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TWO NEW KLRI PEER-REVIEWED PUBLICATIONS: Hormone Therapy May Reduce Atherosclerosis in Women Close to Menopause; Growth Hormone May Increase Risk of Diabetes, Improve Lipid Profile in Men

... DC VA Medical Center, tests the effects of growth hormone (GH) therapy, both combined with sex ... extremely unusual to analyze the effect of both growth hormone and sex steroids," said Harman. ... studied extensively. The body naturally secretes growth hormones to ...

Is Your Hair Taking a Break?

... on the head for a shorter time due to a short growth phase, resulting in baby fine hairs that do not ... not grow new hair, it works by prolonging the growth phase of hair -- providing more time for hair to ... you want to keep that is not reaching its maximum growth and is an easy way to fill in hair density," said ...

Risks of Delaying ACL Reconstruction in Young Athletes May Be Too High, Study Shows

... under the age of 14. "The risk of inducing a growth disturbance with early reconstruction of a torn ... and fixation devices that did not cross the growth plate. Patients were also followed for a minimum of one-year post-operatively with no growth disturbances being noted. "In our study, the ...

HEALTHPOINT-Sponsored Venous Leg Ulcer Clinical Trial Enrolls First Subject for Second Phase II Study

... onto the wound surface, it is thought that growth promoting and healing signals will be generated ... and a cell preparation containing a mixture of growth arrested, living, allogeneic epidermal ... studies, HP802-247 is expected to release various growth and angiogenic factors into the microenvironment ...

CeNeRx BioPharma Obtains Rights to Novel Drug Candidate for Prevention and Treatment of Neurodegeneration Disorders

... --Orally Active Enhancer of Human Nerve growth Factor Has Demonstrated Promising Activity ... active agent that enhances the effects of nerve growth factor (NGF). CeNeRx intends to initiate a Phase ... neuropathy (CIPN) later this year. "Nerve growth factor has long been of interest as a potential ...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

... to placebo, more than doubled time without tumor growth (15.6 months vs. 5.9 months) and reduced the risk ... AUY922 exceeded the level needed to inhibit tumor growth in a mouse model for breast cancer(14). ... reduces and in many cases can control growth hormone and/or normalize IGF-1 levels in patients ...

Boehringer Ingelheim to Present New Phase II Clinical Data on Two Lead Oncology Compounds at ASCO 2009

... lung cancer (NSCLC) patients who have epidermal growth factor receptor (EGFR) mutations.(2) "Lung ... irreversible dual inhibitor of the epidermal growth factor receptor (EGFR) and human epithelial ... by simultaneously inhibiting vascular endothelial growth factor receptors (VEGFRs), ...

Spherix Reports First Quarter 2009 Earnings

... health sciences segment. Strong growth from health sciences consulting services. ... "We are pleased with the excellent growth of our health sciences consulting business," ... The Company's revenue improvement reflects the growth of its health sciences consulting services ...

Cardium Announces Completion of Patient Recruitment in Phase 2b Clinical Trial of Excellarate(TM) for the Potential Treatment of Diabetic Foot Ulcers

... locally stimulate the release of platelet-derived growth factor-B protein (PDGF-B), an important key in ... subsidiary (TRC) is focused on the development of growth factor therapeutics for the treatment of severe ... delivery carrier encoding human platelet-derived growth factor-B (PDGF-B). Excellarate(TM) is initially ...

Bayer and Regeneron Extend Development Program for VEGF Trap-Eye to Include Central Retinal Vein Occlusion

... "ischemic" (starved for oxygen), resulting in the growth of abnormal new blood vessels that can cause ... biology of CRVO is related to edema and the growth of abnormal new blood vessels that are mediated by vascular endothelial growth factor (VEGF), we are hopeful that VEGF Trap-Eye ...

Data Presented at AACR Annual Meeting Show Anti-Tumor Activity of Peregrine's Fully Human Anti-PS Antibody in Prostate Cancer Model

... Equivalent to the Human Antibody Inhibited Tumor growth in a Prostate Cancer Model by More than 90%- ... antibody of PGN635 significantly retarded the growth of tumors by more than 90%. These positive ... anti-phosphatidylserine antibody inhibits the growth of prostate cancer in mice. In: Proceedings of ...

Video: Afinitor(R) Approved in US as First Treatment for Patients With Advanced Kidney Cancer After Failure of Either Sunitinib or Sorafenib

... - Afinitor more than doubled time without tumor growth and reduced the risk of disease progression or ... controls tumor cell division and blood vessel growth - Phase III trials underway to explore ... placebo, more than doubled the time without tumor growth or death in patients with advanced kidney cancer ...

Cardium Reports on Applicability of Corgentin to Stem Cell Therapies: Independent Studies Indicate that Ad5IGF-1 Potentiates Stem Cells to Improve Cardiac Function After Heart Attack

... will lead to local production of insulin-like growth factor-1 protein to enhance this process and ... developing a portfolio of innovative DNA-based growth factor therapeutics for cardiovascular and ... subsidiary (TRC) is focused on the development of growth factor therapeutics for the treatment of severe ...

Another LNA-based RNA Inhibitor Enters Clinical Trials

... Survivin is a key protein that controls cancer growth by playing a significant role in cell division, ... SN-38 drug conjugate, markedly inhibits tumor growth and metastatic spreading of human neuroblastoma" ... specifically inhibits the growth of AR-positive tumor cells" "The antitumor ...

Healthpoint Initiates Phase II, Dose-Finding Study to Evaluate Effectiveness of a Unique Cell Based Therapy in Venous Leg Ulcers

... and a cell preparation containing a mixture of growth arrested, living, allogeneic epidermal ... studies, HP802-247 is expected to release various growth and angiogenic factors into the micro-environment ... surface in a thin fibrin matrix. The secreted growth and angiogenic factors are anticipated to ...

Cardium's InnerCool Announces Positive Benefits of Cooling During Robotic-Assisted Prostate Surgery Published in Urology

... subsidiary (TRC) is focused on the development of growth factor therapeutics for the treatment of severe ... delivery carrier encoding human platelet-derived growth factor-BB (PDGF-BB). Excellarate(TM) is ... tadenovec, Ad5FGF-4) is a DNA-based growth factor therapeutic developed for potential use by ...

American Academy Of Orthopaedic Surgeons 2009 Annual Meeting 'Highlights and Hot Topics'

... Diagnosis There is little bone growth or development after a person reaches the mid-20s ... bone and soft tissue health are now surfacing. growth factor combinations such as bone morphogenetic protein, platelet rich plasma, and platelet derived growth factor and other potential therapeutic agents are ...

Ambrx and Merck Serono Expand Collaboration Through ARX424 Multiple Sclerosis Drug Development Alliance

... in 2007 to develop ARX201, Ambrx's long-acting growth hormone product, currently in Phase II of ... ideally suited to harness the potential of our growth hormone and multiple sclerosis product candidates ... product candidate, ARX201, is a long-acting human growth hormone drug candidate partnered with Merck ...

Access Pharmaceuticals Presents new Combination Data on the Company's Angiolix(R) Therapeutic Monoclonal Antibody

... in anti-angiogenesis and significant tumor growth inhibition in MCF-7 and MX-1 breast cancer ... Lactadherin has a critical role in promoting the growth of new blood vessels to support tumor growth through the activation of VEGF-mediated ...

Modigene Announces Positive Results of Pilot Toxicity Study of Its Long-Acting Human Growth Hormone hGH-CTP

... the safety of hGH-CTP, its long-acting human growth hormone (hGH), as well as to provide preliminary ... a dose that was 1,040 times the daily dose of growth hormone recommended for use in human patients. ... proprietary long-acting version of human growth hormone. hGH is used for the long-term treatment ...

New Study First to Confirm Sandostatin LAR(R) Depot Controls Tumor Growth in Patients With Rare Gastrointestinal Tumors

... LAR more than doubled time without tumor growth for a median of 14 months compared to six months ... on findings that Sandostatin LAR halted tumor growth in 69% of patients, compared with 39% of patients ... that Sandostatin LAR also helps control tumor growth in patients with metastatic neuroendocrine tumors ...

OmegaGenesis Unveils Novel Nanotechnology Platform With Broad Biomedical Applications

... for Wounds, Diabetic Foot Ulcers and Hair growth Using Nano-Materials with Angiogenic Properties ... for wound healing, diabetic foot ulcers and hair growth are being developed by the company, with plans to ... of wound healing, diabetic foot ulcers and hair growth are underway. Clinical trials are anticipated to ...

Bayer Announces Upcoming Presentations of Campath(R) and Leukine(R) Data at the 50th Annual Meeting of the American Society of Hematology

... About Leukine Leukine is a growth factor that helps fight infection and disease in ... HealthCare Pharmaceuticals. Leukine is the only growth factor approved in the U.S. for use following ... its indications, Leukine is the only myeloid growth factor approved to reduce the incidence of ...

New Data Show In Vitro Potency of Doripenem Against Resistant Bacteria

... than imipenem and ertapenem, and inhibited growth of CIPRE and ESBLE at very low drug ... -- Doripenem, imipenem and ertapenem, inhibited growth of >90% of ESBLE at concentrations of 0.25 ... doripenem, imipenem and ertapenem inhibited the growth of >90% of CIPRE at concentrations of 0.5 ...

Millennium Presents New Data on Investigational Drugs for Novel Cancer Targets at EORTC-NCI-AACR Symposium

... Nedd8 Activating Enzyme (NAE) in tumor growth and survival. It is a first-in-class small ... Growth Factor Receptor / Human Epidermal growth Factor Receptor (EGFR/HER) and Vascular Endothelial growth Factor/Platelet ...

Quark Pharmaceuticals Announces Publication of Study on Use of siRNA against Proprietary Target for Inhibiting Tumor Growth and Sensitization of Cancer Cells to Chemotherapy

... in Non-Small Cell Lung Cancer Inhibits Tumor growth and Increases Efficacy of Chemotherapy," reports ... Suppression of Nrf2 effectively inhibited tumor growth and increased sensitivity to chemotherapeutic ... of therapeutics that target Nrf2 to inhibit tumor growth and circumvent chemoresistance." Quark ...

Protein Shown to Play a Key Role in Normal Development of Nervous System

... for the neurotransmitter glutamate, promotes the growth of dendrites, both in nerve cell cultures and in ... signals into the cell. The most vigorous dendrite growth occurs shortly after birth, when GluR1 is present ... with another protein, SAP97, to control dendrite growth during the early postnatal period. "Our ...

Uroplasty Enrolls First Patients in Urgent(R) PC Clinical Trial

... we have seen a moderation in our U.S. sales growth during the second fiscal quarter ending September 30. While we still expect solid U.S. sales growth over the previous fiscal year, we do not expect to reach the sales growth forecast we have provided for the fiscal year. We ...

Eating Walnuts Slows Cancer Growth, Laboratory Study Finds

... -- Snack-sized quantities of walnuts slow cancer growth in mice, reports a Marshall University ... diet. "When we fed the mice the walnuts, the growth rate of the tumors they had was dramatically ... very good to find something that will slow the growth of tumors without being toxic chemotherapy," said ...

Encorium Announces the Initiation of a Strategic Partnership With Prologue Research After the Postponement of Negotiations Regarding Its Planned Acquisition; Strategic Reorganization and Cost Reduction Plan Initiated as Strategic Alternatives are Investig

... its management energies on intracompany sales growth as well. The Company also announced that it has ... Europe, continue to provide significant growth opportunities," commented Dr. David Ginsberg, the ... countries. We also intend to expand and focus our growth efforts in additional therapeutic areas as well. ...

Latest RAD001 Study Results Show Further Increase in Time Without Tumor Growth in Patients With Advanced Kidney Cancer

... data, updated since ASCO, show time without tumor growth now reaches nearly 5 months with RAD001 ... show that patients receiving RAD001 had no tumor growth for nearly 5 months vs. 1.9 months for patients ... of patients and societies. Focused solely on growth areas in healthcare, Novartis offers ...

RAD001 Combined with Sandostatin LAR(R) Depot and as Monotherapy Controls Growth of Rare Pancreatic Neuroendocrine Tumors

... suspension) and RAD001 given alone control tumor growth in patients with pancreatic neuroendocrine ... even more potent than somatostatin at inhibiting growth hormone, glucagon and insulin. Based on these ... of patients and societies. Focused solely on growth areas in healthcare, Novartis offers ...

RAD001 Granted Priority Review in the US Based on Potential to Fill Unmet Medical Need in Patients With Advanced Kidney Cancer

... that RAD001 more than doubles time without tumor growth and reduced risk of disease progression by ... RAD001 more than doubled time without tumor growth and reduced the risk of disease progression ... of patients and societies. Focused solely on growth areas in healthcare, Novartis offers ...

Cardium Reports on Second Quarter 2008 Highlights and Financial Results

... Ad5FGF-4), is a DNA-based growth factor therapeutic being developed for potential ... a one-time treatment to promote and stimulate the growth of collateral circulation in the hearts of ... company focused on the development of growth factor therapeutics for the treatment of severe ...

Cardium Announces Appointment of Paul A. Foster, M.D. to Lead Generx and Excellarate Late-Stage Development Activities

... Ad5FGF4), is a DNA-based growth factor therapeutic being developed for potential ... a one-time treatment to promote and stimulate the growth of collateral circulation in the hearts of ... company focused on the development of growth factor therapeutics for the treatment of severe ...

Taligen Therapeutics Initiates Corporate Growth Plan with Appointment of Abbie Celniker, Ph.D., as CEO and Establishment of Cambridge, Mass., Headquarters

... Inc. today announced it has initiated a corporate growth plan with the appointment of Abbie Celniker, ... to working with her as we implement our corporate growth plan to build a company focused on ... is expected to enable Taligen to implement its growth plan and advance multiple product candidates to ...

Halozyme Therapeutics Announces Positive Findings With Pegylated Enzyme in Prostate Cancer Models

... Xenograft PC3 results -- Tumor volume growth suppressed significantly. Tumor volume ... Xenograft Du145luc results -- Tumor volume growth unaffected by combination treatment, as expected. ... unlike the HA-producing PC3 tumors, tumor growth curves in the control and the PEGPH20 groups were ...

Modigene Platform Validated in Independent Phase III Trial of CTP Technology

... to extend the duration of action of human growth hormone and interferon beta, with the goal of ... of Modigene's CTP-enhanced versions of human growth hormone and interferon beta that we intend to ... fertility trial ever conducted. Human growth hormone (hGH), which is used to ...

Kansas Invests Millions in Innovations to Improve Human Health and Launches Three National Bioscience Programs at BIO'08

... are finding tremendous opportunities for growth in Kansas," Smilor said. "It's not just the ... initiative created by the Kansas Economic growth Act of 2004 to expand the state's ... capacity and bioscience clusters; support the growth of bioscience startups; and stimulate bioscience ...

Bionovo Elucidates Mechanism of Breast Cancer Control by Estrogen Receptor Beta

... role of estrogen receptor beta in breast cancer growth regulation. The data, which were presented at the ... gene via the estrogen receptor beta results in growth arrest. "Breast cancer is the most common ... activation of important genes that stimulate the growth of cancer cells. This pathway might be an ...
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(Date:4/23/2014)... of Toronto Scarborough research shows that male black widow ... a rare example of mate preference by male ... post-doc Emily MacLeod and Maydianne Andrade, a professor in ... field studies and the wild that males overwhelmingly chose ... male black widows can tell whether a potential mate ...
(Date:4/23/2014)... TX (4/23/14) -- Researchers have found evidence of ... factors that increase aggressive behavior in children, especially ... not all children exposed to prenatal smoking will ... will not," said Brian Boutwell, Assistant Professor at ... and senior author on the study. "One ...
(Date:4/23/2014)... today announced Sophie Martin of the University of Lausanne, ... Medal. The award acknowledges her work to understand the ... the cell. , Martin has been working for the ... the way in which the spatial organization of cells ... last 11 years, she has been using fission yeast, ...
Breaking Biology News(10 mins):Picky male black widow spiders prefer well-fed virgins 2Genetics risk, prenatal smoking may predict behavioral problems 2EMBO Gold Medal 2014 awarded to Sophie Martin 2
(Date:4/24/2014)... the corresponding terminology, and the relevance of palliation ... publications on randomized controlled trials (RCTs). This is ... Institute for Quality and Efficiency in Health Care ... report. , Together with external experts, IQWiG analysed ... lung cancer, malignant melanoma, and pancreatic cancer. For ...
(Date:4/24/2014)... 4/24/14) Dartmouth has been awarded one of 30 ... as a Lead Academic Participating Site in its new ... recipients are a select groups of investigators charged with ... cooperative groups., The NCTN grant system reflects recommendations from ... streamlines operations to achieve four goals:, Faster ...
(Date:4/23/2014)... A pilot study by Massachusetts General Hospital (MGH) investigators ... unusual treatment for a serious medical problem use ... diarrhea caused by the Clostridium difficile ( ... published online in the journal Clinical Infectious Diseases ... fecal material from donors unrelated to patients was as ...
(Date:4/23/2014)... O,Shea, M.D., scientific director at the National Institute of ... named the 2014 recipient of the Ross Prize in ... journal Molecular Medicine . The award will be ... of Sciences in Manhattan, followed by scientific presentations by ... of the National Institutes of Health. , The award, ...
(Date:4/23/2014)... an important enzyme pathway that helps prevent new cells ... condition that has been directly linked to cancer and ... found that near the end of cell division, the ... breaks in DNA are fully repaired before the parent ... This process helps safeguard against some of the most ...
Breaking Medicine News(10 mins):Health News:Palliation is rarely a topic in studies on advanced cancer 2Health News:Palliation is rarely a topic in studies on advanced cancer 3Health News:Dartmouth awarded lead role in NCI clinical trials network 2Health News:Dartmouth awarded lead role in NCI clinical trials network 3Health News:Use of frozen material for fecal transplant successfully treats C. difficile infection 2Health News:Use of frozen material for fecal transplant successfully treats C. difficile infection 3Health News:NIH scientist to receive Ross Prize in Molecular Medicine 2Health News:Study identifies enzymes that help fix cancer-causing DNA defects 2
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