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Vectibix(R) in Combination With Chemotherapy Significantly Improved Progression-Free Survival in First-Line Metastatic Colorectal Cancer

... About Vectibix Vectibix is the first fully human anti-EGFR antibody approved by the U.S. Food and ... develops, manufactures and delivers innovative human therapeutics. A biotechnology pioneer since ... candidates in humans. The complexity of the human body cannot be perfectly, or sometimes, even ...

DNA Helps Reunite Children With Their Families

... are under 17. It is estimated that by 2010, human trafficking will be the No. 1 crime worldwide. ... Genetics and co-director of the UNT Center for human Identification at the University of North ... humanitarian effort using DNA testing to deter human trafficking of children and help reunite abducted ...

Scientists Discover Origin of Malaria

... , that is closely related to the dominant human malaria parasite, Plasmodium falciparum , most ... that these parasites had co-existed separately in human and chimpanzee ancestors for the last 5 million ... is a much broader range of close relatives to the human parasite than were previously recognized, some of ...

Amgen Announces Positive Top-Line Results for Denosumab in Trial for Delay of Skeletal Related Events in Bone Metastases Patients Compared to Zometa(R)

... in Bone Biology Denosumab is the first fully human monoclonal antibody in late stage clinical ... Amgen discovers, develops and delivers innovative human therapeutics. A biotechnology pioneer since 1980, ... candidates in humans. The complexity of the human body cannot be perfectly, or sometimes, even ...

Access Pharmaceuticals Provides Update on ProLindac Clinical Development Program

... has shown to be active in many solid tumors in human clinical studies. Access has commenced a new ... has shown to be active in many solid tumors in human clinical studies. Platinum drugs are one of the ... of solid tumors in both preclinical models and in human trials. Access believes that ProLindac's unique ...

Shire Reports Positive Results From First of Three Phase III Trials of velaglucerase alfa for Type 1 Gaucher Disease and Provides Important Updates on Interactions With FDA

... said Sylvie Gregoire, President of Shire human Genetic Therapies. "This data are consistent ... cell line. The enzyme produced has the exact human amino acid sequence and carries a human glycosylation pattern. Phase III Study ...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... of novel genetically modified animal models of human disease. ZFN technology will make the generation ... said Howard Jacob, Ph.D. Director of the human and Molecular Genetics Center at the Medical ... many traits and are ideal subjects for modeling human diseases. Extensive genetic characterization has ...

Octapharma Accepting Applications for Research Grants on Immunotherapy, Coagulation Disorders and Critical Care

... clinical or pre-clinical research focused on human protein therapies in coagulation disorders, ... patients with the safest, highest quality human protein therapies available is stronger than ... development, production and sale of high quality human protein therapies, including immune globulin ...

Awardees for the 2009 Young Investigator Grant for Probiotics Research Announced

... conditions, drug treatments, or infections, human gut microbiota can become unbalanced. This ... new evidence on the benefits of probiotics on human health continues to emerge," said Sven ... and the mechanisms in which they promote human health." "We are very pleased with the ...

Lexicon's Drug Candidate LX1032 for Carcinoid Syndrome Receives Orphan Drug Designation From EMEA

... and developing breakthrough treatments for human disease, announced today that it has received ... the evaluation and supervision of medicines for human and veterinary use. The goal of EMEA's orphan ... and developing breakthrough treatments for human disease. Lexicon currently has five drug ...

Human Genome Sciences and GlaxoSmithKline Announce Positive Phase 3 Study Results for BENLYSTA(TM) in Systemic Lupus Erythematosus

... and LONDON, July 20 /PRNewswire-FirstCall/ -- human Genome Sciences, Inc. (Nasdaq: HGSI ) and ... Belimumab is an investigational human monoclonal antibody drug that specifically ... and is committed to improving the quality of human life by enabling people to do more, feel better ...

BioCryst Pharmaceuticals Reports Positive Results of Shionogi & Co. Sponsored Phase 3 Studies of i.v. Peramivir for Influenza

... clinical activity and safety in prior human studies. In laboratory tests, peramivir has shown ... alliances with the U.S. Department of Health and human Services, Shionogi & Co., Ltd., Green Cross ... licensees may not commence as expected additional human clinical trials with our product candidates; that ...

Oncolytics Biotech(R) Inc. Announces Publication of Research on Synergistic Activity of Reovirus and Chemotherapy in NSCLC

... work examining reovirus and chemotherapy against human non-small cell lung cancer (NSCLC). The paper, ... includes a variety of Phase I/II and Phase II human trials using REOLYSIN(R), its proprietary formulation of the human reovirus, alone and in combination with radiation ...

Shire Receives Fast Track Designation for velaglucerase alfa for Gaucher Disease

... cell line. The enzyme produced has the exact human amino acid sequence and carries a human glycosylation pattern. Background on ... attention deficit hyperactivity disorder (ADHD), human genetic therapies (HGT) and gastrointestinal ...

Schering-Plough Expands Vicriviroc Phase II Study in Treatment-Naive Patients With HIV

... that work to inhibit viral replication within human CD4+ cells, most of which are part of the immune ... AIDS Society and Department of Health and human Services guidelines for antiretroviral therapy. ... applies its research-and-development platform to human prescription and consumer products as well as to ...

University of Michigan Study Shows SEQUENOM's MassARRAY Technology Identifies HPV Infections Missed by Standard Hybridization Test

... determined to be negative for the presence of human papillomavirus (HPV) in the cervix, via the most ... for Quantitative, Type-specific Detection of human Papillomavirus, will be published in the ... the quantity of HPV relative to the number of human cells in the sample, or 'viral load,' we ...

Fruitfly Model of a Neuropathic Disease Demonstrates Novel Role for Proteins in the Family of aTyr Pharma's Product Class

... synthesis machinery found in all organisms, but human synthetases have naturally occurring resected ... of these resect ed prote ins ( resectins ) of human aminoacyl tRNA synthetases with cell signaling ... In this recently published study, a model of a human neuropathy was created in the fruit fly ...

Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM)

... and marketing of proprietary products for human and animal health markets worldwide. The ... personnel and has three operating divisions: human Health, Animal Health, and Food Safety. The ... supported by revenues from marketed products in human and animal health. Bioniche has been named one of ...

Denosumab Demonstrates Superiority Over Zometa(R) in Pivotal Phase 3 Head-to-Head Trial in Breast Cancer Patients With Bone Metastases

... in Bone Biology Denosumab is the first fully human monoclonal antibody in late stage clinical ... Amgen discovers, develops and delivers innovative human therapeutics. A biotechnology pioneer since 1980, ... candidates in humans. The complexity of the human body cannot be perfectly, or sometimes, even ...

Shire has Filed a Treatment Protocol for Velaglucerase Alfa for Gaucher Disease

... cell line. The enzyme produced has the exact human amino acid sequence and carries a human glycosylation pattern. Shire has ... attention deficit hyperactivity disorder (ADHD), human genetic therapies (HGT) and gastrointestinal ...

5-Year Study Published in Diabetologia Demonstrated Long-Term Safety of Lantus(R) Compared to NPH

... not have mitogenic effects different from the human NPH insulin within the eye. "This 5-year ... study with insulin glargine versus NPH human insulin ," said lead investigator Julio ... safety profile of insulin glargine (glargine) and human neutral protamine Hagedorn insulin (NPH) in ...

UNT Health Science Center's Groundbreaking Research Applied to Protecting Brain After Traumatic Injury

... injury. These findings are now being tested on human trauma patients in North Texas. James ... protective effects of rapid estrogen treatment to human patients with severe traumatic brain injury and ... the UNT Health Science Center to these studies in human subjects. If we can administer these drugs to ...

New Data Supports Significant Economic and Clinical Value of MENOPUR(R) in IVF

... today at this year's European Society of human Reproduction and Embryology (ESHRE) congress ... (IVF) treatment MENOPUR (highly-purified human menopausal gonatropin or HP-hMG) offered ... a randomized assessor-blind controlled trial. human Reproduction 2006 Dec; 21(12):3217-27. 5. ...

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... that the Committee for Medicinal Products for human Use (CHMP) of the European Medicines Agency ... and vision. About SIMPONI SIMPONI is a human monoclonal antibody that targets and neutralizes ... applies its research-and-development platform to human prescription and consumer products as well as to ...

Covance Announces Integrated Radiolabeled Clinical Pharmacology Studies

... --Integrated human AME studies comply with recent FDA guidance for ... (MIST). Recent MIST guidance requires earlier human absorption, metabolism and excretion (AME) ... (IND/CTA) submissions. "Integrated human AME services are designed to help reduce the time ...

GeoVax Labs, Inc. Announces Results of 2009 Annual Shareholders Meeting

... biopharmaceutical company developing human vaccines for diseases caused by the HIV-1 (Human ... immune responses being reported in five completed human trials, the advancement of plans to begin human therapeutic [treatment] trials in the U.S., ...

Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) for the Treatment of Fabry Disease

... Trial Update Amicus and its partner, Shire human Genetic Therapies, Inc. (Shire HGT), have ... entered into a strategic collaboration with Shire human Genetic Therapies, Inc., a wholly-owned ... chaperones for the treatment of a range of human genetic diseases. Pharmacological chaperone ...

Cordex Signs European Development Partnership for ATPotent(TM) Sperm Motility Drug

... candidate designed for in vitro (outside of the human body) treatment of sperm in conjunction with ... of adenosine 5'-triphosphate (ATP) for improving human and animal sperm motility and fertilization ... sperm motility or movement, is a common cause of human male infertility. It has been reported in the ...

New Bisphenol A Study Is of Very Limited Relevance to Human Health

... and data so as to be directly relevant to human health. This new study fails to meet these basic ... NIEHS to have very limited value for assessing human health effects since people are orally exposed to ...ans... the study is of very limited relevance to human health, according to the NIEHS guidelines, due to ...

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

... in Subjects with Psoriatic A rthritis Using a human Anti-TNF Monoc L onal Antibody (GO-REVEAL) study, ... from AS. About SIMPONI SIMPONI is a human monoclonal antibody that targets and neutralizes ... applies its research-and-development platform to human prescription and consumer products as well as to ...

The Lancet Publishes Direct Comparison Study Between Liraglutide and Exenatide

... The study compared liraglutide, a human GLP-1 analog, which is under investigation as a ... Once-daily liraglutide is the first human glucagon-like peptide-1 (GLP-1) analog developed ... that the Committee for Medicinal Products for human Use (CHMP) under the EMEA adopted a positive ...

FYI From Human Genome Sciences: GlaxoSmithKline Study Shows GSK's Novel Diabetes Treatment Syncria(R) (Albiglutide) Improves Glucose Control, Reduces Weight

... product generated from the genetic fusion of human albumin and modified human GLP-1 peptide, and is designed to act throughout ... web site at www.hgsi.com . HGS and human Genome Sciences are trademarks ...

Micromet's Blinatumomab Achieves Primary Endpoint in Phase 2 Study with Acute Lymphoblastic Leukemia Patients

... is overexpressed in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also ... the development and commercialization of MT203, a human antibody neutralizing the activity of ... clinical trial with Micromet's glycolipid-binding human antibody MT228 for the treatment of melanoma. ...

Micromet Presents Update on Blinatumomab's Response Rate and Duration in a Phase 1 Study in Non-Hodgkin's Lymphoma Patients

... is overexpressed in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also ... the development and commercialization of MT203, a human antibody neutralizing the activity of ... clinical trial with Micromet's glycolipid-binding human antibody MT228 for the treatment of melanoma. ...

Study Shows GSK's Novel Diabetes Treatment SYNCRIA(R) (albiglutide) Improves Glucose Control and Reduces Weight

... an investigational biological, injectable form of human GLP-1 - a peptide that acts throughout the body ... is the only medication which fuses modified human GLP-1 to human albumin, a protein found in the blood plasma. It ...

PharmAthene Submits Proposal to BARDA in Response to Broad Agency Announcement for Advanced Research and Development for Valortim(R)

... funding to further develop Valortim(R), a fully human monoclonal antibody, for the prevention and ... About Valortim(R) Valortim(R) is a fully human monoclonal antibody generated by Medarex, Inc's ... intravenously and intramuscularly to healthy human volunteers in a completed Phase 1 study, was well ...

Aethlon Medical to Present at the 2009 RedChip Small-Cap Investor Conference on June 16, 2009

... viruses and immunosuppressive particles from the human circulatory system. Additional information can ... viruses and immunosuppressive particles from the human circulatory system. The device targets to ... progression of Hepatitis-C Virus (HCV) and human Immunodeficiency Virus (HIV), and serves as a ...

Medarex Announces Allowance of Investigational New Drug Application for Wholly-Owned Fully Human Anti-CXCR4 Antibody, MDX-1338

... myelogenous leukemia (AML). MDX-1338 is a fully human antibody that targets CXCR4, a chemokine receptor ... the growth of, and even directly kill, selected human tumor cells. The Phase 1, open-label, ... and potential commercialization of fully human antibody-based therapeutics to treat ...

Blanchette Rockefeller Neurosciences Institute and Inverness Medical Innovations to Develop Commercial Test to Detect Early Alzheimer's Disease

... in the world dedicated to the study of human memory and memory disorders, BRNI first ... biomarker showed high accuracy when tested with human skin cells from a tissue bank, as well as for ... institute dedicated to the study of both human memory and diseases of memory. Its primary ...

Scientific Data Relating to Cinryze(TM) Presented at 6th Annual C1 Inhibitor Deficiency Workshop

... Swine'; In this study, 50 units/kg of human C1 inhibitor were infused either IV or SQ into ... caused by a deficiency of C1 inhibitor, a human plasma protein. This condition is the result of a ... acute treatment of HAE. We have not conducted any human studies related to the subcutaneous infusion of ...
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