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PLC Medical Systems to Demonstrate RenalGuard(R) at EuroPCR 2009

... an assessment of the potential benefits of induced diuresis with matched hydration therapy compared ... in renal function. The CIN-prevention therapy of induced diuresis and matched hydration therapy will be ... safe and effective prevention device for contrast induced nephropathy may not be completed in a timely ...

Affitech-Discovered Anti-PS Antibodies in Development by Peregrine Pharmaceuticals Show Excellent Functionality in Preclinical Studies

... showing that the anti-PS antibody induced a sequential release of cytokines and ... the researchers showed that in vitro, PGN635 induced antibody-dependent death of endothelial cells, ... cytokines and chemokines. PGN632 also induced an increase in the expression of cell-surface ...

Studies Presented at AACR Annual Meeting Highlight Multiple Immunomodulatory Mechanisms of Peregrine's PS-Targeting Antibodies

... showing that the anti-PS antibody induced a sequential release of cytokines and ... the researchers showed that in vitro , PGN635 induced antibody-dependent death of endothelial cells, ... cytokines and chemokines. PGN632 also induced an increase in the expression of cell-surface ...

Novavax Presents Favorable Results from Phase I/IIa Pandemic Influenza Vaccine Program at World Health Organization Conference

... The vaccine, which does not contain an adjuvant, induced robust hemagglutination inhibition (HAI) ... strain. Additional immunological responses induced by the other components of the vaccine are being ... previously announced, this vaccine candidate also induced strong HAI titers against strains that cause ...

Vical Pandemic Influenza Vaccines Achieve T-Cell Responses and Cross-Clade Reactivity in Humans

... H5N1 pandemic influenza DNA vaccines induced T-cell responses against a matching strain of ... H5N1 pandemic influenza DNA vaccine induced T-cell responses against the H5 antigen in 75% to ... influenza virus strain, A/Vietnam/1203/04, also induced antibody responses against the H5N1 influenza ...

Epidemics of Both Type 1 Diabetes (Insulin Dependent) and Type 2 Diabetes (Obesity Related) Are Linked to Immunization

... as type 1 diabetes. In other individuals vaccine induced inflammation is countered by release of cortisol ... Classen has previously demonstrated vaccine induced type 1 diabetes has a strong genetic/familial ... have a much greater risk of developing vaccine induced type 1 diabetes. In a previous ...

Technique for Rapidly Reprogramming Adult Cells Into Stem Cells Published in PLoS Biology

... adult mammalian cells into authentic induced pluripotent stem (iPS) cells has been published ... in current approaches for producing such cells. induced pluripotent stem cells are expected to have ... and efficient route to obtaining authentic induced pluripotent stem cells and will form the basis ...

Alba Therapeutics Presents New Data for Larazotide Acetate at the 2008 American College of Gastroenterology Annual Scientific Meeting

... Larazotide Acetate Prevented Immunologic Changes induced by Gluten in Patients with Celiac ... acetate prevented immunologic changes induced by gluten in patients with celiac disease. In ... Acetate Prevents Immunologic Changes induced by Gluten Challenge in Celiac Disease Patients" ...

Sound Pharmaceuticals Files Second IND with the FDA for the Prevention of Chemotherapy Induced Hearing Loss in Advanced Stage Cancer

... of ebselen for the prevention of chemotherapy induced hearing loss or ototoxicity. The oral ... US Navy for the prevention and treatment of noise induced hearing loss. Currently there are no FDA approved drugs for the prevention and treatment of drug induced hearing loss or ototoxicity. SPI hopes to ...

The New England Journal of Medicine Publishes Study Investigating the Safety and Efficacy of Baxter's Cell-Based Pandemic, Avian Flu Vaccine

... publication showing the candidate vaccine induced neutralizing antibodies against widely divergent ... side effects. In this Phase I/II study, CELVAPAN induced an immune response that is similar to the body's ... the non- adjuvanted formulations induced the highest rates of subjects with a titer ...

Pharmacyclics Novel Btk Inhibitor Shows Efficacy in Preclinical Models of Rheumatoid Arthritis and Lymphoma

... of Bruton's tyrosine kinase, or Btk, in collagen induced arthritis, an established animal model for ... with PCI-32765 reduced inflammation and induced regression of disease with approximately 50% ... also inhibited the proliferation of, and induced apoptosis in, multiple B-cell lymphoma cell lines ...

Imaging Results From the ADAGIO-LIPIDS Reveal That Effects of Rimonabant on Cardiometabolic Risk Profile Include Loss of Visceral Fat and Mobilization of Liver Fat

... had no effect on LDL-cholesterol levels, the drug induced a major shift in the distribution of the size of ... We found that rimonabant therapy for one year induced a preferential mobilization of visceral adipose ... that we report for the first time that rimonabant induced a significant mobilization of liver fat (decrease ...

Cardium's Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack

... evaluated the effect of early and rapid cooling induced by a combination of cold saline infusion along ... imaging (MRI). Rapid hypothermia, induced by the infusion of one liter of cold saline in ... arm will receive routine standard of care without induced hypothermia. The trial will employ cardiac MRI to ...

Pharmacopeia Announces Third Quarter 2007 Financial Results

... to block the increase in blood pressure induced by administration of angiotensin II (AII) to ... a statistically significant (p induced increase in blood pressure. Additionally, the ... its ability to block the angiotensin II- induced blood pressure increase for 24 hours. -- ...

Quark Pharmaceuticals Extends Research Agreement with State University of New York for Proprietary siRNA Compounds for Acute Hearing Loss

... and other molecules in preventing chemotherapy induced hearing loss. Based on these studies, ... causes of acute hearing loss, is believed to be induced by molecular mechanisms most likely associated ... cochlear hair cells from apoptotic cell death induced by the chemotherapeutic agents, cisplatin and ...

Keryx Biopharmaceuticals, Inc. Commences Phase 1 Study of KRX-0401 (Perifosine) in Recurrent Pediatric Solid Tumors at Memorial Sloan-Kettering Cancer Center

... Cancer Institute demonstrated that single agent perifosine not only induced tumor regression and delayed tumor growth, but that perifosine also ... 2 study conducted at Memorial Sloan-Kettering Cancer Center, perifosine induced responses and delayed disease progression in adult patients with advanced ...

Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support

... Fate Therapeutics is interrogating adult stem cell biology and applying induced pluripotent stem (iPS) cell technology to develop Stem Cell Modulators ... program to provide its partners with first access to the most advanced induced pluripotent stem (iPS) cell technologies for drug discovery and ...

R&D Spending by U.S. Biopharmaceutical Companies Reaches Record Levels in 2008 Despite Economic Challenges

... sector also supported 1 million indirect jobs and 1.5 million induced jobs that year. Perhaps one of the strongest signs of potential for ... of the economy in 2006. The same ripple effect that supported indirect and induced jobs also had a ripple effect on GDP, with every dollar contributed to GDP ...

Keryx Biopharmaceuticals, Inc. Reports Phase 1/2 Data on KRX-0401 (Perifosine) at 50th Annual Meeting of American Society of Hematology

... but these are either mild or non-existent in lower doses that have induced tumor regression. Responses have been seen with both daily and weekly ... regimens were better tolerated. In Phase 1/2 trials, KRX-0401 has induced tumor regressions and/or caused disease stabilization in a variety of ...

ImmunoVaccine Technologies' DepoVax(TM) Shows Positive Results for Cancer and Infectious Diseases

... tested, as early as 18 days and for at least 20 weeks, antibody titers induced by the depot vaccine were 10-15 times higher than a single dose of the control alum vaccine. The vaccine induced quick and strong specific immunity against the avian influenza antigen. In ...

Quark Pharmaceuticals Announces First RNAi Drug Candidate Having a Novel, Proprietary Structure Covered by Quark Intellectual Property

... de Montreal, its effectiveness was examined in a model of RGC death induced by axotomy of the optic nerve. QPI-1007 displayed neuroprotective activity ... protected retinal neurons against delayed degeneration and reduced injury induced RGC death in vivo, the hallmarks of glaucoma and acute injuries such as ...

Novavax Announces Favorable Results from Phase I/IIa Pandemic Influenza Vaccine Program

... (VLP) vaccine candidate. The vaccine, which does not contain an adjuvant, induced robust neutralizing antibody responses. Novavax's VLP candidate is ... (M1) of the H5N1 A/Indonesia strain. Additional immunological responses induced by each of the components of the vaccine are being evaluated including ...

BRIDION(R) (sugammadex) Injection - First and Only Selective Relaxant Binding Agent - Approved in European Union

... designed to rapidly reverse both moderate and deep muscle relaxation induced by the commonly used muscle relaxants rocuronium bromide ... approved in the European Union (EU) for reversal of neuromuscular blockade induced by rocuronium or vecuronium. In children and adolescents, BRIDION is only ...

Michael J. Fox Foundation Funds $1.1 Million for Cutting-Edge Approaches to Parkinson's Disease Under Rapid Response Innovation Awards 2008

... NEW YORK, July 29 /PRNewswire-USNewswire/ -- Gene silencing techniques and induced pluripotent stem cell technology are among the cutting-edge approaches to ... UK) are conducting two separate investigations using newly discovered induced pluripotent stem cell (iPS) technology to shed greater light on the ...

Keryx Biopharmaceuticals, Inc. Announces Phase 2 Results on KRX-0401 (Perifosine) in Patients with Relapsed/Refractory Waldenstroms Macroglobulinemia at the 44th Annual Meeting of the American Society of Clinical Oncology

... but these are either mild or non-existent in lower doses that have induced tumor regression. Responses have been seen with both daily and weekly ... daily regimens were better tolerated. In Phase 1/2 trials, KRX-0401 has induced tumor regressions and/or caused disease stabilization in a variety of ...

Keryx Biopharmaceuticals, Inc. Announces Poster Presentation Highlighting Observed Clinical Activity of KRX-0401 (Perifosine) at the American Society of Clinical Oncology Meeting in Chicago, Illinois

... but these are either mild or non-existent in lower doses that have induced tumor regression. Responses have been seen with both daily and weekly ... daily regimens were better tolerated. In Phase 1/2 trials, KRX-0401 has induced tumor regressions and/or caused disease stabilization in a variety of ...

PLC Systems Announces Approval of First European Study to Evaluate RenalGuard(TM)

... randomized trial to provide an assessment of the potential benefits of induced diuresis with matched hydration therapy, compared to standard overnight ... with baseline impairment in renal function. The CIN-prevention therapy of induced diuresis and matched hydration therapy will be provided using RenalGuard. ...

CERVARIX(R) Shown to Provide Longest Duration of Sustained Neutralizing Antibodies to Date

... vaccine was sustained and 11 times higher than the total antibody levels induced after natural infection for up to 6.4 years. This new data confirms ... women aged 15-25 years. During the same period that the candidate vaccine induced sustained high antibody levels for both virus types 16 and 18, the vaccine ...

Novavax Reports Positive Results from Preclinical Studies of its VLP-based Trivalent Seasonal Influenza Vaccine Candidate

... (VLPs) representing the H3N1, H1N1, and B virus strains. The vaccine induced protective antibody levels against each of the three strains represented ... licensed split and subunit influenza vaccines. The vaccine candidate also induced protective antibody titers against a drifted strain in approximately 50% ...

Nventa Announces Positive Interim Immunological Data From HspE7 Phase 1 Cervical Dysplasia Trial

... preclinical models and support the compound's potential to treat HPV-16 induced CIN. HPV-16 is the most common subtype of the HPV virus and is responsible ... the body's natural immune system; the potential of HspE7 to treat HPV-16 induced CIN; that the results may correlate to the activity of the drug in future ...

St. Jude Finds Signaling System That Halts the Growth of a Childhood Brain Cancer

... BMP2, BMP4 and BMP7, halted the growth of medulloblastoma tumors and induced the malignant cells to develop into normal neurons. "We think we have ... cells and showed that the transfer not only halted tumor growth, but induced the cancer cells to change into neurons. Other authors of this study ...

Takeda Doses First Patient in a U.S. Phase 1 Study of Hematide(TM) to Treat Chemotherapy Induced Anemia

... to begin the first U.S.-based clinical trial of Hematide in chemotherapy induced anemia (CIA)," said Masaomi Miyamoto, Ph.D., general manager of Takeda's ... Takeda's efforts in the clinical development of Hematide in chemotherapy induced anemia. We are pleased with the data generated to date from our trial in ...

Prescient Medical, Inc. Acquires New Technology to Detect Inflammation in Coronary Blood Vessels

... Time Resolved Light induced Fluorescence Spectroscopy (TR-LIFS) to be Combined with Other PMI ... ultra-short light pulses. The new technique, called Time Resolved Light induced Fluorescence Spectroscopy (TR-LIFS), exploits the phenomenon that ...

Addition of INTEGRILIN(R) (Eptifibatide) to Bivalirudin Plus Standard of Care Inhibits Platelet Aggregation in Patients Undergoing Elective Coronary Stenting

... statistically significant for all measurements of platelet aggregation induced by multiple agonists. "The results reflect the importance of a GP ... alone produced greater relative inhibition of platelet aggregation induced by 5 or 20 uM ADP, 15 or 25 uM TRAP, or collagen (p<0.01 for all). ...

Quark Pharmaceuticals Signs Collaboration Agreement With University of Michigan for Development of Proprietary SiRNA Compounds for Noise-Induced Hearing Loss

... Quark Expands Hearing Loss Program With Novel SiRNA Approaches To Noise- induced Hearing Loss With Its First Drug Candidate, AHLI-11, For The Prevention ... AHLi-11, for the prevention of cisplatin (a chemotherapeutic agent) induced ototoxic hearing loss. About Quark Pharmaceuticals, Inc. Quark ...

One Year Study of Exenatide Treatment Showed Improved Beta-Cell Function

... - 0.24 vs. 1.31 + or - 0.07, respectively, p<0.0001). First phase glucose induced C-peptide secretion was 52 percent greater after one year of exenatide ... improved beta-cell function as measured by both glucose and arginine induced insulin secretion." The side effects associated with exenatide treatment ...

One Year Study of Exenatide Treatment Showed Improved Beta-Cell Function

... - 0.24 vs. 1.31 + or - 0.07, respectively, p<0.0001). First phase glucose induced C-peptide secretion was 52 percent greater after one year of exenatide ... improved beta-cell function as measured by both glucose and arginine induced insulin secretion." The side effects associated with exenatide treatment ...

Amgen Announces Positive Top-Line Results for Denosumab in Trial for Delay of Skeletal Related Events in Bone Metastases Patients Compared to Zometa(R)

... pioneering medicines to patients with unmet medical needs. Amgen is studying denosumab in numerous tumor types across the spectrum of cancer induced bone disease. Over 11,000 patients have been enrolled in the denosumab oncology clinical trials testing the drug for bone loss and destruction ...

Injection Reverses Heart-Attack Damage

... fetal heart (and in injured skeletal muscle) but scarce in adult hearts. When the patch was placed over the site of cardiac injury in rats, it induced cardiomyocyte proliferation and improved heart function ( Nature Medicine 2007; 13:962-9). Similar results were seen in larger animals, and ...

Denosumab Demonstrates Superiority Over Zometa(R) in Pivotal Phase 3 Head-to-Head Trial in Breast Cancer Patients With Bone Metastases

... pioneering medicines to patients with unmet medical needs. Amgen is studying denosumab in numerous tumor types across the spectrum of cancer induced bone disease. Over 11,000 patients have been enrolled in the denosumab oncology clinical trials testing the drug for bone loss and destruction ...
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(Date:7/30/2014)... humans figured out how to create colors, nature had ... wings of many different hues, for example. Now scientists ... environmentally friendly way to make colored plastics. Their paper ... of materials rather than dyes, to produce color ... , N. Asger Mortensen, Anders Kristensen and colleagues point ...
(Date:7/30/2014)... professor from Wayne State University,s College of Engineering ... Science Foundation for the project, "Nanoparticle-directed synthesis of ... Science Foundation, nanotechnology is the creation and utilization ... properties and functions. A major bottleneck in scaling ... that connect different functional materials into one device. ...
(Date:7/30/2014)... therapies for spinal cord injury (SCI), traumatic brain injury ... great deal has been learned over the past 30 ... factors that regulate axon growth, but this large body ... therapeutics. Prof. Lemmon and his team from University of ... root causes, but a consensus is emerging that one ...
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(Date:7/30/2014)... Responding to the call to ... to an increasingly diverse patient population, three leading ... expertise to the publication of a new textbook ... and Cultural Competence in Health Care: A Systems ... a professor in the Management Division at the ...
(Date:7/30/2014)... returning National Guard soldiers were more likely to ... life setbacks, including job loss, legal problems, divorce, ... military families. Results of the study by researchers ... are published online in the American Journal ... a major concern for reservists returning home. Nearly ...
(Date:7/30/2014)... Recently, the Kansas Health Image ... start-up fees for hospitals and clinics who request ... September 30, 2014. , Modern healthcare providers are ... complexity of digital patient information, often referred to ... data silos. , Traditional health IT solutions, including ...
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(Date:7/30/2014)... Daily Gossip mentions that the "Panic Away" method developed ... stop anxiety and eliminate all associated symptoms. It has been ... 150,000 people in getting their lives back. , The Panic ... system that will teach sufferers different techniques on how to ... to access, as it is available in a complex guide. ...
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