Idenix Pharmaceuticals Successfully Completes Proof-of-Concept Study of IDX184 for the Treatment of Hepatitis C Virus (HCV)
... of direct-acting antivirals for the treatment of
hepatitis C."
The company plans to report the ... focus is on the treatment of infections caused by
hepatitis C virus. For further information about Idenix, ... programs or commercialization activities in
hepatitis C, or any potential pipeline candidates, ...
New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients
... received a vaccine.
Reactivation of
hepatitis B virus has been reported in patients who are ... if you know or think you may be a carrier of
hepatitis B virus or if you experience signs of
hepatitis B infection, such as:
feel ...
Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis
... received a vaccine.
Reactivation of
hepatitis B virus has been reported in patients who are ... if you know or think you may be a carrier of
hepatitis B virus or if you experience signs of
hepatitis B infection, such as:
feel ...
Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting
... studies address key questions in the treatment of
hepatitis C
COPENHAGEN, Denmark, April 27 ... studies address longstanding questions in the
hepatitis C research community and provide important ... are constantly looking for ways to improve
hepatitis C treatment outcomes by increasing response rates ...
Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen
... potency in reducing viral load in patients with
hepatitis C -
NUTLEY, N.J., BRISBANE, Calif., and ... of patients chronically infected with the
hepatitis C virus (HCV)(1). The study combined two oral ...
"These are exciting times in our fight against
hepatitis C, and the investigation of the innovative oral ...
Human Genome Sciences Reports Positive Late-Breaker Results at EASL from ACHIEVE Phase 3 Trials of Albuferon(R) in Patients with Chronic Hepatitis C
... in the treatment of patients with chronic
hepatitis C. The Phase 3 results were the subject of two ... could become a leading treatment for chronic
hepatitis C."
The Phase 3 studies, known as ACHIEVE 1 ... of interferon-naive patients with chronic
hepatitis C. ACHIEVE 1 was conducted in patients infected ...
Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C
... in development for the treatment of chronic
hepatitis C (HCV). The trial will evaluate the dose and ... needs of a growing population of patients with
hepatitis C," said Rob Mitchell, Global Head of Roche's ... being held in Copenhagen, Denmark.
About
hepatitis C
...
InterMune Reports Presentation of Triple Combination Study of ITMN-191 at European Association for the Study of the Liver (EASL)
... (ribavirin) for 14 days of treatment in
hepatitis C virus (HCV) treatment-naive patients infected ... rates in patients chronically infected with the
hepatitis C virus."
Viral Kinetic Performance
... idiopathic pulmonary fibrosis (IPF) and
hepatitis C virus (HCV) infections. The pulmonology ...
ANA598 Demonstrates Potent Antiviral Activity at all Dose Levels in Completed Phase Ib Study in Hepatitis C Patients
... in which patients chronically infected with the
hepatitis C virus (HCV) were treated for three days. The ... by developing novel medicines in the areas of
hepatitis C and oncology. For the treatment of chronic
hepatitis C, the Company is developing two potentially ...
Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients
... study showed boceprevir, its investigational oral
hepatitis C protease inhibitor, in combination with ... in 595 treatment-naive patients with chronic
hepatitis C virus (HCV) genotype 1 were presented at the ... 1 is the most common and hardest to treat form of
hepatitis C.
In Part I of the study, a 48-week ...
Pharmasset Voluntarily Halts Clinical Studies with Clevudine in Hepatitis B Infected Patients
... studies of clevudine for the treatment of chronic
hepatitis B (HBV) infection.
Pharmasset recently ... receiving clevudine as prescribed therapy for
hepatitis B in South Korea. Though only a small number of ... adefovir for 96 weeks in patients with chronic
hepatitis due to infection with e-antigen ...
Pharmasset Initiates First Time in Human Study of PSI-7851 for the Treatment of Hepatitis C (HCV)
... nucleotide analog polymerase inhibitor of
hepatitis C virus (HCV). Pharmasset filed an ... of oral therapeutics for the treatment of
hepatitis B virus (HBV),
hepatitis C virus (HCV) and human immunodeficiency virus ...
FDA Approves an Expanded Indication for Peginterferon-Based Combination Therapy for Patients With Chronic Hepatitis C
... USP) combination therapy for treating chronic
hepatitis C in patients 3 years of age and older with ... the United States failed prior treatment of their
hepatitis C virus (HCV) infection, representing a large and ... therapies to meet the needs of patients with
hepatitis C."
Data from the clinical study supporting ...
Human Genome Sciences Announces Positive Results in Second of Two Phase 3 Trials of Albuferon(R) in Chronic Hepatitis C
... dosed weekly in patients with genotype 1 chronic
hepatitis C -
- Patients receiving 900-mcg Albuferon ... treatment-naive patients with genotype 1 chronic
hepatitis C (p=0.0008). Albinterferon alfa-2b is being ... become a market-leading treatment for chronic
hepatitis C."
Stefan Zeuzem, M.D., Professor of ...
Human Genome Sciences Announces Fourth-Quarter and Full-Year 2008 Financial Results and Key Developments
... first Phase 3 results for Albuferon in chronic
hepatitis C, and the data were positive. We will have ... for First of Two Phase 3 Trials in Chronic
hepatitis C Patients; Results of Second Phase 3 Trial ... patients with genotypes 2 and 3 chronic
hepatitis C. The data showed that the rate of sustained ...
Abbott and Enanta Initiate Phase 1 Clinical Trial on ABT-450 HCV Protease Inhibitor
... announced today the advancement
of their
hepatitis C (HCV) collaboration with a first-in-human ... trial in healthy volunteers.
About the
hepatitis C Virus
hepatitis C is a liver disease affecting more than 170 ...
Idenix Pharmaceuticals Initiates Proof-of-Concept Study of IDX184 for the Treatment of Hepatitis C Virus (HCV)
... The study is evaluating IDX184 in treatment-naive
hepatitis C genotype-1 infected patients.
"We are ... with the progress that we have made in our
hepatitis C discovery program in 2008, having successfully ... drugs from three major classes of direct-acting
hepatitis C antivirals in clinical development."
The ...
Human Genome Sciences Reports Substantial Progress Toward Commercialization and Announces 2009 Goals at JPMorgan Healthcare Conference
... - Albuferon(R) for
hepatitis C, LymphoStat-B(R) for lupus and ABthrax(R) for ... of Albuferon's first Phase 3 trial in chronic
hepatitis C. We will have the results of Albuferon's ... in Phase 3 Trial in Genotypes 2 and 3 Chronic
hepatitis C; Phase 3 Results in Genotype 1 Patients ...
ANA598 Demonstrates Potent Antiviral Activity in an Early Clinical Study in HCV-Infected Patients
... activity in patients infected with chronic
hepatitis C virus (HCV) in this first cohort of the study. ... by developing novel medicines in the areas of
hepatitis C and oncology. For the treatment of chronic
hepatitis C, the Company is developing two potentially ...
Pharmasset Reports Fiscal Year End 2008 Financial Results
... the potential of clevudine to treat
hepatitis B (HBV), including its
use in lamivudine ... Pharmasset made significant progress with our
hepatitis C
virus (HCV) programs. R7128, our lead HCV ... of oral
therapeutics for the treatment of
hepatitis B virus ...
Mayo Clinic Seeks New Therapies for Alcoholic Hepatitis
... ), with password: h82a7q.
Alcoholic
hepatitis is a major cause of morbidity and mortality ... "The relationship between drinking and alcoholic
hepatitis is complex. Not all heavy drinkers develop ... only moderately. Though damage from alcoholic
hepatitis often can be reversed if patients stop drinking, ...
Schering-Plough Provides Update on Boceprevir Clinical Development and Introduces Potent Next-Generation Oral HCV Protease Inhibitor for Treating Patients With Chronic Hepatitis C
... innovation leadership and long-term commitment to
hepatitis research
KENILWORTH, N.J., Nov. 24 ... on boceprevir, its lead investigational oral
hepatitis C protease inhibitor currently in Phase III ... protease inhibitor for treating chronic
hepatitis C. The company also announced that it is ...
Roche, InterMune and Pharmasset Announce Initiation of INFORM-1, the First Dual-Combination Clinical Trial with Oral Antivirals in Hepatitis C
... in patients chronically infected with the
hepatitis C virus (HCV).
The trial (run in centers in ... of oral
therapeutics for the treatment of
hepatitis B virus (HBV),
hepatitis C
virus (HCV) and human immunodeficiency virus ...
Tibotec Presents Interim Findings for TMC435, an Investigational Genotype 1 Hepatitis C Treatment, at the AASLD Liver Meeting 2008
... by Tibotec BVBA for the treatment of chronic
hepatitis C virus
(HCV) infection. Tibotec will present ... Recommendations
for Prevention and Control of
hepatitis C Virus (HCV) Infection and
HCV-Related Chronic ... the
retreatment response in patients with chronic
hepatitis C virus infection.
Liver Int. 2007 ...
Boceprevir Phase II Study Showed High Rate of Sustained Response With 28- and 48-Week Regimens in Genotype 1 Treatment-Naive Hepatitis C Patients
... showed that boceprevir, its investigational oral
hepatitis C
protease inhibitor, in combination with ... in 595 treatment-naive
patients with chronic
hepatitis C virus (HCV) genotype 1 were presented at
the ... 1 is the most common and hardest
to treat form of
hepatitis C," said Paul Kwo, M.D., associate professor ...
New Study Shows that PEGASYS(R) Regimen Provides Higher Sustained Virological Response Rates for Hepatitis C Patients
... virological response (SVR) rates for
hepatitis C patients as
compared to regimens with another ... included all
patients at our clinic who initiated
hepatitis C treatment and met basic
eligibility criteria," ... poor prognostic factors.(2)(3)(4)(5)(6)
About
hepatitis C
...
Anadys Pharmaceuticals Announces Single Dose Safety and Pharmacokinetics Results for ANA598 in Healthy Volunteers
... agonist oral prodrug, also in development
for
hepatitis C. These data strongly support the potential for ... other agents approved or under
investigation for
hepatitis C.
-- In a poster titled "Antiviral Efficacy of ... by developing novel medicines
in the areas of
hepatitis C and oncology. For the treatment of ...
Long-Term Study Evaluates Boosted PREZISTA(R) Vs. Lopinavir/Ritonavir as Part of HIV Combination Therapy in Treatment-Naive Adults
... on precautionary measures.
Drug-induced
hepatitis (e.g., acute hepatitis, cytolytic hepatitis) ... During the clinical development program
(n=3063),
hepatitis has been reported in 0.5 percent of patients ... liver
dysfunction, including chronic active
hepatitis B or C, have an increased
risk for liver function ...
Walter Reed Evaluation Concludes FirstVue(TM) HBSAG Test is Preferred over Other Rapid Tests
... evaluation,
entitled "Laboratory Evaluation of
hepatitis B Rapid Test for Use in
Screening Walking Blood ... HBSAG
test to use for screening blood donors for
hepatitis B ("HBSAG") in the
theater of war. The ... of the sensitivity of a test and
means that
hepatitis B infection can now be identified even with ...
Richard E.T. Smith, Ph.D. Joins Pharmasset as Vice President of Investor Relations and Corporate Communications
... and the investment community."
About
hepatitis C
hepatitis C is a blood-borne infectious disease of the ... 3% of
the world's population, are infected with
hepatitis C virus (HCV). The CDC
has reported that almost ...
Anadys Pharmaceuticals Announces Successful Outcome of ANA598 Healthy Volunteer Study and Finalization of Study Design for Phase Ib Trial in HCV Patients
... of ANA598 in patients chronically infected
with
hepatitis C virus (HCV). In the healthy volunteer study, ... (bid). ANA598
is the company's investigational
hepatitis C non-nucleoside polymerase
inhibitor.
Phase I ... by developing novel medicines
in the areas of
hepatitis C and oncology. For the treatment of ...
FDA Approves First Hepatitis B Viral Load Test
... HBV Test,
the first assay for quantitating
hepatitis B Virus DNA approved in the U.S.
The test uses ... application of antiviral therapy along with the
hepatitis B
vaccine has helped reduce prevalence; however,
hepatitis B remains a
serious and potentially life ...
Favourable Six Months Follow-Up Results From Intercell's Phase II Therapeutic Hepatitis C Program
... term follow up results from chronically infected
hepatitis C
patients strongly confirm and exceed positive ... long-term antiviral effect of therapeutic
hepatitis C vaccination
- Data pave the way and strongly ... clinical Phase
II study targeting treatment-naive
hepatitis C genotype-1 patients. As
previously reported in ...
Pharmasset Reports Financial Results for Quarter Ended June 30, 2008
... of clevudine for the
treatment of chronic
hepatitis B virus (HBV) infection, a $1.0 million
increase ... Agency for Research on AIDS and Viral
hepatitis (ANRS).
Anticipated Highlights
-- Announcing ... of oral
therapeutics for the treatment of
hepatitis B virus ...
Pharmasset Reports Preliminary Results of a 4-week Combination Study of R7128 for the Treatment of Chronic Hepatitis C
... patients
chronically infected with
hepatitis C virus (HCV) genotype 1. R7128, a
prodrug of ... achieved undetectable HCV RNA levels.
About
hepatitis C
hepatitis C is a blood-borne infectious disease of the ...
Top-Line Results of Boceprevir Phase II Study Showed High Rate of Sustained Response (SVR) in Genotype 1 Treatment-Naive Hepatitis C Patients
... II study of boceprevir, its investigational
oral
hepatitis C protease inhibitor. The analysis showed a high ... study of 595 treatment-nave patients with
chronic
hepatitis C virus (HCV) genotype 1.
In a 48-week ... search term boceprevir.
About
hepatitis C
...
Idenix Pharmaceuticals Advances HCV Discovery Program to Clinic
... inhibitor for the treatment of chronic
hepatitis C. Today,
Idenix also announced that is has ... are pleased with the progress we have made in our
hepatitis C
discovery program in the past few months," said ... of direct-acting antivirals for the treatment of
hepatitis C."
IDX184 Nucleotide Prodrug Polymerase ...
The New England Journal of Medicine Publishes Nexavar(R) Study Demonstrating Significant Improvement in Overall Survival in Patients With Liver Cancer
... to increase
globally, due to the prevalence of
hepatitis B and C infections," said
Jordi Bruix, ... the United States. (1,2)
In addition, chronic
hepatitis B (HBV) and C (HCV) viral infections are
the ... of Medicine, Asian Liver Center, "FAQ About
hepatitis B," February 2008. ...
Pharmasset Announces Initiation of Combination Study of Clevudine and Viread(R) for HBV by French National Agency for Research on AIDS and Viral Hepatitis (ANRS)
... Clevudine+Viread(R) in 150 patients with chronic
hepatitis B
PRINCETON, N.J., July 8 ... National
Agency for Research on AIDS and Viral
hepatitis (ANRS), with the support of
Pharmasset, Inc. ... their
combination, for the treatment of chronic
hepatitis B virus (HBV) infection
in non-cirrhotic ....
Anadys Pharmaceuticals Resumes Clinical Investigation of TLR7 Mechanism in HCV
... (TLR7) mechanism for the
treatment of chronic
hepatitis C. Based on preclinical pharmacology testing
and ... efforts in HCV. As an approach to treat
hepatitis C,
the TLR7 mechanism is independent from, and ... for 2008, Dr. Worland added,
"Because the ANA773
hepatitis C program is highly leveraged off our
oncology ...