Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009

... including additional expenses associated with the broad Phase 3 clinical program for mipomersen, the lead ... ASCO and ADA, highlighting the versatility and broad applicability of antisense drugs to inhibit ... cardiovascular pipeline, is being evaluated in a broad Phase 3 program in patients who cannot adequately ...

PAREXEL Reaches Milestone in Management of Oncology Trials Over Last Five Years Involving 175,000 Patients Worldwide

... demand for conducting cancer trials across a broad range of indications, PAREXEL continues to ... PAREXEL has experience across a broad range of cancer indications as well as all ... to clinical development programs across a broad range of areas. For more information about ...

Novexel's NXL104/ceftazidime Combination Commences Second Phase II Clinical Trial in Hospital Patients With Complicated Intra-Abdominal Infections (cIAIs)

... antibacterial, which combines Novexel's broad spectrum beta lactamase inhibitor, NXL104, with ... NXL104 in combination with ceftazidime in a broad range of indications where resistant ... ceftaroline, a novel, bactericidal injectable broad spectrum cephalosporin. Ceftaroline is being ...

Novavax Reports Positive Preclinical Results for a Novel, Broadly Cross-Protective H5N1 Pandemic Influenza Virus-like Particle (VLP) Vaccine Candidate

... of the Next Generation of Influenza Vaccines with broad Protection Against Multiple Strains ... at Novavax, was uniquely designed to provide broad protection against several clades (or strains) of ... for development of a vaccine capable of inducing broad cross protection against a variety of strains ...

Pieris Reports Development Progress for Anticalin(R) PRS-050, a Next Generation VEGF Antagonist

... candidate PRS-050, a potent VEGF antagonist with broad therapeutic applicability. Having ... bacterial secretion system ESETEC(R) supports broad therapeutic application of the Anticalin(R) ... protein structure, high intrinsic stability, broad formulation flexibility and small molecular ...

Rib-X Pharmaceuticals Reports Positive Top-Line Results from Phase 2 Study of Delafloxacin

... data for delafloxacin continues to show that this broad spectrum compound is likely to be a valuable tool ... Delafloxacin Delafloxacin is a novel, broad spectrum, next-generation fluoroquinolone, which ... that has demonstrated activity against a broad spectrum of bacteria, including ...

PAREXEL Strengthens Leading Presence in Latin America With a New Location in Peru

... regional and worldwide scale. Included among the broad array of services we provide, we are helping ... advice for clinical development, as well as a broad range of services including project management, ... services organization, providing a broad range of knowledge-based contract research, ...

New Insight Into the Controls on a Go-To Enzyme

... cell and muscle function. The downside of this broad set of responsibilities is that defective or ... also covers regions away from that site. Such a broad molecular embrace guarantees that calpastatin ... down calpain's function, Moldoveanu said. This broad embrace also guarantees that calpastatin will ...

Genzyme and Isis Begin Second Phase 3 Trial Of Mipomersen

... broad New Patent Granted CAMBRIDGE, Mass. and ... of the phase 3 trial in heFH with a very broad patent allowance that expands the patent coverage ... 7,407,943 is the first allowance in a series of broad filings protecting the therapeutic use of ...

Medarex Highlights Strength in Antibody Development and Underlying Pipeline Strategy at R&D Day Event in New York City

... a solid foundation for creating and renewing a broad portfolio of innovative and ... excited and confident of the path forward for the broad oncology program of ipilimumab, our lead product ... In addition to providing an update on the broad program for ipilimumab, an ...

Preclinical Study Presented at AACR Annual Meeting Shows Broad Anti-Cancer Potential of Peregrine's anti-PS Vascular Targeting Antibodies

... Cancer Research (AACR) further illustrates the broad anti-tumor potential of ... immune response. "This study highlights the broad anti-cancer potential of our anti-PS vascular ... of bavituximab and other anti-PS antibodies in a broad range of anti-cancer regimens." Dr. Liang and ...

PAREXEL Expands Global Clinical Pharmacology Capabilities

... based in the London unit have experience across a broad range of therapeutic areas, with ... including Board Certified medical doctors, have a broad range of therapeutic experience, including the ... services organization, providing a broad range of knowledge-based contract research, ...

Landmark ONTARGET(TM) Trial Demonstrates Micardis(R) is Equally Effective as Ramipril, with Fewer Discontinuations, in a Broad High-Risk Cardiovascular Population

... hospitalization for congestive heart failure in a broad cross-section of high-risk cardiovascular ... controlled high blood pressure and a history of a broad range of cardiovascular diseases. The study ... for congestive heart failure. In addition, a broad variety of secondary and tertiary endpoints were ...

HUYA Bioscience Int'l Announces World-Class Clinical Advisory Team for New Anti-Arrhythmic Compound Sourced From China

... contributor to cardiovascular research over a broad area including anti-arrhythmic therapies, genetic ... advantages over other anti-AF agents and exhibits broad spectrum ion channel inhibition without ... market. With three strategic offices in China, a broad Chinese compound portfolio, and exclusive ...

Positive Five-Year Safety Data for TAXUS(R) Stent Reported in Boston Scientific Trial

... infarction, and stent thrombosis across a broad cross section of patients and lesions and with no ... lesion revascularization (TLR) reduction across a broad cross section of patients and lesions. When ... medical devices whose products are used in a broad range of interventional medical specialties. For ...

Innocoll Provides a Progress Update on its Clinical Development Programs and Specialty Pharmaceutical Operations

... implant impregnated with the broad spectrum aminoglycoside antibiotic, gentamicin. ... patients documenting safety and efficacy over a broad range of orthopaedic, colorectal, cardiothoracic, ... BUPIVACAINE SURGICAL IMPLANT is believed to offer broad utility across a variety of surgical ...

Promising Data from Paratek Pharmaceuticals' MAR Inhibitor Program Presented in 'Late Breaker' Session at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy

... Underlying Bacterial Infection and May Have broad Use in Preventing Critical Bacterial Infections ... diseases will be very useful in preventing a broad range of critical bacterial infections." Thomas ... establish infections and develop resistance to a broad range of antibiotics and other toxic substances. ...

MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study

... product offers dose titration capability over a broad range of dose strengths, in a single inhalation. ... dose, all while satisfying the varying needs of a broad continuum of patient populations. The QDose ... piezo electronics to efficiently deliver a broad range of compounds independent of inhalation ...

Amgen Announces Positive Top-Line Results for Denosumab in Trial for Delay of Skeletal Related Events in Bone Metastases Patients Compared to Zometa(R)

... denosumab development program is the largest ever initiated by Amgen. This broad and deep development program demonstrates Amgen's commitment to ... rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing ...

Mayo Clinic Study Finds Earliest Evidence of Memory Decline in Middle-Aged People at Genetic Risk for Alzheimer's Disease

... combination of academic excellence, entrepreneurial energy and broad access. This NewAmericanUniversity is a single, unified institution ... genetic mysteries of life, from emerging trends in climate change to the broad complexities of the human condition. For more information, visit ...

Denosumab Demonstrates Superiority Over Zometa(R) in Pivotal Phase 3 Head-to-Head Trial in Breast Cancer Patients With Bone Metastases

... denosumab development program is the largest ever initiated by Amgen. This broad and deep development program demonstrates Amgen's commitment to ... rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing ...

Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression in Rheumatoid Arthritis Models by Selective Inhibition of the Immunoproteasome

... Findings Published in Nature Medicine Suggest broad Implications for the Treatment of Inflammatory and Autoimmune Disorders ... and can have dramatic impact on the inflammatory response without risking broad suppression of immune system function." Proteolix plans to file an ...

Novavax Completes Enrollment of Its Second Phase II Seasonal Influenza VLP Vaccine Clinical Trial

... vaccine, allowing further evaluation of safety and immunogenicity of a broad range of vaccine doses against a new set of influenza strains. As ... clinical stage biotechnology company, creating novel vaccines to address a broad range of infectious diseases worldwide using advanced proprietary ...

One Step Closer: Novel Opioid Receptor Compound in Phase I Clinical Trials

... of diseases because of its long-lasting effect in animal tests. "The broad goal of a medicinal chemist is to discover a drug that gets widespread use ... develop numerous products as important therapeutics for the treatment of a broad range of diseases and medical conditions, including addiction, pain, and ...

Perceptive Informatics Survey Results Reveal Top Barriers to Implementing Adaptive Trial Designs

... by over 500 professionals from the biopharmaceutical industry, across a broad range of clinical, statistical, and regulatory functions. The survey ... is a leading global biopharmaceutical services organization, providing a broad range of knowledge-based contract research, medical communications and ...

NovaBay(R) Pharmaceuticals Enters into Agreement to Broaden Intellectual Property Estate and Expand Clinical Opportunities for Its Aganocide(R) Compounds

... to the research agreement, NovaBay has obtained an exclusive license to a broad portfolio of intellectual property covering uses of NCT compounds. As a ... render most antibiotics ineffective. These compounds have a potentially broad therapeutic index providing a high degree of potency, good tolerability ...

Rib-X Pharmaceuticals Novel Antibiotic Delafloxacin Named One of R&D Directions 100 Great Investigational Drugs of 2009

... Susan Froshauer, PhD, President and CEO of Rib-X Pharmaceuticals. "The broad spectrum activity demonstrated by delafloxacin against a wide range of ... . About Delafloxacin Delafloxacin, a novel, broad spectrum, next-generation fluoroquinolone, has demonstrated better ...

Innocoll Announces Dosing of Last Patient in Second US Phase 3 Clinical Trial to Investigate GENTAMICIN SURGICAL IMPLANT for Prevention of Surgical Site Infections in Colorectal Surgery Patients

... a fully biodegradable, leave-behind surgical implant impregnated with the broad spectrum aminoglycoside antibiotic, gentamicin. It is designed to provide ... totaling over 7,500 patients documenting its safety and efficacy over a broad range of orthopedic, colorectal, cardiothoracic, vascular, and ...

Varian Medical Systems to Exhibit Cancer Treatment and X-ray Imaging Technologies at China Med Exhibition

... placing tiny radiation sources directly into a targeted tumor. A broad array of X-ray tubes and the company's PaxScan(R) line of flat-panel ... largest selection of X-ray tubes and digital image detectors to serve in a broad range of applications," said Hsiao-Li Pan, manager of Varian's X-ray ...

Innocoll Announces Dosing of Last Patient in US Phase 3 Clinical Trial to Investigate GENTAMICIN SURGICAL IMPLANT for Prevention of Surgical Site Infections in Cardiac Surgery Patients

... a fully biodegradable, leave-behind surgical implant impregnated with the broad spectrum aminoglycoside antibiotic, gentamicin. It is designed to provide ... totaling over 7,500 patients documenting its safety and efficacy over a broad range of orthopedic, colorectal, cardiothoracic, vascular, and ...

DSM Obtains Exclusive World-Wide License for Innovative Drug Delivery Technology

... into DSM's Trancerta(R) Drug Delivery platform, this will open up a broad range of opportunities for next generation drug delivery. DSM's activities ... our novel biopolymer technology. DSM's extensive materials expertise and broad industrial capabilities provide MediVas with a valuable partner in ...

American Oriental Bioengineering to Initiate a Phase One Clinical Trial in the United States of AOBO-001 Oral Capsule

... health through the development, manufacture and commercialization of a broad range of prescription and over the counter ("OTC") products, announced ... health through the development, manufacture and commercialization of a broad range of prescription and over the counter products. Statements ...

Intellect Neurosciences, Inc. Announces Independent Studies on Copper Binding Properties of its Lead Candidate OXIGON(TM)

... investigators. Also, it provides further support that OXIGON(TM) has broad potential for use in the treatment of other neurodegenerative conditions, ... and enters the brain, is an especially promising drug candidate with broad therapeutic potential." About Alzheimer's disease Alzheimer's ...

Novavax Announces Top Line Results of Phase IIa Clinical Trial for Its Seasonal Influenza VLP (Trivalent) Vaccine Candidate

... ways. First, it includes three viral proteins important for inducing a broad immune response including two surface proteins, hemmaglutinin ("HA") and ... clinical stage biotechnology company, creating novel vaccines to address a broad range of infectious diseases worldwide using advanced proprietary ...

New Data Show That Herceptin, Xeloda and Avastin Help Patients With Early and Advanced Breast Cancer Live Longer or Remain Disease Free for Longer

... or metastatic breast cancer, confirm that Avastin can be used with a broad range of chemotherapy treatments giving patients a median of almost ... diagnosis and treatment of diseases, the Group contributes on a broad range of fronts to improving people's health and quality of life. Roche is ...

Sangamo BioSciences Provides Update on Company's 2008 Progress and 2009 Objectives

... president and CEO of Sangamo. "We are successfully translating the broad applicability of our technology into opportunities for both novel human ... for Sangamo." Mr. Lanphier continued, "We are pursuing a broad development program for our lead ZFP Therapeutic(TM), SB-509, an activator ...

Lytix Presents LTX-109 Anti-Microbial Data at ICAAC

... these are important studies: "The fact that LTX-109 is effective against a broad range of pathogens highlights its potential utility as a truly novel broad spectrum antimicrobial drug. Indeed it is so effective, that although the ...

Novexel's NXL104/ceftazidime Combination Commences Phase II Clinical Trial in Hospital Patients With Complicated Urinary Tract Infections

... that its most advanced injectable antibacterial, which combines Novexel's broad spectrum beta-lactamase inhibitor, NXL104, with the well established ... regimen with Forest's ceftaroline, a novel, bactericidal injectable broad spectrum cephalosporin being developed as a therapeutic agent for the ...

Topical Treatment for Cold Sores Achieves Efficacy of Oral Drugs; Represents Paradigm Shift in the Treatment of Skin Infections

... for first-line treatment with the potential for widespread use across a broad range of patients," said Mary Flack, M.D., vice president of clinical ... for herpes labialis (cold sores), onychomycosis (nail fungus), acne and a broad platform of mucosal vaccines. The company's headquarters and laboratory ...

Paratek Reports Positive Phase 2 Clinical Data on its New Antibiotic PTK 0796 in Late Breaker Presentation at the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy

... in context with previous findings showing activity of PTK 0796 against a broad spectrum of drug resistant bacteria, including MRSA. Overall, the Phase 2 ... oral and IV MRSA-active compound in development with a spectrum broad enough for single agent treatment of cSSSI and CAP. These attributes have ...