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Marrow in Medical Technology

British Woman Celebrates a Year of Living Cancer-Free

... treatments, including chemotherapy and a bone marrow transplant, failed to keep her in remission. Ms. ... multiplied. Within a month, a study of her bone marrow -- the site affected by the type of leukemia she ... abnormal white blood cells accumulate in the bone marrow and impede the production of normal blood cells. ...

UPCI Joins ExCell Research Study Using Stem Cells for Leukemia and Lymphoma Patients

... stem cells, as an alternative treatment to bone marrow transplants for hematological malignancies, ... blood stem cells instead of a traditional bone marrow transplant opens tremendous ... diseases like leukemia and lymphoma." Bone marrow transplantation is a life-saving treatment for ...

Bayer Announces Leukine(R) Data Presentations at 45th American Society of Clinical Oncology (ASCO) Annual Meeting

... following allogeneic and autologous bone marrow transplantation (BMT), peripheral blood stem cell ... patients undergoing PBSC transplantation and bone marrow transplantation failure or engraftment delay. ... patients with excessive leukemic blasts in bone marrow or peripheral blood (10 percent), in patients ...

Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support

... mediate the cells' ability to home to the bone marrow and eventually repopulate the patient's blood and ... with HSCs from any source, including from bone marrow and peripheral blood. FT1050 was discovered by ... of HSCs is necessary to restore normal bone marrow function. Also the immune cells generated by the ...

Cardium Reports on Applicability of Corgentin to Stem Cell Therapies: Independent Studies Indicate that Ad5IGF-1 Potentiates Stem Cells to Improve Cardiac Function After Heart Attack

... Mesenchymal Stem Cells Accelerate Bone marrow Stem Cell Mobilization via Paracrine Activation ... to massive stem cell mobilization from the bone marrow and their increased homing in the injured heart ... receptor 4 (found on these stem cells in the bone marrow but reduced after ex vivo expansion) with the ...

ViroPharma Announces Discontinuation of Maribavir Phase 3 Study in Liver Transplant Patients

... current therapies, including suppression of bone marrow function. About maribavir Maribavir is a ... or myelosuppression (a condition in which bone marrow activity is decreased, resulting in fewer red ... use is limited by toxicities, most notably bone marrow suppression and renal impairment. About ...

Nplate(R) Approved in the European Union for the Treatment of Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

... muscle spasms, nausea, contusion, diarrhoea, bone marrow disorder, influenza like illness, insomnia and ... after cessation of treatment and increased bone marrow reticulin have been associated with romiplostim ... with Nplate in clinical studies were bone marrow reticulin deposition and worsening ...

ThermoGenesis Announces MXP Involvement in New Regenerative Medicine Initiatives

... PROGRAMS INCLUDE BONE marrow CLINICAL TRIAL IN ITALY RANCHO CORDOVA, ... of Naples in Italy to study the effect of bone marrow derived mononuclear cells on patients with ... patients with mononuclear cells derived from bone marrow for several years. The early results from his ...

Dacogen(R) (decitabine for injection) Data Presented on a Phase II Clinical Trial in Elderly Patients with Acute Myeloid Leukemia (AML)

... no evidence of disease outside of the bone marrow and absolute neutrophil and platelet counts of ... had intermediate or poor risk cytogenetics (bone marrow tests to identify abnormal chromosomes), which ... rapidly progressing cancer of the blood and bone marrow characterized by an overgrowth of abnormal blood ...

Long-term Follow Up Interim Data Show Nplate(TM) Increased and Sustained Platelet Counts in Adult Chronic ITP Patients

... treatment due to AEs. Bone marrow reticulin was present or increased in eight ... blood count that occurs secondary to bone marrow suppression, in MDS patients receiving ... treatment for MDS, with the exception of bone marrow transplantation, and roughly 70 percent of all ...

Alexion Reports Positive Results from AEGIS Registration Study of Soliris in Japanese Patients With PNH

... immunosuppressive therapy and, infrequently, bone marrow transplantations -- a procedure that carries ... hemoglobinuria-type cells in bone marrow failure syndrome. Blood. 2002;100 ... EM, et al. Relationship between bone marrow failure syndromes and the presence of ...

Kiadis Pharma Receives Two Orphan Drug Designations for Reviroc(TM) From the FDA

... cancer cells from an autologous graft in bone marrow transplantations for end-stage blood cancer ... autologous transplant uses the patient's own bone marrow to serve as a graft. Bone marrow transplants are broadly recognized as a ...

Research Explores the Effects of Stem Cell Source and Patient Age on Stem Cell Transplantation Outcomes

... The transplanted stem cells travel to the bone marrow and begin to produce new blood cells, replacing ... were a suitable alternative to mismatched bone marrow or peripheral blood transplants because cord ... For successful transplantation, bone marrow and peripheral blood donors are examined for ...

GSK Reports PROMACTA(R) (eltrombopag) Significantly Increased Platelet Counts and Reduced Bleeding in Long-Term Study of Patients With Chronic ITP

... or laboratory symptoms suggestive of bone marrow fibrosis in patients taking PROMACTA. ... and differentiation of megakaryocytes, the bone marrow cells that give rise to blood platelets. ... disease and monitor closely. Bone marrow Reticulin Formation and Risk for ...

Kiadis Pharma Announces Positive Clinical Results for ATIR(TM) in Mismatched Bone Marrow Transplantations

... immune reconstitution following a mismatched bone marrow transplantation. Nineteen end stage blood ... no matching donor is available. "Bone marrow transplantations are often the only treatment ... safe and potentially life-saving mismatched bone marrow transplantation as a treatment option for ...

Nplate(TM) (Romiplostim) Receives Positive Opinion for Marketing Authorisation in the European Union

... is necessary for growth and maturation of bone marrow cells that produce platelets. The CHMP ... spasms, nausea, contusion, diarrhea, bone marrow disorder, influenza like illness, insomnia and ... after cessation of treatment and increased bone marrow reticulin have been associated with ...

FDA Approves Promacta(R) (Eltrombopag), the First Oral Medication to Increase Platelet Production for People With Serious Blood Disorder

... and differentiation of megakaryocytes, the bone marrow cells that give rise to blood platelets. PROMACTA ... disease and monitor closely. Bone marrow Reticulin Formation and Risk for Bone marrow Fibrosis: PROMACTA is a thrombopoietin (TPO) ...

StemCor Systems Receives CE Mark for MarrowMiner(TM) System for Bone Marrow Collection

... next-generation technology for use in bone marrow transplants, for accelerating bone healing in ... to physicians outside of the US, whereby bone marrow can be harvested in a more facile and relatively ... is designed to rapidly and easily harvest bone marrow in a minimally invasive manner, in the ...

Protein Key to Control Growth of Blood Cells

... --Findings May Aid in Bone marrow Transplants, Blood Diseases-- PHILADELPHIA, ... The findings may help improve the success of bone marrow transplants and develop better treatments for ... to manipulate HSCs for more effective bone marrow transplants for cancer patients after high ...

Eisai Provides Preliminary Efficacy Update On EORTC Phase III Trial of Dacogen(R) Versus Supportive Care in Patients With Myelodysplastic Syndromes

... is a potentially life-threatening group of bone marrow diseases that limit the production of functional ... in the study, patients had to have bone marrow blast counts between 11 and 30 percent. Patients ... patients with high-risk MDS may experience bone marrow failure, which may lead to death from bleeding ...

SuperGen Comments on Preliminary Efficacy Update on EORTC Phase 3 Trial of Dacogen(R) Versus Supportive Care in Patients With Myelodysplastic Syndromes

... in the study, patients had to have bone marrow blast counts between 11 and 30 percent. Patients ... Myelodysplastic syndromes, or MDS, is a bone marrow disorder characterized by the production of ... patients with high-risk MDS may experience bone marrow failure, which may lead to death from bleeding ...

Soliris(R) Improved Fatigue Independent of Changes in Anemia in Patients with PNH by Controlling Hemolysis

... therapy and, infrequently, bone marrow transplantations -- a procedure that carries ... nocturnal hemoglobinuria-type cells in bone marrow failure syndrome. Blood. 2002;100 ... H, Dunn D, Young NS. Relationship between bone marrow failure syndromes and the presence of ...

Cardiogenesis Announces Preliminary Clinical Results With the PHOENIX System Combining TMR + Stem Cells

... revascularization (TMR) with autologous bone marrow derived stem cells. The presentation titled ... the application of TMR in combination with bone marrow derived stem cells in targeted ischemic heart ... when delivering concentrated bone marrow derived stem cells to the stimulated tissue ...

Kiadis Pharma Announces Collaboration With the Julius Maximilians University of Wurzburg, Germany

... GvHD is a major complication of allogeneic bone marrow transplantations. By preventing the occurrence of ... it could improve the general outcome of bone marrow transplants. About Kiadis Pharma Kiadis ... on complications and limitations of bone marrow transplantations in blood cancer patients. The ...

Alexion Completes Enrollment in AEGIS Registration Study of Soliris(R) (eculizumab) in Patients with PNH in Japan

... therapy and, infrequently, bone marrow transplantations -- a procedure that carries ... nocturnal hemoglobinuria-type cells in bone marrow failure syndrome. Blood. 2002;100 (12):3897-3902. ... Sloand EM, et al. Relationship between bone marrow failure syndromes and the presence of ...

Genzyme Announces Presentation of New Positive Data on Carticel(R)

... that compared the results of ACI following a marrow stimulation technique versus no significant ... They concluded that patients who had a previous marrow stimulation technique and were ... to fail than patients who had not undergone a marrow stimulation technique prior to treatment with ....

NeoStem Reports Positive Stem Cell Industry Research Trends From The Journal of the American Medical Association and Third Annual Stem Cell Summit

... that stem cells harvested from blood or bone marrow did appear to provide disease-ameliorating ... care in treating over 40 diseases including bone marrow cancers and other diseases such as radiation sickness or bone marrow deficiencies from chemotherapy. At the recent ...

A Functional Immune System Can Be Derived From Embryonic Stem Cells, Preliminary Study Finds

... cells as an alternative source of cells for bone marrow transplantation. This hopeful news for patients ... could then be transplanted into mice whose own marrow had been destroyed by radiation, rescuing their marrow function and beginning to produce necessary blood ...

Northwestern Memorial Transplant Program Initiates New Study

... transplant stem cells from a kidney donor's bone marrow into the recipient, with the hope of gradually ... does it work? Stem cells are formed at the marrow and are common blood cells from which other ... After the kidney is removed, bone marrow is drawn from the donor's hip bone. About three ...

Alexion Commences Dosing in AEGIS Registration Study of Soliris(R) (eculizumab) in Patients with PNH in Japan

... therapy and, infrequently, bone marrow transplantations -- a procedure that carries ... nocturnal hemoglobinuria-type cells in bone marrow failure syndrome. Blood 2002;100:3897-3902. ... Maciejewski, et al. Relationship between bone marrow failure syndromes and the presence of ...

PNH Patients With Lower Levels of Hemolysis, Mild Anemia and Minimal Transfusion Support Have Significant Disease Burden; Soliris(R) Therapy Provided Clinical Improvements in PNH Patients Regardless of Disease Severity

... In addition, in patients with history of bone marrow failure, units transfused were reduced from mean ... therapy and, infrequently, bone marrow transplantations -- a procedure that carries ... nocturnal hemoglobinuria-type cells in bone marrow failure syndrome. Blood 2002;100:3897-3902. ...

Long-Term Soliris(R) Therapy Improved or Stabilized Kidney Function in Patients With PNH

... Socie, M.D., Ph.D., Head, Department of Bone marrow Transplant, St. Louis Hospital, Paris. "In our ... therapy and, infrequently, bone marrow transplantations - a procedure that carries ... nocturnal hemoglobinuria-type cells in bone marrow failure syndrome. Blood 2002;100:3897-3902. ...

Soliris(R) Demonstrates Reductions in Hemolysis and Improvements in Fatigue, Overall Quality of Life and Anemia in a Broad Population of PNH Patients

... immunosuppressive therapy and, infrequently, bone marrow transplantation -- a procedure that carries ... nocturnal hemoglobinuria-type cells in bone marrow failure syndrome. Blood 2002;100:3897-3902. (9) ... Maciejewski, et al. Relationship between bone marrow failure syndromes and the presence of ...

Kiadis Pharma Announces Promising Phase II Clinical Trial Results for Reviroc

... cancer cells from an autologous graft in bone marrow transplantations for end-stage blood ... autologous transplant uses the patient's own bone marrow to serve as a graft. Bone marrow transplantations are broadly recognized as a ...

PNH Patients Treated with Soliris(TM) Experienced Dramatic Reduction in Blood Clots During Clinical Trials

... therapy and, infrequently, bone marrow transplantations -- a procedure that carries ... nocturnal hemoglobinuria-type cells in bone marrow failure syndrome. Blood 2002;100:3897-3902. ... Maciejewski, et al. Relationship between bone marrow failure syndromes and the presence of ...

Three Surgeons in East Texas Are Successfully Integrating a Novel Stem Cell Procedure for Spine Surgeries

... from a patient's own body. During surgeries for the neck and back, bone marrow is extracted from the hip through a small incision. The marrow is processed by an FDA-approved device and the living cells are delivered ...

Cardiogenesis Announces Presentation of its PHOENIX(R) Combination TMR Plus Stem Cell Delivery System at the International Society of Minimally Invasive Cardiothoracic Surgeons (ISMICS) Annual Meeting

... approved. The abstract " One Year Follow up of Combined Autologous Bone marrow Derived Progenitor Cell Therapy and Transmyocardial Laser ... published in the European Journal of Cardiothoracic Surgery, " Bone marrow Laser Revascularisation for Treating Refractory Angina Due to Diffuse ...

Proteolix Presents Positive Clinical Data for Carfilzomib in Multiple Myeloma at the 2009 ASCO Annual Meeting

... by Sundar Jagannath, M.D., Chief of the Multiple Myeloma Program, Bone marrow and Blood Stem Cell Transplantation at St. Vincent's Comprehensive Cancer ... Associate Professor of Medicine, Division of Oncology, Section of Bone marrow Transplantation at Washington University School of Medicine in a poster ...

Muscadine Grape Skin Dietary Supplement Protects against Cancer Therapy Radiation Side Effects

... develop leukemia. This occurs when normal stem cell found in bone marrow mutate and grow into tumors, causing leukemia's or blood cell cancers. A ... was able to measure early gene defects in the stem cells in the bone marrow of irradiated mice. These cell changes precede cancer of the blood cells ...

Three Studies Presented at the American Society of Hematology Annual Meeting Showed Response to Treatment with Campath(R) in Patients with High-Risk CLL

... sweating, abnormal bruising, and decreased appetite and weight loss. Bone marrow infiltration leads to a lack of healthy blood cells, thus leading to ... parts of particular chromosomes. It can be used on regular blood or bone marrow samples and is very accurate, which is why this test is now used in many ...
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