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Fungal in Medical Technology

Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)

... prior to CIMZIA use. Invasive fungal infections, including histoplasmosis, ... Patients with histoplasmosis or other invasive fungal infections may present with disseminated, rather ... be considered in patients at risk for invasive fungal infections who develop severe systemic illness. ...

MacroChem Announces Phase 2 Data for EcoNail(R) in the Treatment of Onychomycosis

... cure" defined as negative mycology (negative fungal culture and negative KOH) and clear nail (as ... to 25%) clinical improvement. All patients had fungal culture-proven nail infections at entry, but ... progressive clinical improvement and reduction of fungal disease burden. Based on the practical definition ...

Prospective Microbial Analysis of Bronchoalveolar Lavage Fluids with Immune Function Testing Can Distinguish Between Fungal Colonization and Fungal Disease In Lung Transplant Recipients

... and those patients with active fungal infections. These data were presented in an oral ... of CMI, would be different for patients with fungal colonization as compared to patients with true ... are significantly different for patients with fungal colonization as compared to patients with ...

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... Serious infections, including sepsis, pneumonia, tuberculosis, invasive fungal and other opportunistic infections have been observed with the use of TNF ... For patients who have resided in or traveled to regions where invasive fungal infections such as histoplasmosis, coccidioidomycosis, or blastomycosis ...

Lytix Presents LTX-109 Anti-Microbial Data at ICAAC

... we could now consider it for other indications such as skin and nail fungal infections, acne and oropharyngeal candidaisis. We are now in the final ... AS develops novel drugs for the treatment of resistant bacterial and fungal infections, as well as first-in-class oncology treatments. Lytix was ...

Durezol(TM) in the Treatment of Uveitis and Ganciclovir in the Treatment of Herpetic Keratitis: Studies of Treatments for Leading Causes of Blindness to Be Presented

... patients with viral diseases of the cornea and conjunctiva, and those with fungal or mycobacterial infections of the eye or ocular structures. Prolonged use ... the severity of ocular viral infections, and increase the development of fungal infections of the cornea. It is important to monitor intraocular pressure ...

Sirion Therapeutics Announces Positive Pivotal Uveitis Data for Durezol(TM)

... patients with viral diseases of the cornea and conjunctiva, and those with fungal or mycobacterial infections of the eye or ocular structures. Prolonged use ... the severity of ocular viral infections, and increase the development of fungal infections of the cornea. It is important to monitor intraocular pressure ...

Independent Studies Report on Possible Roles for Cylex's Immune Cell Function Assay in Monitoring of Heart and Lung Transplant Recipients

... April 10 -- "Use of an immune monitoring assay to distinguish between fungal colonization and fungal disease in lung transplant recipients" (S. Husain, J. Pilewski, K. ...

Immtech Focusing on Other Infectious Disease Programs Following Discontinuation of Development of Pafuramidine

... discovery programs targeting Hepatitis C, and drug-resistant bacterial and fungal infections, and will discontinue all development programs for pafuramidine ... compounds targeting Hepatitis C, drug- resistant Gram-positive bacteria, fungal infections and other serious diseases. It is expanding its targeted ...

Immtech Receives $5.1 Million to Further African Sleeping Sickness Clinical Trials

... is also in a pivotal Phase III trial for pneumocystis pneumonia (PCP), a fungal infection in the lungs that can affect people living with HIV/AIDS and ... library of compounds targeting drug-resistant Gram-positive bacteria, fungal infections, Hepatitis C and other serious diseases. Immtech holds the ...

Chinese SFDA Grants Immtech Fast Track Status

... to combat PCP and other devastating infectious diseases." PCP is a fungal infection in the lungs and can cause potentially life-threatening ... and a well defined, expanding library of compounds targeting Hepatitis C, fungal infections, and bacterial infections. Immtech holds exclusive worldwide ...

New Data From Large Safety Analysis of MYCAMINE Shows Favorable Clinical Safety Profile

... activity, demonstrating its value as an effective treatment for invasive fungal infections, compared to other drugs in its class. "Astellas has a history ... agents, the echinocandins. MYCAMINE inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Important ...

Schering-Plough Announces U.S. Filing of Mometasone Furoate/Formoterol Fumarate Combination for the Maintenance Treatment of Asthma

... reactions, facial swelling, hives, and throat tightness reported. Patients who use inhaled steroid medicines for asthma may develop a fungal infection of the mouth and throat. Rinse your mouth after using ASMANEX. It is possible that hypercorticism (an excess level of steroids in ...

FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent

... doctor about all of your medical conditions, including kidney problems. Also, tell your doctor about all medicines you take, including those to treat fungal infections, cyclosporine, potassium-containing medicines, potassium supplements, or salt substitutes containing potassium. Additionally, if you take ...

ASMANEX(R) (Mometasone Furoate Dry Powder Inhaler) Now Approved in Japan for the Treatment of Bronchial Asthma in Adult Patients

... allergic reactions, facial swelling, hives, and throat tightness reported. Patients who use inhaled steroid medicines for asthma may develop a fungal infection of the mouth and throat. Rinse your mouth after using ASMANEX. It is possible that hypercorticism (an excess level of steroids in your ...

New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients

... with TB. Tell your doctor if you have been in a region (such as the Ohio and Mississippi River Valleys and the Southwest) where certain fungal infections like histoplasmosis or coccidioidomycosis are common. You should not start SIMPONI(TM) if you have any kind of infection. Tell ...

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

... with TB. Tell your doctor if you have been in a region (such as the Ohio and Mississippi River Valleys and the Southwest) where certain fungal infections like histoplasmosis or coccidioidomycosis are common. You should not start SIMPONI(TM) if you have any kind of infection. Tell ...

Afinitor(R) Phase II Data Show Positive Results for Patients With Multiple Types of Lymphoma, Leading to Phase III Trial

... In addition, non-infectious pneumonitis may require temporary dose reduction and/or interruption or discontinuation. Patients with systemic invasive fungal infections should not receive Afinitor. Oral ulceration is a common side effect with Afinitor. Renal function, blood glucose, lipids and ...

New One-Year Data from REMICADE(R) SONIC Trial Show Sustained Efficacy Compared with Azathioprine in Treatment of Crohn's Disease

... with a skin test. If a patient has latent (inactive) TB, TB treatment should begin before starting REMICADE. Lived in a region where certain fungal infections like histoplasmosis or coccidioidomycosis are common. An infection that keeps coming back (or any problems that increase the risk ...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

... In addition, non-infectious pneumonitis may require temporary dose reduction and/or interruption or discontinuation. Patients with systemic invasive fungal infections should not receive Afinitor. Oral ulceration is a common side effect with Afinitor. Renal function, blood glucose, lipids and ...

First Jatropha Genome Completed by Synthetic Genomics Inc. and Asiatic Centre for Genome Technology

... microbial life around the jatropha tree using environmental genomic techniques to sequence and analyze jatropha's root, soil and leaf bacterial and fungal communities. By understanding these environments SGI and ACGT will be able to develop diagnostic tests for plant diseases and agents for disease ...

Video: Afinitor(R) Approved in US as First Treatment for Patients With Advanced Kidney Cancer After Failure of Either Sunitinib or Sorafenib

... In addition, non-infectious pneumonitis may require temporary dose reduction and/or interruption or discontinuation. Patients with systemic invasive fungal infections should not receive Afinitor. Oral ulceration is a common side effect with Afinitor. Renal function, blood glucose, lipids and ...

NovaBay Pharmaceuticals Announces Lead Anti-infective Product Candidate, NVC-422, Shown to be Effective in Treating Topical Fungal Infection

... including onychomycosis, tinea pedis, and tinea capitis. Importantly, these data provide strong support for continuing to develop NVC-422 for fungal infections." NVC-422 is the most advanced of a series of compounds from a new class of drugs that mimics the body's natural defense against ...

Galderma Announces Interim Data Relating to Sequential Treatment Regimen of Clobex(R) Spray Followed by Vectical(TM) Ointment in Managing Plaque Psoriasis

... the health of skin with an extensive line of products across the world that treat a range of dermatological conditions including: acne, rosacea, fungal nail infections, psoriasis & steroid-responsive dermatoses, pigmentary disorders, medical solutions for skin senescence and skin cancers. With a ...

RHEI Pharmaceuticals Announces the Initiation of the Final Clinical Study for Approval of Tibozole in China

... systemic absorption could create issues in patients." About Oral Candidiasis Oral candidiasis, which is sometimes called thrush, is a fungal infection of the mouth and/or throat caused by Candida albicans, although other related Candida may be involved. It appears as thick white or ...

NanoBio Demonstrates New Topical Approach to Treating Nail Fungus That Circumvents Problems with Current Therapy

... concentration required to kill the fungus in the very center of the nail bed. Only 4 micrograms per gram of tissue are required for NB-002 to kill fungal infections. Newer, more effective therapies for nail fungus are important because onychomycosis remains a large unmet medical need, according to ...

CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years

... for full prescribing information for CIMZIA. Tuberculosis (frequently disseminated or extrapulmonary at clinical presentation), invasive fungal infections, and other opportunistic infections, have been observed in patients receiving CIMZIA. Some of these infections have been fatal. ...

CIMZIA(R) (Certolizumab Pegol) Provides Long-Term Benefit Without Dose Escalation in Crohn's Disease Patients

... information, please visit http://www.ucb-group.com . Tuberculosis (frequently disseminated or extrapulmonary at clinical presentation), invasive fungal infections, and other opportunistic infections, have been observed in patients receiving CIMZIA. Some of these infections have been fatal. ...

Video: Sirion Therapeutics Launches Durezol for Postoperative Ocular Inflammation and Pain

... may increase the hazard of secondary ocular infections, exacerbate the severity of ocular viral infections, and increase the development of fungal infections of the cornea. It is important to monitor intraocular pressure when using ophthalmic steroids. The use of steroids after cataract surgery ...

CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohn's Patients

... information, please visit http://www.ucb-group.com . Tuberculosis (frequently disseminated or extrapulmonary at clinical presentation), invasive fungal infections, and other opportunistic infections, have been observed in patients receiving CIMZIA. Some of these infections have been fatal. ...

Keraderm to Release $100 Phototherapy Treatment for Fungal Nail Infections

... /PRNewswire/ -- Keraderm, a leader in the development of phototherapy treatments for infections, plans to introduce a $100 phototherapy treatment for fungal nail infections (onychomycosis) in 2009 upon completion of their current pivotal trials and pending marketing clearance from the FDA. "Our goal," ...

Cimzia(R) Provides Long-Term Efficacy with Stable Dosing in Crohn's Disease

... http://www.Cimzia.com . IMPORTANT SAFETY INFORMATION Tuberculosis (frequently disseminated or extrapulmonary at clinical presentation), invasive fungal infections, and other opportunistic infections, have been observed in patients receiving Cimzia(R). Some of these infections have been fatal. ...

Foamix and Galderma to Develop Medicated Foam for Certain Skin Diseases

... committed to improving the health of skin with an extensive line of products to treat a range of dermatological conditions including: acne, rosacea, fungal nail infections, psoriasis & steroid-responsive dermatoses, pigmentary disorders, skin cancers and medical solutions for skin senescence. With a new ...

Pew Commission Says Industrial Scale Farm Animal Production Poses 'Unacceptable' Risks to Public Health, Environment

... Antibiotics are used to prevent and treat bacterial infections and as growth promoters. Pesticides are used to control insect infestations and fungal growth. Heavy metals, especially zinc and copper, are added as micronutrients to the animal diet. According to a 2006 UN report, globally, ...

DermaGen AB Receives Over 1 Million Euros From a New Share Issue

... A specialty pharmaceutical company focusing on the development of topically applied products for the prevention and treatment of bacterial and fungal skin infections. Based on novel antimicrobial peptides, modified to increase potency and stability the products are designed to fulfil unmet medical ...

Anacor Pharmaceuticals Announces Positive Results from Phase 2a Clinical Trial of AN2728 in Psoriasis Patients

... Anacor's most advanced product candidate is AN2690, a novel topical antifungal in development for the treatment of toenail onychomycosis, which is a fungal infection of the nail and nail bed. Anacor entered into a worldwide license, development and commercialization agreement for AN2690 with ...

NanoBio Corporation Completes Interim Analysis of Phase 2 Clinical Trial in Onychomycosis

... mentagrophytes, Epidermophyton floccosum, Microsporum canis and Candida albicans. About Onychomycosis Onychomycosis is a chronic, persistent fungal infection of the nail bed resulting in unsightly thickening and discoloration of the nail, which sometimes can be accompanied by pain and disability. ...

Pharmion and MethylGene Announce U.S. Orphan Drug Designation Granted for MGCD0103 for the Treatment of Acute Myelogenous Leukemia

... and VEGF receptor tyrosine kinases. In addition, MethylGene's preclinical programs include: MGCD290 an HDAC inhibitor in combination with azoles for fungal infections and a sirtuins program for cancer. MethylGene's development and commercialization partners include Pharmion Corporation, Taiho ...

Pharmion and MethylGene Announce Orphan Drug Designation Granted by the European Medicines Agency (EMEA) for MGCD0103 for the Treatment of Acute Myelogenous Leukemia

... and VEGF receptor tyrosine kinases. In addition, MethylGene's preclinical programs include: MGCD290 an HDAC inhibitor in combination with azoles for fungal infections and a sirtuins program for cancer. MethylGene's development and commercialization partners include Pharmion Corporation, Taiho ...

Beckman Coulter Announces Licensing Agreements for Molecular Tests with National University of Ireland, Galway

... market in the United States. The assay development research relies on NUI Galway nucleic acid detection technology for both bacterial and fungal targets along with SPRI(R) (Solid Phase Reversible Immobilization) and other technologies from Beckman Coulter. Whelan added, "The combination of ...
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Breaking Biology News(10 mins):Fred Baxendale selected as Honorary Member of the Entomological Society of America 2Small molecule acts as on-off switch for nature's antibiotic factory 2Small molecule acts as on-off switch for nature's antibiotic factory 3
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