Bionovo Discovers New Estrogen Regulatory Elements for Breast Cancer and Osteoporosis Drugs

... results on the role of estrogen regulatory elements important in developing drugs for breast cancer ... Annual Meeting, showed that the new regulatory elements are essential for the differentiation of the ... advantage of the new array of specific regulatory elements is manifest in the pharmacological ...

BioCryst Updates Peramivir Clinical Development Plan

... and pandemic preparedness. The key elements of the HHS contract remain the same. The contract ... HHS has indicated that they will fund certain elements of the revised program, including the ongoing ... manufacturing and toxicology. Each of these elements has specific HHS funding limits. Any costs in ...

Artelis and Selexis Report Record Antibody Production Levels in CHO Cells of Over 31 Grams Per Liter

... . About the Selexis Genetic Elements(TM): Selexis Genetic elements (TM) are applied to control the dynamic organization of transgenes in the ... portfolio is based on the discovery and application of enabling genetic elements that control the dynamic organization of chromatin within all mammalian ...

Medigus and Tower Semiconductor Announce World's Smallest Medical Video Camera Based on Advanced CMOS Image Sensor

... of GERD, one of the most common chronic diseases in the western world. Medigus has an advanced technology platform that includes the necessary elements for developing a wide range of endoscopic procedures. The platform includes various CCD and CMOS video cameras developed by Medigus. Each camera ...

Teeth and Gums Also Benefit from the Healing Power of Aloe Vera

... arresting pain because they are anti-inflammatory in nature. Aloe vera tooth gel tends to be less harsh on teeth, as it does not contain the abrasive elements typically found in commercial toothpaste, and is a great alternative for people with sensitive teeth or gums. But buyers must beware. Not ...

Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) for the Treatment of Fabry Disease

... for the treatment of Fabry disease. The Company has reached agreement with the U.S. Food and Drug Administration (FDA) on the key protocol design elements of the pivotal trial, including the use of the surrogate primary endpoint of the change in the amount of kidney interstitial capillary GL-3, the ...

New Therapy Enlists Immune System to Boost Cure Rate in a Childhood Cancer

... PHILADELPHIA, May 28 /PRNewswire-USNewswire/ -- A multicenter research team has announced encouraging results for an experimental therapy using elements of the body's immune system to improve cure rates for children with neuroblastoma, a challenging cancer of the nervous system. John M. Maris, ...

Logical Therapeutics Appoints Peter A. Lankau as CEO and Director

... public company, his execution of numerous business development transactions, and his understanding of the commercially important, and value creating elements of drug development, will help propel Logical toward significant business opportunities in the future." Top Line Study Results Logical ...

Arrayit to Mass Produce Rapid H1N1 Swine Flu Test Chip

... World Health Organization (WHO). The CDC and WHO believe that the current outbreak poses a pandemic risk because the H1N1 flu virus contains genetic elements from both the swine and human influenza viruses, allowing direct human-to-human transmission without the need for agricultural contact. The dangerous ...

Edifecs, CAQH and Harvard Pilgrim Health Care Will Examine CORE Phase II Testing Outcomes and Lessons Learned at HIMSS09 Interoperability Showcase

... its partners CAQH and Harvard Pilgrim Health Care, examine the outcomes and lessons learned from the CORE Phase II Certification testing including elements of the newly mandated 5010 Rules, in a presentation at the HIMSS09 Interoperability Showcase, on Tuesday, April 7, 11:15 AM - 11:45 AM (CT). ...

ExonHit Reports Proof-of-Concept in Breast Cancer Diagnostic Using its SpliceArray(TM) Platform

... Alternext of NYSE Euronext Paris. For more information, please visit http://www.exonhit.com . Disclaimer This press release contains elements that are not historical facts including, without limitation, certain statements on future expectations and other forward-looking statements. Such ...

Certification Commission for Healthcare Information Technology to Develop Dermatology-Specific Functionality Criteria for Electronic Health Record (EHR) Technology

... health records and the smooth and secure interchange of data. Dermatologists are committed to helping create functional criteria and technical elements that also will help many different physician specialties." CCHIT will appoint a work group of volunteer providers, payers, health IT vendors and ...

Experience Not Always the Best Prescription for Snowblowers

... safety features for snowblowers would aid in reducing hand injuries ( http://orthoinfo.aaos.org/topic.cfm?topic=A00014 ), and recommends design elements such as chute openings that would prevent operators from inserting their hands and blades that lock when the handle is released. It also recommends ...

Octogenarians: Not Too Old for Joint Replacement

... 1998 and December 2006. The results were measured using two quality-of-life scales, the SF-36 and the Oxford Knee Score, which assign scores to elements of physical and emotional health, such as: physical pain social functioning vitality physical functioning ...

ExonHit Therapeutics Reports Advancements in the Clinical Development of EHT 0202, its Phase II Drug for Alzheimer's Disease

... ALEHT) since November 17, 2005. For more information, please visit http://www.exonhit.com . Disclaimer This press release contains elements that are not historical facts including, without limitation, certain statements on future expectations and other forward-looking statements. Such ...

Savient Provides Update on Pegloticase BLA

... would be strengthened by revising the Risk Evaluation and Mitigation Strategy (REMS) program. The revised REMS program proposed is based on an elements To Assure Safe Use (ETASU) program. ETASU is a performance-linked access program for prescribers, infusion sites and patients that will have to ...

Nplate(R) Approved in the European Union for the Treatment of Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

... approved peptibody, an innovative platform for delivering targeted therapies." About Adult ITP In patients with ITP, platelets - or blood elements needed to prevent bleeding - are destroyed by the patient's own immune system. Low platelet counts leave adult ITP patients open to sudden serious ...

MannKind Reports Successful Completion of Device Bioequivalence Trial

... our pivotal Phase 3 program, we now have a clear path to submission of the AFRESA NDA. With study 138 complete, there are no longer any outstanding elements of the NDA and we expect to have the complete NDA submitted to FDA within the next few weeks." About AFRESA AFRESA is an ultra rapid ...

MRI Emerges As Vital Resource in Treatment of Back Pain

... if you want to find out which disk is causing pain, which nerve is firing, which metabolites are present in abnormal amounts, or how well the spinal elements are functioning, MR will provide the answers," adds Dr. Haughton. Disclosure : Neither Dr. Haughton or any member of his immediate ...

OmegaGenesis Unveils Novel Nanotechnology Platform With Broad Biomedical Applications

... Calif., Dec. 15 /PRNewswire/ -- OmegaGenesis today unveiled the company's novel technology platform which employs nano-materials made of rare earth elements with angiogenic properties. Nanorod therapies for wound healing, diabetic foot ulcers and hair growth are being developed by the company, with plans ...

NCI Funded Clinical Trial to Study Treatment of Breast Cancer Using Cryoablation

... 94th Scientific Assembly and Annual Meeting in Chicago. Both the pilot study and pending ACOSOG clinical trial share the common clinical protocol elements of cryoablation followed by MRI, surgical resection of the tumor and subsequent pathological evaluation. "Cryoablation has been used effectively ...

Sequoia Pharmaceuticals Presents In Vitro and First-in-Human Data Supporting Further Development of SPI-256, a Novel Investigational Protease Inhibitor

... and was advanced to clinical studies. In vitro activity data were also presented in this poster. These data demonstrated how the structural design elements of SPI-256 present a high genetic barrier to the emergence of resistant strains of HIV. Additionally, the unique structural properties of SPI-256 ...

PTC Announces Data Showing That PTC124 Causes Statistically Significant Improvements in Chloride Channel Function in Cystic Fibrosis Patients

... from the Phase 2 clinical development program for PTC124 in CF," noted Dr. Campbell. "Our alliance with PTC and the development of PTC124 are key elements of our strategic work supporting novel therapeutic approaches with the potential to modify the course of CF. We look forward to continuing our work ...

Amylin Pharmaceuticals to Present Novel Data on Promising Obesity Pipeline at 2008 Annual Scientific Meeting of The Obesity Society

... risk activities, serious injuries may occur. Appropriate patient selection, careful patient instruction, and insulin dose adjustments are critical elements for reducing this risk. This information is highlighted in a boxed warning in the SYMLIN prescribing information for healthcare professionals and in ...

Napo Announces Positive Clinical Data Indicating Crofelemer, Could Effectively Treat Cholera

... to lower dosing regimens with crofelemer, and also include the treatment of children with development of a pediatric formulation of the product. elements of the cholera study in Bangladesh were funded by the National Institutes of Allergy and Infectious Disease. Napo is currently conducting a Phase 3 ...

Rapid Test for Pathogens Developed By K-State Researchers Could Be Used to Detect Diseases Used By Bioterrorists

... and zoonotic pathogens; zoonotic pathogens can be transmitted between humans and animals. The test also is being used to monitor the flow of genetic elements in food production systems, such as feedlots. However, Narayanan hopes the test one day will be used to enhance the clinical diagnosis of animal and ...

ACORN Showcases Oncology CRO, EDC, PRO and Data Warehouse at 44th Annual DIA Meeting

... demonstrates its continued leadership in capturing unique electronic data into a single platform for easy access across the full range of data elements and conducting scientific analysis to generate reliable information solutions in the oncology industry. Analytical data from ACORN's oncology data ...

Sunesis Pharmaceuticals Presents Data from Clinical Trials of Voreloxin (formerly SNS-595) in Patients with Acute Myeloid Leukemia at the 13th Congress of the European Hematology Association

... complete remission (CR) or complete remission without platelet recovery (CRp) or complete remission with incomplete recovery of hematopoeitic elements (CRi) when voreloxin was administered at doses of 50 mg/m2 or greater weekly or 40 mg/m2 twice-weekly. Duration of complete remissions (CR or CRp) ...

Metabolex Completes Patient Enrollment in Phase 2 Trial of MBX-8025 for Treatment of Dyslipidemia

... collectively as mixed dyslipidemia. Though some drugs have marked effects on some of these parameters, existing treatments do not optimally treat all elements of this common condition. About MBX-8025 Earlier testing of MBX-8025 has suggested that the drug has the potential to improve a number of ...

Use of Mealtime SYMLIN(R) Compared to Rapid-Acting Insulin for Diabetes Therapy Intensification in Patients With Type 2 Diabetes Using Basal Insulin

... activities, serious injuries may occur. Appropriate patient selection, careful patient instruction, and insulin dose adjustments are critical elements for reducing this risk. This information is highlighted in a boxed warning in the SYMLIN prescribing information for healthcare professionals and in ...

Leading Immunologists Convene in Boston

... to traditional medical meetings which focus on particular medical specialties, the FOCIS approach is to highlight and probe the underlying common elements of diseases which can lead to better therapies. "As the immunology field rapidly advances in clinical trials and the introduction of new and specific ...

Discovering How Video Games Can Motivate Healthy Behaviors: More than $2 Million Awarded to 12 Research Teams Across U.S.

... The game is designed to motivate real-world wellness through a player support system that involves family members and friends, and by incorporating elements from virtual pets, role-playing games and online social networking. A single-player version provides a fictional game character that offers ...

Spherix D-tagatose to be Supplied by Inalco SpA

... agreement. Financial terms were not disclosed. "This is a significant accomplishment toward achieving our goal of putting in place all the elements needed for a complete NDA submission," said Claire Kruger, CEO of Spherix. Spherix is currently seeking approval from the US Food and ...

Michael J. Fox Foundation Announces $5.6-Million Award for Phase 2 Clinical Trial Studying Neuroprotective Potential of Inosine

... Michael A. Schwarzschild, MD, PhD, of the MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, will oversee all elements of the trial. -- Co-principal investigator Alberto Ascherio, MD, DrPH, of the Harvard School of Public Health, will assist in all aspects of ...

Study Shows Intradigm's RNAi Nanoplex Technology To Be Effective Systemic siRNA Delivery Platform for the Treatment of Various Cancer Models

... siRNAs in a single drug product. These multi-targeted therapeutics can simultaneously silence several mRNAs that represent parallel or synergistic elements of the same disease pathway resulting in a more comprehensive and/or novel therapeutic potential. Recent technology licensing agreements with ...

Arpida Provides Further Comments on the Pivotal Phase III Trials

... April 11 /PRNewswire-FirstCall/ -- Further to the press release published on 9 April, Arpida Ltd. (SWX: ARPN) today elaborates on some additional elements of the clinical programme with intravenous iclaprim in complicated Skin and Skin Structure Infections (cSSSI). Extensive data on ASSIST-1 has been ...

Successful Clinical Trials and Launch in New Zealand Spurs Phloe to Enter US Market

... for a natural and proven digestive aid. Said Mr Wilkinson "Phloe is a unique product as it offers a combination of three of the key elements essential for good digestion -- enzymes, prebiotics and fiber -- which are all derived from one natural ingredient -- New Zealand green kiwifruit." ...

DuPont Provides Technology for Washington Hospital Center's Emergency Department

... for Health Design, Washington Hospital Center will conduct evidence-based research over a two-year period, allowing staffers to test and adjust key elements for the full ER One, which is expected to open in six to 10 years. Washington Hospital Center is a not-for-profit 926-bed acute care teaching and ...

Semafore's SF1126 Exhibits Antitumor and Antiangiogenic Activity

... In the studies reported, SF1126 showed favorable pharmacokinetics and pharmacodynamic effects as indicated by inhibition of downstream signaling elements both in vitro and in vivo. In addition, SF1126 displayed potent antitumor and antiangiogenic activity in vivo, in mouse models, against a variety ...

European Commission Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for Virologically Suppressed Adults With HIV-1 Infection

... guidance provided on the third quarter 2007 earnings conference call on Oct. 18, 2007. Gilead is also not making adjustments to any of the other elements of guidance, including its updated Research & Development guidance of a range from $510 million to $520 million provided on Nov. 6, 2007, which ...