ORBIS and Alcon Call Attention to the Aging Eye

... three-quarters of them could have avoided their blindness if they had been properly diagnosed or treated. ... States on the need to eliminate avoidable blindness in developing countries. "While 71 percent of ... healthcare technology to alleviate preventable blindness is not being fulfilled, and millions ...

Gene Therapy Provides Vision to People who Were Nearly Blind

... Trial Supported by the Foundation Fighting blindness are Published in the New England Journal ... in the 37-year history of the Foundation Fighting blindness and the entire history of retinal degenerative ... therapies and treatments that will reverse blindness in people with a variety of retinal degenerative ...

Paloma Pharmaceuticals Presents at the Association for Research in Vision and Ophthalmology 2009 Meeting

... following trauma or as part of certain diseases of the eye resulting in blindness in the affected area. In some cases, blindness or other visual deficits may be permanent, and related to the death of ...

Lions Eye Institute for Transplant & Research, Inc. Launches Multi-Million Dollar, State-of-the-Art Research Institute that Will Advance the Study of Blinding Eye Diseases

... upwards of 3 million Americans, contributes to over 120,000 new cases of blindness each year and is the leading cause of blindness among African Americans. LEITR's initial research platforms will explore ...

Alimera Sciences' Iluvien(TM) Phase 3 Studies for DME Pass Final DSMB Review Prior to October Readout

... diabetic retinopathy causes approximately 12,000 to 24,000 new cases of blindness each year, making diabetes the leading cause of new cases of blindness in adults aged 20 to 74. Based on published data, Alimera estimates that ...

DSMB Again Supports Continuation of Alimera Sciences' Phase 3 Clinical Trial of Iluvien(TM) for the Treatment of DME

... diabetic retinopathy causes approximately 12,000 to 24,000 new cases of blindness each year, making diabetes the leading cause of new cases of blindness in adults aged 20 to 74. Based on published data, Alimera estimates that ...

Gene Therapy Improves Vision in Patients with Congenital Retinal Disease

... It usually begins stealing sight in early childhood and causes total blindness during a patient's twenties or thirties. Currently, there is no treatment ... and Maguire were part of a team which reported successfully reversing blindness using gene therapy on dogs affected by the same naturally occurring form ...

ThromboGenics Completes Patient Enrolment in the Phase IIb Trial of Microplasmin in Vitrectomy (MIVI III)

... macular degeneration (AMD). Diabetic retinopathy is the leading cause of blindness among working-age adults, while AMD is the leading cause of blindness among the elderly. About ThromboGenics ThromboGenics is a ...

5-Year Study Published in Diabetologia Demonstrated Long-Term Safety of Lantus(R) Compared to NPH

... in the two treatment groups. This is the longest controlled study ever reported using insulin glargine. Diabetic retinopathy is a major cause of blindness in patients with diabetes. It is a progressive disease that results from cellular proliferation within the eye. The stimulation of IGF1 receptors is ...

Potentia Pharmaceuticals' POT-4 Drug Candidate for Age-Related Macular Degeneration Successfully Completes Phase I Clinical Trial - Prepares for Phase II

... on this mechanism of action, POT-4 holds the potential to be effective against both dry and wet AMD. About AMD AMD is the leading cause of blindness in the elderly of the western world and affects more than 10 million patients in the United States alone. The current standard of care for AMD relies ...

Lake Hospital System Receives $60,000 Grant for Groundbreaking Music Therapy Study

... blood glucose, blood pressure and blood lipids have decreased occurrence of serious complications, including cardiovascular disease, kidney damage, blindness and lower limb amputations," explained Martin L. Mandel, M.D., F.A.C.E., a Lake Hospital System endocrinologist who is serving as the study's medical ...

ThromboGenics Completes Patient Enrolment for Phase II Trial of Microplasmin for the Treatment of Diabetic Macular Edema (MIVI II DME)

... 6 months follow-up, and to be presented towards the end of 2009. Diabetic retinopathy is a major cause of visual loss and the leading cause of blindness in patients aged 20-60. Diabetic Macular Edema (DME) is a condition where swelling of the retina occurs in patients with diabetic retinopathy, due to ...

ESBATech's Antibody Fragment Enters Phase Ib/IIa in Ophthalmology

... changes in the lens structure. Cataracts are the leading cause of vision loss in adults that are 55 and older and are the leading cause of blindness worldwide. By age 65, about half of the human population has a cataract, and by age 75, almost everyone has a cataract. Surgery is the only effective ...

Durezol(TM) in the Treatment of Uveitis and Ganciclovir in the Treatment of Herpetic Keratitis: Studies of Treatments for Leading Causes of Blindness to Be Presented

... available in Europe for the treatment of ocular viral infections for more than 10 years. Herpes simplex keratitis is the leading cause of corneal blindness in the US, with 20,000 new primary cases of diagnosed each year and an additional 28,000 cases of recurrence each year. The risk of ...

Sirion Therapeutics Announces Positive Pivotal Uveitis Data for Durezol(TM)

... of the middle three layers of the eye: iris, choroid, and ciliary body. In the US it is responsible for an estimated 30,000 new cases of legal blindness each year and up to 15% of all cases of blindness. It affects 0.2% of the population in industrial nations, with as much as 10 times that prevalence ...

Potentia Pharmaceuticals Announces Positive Safety Data and Study Expansion in Phase I Trial for Lead Drug Candidate POT-4

... information gained from the extension of the study, to the initiation of Phase II trials in the future." About AMD AMD is the leading cause of blindness in the elderly of the western world and affects more than 10 million patients in the United States alone. The current standard of care for AMD relies ...

Quark Pharmaceuticals Announces First RNAi Drug Candidate Having a Novel, Proprietary Structure Covered by Quark Intellectual Property

... Data Validates Neuroprotective Effect of Quark's New RNAi Product on Dying Retinal Ganglion Cells, a Cause of blindness in Glaucoma FREMONT, Calif., Sept. 25 /PRNewswire/ -- Quark Pharmaceuticals, Inc., a development-stage pharmaceutical company discovering and ...

FDA Grants Pediatric Exclusivity for TOPAMAX(R), Extending the Marketing Exclusivity by Six Months

... and increased eye pressure (glaucoma). Call your doctor immediately if you have any decrease in vision or eye pain. These problems can lead to blindness if not treated right away. More common side effects are tingling in arms and legs, loss of appetite, tiredness, nausea, diarrhea, taste change and ...

'Snapshots' of Eyes Could Serve as Early Warning of Diabetes or Diabetic Eye Disease, U-M Researchers Report

... 4.1 million people over the age of 40 suffer from diabetic retinopathy, an eye-related complication of diabetes that is the leading cause of blindness among working-age adults. Twelve individuals in the study were known to have diabetic retinopathy, a disease in which blood vessels in the eye are ...

MultiVu Video Feed: Large, Long-Term Veterans Affairs Diabetes Trial (VADT) Reveals Important Cardiovascular Safety News on AVANDIA

... the benefits of long-term blood sugar control on other serious and potentially life-threatening complications of diabetes, such as kidney failure, blindness and amputation. VADT is an independent study sponsored by the Department of Veterans Affairs. SOUNDBITES: -- Dr. Farhad Zangeneh, MD, FACP, ...

Large, Long-Term Veterans Affairs Diabetes Trial (VADT) Reveals Important Cardiovascular Safety News on AVANDIA(R)

... the benefits of long-term blood sugar control on other serious and potentially life-threatening complications of diabetes, such as kidney failure, blindness and amputation." In VADT, the patient population was considered at higher risk for CV disease since more than 40% had prior CV events. Further, ...

Bayer and Regeneron Dose First Patient in Second Phase 3 Study for VEGF Trap-Eye in Wet Age-Related Macular Degeneration

... program evaluating VEGF Trap-Eye for the treatment of the neovascular form of Age-related Macular Degeneration (wet AMD), a leading cause of blindness in adults. VIEW 2 (VEGF Trap-Eye: Investigation of Efficacy and Safety in Wet AMD) will enroll approximately 1,200 patients in up to 200 centers in ...

MacuSight(TM) Announces Positive Preliminary Results From Phase 1 Study of Sirolimus in Wet Age-Related Macular Degeneration

... tasks including reading and driving. AMD occurs in both wet and dry forms, with the wet form accounting for the vast majority of cases of AMD-related blindness and progressing much more rapidly than dry. It is presently estimated that wet AMD affects approximately two million Americans. Growing at an ...

Ellex 2RT Study Demonstrates Clinical Efficacy in Treatment of Diabetic Macular Edema

... the central retina. This results in a deterioration of sight over time. ABOUT DIABETIC RETINOPATHY Diabetic retinopathy is the leading cause of blindness in American and European adults. It is caused by changes in the blood vessels of the retina. The U.S. Food and Drug Administration estimates that ...

Enrollment Complete in Pivotal Phase 3 Trial of Medidur(TM) FA for Diabetic Macular Edema

... said pSivida Limited Managing Director, Dr Paul Ashton. Diabetic retinopathy (DR), a complication of diabetes mellitus, is the leading cause of blindness in the working-age population of developed countries. At any time during progression of diabetic retinopathy, patients can develop DME which involves ...

Nastech Pharmaceutical Company Announces Initiation of Phase 2 Clinical Trial for Insulin Nasal Spray to Treat Diabetes

... Type 2 diabetes accounts for an estimated 90 to 95 percent of all cases. Complications can include cardiovascular disease, kidney disease, blindness and diseases of the central nervous system. Injectable insulin has been used to treat diabetes since the early 1920s and continues to be the ...

VEGF Trap-Eye Phase 2 Wet AMD Results Reported at ARVO Annual Meeting

... blindness. Wet AMD is the leading cause of blindness for people over the age of 65 in the U.S. and ... spots in central vision, and it can account for blindness in wet AMD patients. About DME Diabetic ... vessels of the retina. A leading cause of blindness in younger adults (under 50), DME occurs when ...

Positive Interim Phase 2 Data Reported for VEGF Trap-Eye in Age-Related Macular Degeneration

... 90% of AMD-related blindness. Wet AMD is the leading cause of blindness for people over the age of 65 in the U.S. and Europe. Macular ... of the retina creating blind spots in central vision and can account for blindness in wet AMD patients. About Regeneron Pharmaceuticals Regeneron is a ...

Insmed Inc. Welcomes Studies Linking IGFBP-3 to Prevention of Blindness in Premature Infants

... growth factor binding protein-3 (IGFBP-3) in the prevention of blindness among premature infants. IGFBP-3 is a key component of Insmed's lead drug ... development of the small blood vessels in the back of the eye, leading to blindness in severe cases. A Phase I clinical study investigating IPLEX(TM) as a ...

Lux Biosciences' Investigational Therapy for Uveitis, LX211, is Subject of Two Presentations at Key Ophthalmology Meeting, ARVO 2007

... and under-recognized medical condition that causes vision impairment, ocular pain, and loss of vision. Experts estimate that 10% of new U.S. cases of blindness result from this disease. Approximately 300,000 people suffer from uveitis in the United States alone, the majority of whom are affected by anterior ...

Sirion Therapeutics Receives Orphan Drug Designation for Ophthalmic Drug to Treat Viral Eye Infection

... product has the potential to advance medical treatment of herpes simplex keratitis in the U.S. Herpes simplex keratitis is a leading cause of corneal blindness in the United States." According to data published in the journal Archives of Ophthalmology, herpes simplex keratitis affects ...

Breaking Multi-Center Study: Masimo SET Pulse Oximetry Technology Shown to Significantly Lower Instances of Severe Retinopathy of Prematurity in Extremely Low Birth Weight Infants

... low birth weight (ELBW) infants developing retinopathy of prematurity (ROP) by 40%.(1) One of the most common causes of visual impairment and blindness in premature infants, ROP has been shown to be exacerbated by hyperoxia caused by the excessively high levels of supplemental oxygen often used to ...

Vision Deficit in Retinitis Pigmentosa Mice Corrected with DNA Nanoparticles

... of Oklahoma and the Foundation Fighting blindness Copernicus Therapeutics, Inc., a privately held ... The urgent mission of the Foundation Fighting blindness is to drive the research that will provide ... President Public Affairs OR Foundation Fighting blindness David Harrison, 410-804-1728 Media Contact ...