Prenatal Diagnosis for Spinal Muscular Atrophy

... motor Neuron Disease is Leading Cause of Death for Infants WESTBOROUGH, Mass., ... fetuses. SMA is characterized by progressive muscle degeneration of motor neurons, resulting in severe muscle weakness. In 60-70 percent of cases, ...

New Michael J. Fox Foundation Initiative Will Drive Development of Web-Based Tools to Increase Patient Participation in Parkinson's Clinical Trials

... and takes an incredible toll on people with PD, where unpredictable motor and non-motor effects, as well as the efficacy and side effects of ... up to $1 million in funding for Web-based clinical assessments of various motor and/or non-motor symptoms of PD for up to two years. Pre-proposals will be ...

FDA Approves XYZAL(R) (levocetirizine dihydrochloride) Oral Solution for the Relief of Seasonal and Year Round Allergies and Chronic Idiopathic Urticaria

... engaging in hazardous occupations requiring complete mental alertness and motor coordination, such as operating machinery or driving a motor vehicle, after ingestion of XYZAL(R). Concurrent use of XYZAL(R) with ...

Intra-Cellular Therapies Presents Preclinical Data From Schizophrenia and Sleep Maintenance Programs

... symptoms without incurring high levels of dopamine antagonism that cause motor disturbances and other deleterious side effects. In addition, the wide ... but they also have limiting side effects, including troublesome actions on motor function, weight gain, and metabolic symptoms (diabetes and ...

Five Clinical Studies to Receive $2.5 Million Under Foundation's 2007 Clinical Discovery Program

... and intestine, causes disturbances in levodopa absorption that result in motor fluctuations. Dr. Bronstein will test the frequency of the bacterial infection in PD patients with motor fluctuations and enroll those who test positive for the bacterium in a ...

Immunosyn Corporation Releases SF-1019 Study Results

... improvements within 10-20 minutes were apparent in tremor, numbness, motor strength, walking, balance, speech, pain and coordination. Within 24 hours ... continued with each subsequent weekly injection there was an increase in motor strength, lessening of fatigue, walking, alleviation of numbness and ...

Survival Data for Avicena's Amyotrophic Lateral Sclerosis Drug Candidate, AL-02, to be Presented at 18th International Symposium on ALS/MND

... ABOUT ALS ALS is a neurodegenerative disease that attacks the motor neurons of the brain and spinal cord that are responsible for voluntary muscle movement. As these motor neurons degenerate, their ability to send impulses to the muscle fibers is ...

Video: New Research Discovers Independent Brain Networks Control Human Walking

... Krieger Institute Study Enhances Understanding of Brain Plasticity and motor Skills, Signaling Advancements for Future Rehab Practices BALTIMORE, ... more about the way the brain learns, relearns and adapts in relation to motor skills, physical therapy professionals have a vastly expanding toolbox ...

Sixty-One Percent of Newly Diagnosed Parkinson's Disease Patients Do Not Receive Any Drug Treatment in the First Year of Diagnosis

... specifically motor response complications. Levodopa provides greater motor benefit than dopamine agonists, such as GlaxoSmithKline's Requip or ... of levopoda-induced side effects, including dyskinesias, off time (sudden motor switches between normal and Parkinson movements) and wearing-off ...

FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications

... or those predisposed to hypotension. Other potentially serious adverse events include seizures, elevated prolactin levels, cognitive and motor impairment, body temperature elevation, and trouble swallowing. The most common treatment-emergent adverse event associated with Zyprexa use in ...

AIMSPRO is Awarded TGA Orphan Status for the Treatment of Amyotrophic Lateral Sclerosis

... agent AIMSPRO(R) has been awarded Orphan Status for the treatment of Amyotrophic Lateral Sclerosis (ALS). ALS is the most common form of motor Neuron Disease (MND), also known as Lou Gehrig's disease. AIMSPRO has already achieved TGA Orphan Status for the treatment of Krabbe Leukodystrophy ...

Autism Studies Presented at Mid-Atlantic Research Consortium Meeting

... in humans. By altering the flow of serotonin, a neurotransmitter in the brain, Blue showed that mice behaved less socially, had impairments in fine motor functions and increased repetitive behaviors. The changed animal behaviors, said Blue, shared similarities with some behaviors seen in children with ...
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(Date:10/29/2014)... As bodies decompose, their types and numbers of ... provide could mean the difference between a closed ... University is using a more than $866,000 U.S. ... investigators examine these changing populations. The microbial communities ... of death, gender, race, socioeconomic relations and more, ...
(Date:10/29/2014)... — Cambridge, MA and Hebei, China — BGI Tech ... quality sequencing of the Jujube genome. Jujube is the ... the Jujube genome is particularly difficult to sequence due ... It is the first time that a genome in ... has been recently published in Nature Communications ...
(Date:10/29/2014)... kidney cancer patients in Europe sheds light on the ... apparent link between exposure to aristolochic acid and incidence ... by an international team led by scientists from the ... underscores the importance of investigating possible sources of exposure ... the Aristolochia genus, also has been suspected of causing ...
Breaking Biology News(10 mins):MSU partners with Detroit to investigate death scenes 2BGI Tech and Hebei Agricultural University complete the genome sequencing of the jujube tree 2Study sheds light on genetic architecture of kidney cancer 2Study sheds light on genetic architecture of kidney cancer 3
(Date:10/30/2014)... model developed by NIH grantees predicts that women must ... infection via vaginal sex, whereas just two doses per ... sex. This finding helps explain why two large clinical ... failed to show efficacy. Participants in the VOICE ... tenofovir (another antiretroviral) for HIV prevention were counseled to ...
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