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Economy is Driving Many Osteoporotic Women to Retire Later - But Their Ability to Work May Be Undermined by Sub-Optimal Management of Their Disease

... Almost 34 million Americans are estimated to have low bone mass, placing them at increased risk for ... Bone Health: The State of Osteoporosis and low Bone Mass in Our Nation is an update to the ... at high risk for developing osteoporosis due to low bone mass. Prevalence estimates are based on ...

Prospective Clinical Advantages of Trabecular Metal(TM) Technology Highlighted in Comparative Study

... of the Indiana Research Foundation describes the low stiffness and osteoconductive properties of ... findings confirmed initial assumptions that the low stiffness properties of this porous metal ... to directly compare bone-remodeling effects of a low stiffness porous metal construct to more rigid ...

June 2009 Mayo Clinic Women's HealthSource Highlights Summer Skin Problems, Low Vision and Pilates

... Minn. -- Many devices can help people with low vision -- a permanent partial loss of eyesight ... of Mayo Clinic Women's HealthSource discusses low vision, what it is, the causes and the ... surgery don't improve vision sufficiently. low vision is not the normal difficulty reading the ...

Relievant Medsystems Announces Completion of $20 Million Financing

... a novel, minimally invasive treatment for chronic low back pain, reported today that it has completed a ... the launch of our Intracept(TM) System to treat low back pain," commented Paul Goeld, President and ... effectiveness of our technology." Chronic low back pain impacts nearly one-third of the ...

Pixantrone in Combination with Chemotherapy Regimens Produces Overall Response Rates of 58-74% with Complete Remission Rates of 37-57% in Relapsed/Refractory Aggressive or Indolent NHL

... by the authors to underlie the drugs' low cardiotoxicity profile in preclinical animal ... by the FDA, the failure of pixantrone to have a low cardiotoxicity profile or to produce low cardiac toxicity, the failure of pixantrone to ...

Dainippon Sumitomo Pharma Announces Lurasidone Phase III Data in Patients With Schizophrenia

... was well-tolerated and had a relatively low discontinuation rate. The findings were presented ... showed that lurasidone was well tolerated with a low propensity for EPS, QTc interval changes and ... noradrenalin alpha(2c) receptors. Lurasidone has low affinity for histamine H(1), and cholinergic M(1) ...

RAPAFLO(TM) (silodosin) Provides Rapid and Sustained Benign Prostatic Hyperplasia (BPH) Symptom Relief in as Little as Three Days

... of the targeted prostatic muscle tissue, with a low incidence of vasodilatory and orthostatic ... and placebo-treated patients were similar and low (2.6% and 1.5%, respectively). In addition, the ... The incidence of treatment-related dizziness was low and only slightly higher among RAPAFLO(TM) than ...

Three Clinical Presentations on Tapentadol Extended Release Tablets for Chronic Pain Featured at 2009 American Pain Society Annual Meeting

... challenge in the United States, and chronic low back pain is the most common cause of disability ... release tablets to treat patients with chronic low back pain, including pivotal Phase 3 safety, ... Efficacy and Safety of Tapentadol ER for Chronic low Back Pain: Results of a Randomized, Double-blind, ...

Lack of Food Variety Puts Kids With Autism at Risk for Poor Nutrition

... be at risk for nutrition problems. Kids with low food variety scores who are at risk could then be ... the red blood cells of children with autism have low levels of a fatty acid linked to cognitive ... report, warrants further research into how the low fatty acid levels may trigger biochemical changes ...

AstraZeneca Submits NDA for Low Dose Aspirin/Esomeprazole Combination Product

... (FDA) seeking approval for a product combining low dose aspirin with esomeprazole magnesium for the risk reduction of low dose aspirin-associated gastric and/or duodenal ... magnesium) for the risk reduction of low dose aspirin-associated gastric and/or duodenal ...

New Weight Loss Hope for People with Diabetes

... loss with exercise. NutriSystem D is based on a low Glycemic Index diet that integrates good carbohydrates into its meal plan. It's also low in fat and high in fiber. The Glycemic Index ... that emphasize healthful whole grains, as well as low fat ...

Newly Published Phase III Study Shows Arzoxifene Significantly Increased Bone Mineral Density

... (BMD) in postmenopausal women with normal or low bone mass, versus placebo. In addition, ... in postmenopausal women with osteoporosis or low bone mass. These data are from the ... in postmenopausal women with osteoporosis or with low bone density. Results from that trial are ...

CRESTOR(R) Reduced CV Risk in Patients Achieving Low LDL and hsCRP Targets in New JUPITER Analysis

... of the JUPITER study show that patients with low to normal cholesterol levels and elevated high ... patients treated with rosuvastatin who achieved low levels of LDL-C and hsCRP had a greater reduction ... major cardiovascular events in patients with low to normal LDL-C but at increased ...

CRESTOR(R) Reduced Risk of Blood Clots in the Veins

... compared to placebo among men and women with low to normal cholesterol levels and ... major cardiovascular events in patients with low to normal LDL-C but at increased cardiovascular ... one other risk factor including hypertension, low HDL-C, family history of premature coronary heart ...

SYNTAX Analysis Finds Treatment With TAXUS(R) Express2(TM) Stents More Cost Effective Than Bypass Surgery in Many Patients With Complex Coronary Artery Disease

... more cost effective than CABG in patients with low or moderate coronary lesion complexity. CABG was ... outcomes between PCI and CABG in patients with low or moderate lesion complexity," said Keith D. ... for both PCI and CABG. In those patients with low or moderate lesion complexity, PCI was favored, ...

Worldwide Cost Estimate for Alzheimer's and Dementia Is US$315.4 Billion

... to 3,000 people over 65 years old in each of nine low and middle income countries (China, India, ... the prevalence of dementia in regions with low awareness of this emerging public health ... lack of education, lack of exercise, depression, low birth weight for gestational age, and smaller ...

Alimera Reports Favorable Safety and Efficacy Results From the 12-Month Interim Readout of the Human PK Iluvien(TM) Study

... were enrolled in the PK Study, 20 patients on the low dose of Iluvien (an approximate 0.23 micrograms ... to intraocular pressure (IOP) were seen in low dose patients, and 23.5 percent of the high dose ... or greater over baseline and 23.1 percent of the low dose patients had an improvement in BCVA of 15 ...

Diabetes Patients with High Triglycerides and Low HDL Cholesterol Get the Most Benefit From Fenofibrate Treatment: New Data From the FIELD Study

... triglyceride (2.3 mmol/L-200mg/dL or higher) and low high-density lipoprotein (HDL) ... an abnormal combination of high triglycerides and low HDL cholesterol. Population studies have shown ... lower triglyceride, and 40% higher in those with low HDL cholesterol (<0.96 mmol/L-37mg/dL) than in ...

Nplate(R) Approved in the European Union for the Treatment of Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

... is a serious autoimmune disorder characterised by low platelet counts in the blood (thrombocytopenia), ... are destroyed by the patient's own immune system. low platelet counts leave adult ITP patients open to ... processes in ITP are unable to compensate for low levels of platelets in the blood. Increasing the ...

Medgenics Announces Positive Data From Phase I/II Clinical Trial of EPODURE Treatment of Anemia in Chronic Kidney Disease

... Review Board confirms safety and efficacy of low dose and approves continuation of trial ... of EPODURE, producing and delivering the low dose of 18-25 IU/kg/day of the protein ... up to several times per week, and the comparable low dose does not result in sufficient hemoglobin ...

Intra-Cellular Therapies Announces Successful Outcome of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia

... (DPPM) for the treatment of schizophrenia. A low dose formulation of ITI-007 (formerly referred to ... available drug candidate being evaluated at low doses in patients with SMI. An interim analysis ... ITI-007 to potently antagonize 5HT2A receptors at low doses ...

ESBATech's Antibody Fragment Enters Phase I/IIa Clinical Development in Osteoarthritis with the Potential for Disease-Modifying Activity

... half life, systemic exposure of ESBA105 is very low as compared to traditional TNF alpha inhibitors. ... the targeted sites, in combination with extremely low systemic load, in order to achieve low risk of systemic drug reactions using topical and ...

Three Clinical Studies of bioTheranostics Molecular Breast Cancer Diagnostics Presented at San Antonio Breast Cancer Symposium

... DX Recurrence Score (RS) of high, intermediate or low was previously reported. The study found that ... an intermediate Oncotype DX recurrence score into low and high risk groups. "We know the best ... tumors. Patients whose tumors expressed no or low levels of HOXB13 had a clear benefit from ...

Agendia's Breast Cancer Test MammaPrint(R) Identifies New Subset of Low Risk HER2+ Patients

... substantial group of traditionally miscategorized low risk HER2+ patients. Agendia's highly accurate ... high risk, yet MammaPrint was able to identify a low risk subgroup of HER2+ patients, who ... HER2/NEU positive patients, MammaPrint(R) low risk patients had no relapse. The results ...

Long-term Follow Up Interim Data Show Nplate(TM) Increased and Sustained Platelet Counts in Adult Chronic ITP Patients

... are destroyed by the patient's own immune system. low platelet counts leave adult ITP patients open to ... in ITP are also unable to compensate for low levels of platelets in the blood. Increasing the ... ITP, the incidence of hematologic malignancy was low and similar between Nplate and placebo. ...

Novel Therapeutic Approaches May Transform Treatment and Improve Patient Outcomes in Several Platelet Disorders

... a group of bleeding disorders characterized by a low number of platelets in the blood, will be ... are typically classified by one of three causes: low production of platelets in the bone marrow, ... can be safely and effectively transfused with a low dose of platelets, a strategy that can reduce ...

Lilly Withdraws Application for Additional U.S. Indication for Cymbalta(R) for Chronic Pain

... didn't meet its primary endpoint -- in chronic low back pain. In discussions between Lilly and the ... V. et al. Efficacy of Duloxetine in Chronic low Back Pain. Poster presented at the ... Placebo in the Treatment of Chronic low Back Pain. Poster presented at the 12th World ...

Nplate(TM) (Romiplostim) Receives Positive Opinion for Marketing Authorisation in the European Union

... destroyed by the patient's own immune system. low platelet counts leave adult ITP patients open to ... processes in ITP are unable to compensate for low levels of platelets in the blood. Increasing the rate of platelet production may address low platelet levels associated with ITP. ...

Seniors Can Be Heartened by New Study on Statins

... week, found the benefits even for people with low cholesterol and no major risk for heart disease. ... this study, even people who believe they are at low risk for a heart attack could benefit from taking ... "This study shows that even if you have low cholesterol levels, you aren't safe from heart ...

New Analysis Shows Troubling Trend in Triglyceride Levels May Be Linked to Rising Rates of Obesity

... heart disease. Other studies have shown that low HDL is predictive of cardiovascular events even ... with a combination of high triglycerides and low levels of HDL doubled from two to four percent, ... 8.5 to 23 hours. High triglycerides and LDL and low HDL levels were characterized in the analysis as ...

U.S. Navy and U.S. Army to Develop Dengue DNA Vaccine Formulated With Vical's Vaxfectin(R) Adjuvant

... was safe and well-tolerated at both the 1 mg low dose and 5 mg high dose tested, but even at the high dose induced only low levels of neutralizing antibody titers in less ... extensive bleeding, and shock caused by extremely low blood pressure. Dengue shock syndrome most often ...

CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years

... of Colorado School of Medicine. CIMZIA had a low occurrence of treatment discontinuation due to ... the two main phase III trials showed there was a low incidence of injection site burning and stinging (n=<3 new cases /100 patient-years) and a low level of discontinuations due to adverse events ...

Whatcom County, Washington Participating in NIH Study of Cardiac Arrest Resuscitation Techniques

... advances study Study needed because of low cardiac arrest survival rates MINNEAPOLIS, Oct. ... The study is needed because of the dismally low survival rates for cardiac arrest; the national ... of life for patients suffering cardiac arrest, low blood pressure and head injury by developing new ...

Alimera Reports Results From the Six-Month Interim Readout of the Human PK Iluvien(TM) Study

... therapeutic effect, up to 36 months for the low dose and up to 24 months for the high ... were enrolled in the PK study, 20 patients on the low dose of Iluvien (an approximate 0.23 micrograms ... with the three- month readout. The percentage of low dose patients that had an improvement in BCVA of ...

Analysis of Earlier European Stroke Trial Supports Treatment Regimen for Viprinex(TM) in Current International Phase 3 Clinical Trials

... may be minimized with avoidance of prolonged low levels of fibrinogen and use of common blood ... were more likely to have had prolonged low fibrinogen blood levels, to have received higher ... to revise the dosing regimen to avoid prolonged low fibrinogen levels and launch new Phase 3 clinical ...

Olanzapine Long-Acting Injection (LAI) Shown to Maintain Treatment Benefit in Schizophrenia for up to Six Months

... every two weeks or 405 mg every four weeks), to a low reference dose of olanzapine LAI (45 mg ... events. The rate of discontinuation was low over six months of treatment. Incidence of weight ... Other potentially serious adverse events include low blood pressure, seizures, elevated prolactin ...

Precise Low-Dose Drug Monitoring Essential for Long-Term Kidney Transplant Success

... ability of blood tests to precisely measure very low doses of anti-rejection drugs in ... taper down doses of immunosuppressive drugs to as low a level as possible without risking rejection. ... patients on low-dose treatment regimens. "At low doses, even the slightest variation in ...

Markers in Blood and Spinal Fluid, and a New Imaging Agent, Show Promise for Early Detection of Alzheimer's

... demonstrated in a small group (n=24) that a low level of AB42 in cerebrospinal fluid (CSF) is ... PET scan images showing positive PIB-binding) had low CSF AB42 (36/37, 97%). Those with low levels of brain amyloid (negative PIB-binding) ...

Alimera Reports Results From the Three-Month Interim Readout of the Human PK Medidur(TM) FA Study

... were enrolled in this trial, 20 patients on the low dose (an approximate 0.23 microgram per day dose) ... therapeutic effect, up to 24 months for the low dose and up to 36 months for the high dose. ... from the PK Study indicated 20 percent of the low dose patients and 18 percent of the high dose ...

Olanzapine Long-Acting Injection (LAI) Data Presented at First Annual Schizophrenia International Research Society Conference

... four weeks, or 300 mg every two weeks), or to a low reference dose of olanzapine LAI (45 mg every ... At 160 weeks, the discontinuation rate was low (39.6 percent). The most common reasons for ... Other potentially serious adverse events include low blood pressure, seizures, elevated prolactin ...
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