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Hormones in Medical Technology

When It Comes to Natural Remedies for Hormonal Balance, the Proof Is in the Clinical Research

... formulation of the Peruvian herb maca. hormones are the body's directors, controlling the ... are profoundly important to a woman's health - hormones affect a woman's mood and cognitive function, they directly affect a woman's bone density, and hormones are without a doubt the most important factor of ...

Melanoma and Pregnancy: What Every Woman Needs to Know About the Risks, Prognosis

... been ongoing controversy concerning the effect of hormones on melanoma," said Dr. Driscoll. "Some ... melanomas may grow rapidly and spread due to the hormones associated with pregnancy. While we know that hormones may impact other types of cancer, such as breast ...

TWO NEW KLRI PEER-REVIEWED PUBLICATIONS: Hormone Therapy May Reduce Atherosclerosis in Women Close to Menopause; Growth Hormone May Increase Risk of Diabetes, Improve Lipid Profile in Men

... have not been studied extensively. The body naturally secretes growth hormones to fuel growth through childhood and maintain tissues and organs. Their use as an anti-aging therapy stems from the natural decrease of growth hormones secreted by the body as we reach middle age--replacing them with ...

Addrenex Pharmaceuticals Expands Product Pipeline by Licensing New Drug to Treat Narcolepsy

... from an overactive or improperly regulated adrenergic system, a group of hormones and brain chemical messengers known as neurotransmitters. These hormones and neurotransmitters regulate diverse physiologic functions such as ...

Estrogen Getting Cool Reception From Dermatologists for Mixed Results in Improving Appearance of Skin

... support their use and the known risks of prolonged estrogen therapy -- including an increased risk of breast cancer." Estrogens are a group of hormones that play a key role in regulating many aspects of a woman's overall health, including reproduction. Certain parts of the body contain cells that are ...

R-Tech Ueno, Ltd. Completes Phase 1 Clinical Study on RK-023

... become useful for the patients with androgenetic alopecia as soon as possible. Note: Androgenetic alopecia: Due to the influence of male hormones during and after puberty, thick and long hair does not regenerate but is replaced with thin and short soft hair, and consequently the hair follicles ...

Boehringer Ingelheim Unveils Diabetes Pipeline

... of linagliptin for the treatment of type 2 diabetes." DPP-4 inhibitors are a newer class of oral hypoglycemics that target the incretin hormones GLP-1 and GIP, which are believed to be involved with regulating blood sugar.(2) Linagliptin is a compound discovered by Boehringer Ingelheim ...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

... benefit was seen in patients with functioning tumors (i.e., tumors that are associated with carcinoid syndrome due to the secretion of various hormones that cause symptoms, such as diarrhea or flushing) and non-functioning (non-secreting) tumors. In an analysis of patients with non-functioning ...

Addrenex Pharmaceuticals Reports Positive Results in Second Phase 3 Study of ADHD Medication

... Addrenex Pharmaceuticals. Clonicel is a non-stimulant medication that selectively targets and calms the adrenergic system, a cascade of stress hormones that regulate the body's response to stress and other physiologic factors. An overactive adrenergic system can trigger emotional outbursts, ...

Vantia Therapeutics' Pipeline Continues to Mature

... in Vantia's preclinical pipeline, the company is continuing to generate value from its extensive library of small molecule antagonists of hormones and proteases. Following the completion of the 27-patient Phase IIa trial of VA106483, a vasopressin agonist, results are expected in H1 2009, ...

Modigene Announces Positive Results of Pilot Toxicity Study of Its Long-Acting Human Growth Hormone hGH-CTP

... It has an exclusive license from Washington University to the CTP technology for use with all therapeutic proteins except for the four endocrine hormones licensed to Schering-Plough. ABOUT MODIGENE Modigene Inc. is a biopharmaceutical company applying its patented CTP technology to develop ...

New Study First to Confirm Sandostatin LAR(R) Depot Controls Tumor Growth in Patients With Rare Gastrointestinal Tumors

... tumor within the midgut, were without curative therapeutic options and had tumors that were functionally active (i.e., tumors that secrete various hormones and bioactive amines, causing symptoms such as diarrhea or flushing) or inactive. The study was sponsored by Novartis. The safety findings ...

New Mammography Technology Effective in Detecting Breast Cancer

... a woman's cycle, reading MRI images is extremely difficult," Dr. Schilling said. "This is a significant problem with breast MRI." Because hormones do not have the same effect on PEM results, Dr. Schilling believes the imaging technique could play a significant role both in preoperatively ...

ASGE and The Pancreatic Cancer Action Network Partner to Raise Awareness About Pancreatic Cancer

... the stomach, that is part of the digestive and endocrine systems. The pancreas makes juices that help with digestion (enzymes) as well as important hormones such as insulin that control the level of sugar in the bloodstream. Pancreatic cancer is difficult to diagnose early, as the symptoms are often minor ...

Addrenex Pharmaceuticals Initiates Phase 2 Trial on Its Novel Hypertension Drug, ADX415

... focus of Addrenex is the treatment of medical conditions that arise from an overactive or improperly regulated adrenergic system, a group of hormones produced by the adrenal glands that regulates diverse physiologic functions such as blood pressure, heart rate and response to stress. "Numerous ...

Takeda Submits a New Drug Application in the U.S. for Alogliptin (SYR-322) / ACTOS(R) (pioglitazone HCl) for the Treatment of Type 2 Diabetes

... of the DPP-4 inhibitors class, which are newer oral agents for the treatment of type 2 diabetes. DPP-4 inhibitors slow the inactivation of incretin hormones GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). The incretins play a major role in regulating blood glucose ...

Addrenex Pharmaceuticals Announces Positive Phase III Clinical Results for Clonicel to Treat ADHD

... believe that Clonicel is normalizing the excess of the adrenergic hormones that contribute to many of the symptoms of ADHD," said Horacek. Stress hormones produce a rapid heart rate, elevated blood pressure, sweating, temperature increases, heightened anxiety, stress and fear, he said. Scientists have ...

Agile Therapeutics Achieves Phase 2 Study Endpoints in Key Clinical Trials with New, Innovative Low-Dose Contraceptive Patch

... common side effects, such as breast tenderness, bloating/weight gain and nausea. These side effects are believed to be related to the level of hormones delivered into the blood stream, particularly with higher levels of estrogen. In some rare cases, high estrogen levels are thought to be linked with ...

Addrenex Pharmaceuticals' New Hires Further Company Goal to Identify New Drugs for Adrenergic Regulation

... and meet our fast-paced timelines." The indications being targeted by Addrenex are each associated with an overactive adrenergic system, a group of hormones produced by the adrenal glands that regulate the body's reaction to stress, hormonal fluctuations and myriad environmental factors. To identify new ...

Study Shows Benefits of a High Omega-3 Diet in Older Adults

... fat improves insulin sensitivity and reduces inflammatory markers, but does not alter endocrine responsiveness. This study was recently published in hormones and Metabolic Research. "As we age, hormone secretion and cell responsiveness decrease, possibly due to loss of cell membrane fluidity or ...

Soyfoods Do Not Impact Sperm Count

... Alabama at Birmingham, noted, "This study is the first to find this correlation. The research on soy in men has not found a negative impact on male hormones but rather has suggested a preventive effect in prostate cancer." Learn the facts about healthy soyfoods. Studies have indicated soyfoods may lower ...

Meditrina Pharmaceuticals, Inc. Opens Investigational New Drug (IND) Application for Phase IIb Clinical Trial With MPI-676 in Endometriosis

... reduce the amount of estrogen circulating in the body by binding to and inhibiting the enzyme aromatase, which is responsible for converting certain hormones to estrogen. In endometriosis, AIs act primarily by inhibiting local estradiol production inside the endometrial lesions. AIs are currently used for ...

New Subset Analysis of AndroGel(R) Data Highlights Efficacy - Regardless of BMI

... AndroGel was safe for men to use over the long term. Study Highlights The study presented at ENDO examined the relationship between BMI and sex hormones in hypogonadal men both before and after treatment with testosterone. The study found: -- Neither testosterone nor free testosterone is ...

Phase 3 Results for Alogliptin Demonstrated Significant Blood Sugar Reductions in Monotherapy and Four Add-on Therapy Studies

... that block the degradation of incretin hormones, GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic peptide). The incretin hormones are normally released in the digestive tract in response to food, and mediate glucose-dependent insulin secretion, accounting for over 50 percent of ...

CellCept(R) and a Reduced Level of CNI Shows Trend Towards Preservation of Kidney Function Versus a Standard-Dose CNI

... must be used simultaneously unless abstinence is the chosen method. Patients should be aware that CellCept reduces blood levels of the hormones in the oral contraceptive pill and could theoretically reduce its effectiveness. -- Severe neutropenia [absolute neutrophil count (ANC) ...

Final Results of the CellCept(R) Spare the Nephron (STN) Study Show Maintenance Therapy is Associated with Improved Renal Function

... must be used simultaneously unless abstinence is the chosen method. Patients should be aware that CellCept reduces blood levels of the hormones in the oral contraceptive pill and could theoretically reduce its effectiveness. -- Severe neutropenia [absolute neutrophil count (ANC) ...

Preventing Prostate Cancer and BPH: Prostate-Health Expert Available (National Men's Health Week Is June 9-15)

... mechanisms behind the link between obesity and the most aggressive, fatal form of prostate cancer are believed to involve both steroid hormones and systemic inflammation. "Obesity is a massive inflammatory condition," Kristal said. "It also increases levels of circulating estrogens ...

CureDM's Diabetes Therapy Achieves Major Development Milestone

... derived from a specific human gene responsible for populating the pancreas with islets, which contain the cells that secrete insulin and other hormones necessary to prevent diabetes. "Meeting this milestone has a significant impact on the commercial value of Human proIslet Peptide," according to ...

Schering-Plough Announces Imperfect Contraceptive Use Impacts Women's Emotional Well-Being

... NUVARING is not a barrier contraceptive and therefore cannot be incorrectly inserted. Upon insertion, NUVARING begins to release a steady flow of hormones and works to prevent pregnancy on a monthly basis. To prevent pregnancy for a full month, the vaginal ring must be inserted according to the ...

Help! I'm Sick. How Do I Handle My Diabetes?

... insulin or medications - Unless your health care provider tells you otherwise, continue taking insulin to balance out the battle your body's stress hormones are fighting. -- Nourish a cold - Even if you have lost your appetite, it is important to try to eat. The ADA recommends 15 grams of ...

Takeda Submits New Drug Application for Alogliptin (SYR-322) in the U.S.

... once daily. DPP-4 inhibitors are a new class of oral agents for the treatment of type 2 diabetes, which slow the inactivation of incretin hormones GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic peptide). The incretins play a major role in regulating blood ...

Video: New Results From One of the World's Largest Breast Cancer Trials Herald Hope for Thousands of Women

... of the worldwide frequency of sixteen major cancers in 1980. Int J Cancer, 1988. 41(2): p. 184-97. 4. Breastcancer.org. What role to hormones play in breast cancer treatment. Available from http://www.breastcancer.org/treatment/hormonal/what_is_it/hormone_role.jsp . (Last ...

AspenBio Pharma Reports Strong Results with Appendicitis Triage Blood Test from Large Multiple Hospital Study

... potential. The company was originally formed to produce purified proteins for diagnostic applications and has become a leading supplier of human hormones to many of the nation's largest medical diagnostic companies and research institutions. The company has successfully leveraged this foundational ...

One Year Study of Exenatide Treatment Showed Improved Beta-Cell Function

... class of agents used to treat diabetes. An incretin mimetic works to mimic the anti-diabetic or glucose-lowering actions of naturally occurring human hormones called incretins. These actions include stimulating the body's ability to produce insulin in response to elevated levels of blood sugar, inhibiting ...

One Year Study of Exenatide Treatment Showed Improved Beta-Cell Function

... class of agents used to treat diabetes. An incretin mimetic works to mimic the anti-diabetic or glucose-lowering actions of naturally occurring human hormones called incretins. These actions include stimulating the body's ability to produce insulin in response to elevated levels of blood sugar, inhibiting ...

Callisto Pharmaceuticals Completes Enrollment of Phase II Trial of Atiprimod in Neuroendocrine Cancer

... tumors, usually for less than 1 year. Carcinoid tumors typically produce a condition called "carcinoid syndrome" which is caused by the release of hormones by the tumors into the blood stream. The symptoms vary depending on which hormones are released by the tumors, but typically include diarrhea, ...

Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients

... tumors, usually for less than 1 year. Carcinoid tumors typically produce a condition called "carcinoid syndrome" which is caused by the release of hormones by the tumors into the blood stream. The symptoms vary depending on which hormones are released by the tumors, but typically include diarrhea, ...

Hollis-Eden Announces Cancellation of Acute Radiation Syndrome RFP by Department of Health and Human Services

... of a proprietary class of adrenal steroid hormones as novel pharmaceuticals for human health. ... metabolites or synthetic analogs of endogenous hormones derived by the adrenal glands from the body's most abundant circulating steroid. These steroid hormones are designed to restore the biological activity ...

Additional Data From Satraplatin SPARC Phase 3 Trial Presented at European Association of Urology Congress

... considering the fact that all these patients were progressive after hormones and chemotherapy, further suggest satraplatin's active anti-tumor effect ... treatment. Eventually, however, the tumor cells become resistant to the hormones -- or "hormone-refractory" -- and the tumor again ...
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