Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology
... for the development of novel genetically modified animal
models of human disease. ZFN technology will ... stem cells and allows rapid creation of new animal
In the study published in ... rats. The rat is a widely used laboratory animal
with a well characterized immune system, a nearly ...
Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM)
... marketing of proprietary products for human and animal
health markets worldwide. The fully-integrated ... and has three operating divisions: Human Health, animal
Health, and Food Safety. The Company's primary ... by revenues from marketed products in human and animal
health. Bioniche has been named one of the Top 50 ...
Alfacell Provides Shareholder Update
... Champions Biotechnology, to conduct a series of animal
studies on immune deficient mice to see what ... in cell lines are complemented by most recent animal
study in mice bearing tumors of varying sensitivity to Cisplatin and Carbo Platinum. In all of the animal
models, the addition of Onconase to Cisplatin ...
China Animal Welfare Law Under Review While 36,000 Dogs Culled
... city has sent out dog-beating squads to kill any animal
spotted on the street, stray or owned.
According to the International Fund for animal
Welfare's (IFAW - www.ifaw.org ) Asia Regional ...
Currently, China does not have any type of animal
welfare law in place, which means that there is ...
EUCODIS Bioscience Achieves Development Milestone in Second Collaboration With Lohmann Animal Health
... development of an undisclosed protein
for Lohmann animal
Health (LAH), a leading provider of feed ...
About Lohmann animal
Health (LAH) is a leading provider of feed ...
Isis Highlights New Data on Antisense Drugs to Treat Type 2 Diabetes and Obesity at ADA Scientific Sessions
... reduction in blood glucose levels in multiple animal
species. Isis and its collaborators also ... with good safety and tolerability in multiple animal
models including non-human primates. ... to a number of metabolic targets in a variety of animal
species that reduced mRNA target levels in ...
New Research Shows Nutrition 21's Chromium Histidinate Improves Markers for Mood and Carbohydrate Cravings
... U.S.D.A. animal
Studies: Chromium Picolinate and Chromium ... study testing its chromium histidinate in animal
models of obesity and of diabetes. The addition ... are safe and does not cause kidney dysfunction in animal
models of obesity and of diabetes.
Autism Studies Presented at Mid-Atlantic Research Consortium Meeting
... and behavior, then focus on subgroups of ASDs in animal
models. Scientists will then translate those ... Krieger Institute, presented the results of animal
studies that shed light on how autism operates in ... and increased repetitive behaviors. The changed animal
behaviors, said Blue, shared similarities with ...
Elusys' Anthrax Anti-Toxin, Anthim(TM), Enters Second Phase I Clinical Study
... efficacy in treating anthrax infection in animal
models and is a strong candidate for addition to ... reported the results of a previously conducted animal
efficacy study. A single dose of Anthim provided ... many hours after anthrax exposure. In earlier animal
studies, Anthim provided 100 percent protection ...
NovaBay Pharmaceuticals Announces Lead Anti-infective Product Candidate, NVC-422, Shown to be Effective in Treating Topical Fungal Infection
... resistance, today announced preclinical animal
data showing that NVC-422, the Company's lead ... dermatophyte based on an established animal
model previously used in the preclinical ... clinical and mycological efficacy rates in this animal
model compared to ciclopirox (Penlac(R)), a ...
Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs
... formation of cloned embryos using both human and animal
eggs, to-date, there has been no data indicating ... of human cells using eggs obtained from human and animal
sources, and shows for the first time that the ... data call into question the potential use of animal
egg sources to generate patient-specific stem ...
Human Genome Sciences Begins Delivery of First-in-Class Anthrax Treatment to U.S. Strategic National Stockpile
... 2007, HGS announced that the results of two animal
studies demonstrated the life-saving potential of ... findings demonstrated a survival benefit in two animal
species, which is the requirement for ... with the results of previous studies in multiple animal
models, which demonstrated that a single dose of ...
In Vivo Data on Taligen Therapeutics' Pipeline Candidates Presented at the XXII International Complement Workshop
... highlighted the candidates' efficacy in
models of complement-mediated diseases.
"These ... product candidates and test them
in a variety of animal
models as a precursor to their ... of modulation of the complement system on animal
models of human
disease," said Steve Tomlinson, ...
deCODE Files IND for DG071, a Novel PDE4 Modulator Being Developed for Alzheimer's and Other Cognitive Disorders
... which neural signaling is
reduced or impaired. In animal
models, DG071 has been shown to
significantly ... of the enzyme. DG071 has been shown in
models to potently and specifically improve ... with cAMP. DG071 has been shown in animal
models to improve
cognitive function with benefit ...
Data from In Vivo Disease Models on Taligen Therapeutics' Pipeline Candidates to be Presented at the XXII International Complement Workshop
... Presentations Include Proof-of-Concept animal
Data on Previously
Disclosed Fusion Protein TT30 ... protein TT32 and a monoclonal antibody mAb171, in animal
highlighted below. These data further ... T. Huber, V. Michael
Oct. 1, 2008, animal
models (Room: Montreal), 9:30 a.m. - 9:45 ...
PharmAthene Presents Data for Protexia(R) and Valortim(R) at 2008 BARDA Industry Conference / PHEMCE Stakeholders Workshop
... -- A study of Valortim(R) in a primate animal
model utilizing the
African green monkey (AGM) ... survived.
"We are very excited about the animal
model data from the AGM study,
which showed over ... and Valortim(R) constitute
studies. Significant additional non-clinical ...
InVitria Showcases Cell Culture Productivity Enhancers at BioProcess International
... ), a leading global supplier of animal
products that enhance productivity, safety ... consistent results.
Our customers have asked for animal
free products and products that improve
their ... )
InVitria has developed animal
free cell culture ingredients that
Data Suggest CEL-SCI's CEL-2000 Vaccine Prevents or Retards Permanent Damage of Rheumatoid Arthritis
caused by rheumatoid arthritis in an animal
model of the disease. These new
findings further ... that were conducted in a well established animal
rheumatoid arthritis. Enbrel is a ... arthritis treatments. Data collected in the animal
conducted with CEL-2000 demonstrate it is ...
Rapid Test for Pathogens Developed By K-State Researchers Could Be Used to Detect Diseases Used By Bioterrorists
... most common antibiotics used to treat human and animal
caused by these pathogens.
When a ... developed the test because most
human and animal
infections are caused by a mixture of pathogens.
of Veterinary Medicine to detect animal
and zoonotic pathogens; zoonotic
pathogens can be ...
Video: Resveratrol-based Nutriceutical (Longevinex(R)) Induces Favorable Changes on Gene Expression in Mouse Heart At Doses 17-320 Times Lower Than Prior Studies
... Alone - Independent Laboratory animal
SAN DIMAS, Calif., July 30 /PRNewswire/ ... 17-320 fold lower than used in
To view the Multimedia News ... exert more demonstrable genomic effects.
studies employed the human equivalent of 1565, ...
Halozyme Therapeutics Announces Positive Findings With Pegylated Enzyme in Prostate Cancer Models
... the presentation of positive pre-clinical animal
for its pegylated-rHuPH20 enzyme ... This study utilized three widely accepted animal
xenograft PC3, xenograft Du145luc, ... concerning the safety and efficacy of PEGPH20 in animal
that involve risk and uncertainties that ...
New Research Provides Evidence that Tea May Improve Attention and Focus, Keep Brain Cells Healthy, & Influence Genetics in Cancer
... tea on brain functions in laboratory and animal
models for over a
decade, looked at animal
models of neurological diseases such ... the cells' DNA.
Human epidemiological and new animal
data from around the world
suggests that drinking ...
Anadys Pharmaceuticals Resumes Clinical Investigation of TLR7 Mechanism in HCV
and the results of completed 13-week GLP animal
toxicology studies, Anadys
has received clearance ... 13 weeks contrast with results from prior 13-week animal
studies that utilized daily dosing of ... of chronic
hepatitis C. In initial 13-week animal
toxicology studies of ANA975 dosed
The Foundation for Biomedical Research Announces Winners of the 7th Annual Michael E. DeBakey Journalism Awards
... demonstrating the essential
role of humane animal
research in medical discoveries and ... that discusses the essential role
of humane animal
research in medical discoveries and ... if we are to advance medical science. All animal
research -- that
I know of, in any institution ...
Dr. Peter Nash, Ph.D. Joins Mach One Corporation as Chief Scientist
... a manufacturer and distributor of products
health, announced today the appointment of Dr. ... experience
in antibody production for animal
use which will help commercially expand
our unique product set for distribution into our targeted animal
On his new appointment, Dr. Nash ...
Pew Commission Says Industrial Scale Farm Animal Production Poses 'Unacceptable' Risks to Public Health, Environment
... -- The current industrial
production (IFAP) system often poses unacceptable ... by the Pew
Commission on Industrial Farm animal
Production (PCIFAP), in a study
released ... and must start now. And while some
areas of animal
agriculture have recognized these threats and ...
Additive Anti-Tumor Activity of NKTR-102 in Combination With Bevacizumab Highlighted in Positive Preclinical Data Presented at AACR Meeting
... of NKTR-102, as compared to irinotecan in animal
NKTR-102 is a PEGylated form of ... comparable doses of irinotecan.
models, NKTR-102 had a markedly improved safety ... profile when compared to irinotecan in animal
models. Both the
incidence and severity of ...
Nuvelo Announces Preclinical Data for NU206 Demonstrating Potent Therapeutic Activity in Oral Mucositis Models
... epithelial cell function
as demonstrated in early animal
studies. Preclinical studies suggest it can
promote growth and repair in animal
models of radiation or cancer
chemotherapy induced gastrointestinal injury, as well as in animal
of inflammatory bowel disease.
Increasing Dairy Milk Production with Electrolyzed Drinking Water
... explained Dr. James
Ferguson, Chief of animal
Production Systems, Department of ... are showing promising results at improving animal
shows signs of improved animal
health and production. EAU uses terms ...
Summit VetPharm has Identified Two Instances of Diverted Vectra 3D(TM)
... diversion of flea and
tick as well as other animal
health products. Fellow practitioners ... a purchase of Vectra 3D, we can keep companion animal
where it belongs -- in the hands ... from the
following distributors: NLS animal
Health, a division of Henry Schein Inc,
Anadys Pharmaceuticals Announces Positive Results for ANA598 in Animal Model of Chronic Hepatitis C Virus Infection
... and 2.6 log10 in the individual
animals. In one animal
the viral load reduction was sustained throughout
the remaining dosing period, while in the second animal
a modest rise in
viral load was seen over days 3 ... was within the baseline variability seen in this animal
In a previous study conducted ...
New Approach to Treating Anthrax Significantly Improves Survival Rates in Pivotal Efficacy Studies
... findings demonstrate a survival benefit in two animal
which is the requirement for ... with the results of previous studies in
models, which demonstrated that a single dose of ... ABthrax in multiple therapeutic
and prophylactic animal
models of inhalational anthrax," said James ...
Access Pharmaceuticals Demonstrates Ability to Significantly Reduce Glucose Levels in Pre-clinical Testing of Cobalamin(TM) Oral Insulin
significantly reduce glucose levels in an animal
model of diabetes, through
its oral insulin ... in the
gastrointestinal tract, were tested in an animal
model of diabetes.
Additional pre-clinical ... we are
excited by these promising results in an animal
model," added Stephen R.
Seiler, Access' ...
Spectrum Pharmaceuticals Announces Presentation of SPI-1620 Data at the AACR-NCI-EORTC International Conference
... vessels to overcome these problems. In animal
models, SPI-1620 caused a selective and transient ... cyclophosphamide, and 5-FU has been shown in animal
Furthermore, SPI-1620 enhanced the ... safe or effective,
that results of pre-clinical animal
studies do not necessarily predict the
results of ...
Man's Best Friend May Open Door to Understanding Fibrotic Lung Disease in Human and Animal Populations
... in the United States and the United
and human researchers are collaborating to find ... together thought leaders on both the human and animal
of fibrotic lung disease as a ... Kennel Club
Canine Health Foundation and Morris animal
Similarities between human fibrotic ...
Positive Results for NKTR-118 (oral PEG-naloxol) Presented at American Academy of Pain Management Meeting
... oral NKTR-118
improved GI transit time in an animal
model of morphine-induced
constipation, while ... the
ability to improve GI transit time in an animal
model of morphine-induced
constipation, while ... safety and
pharmacokinetic profile in an animal
model. About NKTR-118 NKTR-118 is an oral drug ...
Feeling Anxious or Distracted? New Research Shows a Cup of Tea Could Help
... the cells' DNA. Human epidemiological and new animal
data from around the world suggest
that drinking ... of tea on brain functions
in laboratory and animal
models for over a decade. Her most recent studies,
presented at the symposium, looked at animal
models of neurological
diseases such as ...
K-State Researchers Bringing Expertise to Kansas City Symposium on Disease and National Security
... the U.S.
Department of Agriculture's National animal
Disease Center and is an
adjunct professor with ... of medical schools, research institutes, and animal
and nutrition companies located within the Kansas City animal
Corridor, we can boast of a level of ...
WorldHeart Announces Further Milestone in Miniaturized Assist Pump Development
... successful completion of the first
study of a miniaturized, pediatric, ventricular ... for earlier-stage heart failure patients. The animal
implant was performed by Peter Wearden, M.D., ... experiments, we are
encouraged to begin 30-day animal
implants, focusing again on pump
performance and ...
Cytokine Demonstrates Oral Efficacy of Small-Molecule MIF Inhibitors
... inhibitors showed oral efficacy in animal
models. Based on these
results, the Company ... compounds were recently shown to be effective in animal
multiple sclerosis (MS) and arthritis when administered orally. The MS animal
experiments were conducted in the laboratories of ...