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Cyclic in Medical Technology

BIOCOM's 4th Annual DeviceFest Honors Companies

... accidental needlestick injuries. "The Far Out" award went to CVAC Systems, Inc for its unique capsule device focused on the application of its cyclic Variations in Altitude Conditioning process to treat diseases and disorders associated with aging, including insulin resistance, diabetes, ...

Michael J. Fox Foundation Awards $2.7 Million to Four Industry Teams for Pre-Clinical Parkinson's Disease Research

... of Disease Progression and Therapeutics Interventions in Parkinson's Disease Patrizia Fanara, Ph.D., KineMed, Inc. Selective Inhibition of cyclic Nucleotide Phosphodiesterase Type 7 (PDE7): A Novel and Efficacious Approach to Treating Parkinson's Disease Vincent Allen Florio, Ph.D., Omeros ...

Ironwood and Collaborators Present Preclinical Data Demonstrating That Cyclic GMP Alleviates Intestinal Pain

... -- Ironwood Pharmaceuticals (formerly Microbia) today announced presentation of data from a pair of preclinical studies delineating the role that cyclic guanosine monophosphate (cGMP) plays in alleviating intestinal pain. These studies demonstrate that cGMP inhibits intestinal pain in a preclinical ...

University of Miami Team Confirms Value of Monitoring Cell-Mediated Immunity Pre- and Post-Transplant in Management of Kidney Transplant Recipients

... recipients," will be presented on June 2 at the annual meeting of the American Transplant Congress in Toronto, Canada. "The production of cyclic adenosine monophosphate (cAMP) by mitogen-stimulated peripheral CD4+ T-cells using the ImmuKnow assay has previously be shown to have utility in the ...

Increases in West Nile Virus Replikin Concentrations Precede Increases in the Number of Human Cases

... specified in virus genomes, which increase in concentration signaling rapid replication before virus outbreaks. This is the first report that cyclic increases in virus replikin concentration, each apparently building on the last, can be a mechanism of virus expansion into a territory. In the ...

Genaera Corporation Announces MSI-1436 Data Presented at Society of Neuroscience Meeting

... a definitive study to resolve this discrepancy was designed. The effects of MSI-1436 on dopamine reuptake were investigated using in vivo fast-scan cyclic voltammetry in anesthetized rats. A stimulation train was delivered to the ventral tegmental area every five minutes and the resultant dopamine and ...

Palatin Technologies, Inc. Reports Initiation of Human Trials for the Treatment of Congestive Heart Failure

... evaluations will include safety, tolerability, pharmacokinetics and several pharmacodynamic endpoints, including endogenous messenger levels such as cyclic guanosine monophosphate. Dr. Trevor Hallam, Palatin's Executive Vice President for Research and Development, stated, "We are excited to begin ...

Replikins LLC Finds West Nile Virus Replikin Count Has Reached Its Highest Recorded Value

... the West Nile peptides has provided advanced warning of the increase of West Nile Virus occurrence beginning to be reported. Advanced warning of the cyclic build-up of West Nile Virus (WNV) is important as preventive measures against the virus's mosquito carrier could be timely activated. The CDC has ...

NIDA Study Identifies Genes That Might Help Some People Abstain from Smoking

... substances include cadherin 13 (a molecule involved in cell adhesion, which governs how cells recognize and connect to their neighbors) and a cyclic G-dependent protein kinase gene (that plays a key role in normal brain development). In addition to genes implicated in intracellular signaling and ...

Poster on Cyclosert Drug Delivery Presented at AACR Meeting

... to overcome limitations in existing technologies used for the systemic transport of therapeutics to targeted sites within the body. Based on small cyclic repeating molecules of glucose called cyclodextrins, Cyclosert promotes the ability of cytotoxic drugs to inhibit the growth of human cancer cells ...

Arrowhead Subsidiaries Insert & Calando Present Data on Cyclosert Drug Delivery System at AACR Meeting

... to overcome limitations in existing technologies used for the systemic transport of therapeutics to targeted sites within the body. Based on small cyclic repeating molecules of glucose called cyclodextrins, Cyclosert promotes the ability of cytotoxic drugs to inhibit the growth of human cancer cells ...

Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes

... normal or elevated, GLP-1 and GIP increase insulin synthesis and release from pancreatic beta cells by intracellular signaling pathways involving cyclic AMP. GLP-1 also lowers glucagon secretion from pancreatic alpha cells, leading to reduced hepatic glucose production. By increasing and ...

An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes

... normal or elevated, GLP-1 and GIP increase insulin synthesis and release from pancreatic beta cells by intracellular signaling pathways involving cyclic AMP. GLP-1 also lowers glucagon secretion from pancreatic alpha cells, leading to reduced hepatic glucose production. By increasing and ...
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