Economy is Driving Many Osteoporotic Women to Retire Later - But Their Ability to Work May Be Undermined by Sub-Optimal Management of Their Disease
... Almost 34 million Americans are estimated to have low
bone mass, placing them at increased risk for ... Bone Health: The State of Osteoporosis and low
Bone Mass in Our Nation is an update to the ... at high risk for developing osteoporosis due to low
bone mass. Prevalence estimates are based on ...
Prospective Clinical Advantages of Trabecular Metal(TM) Technology Highlighted in Comparative Study
... of the Indiana Research Foundation describes the low
stiffness and osteoconductive properties of ... findings confirmed initial assumptions that the low
stiffness properties of this porous metal ... to directly compare bone-remodeling effects of a low
stiffness porous metal construct to more rigid ...
June 2009 Mayo Clinic Women's HealthSource Highlights Summer Skin Problems, Low Vision and Pilates
... Minn. -- Many devices can help people with low
vision -- a permanent partial loss of eyesight ... of Mayo Clinic Women's HealthSource discusses low
vision, what it is, the causes and the ... surgery don't improve vision sufficiently.
vision is not the normal difficulty reading the ...
Relievant Medsystems Announces Completion of $20 Million Financing
... a novel, minimally invasive treatment for chronic low
back pain, reported today that it has completed a ... the launch of our Intracept(TM) System to treat low
back pain," commented Paul Goeld, President and ... effectiveness of our technology."
back pain impacts nearly one-third of the ...
Pixantrone in Combination with Chemotherapy Regimens Produces Overall Response Rates of 58-74% with Complete Remission Rates of 37-57% in Relapsed/Refractory Aggressive or Indolent NHL
... by the authors to underlie the drugs' low
cardiotoxicity profile in preclinical animal ... by the FDA, the failure of pixantrone to have a low
cardiotoxicity profile or to produce low
cardiac toxicity, the failure of pixantrone to ...
Dainippon Sumitomo Pharma Announces Lurasidone Phase III Data in Patients With Schizophrenia
... was well-tolerated and had a relatively low
discontinuation rate. The findings were presented ... showed that lurasidone was well tolerated with a low
propensity for EPS, QTc interval changes and ... noradrenalin alpha(2c) receptors. Lurasidone has low
affinity for histamine H(1), and cholinergic M(1) ...
RAPAFLO(TM) (silodosin) Provides Rapid and Sustained Benign Prostatic Hyperplasia (BPH) Symptom Relief in as Little as Three Days
... of the targeted prostatic muscle tissue, with a low
incidence of vasodilatory and orthostatic ... and placebo-treated patients were similar and low
(2.6% and 1.5%, respectively). In addition, the ... The incidence of treatment-related dizziness was low
and only slightly higher among RAPAFLO(TM) than ...
Three Clinical Presentations on Tapentadol Extended Release Tablets for Chronic Pain Featured at 2009 American Pain Society Annual Meeting
... challenge in the United States, and chronic low
back pain is the most common cause of disability ... release tablets to treat patients with chronic low
back pain, including pivotal Phase 3 safety, ... Efficacy and Safety of Tapentadol ER for Chronic low
Back Pain: Results of a Randomized, Double-blind, ...
Lack of Food Variety Puts Kids With Autism at Risk for Poor Nutrition
... be at risk for nutrition problems. Kids with low
food variety scores who are at risk could then be ... the red blood cells of children with autism have low
levels of a fatty acid linked to cognitive ... report, warrants further research into how the low
fatty acid levels may trigger biochemical changes ...
AstraZeneca Submits NDA for Low Dose Aspirin/Esomeprazole Combination Product
... (FDA) seeking approval for a product combining low
dose aspirin with esomeprazole magnesium for the risk reduction of low
dose aspirin-associated gastric and/or duodenal ... magnesium) for the risk reduction of low
dose aspirin-associated gastric and/or duodenal ...
New Weight Loss Hope for People with Diabetes
... loss with exercise. NutriSystem D is based on a low
Glycemic Index diet that integrates good carbohydrates into its meal plan. It's also low
in fat and high in fiber. The Glycemic Index ... that emphasize healthful whole grains, as well as low
Newly Published Phase III Study Shows Arzoxifene Significantly Increased Bone Mineral Density
... (BMD) in postmenopausal women with normal or low
bone mass, versus placebo.
In addition, ... in postmenopausal women with osteoporosis or low
These data are from the ... in postmenopausal women with osteoporosis or with low
bone density. Results from that trial are ...
CRESTOR(R) Reduced CV Risk in Patients Achieving Low LDL and hsCRP Targets in New JUPITER Analysis
... of the JUPITER study show that patients with low
cholesterol levels and elevated high ... patients treated with
rosuvastatin who achieved low
levels of LDL-C and hsCRP had a greater
reduction ... major cardiovascular
events in patients with low
to normal LDL-C but at increased ...
CRESTOR(R) Reduced Risk of Blood Clots in the Veins
... compared to
placebo among men and women with low
to normal cholesterol levels and ... major cardiovascular events in patients with low
normal LDL-C but at increased cardiovascular ... one other risk factor including hypertension, low
history of premature coronary heart ...
SYNTAX Analysis Finds Treatment With TAXUS(R) Express2(TM) Stents More Cost Effective Than Bypass Surgery in Many Patients With Complex Coronary Artery Disease
... more cost effective than CABG in patients with low
or moderate coronary lesion complexity. CABG was ... outcomes between PCI and CABG in patients with low
or moderate lesion complexity," said Keith D. ... for both PCI and CABG. In those patients with low
or moderate lesion complexity, PCI was favored, ...
Worldwide Cost Estimate for Alzheimer's and Dementia Is US$315.4 Billion
... to 3,000 people over 65 years old in each of nine low
and middle income countries (China, India, ... the prevalence of dementia in regions with low
awareness of this emerging public health ... lack of education, lack of exercise, depression, low
birth weight for gestational age, and smaller ...
Alimera Reports Favorable Safety and Efficacy Results From the 12-Month Interim Readout of the Human PK Iluvien(TM) Study
... were enrolled in the PK Study, 20 patients on the low
dose of Iluvien (an approximate 0.23 micrograms ... to intraocular pressure (IOP) were seen in low
dose patients, and 23.5 percent of the high dose ... or greater over baseline and 23.1 percent of the low
dose patients had an improvement in BCVA of 15 ...
Diabetes Patients with High Triglycerides and Low HDL Cholesterol Get the Most Benefit From Fenofibrate Treatment: New Data From the FIELD Study
... triglyceride (2.3
mmol/L-200mg/dL or higher) and low
high-density lipoprotein (HDL) ... an
abnormal combination of high triglycerides and low
HDL cholesterol. Population
studies have shown ... lower triglyceride, and 40% higher in those with low
(<0.96 mmol/L-37mg/dL) than in ...
Nplate(R) Approved in the European Union for the Treatment of Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
... is a serious autoimmune disorder characterised by low
platelet counts in the blood (thrombocytopenia), ... are destroyed by the patient's own immune system. low
platelet counts leave adult ITP patients open to ... processes in ITP are unable to compensate for low
levels of platelets in the blood. Increasing the ...
Medgenics Announces Positive Data From Phase I/II Clinical Trial of EPODURE Treatment of Anemia in Chronic Kidney Disease
... Review Board confirms safety and efficacy of low
approves continuation of trial ... of EPODURE, producing and delivering the low
dose of 18-25 IU/kg/day of the protein ... up to several times per week, and the comparable low
dose does not result in sufficient hemoglobin ...
Intra-Cellular Therapies Announces Successful Outcome of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia
... (DPPM) for the treatment of schizophrenia. A low
dose formulation of ITI-007 (formerly referred to ... available drug candidate being evaluated at low
doses in patients with SMI. An interim analysis ... ITI-007 to potently antagonize 5HT2A receptors at low
ESBATech's Antibody Fragment Enters Phase I/IIa Clinical Development in Osteoarthritis with the Potential for Disease-Modifying Activity
... half life, systemic exposure of ESBA105 is very low
as compared to traditional TNF alpha inhibitors. ... the targeted sites, in combination with extremely low
systemic load, in order to achieve low
risk of systemic drug reactions using topical and ...
Three Clinical Studies of bioTheranostics Molecular Breast Cancer Diagnostics Presented at San Antonio Breast Cancer Symposium
... DX Recurrence Score (RS) of high, intermediate or low
previously reported. The study found that ... an
intermediate Oncotype DX recurrence score into low
and high risk groups.
"We know the best ... tumors. Patients whose tumors expressed no or low
HOXB13 had a clear benefit from ...
Agendia's Breast Cancer Test MammaPrint(R) Identifies New Subset of Low Risk HER2+ Patients
... substantial group of traditionally miscategorized low
patients. Agendia's highly accurate ... high risk, yet MammaPrint was
able to identify a low
risk subgroup of HER2+ patients, who ... HER2/NEU positive
patients, MammaPrint(R) low
risk patients had no relapse.
The results ...
Long-term Follow Up Interim Data Show Nplate(TM) Increased and Sustained Platelet Counts in Adult Chronic ITP Patients
... are destroyed by the patient's own immune system. low
counts leave adult ITP patients open to ... in ITP are also unable to compensate for low
platelets in the blood. Increasing the ... ITP, the incidence of hematologic
malignancy was low
and similar between Nplate and placebo.
Novel Therapeutic Approaches May Transform Treatment and Improve Patient Outcomes in Several Platelet Disorders
... a group of bleeding disorders characterized by a low
number of platelets in the blood, will be ... are typically classified by one of three causes: low
production of platelets in the bone marrow, ... can be safely and effectively transfused with a low
dose of platelets, a strategy that can reduce ...
Lilly Withdraws Application for Additional U.S. Indication for Cymbalta(R) for Chronic Pain
... didn't meet its primary endpoint -- in
back pain. In discussions between Lilly and the ... V. et al. Efficacy of Duloxetine in Chronic low
Pain. Poster presented at the ... Placebo in the Treatment
of Chronic low
Back Pain. Poster presented at the 12th World
Nplate(TM) (Romiplostim) Receives Positive Opinion for Marketing Authorisation in the European Union
... destroyed by the patient's own immune system. low
counts leave adult ITP patients open to ... processes in ITP are unable to compensate for low
platelets in the blood. Increasing the rate of platelet production may
platelet levels associated with ITP.
Seniors Can Be Heartened by New Study on Statins
... week, found the
benefits even for people with low
cholesterol and no major risk for heart
... this study, even people who believe they are at low
a heart attack could benefit from taking ... "This study shows that even if you have low
cholesterol levels, you
aren't safe from heart ...
New Analysis Shows Troubling Trend in Triglyceride Levels May Be Linked to Rising Rates of Obesity
... heart disease.
Other studies have shown that low
HDL is predictive of cardiovascular
events even ... with a combination of high triglycerides and low
levels of HDL
doubled from two to four percent, ... 8.5 to 23 hours.
High triglycerides and LDL and low
HDL levels were characterized in the
analysis as ...
U.S. Navy and U.S. Army to Develop Dengue DNA Vaccine Formulated With Vical's Vaxfectin(R) Adjuvant
... was safe and well-tolerated at both the
1 mg low
dose and 5 mg high dose tested, but even at the high dose induced
levels of neutralizing antibody titers in less ... extensive bleeding,
and shock caused by extremely low
blood pressure. Dengue shock syndrome
most often ...
CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years
... of Colorado School of Medicine.
CIMZIA had a low
occurrence of treatment discontinuation due to ... the two main phase III trials showed there was a low
injection site burning and stinging (n=<3 new cases /100 patient-years) and
level of discontinuations due to adverse events ...
Whatcom County, Washington Participating in NIH Study of Cardiac Arrest Resuscitation Techniques
... advances study Study needed because of low
cardiac arrest survival rates
MINNEAPOLIS, Oct. ... The study is needed because of the dismally low
survival rates for
cardiac arrest; the national ... of life for patients suffering cardiac arrest, low
pressure and head injury by developing new ...
Alimera Reports Results From the Six-Month Interim Readout of the Human PK Iluvien(TM) Study
... therapeutic effect,
up to 36 months for the low
dose and up to 24 months for the high ... were enrolled in the PK study, 20
patients on the low
dose of Iluvien (an approximate 0.23 micrograms ... with the
three- month readout. The percentage of low
dose patients that had an
improvement in BCVA of ...
Analysis of Earlier European Stroke Trial Supports Treatment Regimen for Viprinex(TM) in Current International Phase 3 Clinical Trials
... may be minimized with avoidance of prolonged low
fibrinogen and use of common blood ... were more likely to have had prolonged low
levels, to have received higher ... to revise the dosing regimen to avoid prolonged low
levels and launch new Phase 3 clinical ...
Olanzapine Long-Acting Injection (LAI) Shown to Maintain Treatment Benefit in Schizophrenia for up to Six Months
... every two weeks or 405 mg
every four weeks), to a low
reference dose of olanzapine LAI (45 mg ... events. The rate of discontinuation
over six months of treatment. Incidence of weight ... Other potentially serious adverse events include low
seizures, elevated prolactin ...
Precise Low-Dose Drug Monitoring Essential for Long-Term Kidney Transplant Success
... ability of blood
tests to precisely measure very low
doses of anti-rejection drugs in ... taper down doses of immunosuppressive drugs to as low
level as possible without risking rejection. ... patients on low-dose treatment regimens. "At low
even the slightest variation in ...
Markers in Blood and Spinal Fluid, and a New Imaging Agent, Show Promise for Early Detection of Alzheimer's
... demonstrated in a small group
(n=24) that a low
level of AB42 in cerebrospinal fluid (CSF) is ... PET scan images showing positive PIB-binding) had low
CSF AB42 (36/37,
97%). Those with low
levels of brain amyloid (negative PIB-binding) ...
Alimera Reports Results From the Three-Month Interim Readout of the Human PK Medidur(TM) FA Study
... were enrolled in this trial, 20
patients on the low
dose (an approximate 0.23 microgram per day dose) ... therapeutic effect, up to 24
months for the low
dose and up to 36 months for the high dose. ... from the PK Study indicated 20 percent
of the low
dose patients and 18 percent of the high dose ...
Olanzapine Long-Acting Injection (LAI) Data Presented at First Annual Schizophrenia International Research Society Conference
... four weeks, or 300 mg every two
weeks), or to a low
reference dose of olanzapine LAI (45 mg every ... At 160 weeks, the discontinuation rate was low
(39.6 percent). The most
common reasons for ... Other potentially serious adverse events include low
seizures, elevated prolactin ...