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FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent

... (aliskiren), the first and only approved direct renin inhibitor, and the diuretic ... pressure treatment goals." Tekturna, a direct renin inhibitor, is the only drug that works by ... was approved in the US in 2007 as the first direct renin inhibitor. In 2008, Tekturna HCT was ...

R&D Spending by U.S. Biopharmaceutical Companies Reaches Record Levels in 2008 Despite Economic Challenges

... companies equaled roughly $65,000 per direct employee in 2006 - about eight times the ... roughly one-quarter of the more than 686,000 direct employees of the sector were engaged in life, ... product. According to the study, the sector's direct contribution to the U.S. GDP of $88.5 billion was ...

Taxus Atlas Studies Reinforce Safety and Efficacy of Boston Scientific's Next-Generation Taxus Liberte Stent

... Friday. Results from the TAXUS ATLAS Workhorse, direct Stenting, Small Vessel and Long Lesion trials ... in small vessels and positive results in direct stenting procedures," said Mark A. Turco, M.D., ... the thin-strut TAXUS Liberte Stent. TAXUS ATLAS direct Stent Dr. Turco also presented two-year data ...

Boston Scientific to Release Broad Range of Clinical Trial Data on the Performance of TAXUS(R) Coronary Stent Systems at TCT 2008

... three-year data from the ATLAS Workhorse and direct Stenting trials and two-year ATLAS data on small ... 12 (all times are ET) -- TAXUS ATLAS Workhorse, direct Stenting, Small Vessel and Long Lesion studies. ... study and two-year data from the TAXUS ATLAS direct Stent study will be presented by the study's ...

Sangamo BioSciences Announces Presentation of Phase 1b ZFP Therapeutic Data at American Diabetes Association Meeting

... a subject's change in vibration sensitivity. direct measurement of the speed and amplitude of ... (VEGF-A). VEGF-A has been demonstrated to have direct neurotrophic and neuroprotective properties. In ... biopsies will also be taken to evaluate the direct therapeutic effect of SB-509 on nerve regrowth. ...

Anadys Pharmaceuticals Initiates Phase I Clinical Trial of ANA598

... treated with combinations of two or more direct antivirals. It is expected that the next ... viral enzymes to inhibit viral replication. These direct antivirals are expected to improve ... with HCV infection and that the full benefit of direct antivirals will be demonstrated when studied ...

Multi-Center Patient Registry Supports Safety and Clinical Utility of Boston Scientific's SpyGlass(R) Direct Visualization System

... clinical utility data for its SpyGlass(R) direct Visualization System, which offers extensive ... The SpyGlass System is the first single-use direct visualization system that requires only a single ... to a camera that provides physicians with a direct view of a patient's bile ducts, overcoming some ...

Nuvelo Begins Phase 2 Trial and Receives Fast Track Status for Alfimeprase in Patients With Acute Ischemic Stroke

... About Alfimeprase Alfimeprase is a recombinant direct acting fibrinolytic (rDAF) that has the potential ... development pipeline includes alfimeprase, a direct acting fibrinolytic in Phase 2 clinical ... and inflammatory bowel disease and NU172, a direct thrombin inhibitor for use as a ...

Study Shows That Low-Molecular Weight Heparin (LMWH) was Associated with Reduced Hospital Costs of Venous Thromboembolism (VTE) Treatment Compared with Unfractionated Heparin (UFH)

... in the real-world practice, the total hospital direct medical costs and VTE-related readmission rates ... for covariates, the average total direct hospital costs were $3,618 for UFH and $3,068 for ... higher drug-related costs for Lovenox, the total direct medical costs for the treatment of VTE is reduced ...

Two Major Studies Show: Human Pluripotent Stem Cells without Cloning or Destroying Embryo

... "On both ethical and practical grounds, direct programming is superior to cloning as a means of ... stem cells for possible stem cell therapies. direct reprogramming of human cells is one of the most ... Dolly, Professor Ian Wilmut, recently stated that direct reprogramming is "extremely exciting and ...

The Lancet Publishes Major Phase 3 Study on Novel Oral Direct Thrombin Inhibitor

... that both doses (220mg and 150mg) of the oral direct thrombin inhibitor, dabigatran etexilate, ... Dabigatran etexilate is an investigational oral direct thrombin inhibitor that specifically and ... trials that are designed to investigate the oral direct thrombin inhibitor as a potential treatment and ...

Neurobiological Technologies' Partner, Celtic Pharma, Announces Results of XERECEPT(R) Phase 3 Clinical Program

... to Placebo New Preclinical Studies Indicate XERECEPT(R) May Have direct Anti-Tumor and Angiogenesis Inhibition Activity New York, London and ... Sutent.(R) These preclinical findings demonstrate that XERECEPT(R) has direct antitumor and angiogenesis inhibition activity, in these models. ...

Spherix Reports First Quarter 2009 Earnings

... Financial Results for the Quarter Ended March 31, 2009 Revenue and direct contract costs grew to $360,670 from $142,908 from the previous year's ... -------- -------- Operating expense direct costs 130,542 61,594 ...

ANA598 Demonstrates Potent Antiviral Activity at all Dose Levels in Completed Phase Ib Study in Hepatitis C Patients

... activity against mutants known to confer resistance to other classes of direct antivirals, including protease inhibitors, nucleoside inhibitors, and ... regimens who may be successfully treated with combinations of two or more direct antivirals. It is expected that the next generation of therapies for ...

Unemployment, Health Care Spending Affect Mortality

... Specifically, unemployment and reduced spending on health care have a direct effect on the country's mortality rate. "We have seen this ... disease," Brenner related. "But these are the first findings that show a direct correlation between reduced health care expenditures and reduced labor ...

ANA598 Demonstrates Potent Antiviral Activity in an Early Clinical Study in HCV-Infected Patients

... the rate of initial viral load decline, believed to be associated with direct inhibition of viral replication, is greater than has been reported ... regimens who may be successfully treated with combinations of two or more direct antivirals. It is expected that the next generation of therapies for ...

Portola Pharmaceuticals Initiates Phase II Trial of Novel IV and Oral Anti-Platelet Drug in Non-Urgent Percutaneous Coronary Intervention

... Medical Center in Durham, NC. "PRT060128 appears to be a novel, direct acting, reversible anti-platelet agent and we are very interested to see ... Advancing Patient Care PRT060128 is the only reversible, direct acting, IV and oral ADP receptor antagonist in clinical development. ...

Roche, InterMune and Pharmasset Announce Initiation of INFORM-1, the First Dual-Combination Clinical Trial with Oral Antivirals in Hepatitis C

... therapy in treatment-naive patients infected with HCV genotype 1. This direct antiviral combination study represents an important first step in ... pleased to participate in the first clinical exploration of an all-oral, direct antiviral regimen towards that goal." "The combination of oral antiviral ...

CEL-SCI Announces Expansion of Exclusive Licensing Agreement for Cancer Drug Multikine

... Partner to Make direct Investment in CEL-SCI VIENNA, Va., Nov. 3 /PRNewswire-FirstCall/ -- ... part of the clinical study in its territory. In addition to making a direct investment in the Company and funding a portion of the clinical trials, ...

Unprecedented 8th Year Start Up of National Direct AmeriCorps Program Access to Care Through Service (ACTS) Parent, Lead Organization The Philadelphia AIDS Consortium and World Health Care Infrastructures

... Care Infrastructures is launching its 8 year of only one of two national direct AmeriCorps programs with focus on targeting those infected and affected by HIV/AIDS to work in direct community service to their communities. Access To Care through Service ...

Anadys Pharmaceuticals Announces Successful Outcome of ANA598 Healthy Volunteer Study and Finalization of Study Design for Phase Ib Trial in HCV Patients

... undiminished activity against a number of HCV variants resistant to other direct antivirals currently in development. Clinical Need and Market ... regimens who may be successfully treated with combinations of two or more direct antivirals. It is expected that the next generation of therapies for ...

The First Direct Structural Evidence of SV2A has Been Revealed Thanks to Protein Tomography(TM), and Published in BBRC

... 9 /PRNewswire/ -- Sidec AB has together with UCB published the first direct structural evidence of the molecular mechanism of the Synaptic Vesicle ... (LEV; Keppra(R) is a trademark of UCB). The result shows the first direct structural proof of the "alternating access model" that has been proposed ...

Nuvelo Announces Positive Phase 1b Proof-of-Concept Data With Anticoagulant NU172

... from the Phase 1b proof-of-concept trial of NU172, demonstrating that the direct thrombin inhibitor rapidly produced and maintained anticoagulation with a ... medical conditions. Nuvelo's development pipeline includes NU172, a direct thrombin inhibitor which has completed Phase 1 development for use as a ...

Cardium Reports on Second Quarter 2008 Highlights and Financial Results

... training at Duke University. -- Completion of two follow-on registered direct investments by institutional and other accredited investors with gross ... debt obligations to Life Sciences Capital; and completed a registered direct investment resulting in gross proceeds of approximately $3.34 million, ...

(RED) to Launch New Way for People to Get Music in Their Lives; Weekly Delivery of Great Music Helps to Save Lives in Africa

... programs. This idea lives at the core of the (RED) mission. "This new direct link to customers is very important to (RED). Not only because it creates ... for those living with AIDS in Africa, but also because it gives us a direct relationship with (RED) consumers, creating a new platform to communicate ...

InterMune Announces Start of 14-Day Triple Combination Study of ITMN-191 in Patients With Chronic Hepatitis C

... with various antiviral compounds, including other small molecule direct antivirals, in both treatment-naive and treatment-experienced patients." ... as well as in-vitro results of ITMN-191 in combination with various direct antiviral compounds. About InterMune InterMune is a biotechnology ...

DATATRAK International Reports First Quarter Results for 2008

... of the 41% decrease in revenue partially offset by a 30% reduction in direct costs. DATATRAK's backlog at March 31, 2008 was $13.9 million and ... Revenue $2,088,229 $3,542,095 direct costs 933,879 1,337,471 ...

Study Results of GAMMAGARD S/D and GAMMAGARD LIQUID in Patients with Mild-to-Moderate Alzheimer's Disease Announced

... IGIV products can contain blood group antibodies that may cause a positive direct antiglobulin reaction and, rarely, hemolysis. Aseptic meningitis ... IGIV products can contain blood group antibodies that may cause a positive direct antiglobulin reaction and, rarely, hemolysis. Thrombotic events have ...

Micromet Shows Feasibility of Subcutaneous Delivery of BiTE Antibody in Preclinical Primate Study

... administered BiTE(R) antibodies(1). BiTE antibodies are designed to direct the body's cytotoxic, or cell-destroying, T cells against tumor cells, and ... No. 2403. About BiTE Antibodies BiTE(R) antibodies are designed to direct the body's cytotoxic, or cell-destroying, T cells against tumor cells, and ...

Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies

... into a BiTE antibody. BiTE antibodies are designed to direct the body's cytotoxic, or cell-destroying, T cells against selected ... No. 2402. About BiTE Antibodies BiTE(R) antibodies are designed to direct the body's cytotoxic, or cell- destroying, T cells against tumor cells, ...

Status of the E2007 (perampanel) Development Program

... of levodopa. However in neuropathic pain and epilepsy, the rationale is to direct parampanel's demonstrated activity as an AMPA receptor antagonist toward ... Drug Drugs that show efficacy by a mechanism other than direct effects on the dopamine receptor or dopamine metabolism. They ...

Data From Ortho Biotech-Sponsored Studies to be Presented at National Kidney Foundation 2008 Spring Clinical Meetings

... large managed care database was conducted to quantify the incremental direct healthcare costs of CKD in patients with diabetes. Analyses compared diabetes patients who developed CKD versus those who did not for yearly direct healthcare costs, which consisted of outpatient services, inpatient ...

ISAR-REACT 3 Pits Bivalirudin vs. Unfractionated Heparin in PCI

... Will direct thrombin inhibitor excel with high-dose clopidogrel on board? CHICAGO, ... study investigators expect to determine whether bivalirudin, a direct inhibitor of the clotting protein thrombin, is better than unfractionated ...

Micromet Announces Presentation of Five Posters Related to Its Proprietary BiTE Antibody Platform at Annual Meeting of American Association for Cancer Research

... preclinical data for new BiTE antibodies. BiTE antibodies are designed to direct the body's cytotoxic, or cell-destroying, T cells against tumor cells, and ... 14, 2008) About BiTE Antibodies BiTE(R) antibodies are designed to direct the body's cytotoxic, or cell- destroying, T cells against tumor cells, ...

Sangamo BioSciences Reports 2007 Fourth Quarter and Year-End Financial Results

... major crop species -- maize and canola. -- Sangamo closed a registered direct offering to institutional investors. In July, Sangamo sold an ... common stock to a group of institutional investors in a registered direct offering, resulting in gross proceeds to the company of approximately ...

Nuvelo Initiates Phase 1 Clinical Trial of Thrombin Inhibitor, NU172

... medical conditions. Nuvelo's development pipeline includes alfimeprase, a direct acting fibrinolytic in Phase 2 clinical development for the treatment ... disorders including acute ischemic stroke and catheter occlusion; NU172, a direct thrombin inhibitor in Phase 1 development for use as a potential ...

Anadys Pharmaceuticals Announces Positive Results for ANA598 in Animal Model of Chronic Hepatitis C Virus Infection

... our continued enthusiasm for development of ANA598 as a potential new direct antiviral treatment for chronic HCV," said Steve Worland, Ph.D., President ... activities for ANA598 and the belief that ANA598 is an exciting new direct antiviral to investigate for the treatment of patients with HCV infection. ...

Nuvelo Announces Alfimeprase SONOMA-2 Catheter Occlusion Data Presentation Webcast and Conference Call

... medical conditions. Nuvelo's development pipeline includes alfimeprase, a direct acting fibrinolytic in Phase 2 clinical development for the treatment ... therapy-induced mucositis and inflammatory bowel disease and NU172, a direct thrombin inhibitor for use as a potential short- acting anticoagulant ...

Tampax and Always Launch Protecting Futures Program Dedicated to Helping African Girls Stay in School

... reach their full potential." "Protecting Futures is making a positive and direct impact in the lives of children living in HIV/AIDS-affected communities in ... water pipeline to 2 schools in this region. In addition to providing direct access to clean water at these schools for all children and teachers, ...

One Year Study of Exenatide Treatment Showed Improved Beta-Cell Function

... in the United States and costs approximately $132 billion per year in direct and indirect medical expenses(6). According to the Centers for Disease ... http://www.diabetes.org/about-diabetes.jsp . Accessed June 14, 2007 6 direct and Indirect Costs of Diabetes in the United States." American ...
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(Date:9/16/2014)... years after the Hesperides vessel returned to Spain culminating ... have an increasingly clear picture of how the global ... the input of pollutants from the atmosphere is not ... most remote areas of the planet, and it is ... are presented this week in CSIC Residence for Researchers ...
(Date:9/16/2014)... . CRG researchers ... Journal of Cell Biology describes how Topo 2 ... , At this very moment thousands of our body,s cells ... the body repairs damaged tissues and regenerates others like skin ... "mitosis", during which the cell duplicates its genetic material and ...
(Date:9/16/2014)... Sept. 16, 2014  Cross Match Technologies, a ... announced today the launch of its Verifier ® ... identity of an individual using their secure credentials ... rapidly reads credential documents with embedded biometric data ... the biometric to a live scan of their ...
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(Date:9/16/2014)... 15, 2014 For patients with locally advanced pancreatic ... radiation (SABR) may be a promising treatment option, ... not otherwise be an option, according to research ... Oncology,s (ASTRO,s) 56th Annual Meeting. , Surgery is ... pancreatic ductal adenocarcinoma (PDA), the most common type ...
(Date:9/16/2014)... Texas (PRWEB) September 16, 2014 Beginning October ... adding a new service offering for its clients who book ... to the volume of business they buy. Most recurring ... during the work week, but others include clients whose ... pet sitter on a daily basis. The ...
(Date:9/16/2014)... Brightree® , the leading ... software solutions for the post-acute care industry, today ... of Brightree HME , serving home medical ... well as home infusion pharmacies. The release includes ... purchasing, document management and electronic eligibility checking all ...
(Date:9/16/2014)... (PRWEB) September 16, 2014 Synergy Research ... comprehensive report gives the best detail and analysis of ... pulled from a variety of sources, including Ministry of ... Orange Paper will give readers actionable intelligence on clinical ... Paper is relied on by the local and international ...
(Date:9/16/2014)... Valley Cellars and company owner Jay Rosen are featured ... This feature is part of the private cellars section ... company as a whole. , Washington Valley Cellars has ... wine storage solutions for their clients for over 15 ... across the country, especially in New York, New Jersey, ...
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