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Pharmasset Reports Positive Preliminary Antiviral Data With PSI-7851 for the Treatment of Hepatitis C

... of hepatitis C (HCV). PSI-7851 is a second generation nucleotide polymerase inhibitor of HCV. ... and safety data with PSI-7851, our second generation nucleotide analog," said Michelle Berrey, MD, ... 15-fold more potent than Pharmasset's first generation nucleoside polymerase inhibitor, RG7128 (formerly ...

VivoMetrics(R) Introduces Next Generation LifeShirt Prototype, a Smart Garment That Delivers Real-time Vital Signs Remotely to Healthcare Providers

... today the first complete prototype of their next generation LifeShirt for the remote monitoring of patients' ... realization of telemedicine. The next generation LifeShirt incorporates cutting-edge sensor ... intent is to address these needs with the next generation LifeShirt and help make the full promise of RPM a ...

CardioVascularCS.Org, a division of EndoVascular Forum, Inc., Partners with Complex Interventional Cardiovascular Therapy (CICT) to Extend Electronic Medical Care Advancement

... Forum's commitment to developing a new generation of tools for physicians to learn from peer ... a complementary, accelerated path to knowledge generation and dissemination. "The end goal of this ... ( www.ICSciences.com ). The EVF NGHI (next generation health Internet) community comes together to ...

PharmAthene Submits SparVax(TM) Regulatory Strategy to FDA

... plans for licensure of SparVax(TM), a next generation recombinant protective antigen anthrax vaccine. ... to develop and procure 25 million doses of a next generation rPA anthrax vaccine for the country's civilian ... the advanced development and procurement of next generation rPA anthrax vaccines." About SparVax(TM) ...

Pharmasset Initiates First Time in Human Study of PSI-7851 for the Treatment of Hepatitis C (HCV)

... in healthy volunteers with PSI-7851, a second generation nucleotide analog polymerase inhibitor of ... Pharmasset. PSI-7851 is a wholly owned, second generation nucleotide analog that was discovered by ... than the active metabolite of Pharmasset's first generation nucleoside polymerase inhibitor, R7128. In vitro ...

Sangamo BioSciences Provides Update on Company's 2008 Progress and 2009 Objectives

... our technology platform, which is unique in its generation of novel, highly differentiated therapies and ... establishing the utility of ZFNs in the generation of transgenic animals and the potential ... ZFN technology as a new approach for rapid generation of "knock-out" cell lines (Santiago et al., 2008, ...

Stem Cell Sciences Announces the Creation of the World's First Authentic Rat Embryonic Stem Cells from its Exclusively Licensed Technology

... important new technology is that it allows the generation of both knock-out rat models, in which the effect of gene deletion is studied, as well as the generation of knock-in models, which involves the insertion ... "This remarkable breakthrough will enable the generation of transgenic rat models for drug discovery in a ...

Ardea Biosciences Appoints John W. Beck Chief Financial Officer, Announces Clinical Development Progress and Reports First Quarter 2008 Financial Results

... a first-in-human micro-dosing study of our second generation NNRTI, RDEA427, and selected it as a ... a first-in-human micro-dosing study of our second generation MEK inhibitor, RDEA436, and selected it as a ... favorable resistance profiles for our next generation NNRTI family of compounds against HIV at the ...

Sangamo BioSciences and Sigma-Aldrich Announce Publication of Study Demonstrating Zinc Finger Technology for Rapid Generation of 'Knock-Out' Cell Lines

... nucleases (ZFNs(TM)) in a new approach for rapid generation of "knock-out" cell lines, important tools in ... advance in the specificity and efficiency of the generation of cell lines in which an individual gene ... vice president of research. "The generation of knockouts in basic research and industrial ...

Poniard Pharmaceuticals Provides Year-End Clinical Update at 2007 Lazard Capital Markets Healthcare Conference

... to advance our development of picoplatin, a new generation chemotherapy agent with the potential to become a ... . About Picoplatin Picoplatin is a new generation platinum chemotherapy agent with the potential to ... lead platform product candidate, is a new generation platinum therapy with an improved safety profile. ...

Sangamo BioSciences and Sigma-Aldrich Announce Nature Biotechnology Study Demonstrating Zinc Finger Technology for Modification of Human Stem Cells

... in stem cells potentially enabling the efficient generation of stem cell lines for use as models of human ... for drug testing. In addition to its use in the generation of valuable research reagents, the technology has ... has revolutionized biology and enabled the generation of mouse cell-lines and transgenic mouse models ...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... modified animal models of human disease. ZFN technology will make the generation of such animals faster and will create new opportunities in species other ... transgenic rats using DNA or lentiviral vector microinjection. The generation of transgenic rats also is open to the scientific community through an ...

Poniard Pharmaceuticals Announces Positive Cardiac Safety Data From Picoplatin Phase 1 Trial Supporting NDA Filing

... announced results from a Phase 1 cardiac safety study of picoplatin, a new generation platinum-based chemotherapy agent and the Company's lead product ... later this year. About Picoplatin Picoplatin is a new generation platinum-based chemotherapy agent that is in clinical development for ...

Thiarabine Demonstrates a Reduction of Both Inflammatory and Erosive Disease Parameters in Rheumatoid Arthritis

... be developed for rheumatoid arthritis as well." Thiarabine is a next generation nucleoside analogue that Access has licensed from Southern Research. It ... factor and is targeted to breast cancer; and Thiarabine , a new generation nucleoside analog which has demonstrated both pre-clinical and clinical ...

Sangamo BioSciences Announces Achievement of Key Milestone in Cell Engineering Agreement With Genentech

... with Genentech, Inc., a wholly-owned member of the Roche Group, for the generation of cell lines with novel characteristics for pharmaceutical protein ... obviates the need for selection markers, thereby enabling the rapid generation of cell lines in which multiple genes have been knocked out. Our proven ...

Trius Announces Positive Results From Phase 2 Clinical Trial of Torezolid in Patients With Complicated Skin and Skin Structure Infections

... Second generation Oxazolidinone Demonstrates Safety and Efficacy with Once-Daily, 200 ... pathogens. The company's lead drug candidate, torezolid, is a second generation oral and IV oxazolidinone antibiotic with potent activity against ...

Access Pharmaceuticals Announces Publication of Thiarabine Combination Data

... for download from the journal's website. "Thiarabine is a next generation nucleoside analogue, licensed by Access from Southern Research Institute ... factor and is targeted to breast cancer. Thiarabine is a new generation nucleoside analog which has demonstrated both pre-clinical and clinical ...

PharmAthene Submits Proposal to BARDA in Response to Broad Agency Announcement for Advanced Research and Development for Valortim(R)

... development programs include: SparVax(TM) - a second generation recombinant protective antigen (rPA) anthrax vaccine Valortim(R) - ... RypVax(TM) - a recombinant dual antigen vaccine for plague A third generation rPA anthrax vaccine. For more information about ...

First Jatropha Genome Completed by Synthetic Genomics Inc. and Asiatic Centre for Genome Technology

... it can be grown on marginal, non-food producing lands; has a very short generation time; can be productive for 30 to 40 years; and its seed oil and biomass ... of the genome, using both traditional Sanger sequencing and next generation sequencing, has revealed that the jatropha genome is approximately 400 ...

BioVex to Report Phase I/II Clinical Trial Results for the Front Line Treatment of Head and Neck Cancer With OncoVEX GM-CSF at the 2009 American Society of Clinical Oncology Meeting

... Mass., May 15 /PRNewswire/ -- BioVex Inc, a company developing next generation biologics for the treatment and prevention of cancer and infectious ... recently commenced a Phase III study in metastatic melanoma following the generation of an unprecedented number of durable complete remissions in a Phase II ...

PharmAthene to Host a Conference Call and Webcast on Wednesday, April 29th at 4:30 PM to Provide an Update on the SparVax(TM) rPA Anthrax Vaccine Program

... development programs include: SparVax(TM) - a second generation recombinant protective antigen (rPA) anthrax vaccine Third generation rPA anthrax vaccine Valortim(R) - a fully human monoclonal ...

Facet Solutions, Inc. Expands U.S. Pivotal Study With Next Generation Implant System

... Study for the treatment of lumbar spinal stenosis utilizes the second generation design technology from Facet Solutions, Inc. This technology enables the ... stability to the lumbar spine. Average implantation times with the second generation design are equivalent to implantation times for standard postero-lateral ...

Pharmasset Voluntarily Halts Clinical Studies with Clevudine in Hepatitis B Infected Patients

... trial at the upcoming EASL meeting. Pharmasset's unpartnered second generation HCV nucleoside, PSI-7851, is progressing well in a phase I trial and we ... has completed a Phase 2 clinical trial. PSI-7851, an unpartnered second generation HCV nucleotide analogue recently entered phase 1 studies. Pegasys(R) ...

AACR Data Highlights InNexus Preclinical Antibody Candidate

... ), a drug development company commercializing the next generation of monoclonal antibodies based on its technology, Dynamic Cross Linking ... InNexus is a drug development company commercializing the next generation of monoclonal antibodies based on its DXL technology, which improves the ...

Study Data Show Positive European Experience With DuraHeart Left Ventricular Assist Device for Advanced Stage Heart Failure Patients

... rates during DuraHeart support were acceptable in comparison to first generation pulsatile and second generation axial flow LVADs. The event rate of bleeding requiring surgery (0.22 per ...

Novel Valortim(R) Mechanism of Action Data Presented at the Keystone Symposia on Molecular and Cellular Biology

... development programs include: SparVax(TM) - a second generation recombinant protective antigen (rPA) anthrax vaccine Valortim(R) - ... RypVax(TM) - a recombinant dual antigen vaccine for plague A third generation rPA anthrax vaccine. For more information about ...

DSM Obtains Exclusive World-Wide License for Innovative Drug Delivery Technology

... platform, this will open up a broad range of opportunities for next generation drug delivery. DSM's activities in this field are a perfect illustration ... technology for the delivery of biologics and drugs is based on a next generation set of polymers exclusively licensed from Cornell University . Generated ...

Research Teams at J. Craig Venter Institute and Ludwig Institute for Cancer Research Uncover New Chromosomal Alterations in Cancer Using Transcriptome Sequencing Approach

... changes in certain cells. Continued advances and cost efficiencies of next generation DNA sequencing technologies are enabling this more precise and detailed ... in cancer. The team concluded that transcriptome sequencing with next generation sequencing technologies such as the 454 Life Sciences platform is very ...

Trius Completes Enrollment in Phase 2 Clinical Trial Evaluating Torezolid (TR-701) in Patients With Complicated Skin and Skin Structure Infections

... 180 Patient Trial of 2nd generation Oxazolidinone Enrolls in Four Months SAN DIEGO, Jan. 26 /PRNewswire/ ... pathogens. The company's lead drug candidate, torezolid, is a second generation oral and IV oxazolidinone antibiotic with potent activity against ...

Gene Therapy Corrects Sickle Cell Disease in Laboratory Study

... altered blood-forming cells from the original treated mice into a second generation of sickle cell mice to show that the gamma-globin gene had incorporated ... blood-forming cells. Five months after that transplantation, the second generation of mice also showed production of fetal hemoglobin and correction of their ...

The Government of Canada Procures IMVAMUNE(R) Smallpox Vaccine for the Country's Biological Preparedness

... for Proposal issued in 2007 with the intent to procure an MVA-based, third generation smallpox vaccine, Public Works and Government Services Canada, on behalf ... 25 % of the population. IMVAMUNE(R), Bavarian Nordic's new, third generation smallpox vaccine, offers a number of unique advantages compared to the old ...

PharmAthene Initiates Phase I Clinical Trial of Nerve Agent Bioscavenger Protexia(R)

... lead product development programs include: -- SparVax(TM) - a second generation recombinant protective antigen (rPA) anthrax vaccine -- Third generation rPA anthrax vaccine -- Valortim(R) - a fully human monoclonal antibody ...

Texas Cardiac Arrhythmia Institute at St. David's Medical Center Selected to Conduct Clinical Trial for Device to Treat Atrial Fibrillation

... the pathway for the abnormal heart rhythm. The new study involves second generation software (Gen II) that uses a catheter believed to result in the formation ... temperature at the catheter's tip, overheating may occur, resulting in the generation of a less effective lesion. "While many studies involve less complex ...

PharmAthene Presents Data for Protexia(R) and Valortim(R) at 2008 BARDA Industry Conference / PHEMCE Stakeholders Workshop

... lead product development programs include: -- SparVax(TM) -- a second generation recombinant protective antigen (rPA) anthrax vaccine -- Third generation rPA anthrax vaccine -- Valortim(R) -- a fully human monoclonal antibody ...

Southern Research Institute Wins $14.7 Million NIH Award to Participate in Molecular Libraries Probe Production Center Network

... Libraries Program (MLP) is a full-scale production program emphasizing the generation of high quality probes and biological-chemical data for high-value ... abilities that will enable screening of diverse types of assays and generation of chemical probes to address a wide range of biological opportunities. ...

febit and TGen Collaborate to Study New DNA Capture Method

... conversation on the future direction of genomic research centers on next generation sequencing," said Matthew Huentelman, Ph.D., TGen associate investigator ... for TGen researchers to make a difference in research utilizing next generation sequencing." TGen has been a user of the Geniom One device for the ...

First DuraHeart(TM) Left Ventricular Assist System Implanted in the U.S. Pivotal Trial

... readily available for the increasing need of heart failure patients. Third generation systems are anticipated to demonstrate improved outcomes and long term reliability. DuraHeart is the most advanced third generation centrifugal pump by virtue of the magnetically levitated impeller, ...

New CyberKnife Technologies Demonstrate Dramatic Reduction in Treatment Times

... First Patients Treated Using Next generation CyberKnife System at Oklahoma CyberKnife Center ... Oklahoma CyberKnife, LLC purchased its CyberKnife System with all the next generation upgrades included, those same upgrades were made available to existing ...

Aegera Initiates a Fifth Phase 1 and 2 Clinical Trial for AEG35156

... in a fifth phase 1 and 2 clinical oncology study of AEG35156, a second generation antisense therapeutic targeting XIAP, a key member of the Inhibitor of ... disable their normal response to apoptotic triggers. AEG35156, a second generation antisense which targets XIAP, is designed to lower the apoptotic threshold ...

Start of Phase I Study for Intranasal Pandemic Influenza Vaccine deltaFLU

... its intranasal vaccine deltaFLU against pandemic influenza. This novel generation of a live-attenuated vaccine based on the deletion of the NS1 gene has ... has optimized the method of reverse genetics, which permits the generation of a vaccine against any potential influenza virus within a very short ...
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(Date:7/31/2014)... the National Science Foundation (NSF), counters a widely-held ... warming, indicating instead that certain Arctic lakes store ... atmosphere. , The study, published this week ... thermokarst lakes, which occur as permafrost thaws and ... water, converting what was previously frozen land into ...
(Date:7/31/2014)... that biomass burning burning forests to create ... slash-and-burn agriculture and wildfires figures into both ... the release of a new study by Stanford ... Jacobson, the degree of that contribution had never ... a paper published July 30 in the ...
(Date:7/31/2014)... hidden hazard lurks beneath many of the roughly ... The hazard is corrosion in parts of underground ... leaks and contamination of groundwater, a source of ... nine states have reported many rapidly corroding gas ... incidents are generally associated with use of gasoline-ethanol ...
Breaking Biology News(10 mins):Certain Arctic lakes store more greenhouse gases than they release 2Stanford professor finds that wildfires and other burns play bigger role in climate change 2Stanford professor finds that wildfires and other burns play bigger role in climate change 3Stanford professor finds that wildfires and other burns play bigger role in climate change 4NIST corrosion lab tests suggest need for underground gas tank retrofits 2
(Date:8/1/2014)... August 01, 2014 Stryker hip ... of the 2012 Rejuvenate and ABG II Modular-Neck ... New Jersey’s Bergen County Superior Court, Bernstein Liebhard ... proceeding, the Court has issued a Final ... and all hard copy and electronic materials produced ...
(Date:8/1/2014)... August 01, 2014 Summer is here, and ... active during the summer, and they can be a pain ... ready to help all their customers get rid of ticks ... and 6,000 eggs in the summer, which is why they ... in tall grass and woodland areas and carry a number ...
(Date:8/1/2014)... Washington, DC (PRWEB) August 01, 2014 ... Mike Thompson (D-CA), Gregg Harper (R-MS), and Peter ... H.R. 5380, the Medicare Telehealth Parity Act of ... "We fully support this effort to improve healthcare ... Linkous, chief executive officer of ATA. "These cost-saving ...
(Date:8/1/2014)... The "Antimicrobial Coatings Market by Type (Silver, ... Dioxide, and Zinc Omadine), Application (Indoor air/HVAC, Medical, ... Textiles, and others), & Geography (North America, Europe, ... to 2018" analyzes the Antimicrobial Coatings Market with ... the diverse geographical regions. , Browse 49 market ...
(Date:8/1/2014)... The North America Endpoint Security Market report defines ... America with analysis and forecast of revenue. This market ... 2014 to $4.77 billion by 2019, at a CAGR ... the TOC of the North America Endpoint Security Market ... provided. It also provides a glimpse of the segmentation ...
Breaking Medicine News(10 mins):Health News:Stryker Hip Lawsuit News: New Order Issued in New Jersey Stryker Hip Recall Litigation, Bernstein Liebhard LLP Reports 2Health News:Stryker Hip Lawsuit News: New Order Issued in New Jersey Stryker Hip Recall Litigation, Bernstein Liebhard LLP Reports 3Health News:Tis the Season for Tick Prevention 2Health News:ATA Applauds Bill on Medicare Telemedicine Improvements 2Health News:Antimicrobial Coatings Market Projected to Reach $2.9 Billion by 2018 – Report by MarketsandMarkets 2Health News:Antimicrobial Coatings Market Projected to Reach $2.9 Billion by 2018 – Report by MarketsandMarkets 3Health News:Antimicrobial Coatings Market Projected to Reach $2.9 Billion by 2018 – Report by MarketsandMarkets 4Health News:North America End-Point Security Market is Expected to Reach $4 billion in 2019 - New Report by MicroMarket Monitor 2Health News:North America End-Point Security Market is Expected to Reach $4 billion in 2019 - New Report by MicroMarket Monitor 3Health News:North America End-Point Security Market is Expected to Reach $4 billion in 2019 - New Report by MicroMarket Monitor 4
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