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Disability in Medical Technology

Two-Year Data Reinforce Effect of ACTEMRA(R) (tocilizumab) in Inhibiting Progression of Joint Damage and Improving Physical Function in Rheumatoid Arthritis Patients

... measured by the Health Assessment Questionnaire disability Index (HAQ-DI) scores(1). The LITHE study is the ... joint damage, which is a major cause of disability and loss of physical function for RA patients," ... law. (1) The Health Assessment Questionnaire disability Index (HAQ-DI) is a 20-item questionnaire that ...

Two-Year Phase III Data Presented at AAN 61st Annual Meeting Show Positive Outcome of Cladribine Tablets in Patients With Multiple Sclerosis

... Measures, Proportion of Patients Relapse-Free and disability Progression - Submission for Registration of ... reduction in the rate of clinical relapses, disability progression and brain lesions, as well as a ... led to a more than 30% reduction in the risk of disability progression (another secondary endpoint) relative ...

Oh, My Aching Back: Give Me a Shot of Ozone

... Back pain is the most common cause of job-related disability and a leading contributor to missed work. While ... treatment in regards to pain relief, reduction of disability and risk of complications. More than 8,000 ... improvement was 25.7 percent for the Oswestry disability Index (ODI), which measures one's ability to ...

New Study Confirms That the Supports Intensity Scale Assessment is Effective in Measuring the Support Needs of People With Intellectual Disability and Making Funding Decisions

... receiving funding from a state developmental disability agency WASHINGTON, Feb. 25 ... predict funding for people with intellectual disability based on individual needs, and it is truly a ... receiving funding from a state developmental disability agency. The study, titled, " Efficacy of the ...

New Study Demonstrated ACTEMRA(R) (tocilizumab) Inhibited Progression of Joint Damage in Rheumatoid Arthritis Patients

... joint damage, which is a major cause of disability and loss of physical function for RA patients," ... measured by the Health Assessment Questionnaire disability Index (HAQ-DI).(4) About the LITHE Study ... (4) The Health Assessment Questionnaire disability Index (HAQ-DI) is a 20-item questionnaire that ...

New Minimally Invasive Surgical Procedure Restores Quality of Life in Patients With Potentially Debilitating Spinal Condition

... procedure successfully eliminates pain and disability caused by lumbar spinal stenosis (LSS), a ... designed to assess improvement of pain and disability with commonly used measurement instruments, as ... mean pain score decreased 90 percent and the mean disability score improved 84 percent, compared to baseline. ...

Top-Line Efficacy Data Presented from Phase 2 Trial of Alemtuzumab in Multiple Sclerosis

... risk for progression of clinically significant disability when compared to patients treated with interferon ... and the time to Sustained Accumulation of disability over six months as measured by Expanded disability Status Scale [EDSS]. Efficacy assessments were ...

Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression

... a validated scale called EDSS (Expanded disability Status Scale).(1) Disability progression was ... and robust predictor of permanent and severe disability later in the disease.(2) "This research has ... first clinical event suggestive of MS can delay disability progression." About BENEFIT BENEFIT is a ...

Dirucotide Does Not Meet Primary Endpoint in Phase III MAESTRO-01 Trial in Secondary Progressive Multiple Sclerosis

... endpoint of delaying disease progression, as measured by the Expanded disability Status Scale (EDSS), during the two-year MAESTRO-01 Phase III trial in ... the secondary progressive form of the disease(vi), in which irreversible disability accumulates more steadily, with or without relapses(vii). There are few ...

Data Demonstrated ACTEMRA(R) (tocilizumab) Significantly Inhibited Progression of Structural Joint Damage in Rheumatoid Arthritis Patients

... treatment with ACTEMRA, as measured by the Health Assessment Questionnaire disability Index (HAQ-DI).(3) An additional study to be presented at the ... occurred since treatment began. (3) The Health Assessment Questionnaire disability Index (HAQ-DI) is a 20-item questionnaire that asks about physical ...

Five-Year Data Confirm That Early Treatment with Betaseron(R) at First Sign of Disease Can Delay Progression to MS

... progressive disease of the central nervous system and the likelihood of disability increases the longer someone has MS. Symptoms of MS vary from person to ... L et al. Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3-year ...

Merck Serono Completes Enrollment in the REFLEX Trial of Rebif(R) in Patients at Risk of Developing Multiple Sclerosis

... findings and the current or future clinical status of patients, including disability progression, is unknown. About Rebif(R) Rebif(R) (interferon beta-1a) ... findings and the current or future clinical status of patients, including disability progression, is unknown. About Merck Serono and multiple sclerosis ...

Interleukin Genetics to Present Important New Findings at 2008 World Congress on Osteoarthritis

... debilitating, degenerative joint disease and the leading cause of physical disability in modern societies. According to data on the American College of ... structural deterioration impairs the quality of life and often leads to disability and joint replacement. In the U.S. approximately 500,000 patients received ...

Shire Reports Positive Results From First of Three Phase III Trials of velaglucerase alfa for Type 1 Gaucher Disease and Provides Important Updates on Interactions With FDA

... the body, caused by a genetic mutation received from both parents. The disease course is quite variable, ranging from no outward symptoms to severe disability and death. Carrier status can be detected through blood or saliva to identify potential carriers of the Gaucher gene. Gaucher Disease can be ...

FDA Advisory Committee Votes in Favor of SAPHRIS(R) (asenapine) for Acute Bipolar I Disorder and Acute Schizophrenia

... and increased energy), depression (overwhelming feelings of sadness, suicidal thoughts), or a combination of both. It is the sixth leading cause of disability in the world, affecting approximately 1 to 5 percent of adults, including 10 million Americans. About half of the patients with bipolar disorder who ...

Economy is Driving Many Osteoporotic Women to Retire Later - But Their Ability to Work May Be Undermined by Sub-Optimal Management of Their Disease

... accessed 3/18/2009: Parapgraph 3 (8) Kanis, OG et al. An Estimate of the Worldwide Prevalence and disability Associated with Osteoporotic Fractures. Osteoporosis International 2006; 17:1726 (9) http://www.nof.org/osteoporosis/diseasefacts.htm ...

Shire Receives Fast Track Designation for velaglucerase alfa for Gaucher Disease

... the body, caused by a genetic mutation received from both parents. The disease course is quite variable, ranging from no outward symptoms to severe disability and death. Carrier status can be detected through blood or saliva to identify potential carriers of the Gaucher gene. Gaucher Disease can be ...

Shire has Filed a Treatment Protocol for Velaglucerase Alfa for Gaucher Disease

... the body, caused by a genetic mutation received from both parents. The disease course is quite variable, ranging from no outward symptoms to severe disability and death. Carrier status can be detected through blood or saliva to identify potential carriers of the Gaucher gene. Gaucher Disease can be ...

Mayo Clinic Proceedings Reviews Deep Brain Stimulation to Treat Psychiatric Diseases

... pain receptors. In the developed world, major depression is second only to cardiovascular disease in premature mortality and time lived with disability according to the review. In persons aged 15 to 44 years, depression is the most disabling medical illness in the United States. The prevalence of ...

Sosei and Vectura Announce Start of Phase III Clinical Study With NVA237

... currently the fourth most common cause of death and by 2030 is predicted to become the third most common cause of death and the fourth most important disability causing illness. The total financial burden of lung disease in Europe amounts to nearly EUR102 billion with COPD contributing almost one half of this ...

New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients

... pain, stiffness and motion restriction in multiple joints. Because RA is a progressive disease, it can cause permanent joint deformity and severe disability if not diagnosed early or if initial treatment is delayed. RA can occur at any age, but is most common in adults 30-50 years old and is two to three ...

Merz Pharmaceuticals Announce Three Studies of NT-201 - (Botulinum neurotoxin type A Free From Complexing Proteins)

... the OLEX Period, and were treated with NT-201 (up to five injection intervals) over 1 year (48 to 69 weeks). Parameters were the Ashworth Scale, disability Assessment Scale (DAS), global assessments, and standard safety testing. Out of 148 patients who participated in the double-blind period of the ...

Merz Pharmaceuticals Announces Results of Clinical Trials with NT-201(Botulinum neurotoxin type A free from complexing proteins) at Annual Movement Disorders Society Meeting

... Aquilar, M., Lehnert-Batar, A., and Minnasch, P. Method Responder analysis of at least 1-point improvement from baseline to week 4 on the disability Assessment Scale [DAS] for the primary therapeutic target after injection of a 20 U/mL dilution or 50 U/mL dilution was evaluated. After injection, ...

Three Clinical Presentations on Tapentadol Extended Release Tablets for Chronic Pain Featured at 2009 American Pain Society Annual Meeting

... -- Chronic pain is a significant medical challenge in the United States, and chronic low back pain is the most common cause of disability in developed countries. An estimated 100 million Americans suffer from chronic pain each year. If left undertreated, chronic pain can impair an ...

New Studies on Once-Daily Extended Release Pramipexole Presented at American Academy of Neurology Annual Meeting

... *The Unified Parkinson's Disease Rating Scale (UPDRS) is a comprehensive tool, which was developed to follow the longitudinal course of PD-related disability and impairment. The UPDRS II+ III score was used as the primary efficacy endpoint in both trials. UPDRS Part II relates to activities of daily ...

Surveyed Neurologists Anticipate That Less Than 30 Percent of Their Use of Emerging Oral Agents in Multiple Sclerosis Will be in the First Line

... clinical studies indicating that early initiation of disease-modifying therapies can delay progression of the disease, and specifically, delay disability progression. "Those patients who do not start disease-modifying treatment right away represent an untapped opportunity for marketers of ...

Got Pain?

... University Hospital. "When the 27 bones, cartilage, joints, tendons and nerves in the hand do not work as they should, deformity, motion loss and disability become a painful reality for many people." According to the latest numbers available, in 2006: More than 3 million people ...

American Academy Of Orthopaedic Surgeons 2009 Annual Meeting 'Highlights and Hot Topics'

... Mark ( http://www3.aaos.org/education/anmeet/anmt2009/podium/podium.cfm?Pevent=011 ) Rare Long-Term Study Shows No New Knee disability Even Long After Surgery Patients who were older than 40 and as old as 60 when they underwent ACL surgery reported long-term "excellent ...

Preterm Births Rise 36 Percent Since Early 1980s

... confirm that the decades-long rise in the United States preterm birth rate continues, putting more infants than ever at increased risk of death and disability according to the March of Dimes. Nearly 543,000 babies were born too soon in 2006, according to the National Center for Health Statistics, which ...

Brain Waves Show Sound Processing Abnormalities in Autistic Children

... timing of brain activity," Dr. Roberts said. "We see a fraction of a second delay in autistic patients." Autism is a complex developmental disability that affects approximately one in every 150 American children, mostly boys, according to the Autism Society of America. Autism inhibits the brain ...

NVA237 Phase II Results Presented at the European Respiratory Society Annual Meeting Show Promising Efficacy and Tolerability With Potentially Faster Onset Than Tiotropium

... currently the fourth most common cause of death and by 2030 is predicted to become the third most common cause of death and the fourth most important disability causing illness. The total financial burden of lung disease in Europe amounts to nearly EUR102 billion with COPD contributing almost one half of ...

Landmark COPD Trial UPLIFT(R) Shows SPIRIVA(R) HandiHaler(R) Sustained Lung Function Improvements Over Four Years

... About COPD COPD is a progressive yet treatable disease that restricts patients' lives over time and is a major cause of death and disability throughout the world.(1) COPD is a disease primarily of current and former smokers. It is projected to become the third-leading fatal illness in the ...

Analysis of Earlier European Stroke Trial Supports Treatment Regimen for Viprinex(TM) in Current International Phase 3 Clinical Trials

... dosing regimen, NTI is currently conducting two Phase 3 clinical trials of Viprinex to investigate whether ancrod can safely and effectively reduce disability following an acute ischemic stroke. The trials are being conducted in 14 countries throughout the world, and to date have enrolled over 500 patients. ...

Enobia Pharma Receives FDA Orphan Drug Designation for Hypophosphatasia Product Candidate ENB-0040

... a potential drug therapy for the patients with hypophosphatasia, an under-recognized disease that can be fatal in infants and cause serious disability in older patients that has no currently approved FDA treatment," said Robert Heft PhD, Chief Executive Officer of Enobia. "The recent dosing of the ...

Merck Serono Announces Initiation of the ORACLE MS Trial to Evaluate Cladribine Tablets in Patients at Risk of Developing Multiple Sclerosis

... for prescribing information. * The exact correlation between MRI findings and the current or future clinical status of patients, including disability progression, is unknown. About Merck Serono and multiple sclerosis Merck Serono is a leader in multiple sclerosis (MS) with Rebif(R) interferon ...

NIH Funds New Wellstone Research Center for Muscular Dystrophy at Boston Biomedical Research Institute

... muscles. In the worst cases, all skeletal muscles are lost, hearing and vision are involved, and respiratory insufficiency can cause severe disability and even death. In addition to Emerson, Kunkel and Perez, the center's network of collaborators includes Kathryn Wagner, M.D., Ph.D., The Johns ...

Neurosciences Institute Discovers Drug Extends Stroke Treatment Time to 24 Hours, Repairs Brain Tissue

... United States, there are more than 780,000 strokes. It is the third leading cause of death in the country and the most common cause of long-term disability in developed countries. Nearly three-quarters of all strokes occur in people over the age of 65 and the risk of having a stroke more than doubles ...

TRANSCEND(TM) Trial Results Presented at European Society of Cardiology Congress and Published in The Lancet

... disease and diabetes combined.(9) By 2020, it is predicted that CVD will surpass infectious diseases to become the largest cause of death and disability worldwide.(10) It is also contributes significantly to the escalating costs of health care. In 2006, the cost of CVD in the U.S. was estimated at ...

Nexgen Spine Receives CE Mark Approval for the Physio-L(R) Artificial Disc

... surgeon to restore function to the patient's disc. The clinical data for the Physio-L(R) are demonstrating outstanding improvements in both patient disability and pain, supporting the concept of using elastomeric polymers for total disc prostheses." Nexgen Spine, Inc. is dedicated to providing its ...

HealthMedia and Aetna to Study Online Insomnia and Depression Interventions

... and consumer-directed health insurance products and related services, including medical, pharmacy, dental, behavioral health, group life and disability plans, and medical management capabilities and health care management services for Medicaid plans. Our customers include employer groups, ...
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(Date:12/10/2014)... , Dec. 9, 2014  Valencell, a leader ... is seeing a staggering demand from its licensees for ... Company revealed, is not solely coming from fitness and ... well. "A wearable is only as useful ... accuracy is the ultimate driver in long-term mass consumer ...
(Date:12/10/2014)... DIEGO , Dec. 9, 2014 CIE ... collaboration catalyst that provides the connective tissue that enhances ... enabling them to easily share client-level information; earned a ... to expand to organizations serving seniors aging in community ... Diego" partner on December 11 th 4-6p. ...
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(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
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(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
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