Access Pharmaceuticals Provides Update on ProLindac Clinical Development Program
... novel DACH platinum drug that has shown to be active
in many solid tumors in human clinical studies. ... cancer trial that showed that ProLindac was more active
than currently available platinum drugs in that ... a novel DACH platinum drug that has shown to be active
in many solid tumors in human clinical studies. ...
Human Genome Sciences and GlaxoSmithKline Announce Positive Phase 3 Study Results for BENLYSTA(TM) in Systemic Lupus Erythematosus
... Phase 3 trials in patients with serologically active
systemic lupus erythematosus (SLE). In the ... the findings that emerged in the serologically active
subgroup of SLE patients at Week 52 in our Phase ... placebo plus standard of care, in serologically active
(i.e., autoantibody-positive) patients with SLE. ...
Iontophoretic Drug Delivery System (IDDS) Containing Lidocaine and Epinephrine is Effective in Reducing Pain Associated With Insertion of an Intravenous Catheter in a Phase 2 Clinical Trial
... Exchange Limited) announced that its improved active
transdermal delivery technology, which ... the venipuncture procedure were 16.4 mm for the active
treatment versus 24.0 mm for the Placebo ... statistically lower VAS scores for the active
group as compared to the Placebo group. In ...
Procter & Gamble Pharmaceuticals Launches Asacol(R) HD (mesalamine) Delayed-Release Tablets
... are indicated for the treatment of moderately active
ulcerative colitis (UC), a form of inflammatory ... followed by periods of remission. Moderately active
UC is characterized by tougher symptoms than mildly active
UC. Asacol HD is proven to help treat these ...
Landmark Study for GSK's Cervical Cancer Vaccine Published in The Lancet
... to represent general population of sexually active
TVC-naive included all women ... risk of HPV infection throughout their sexually active
lives. Approximately 100 types of HPV have been ... and a leader in innovation. The company is active
in the fields of vaccine research, development ...
SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
... therapy for the treatment of moderate-to-severe, active
rheumatoid arthritis (RA), active
and progressive psoriatic arthritis (PsA) and severe, active
ankylosing spondylitis (AS).
CeNeRx BioPharma Obtains Rights to Novel Drug Candidate for Prevention and Treatment of Neurodegeneration Disorders
... --Orally active
Enhancer of Human Nerve Growth Factor Has ... candidate, CXB909, is a small molecule, orally active
agent that enhances the effects of nerve growth ... also includes CXB909, a small molecule, orally active
agent for the prevention and treatment of ...
New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients
... of patients with moderately to severely active
rheumatoid arthritis (RA) who had prior treatment ... news for patients with moderately to severely active
rheumatoid arthritis who have been previously ... anti-TNFs. The trial included 461 patients with active
RA of 8.65 years mean duration. Discontinuation ...
Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis
... L onal Antibody (GO-REVEAL) study, patients with active
PsA were randomized to placebo (n=113), SIMPONI ... with at least 3 swollen and tender joints and active
psoriatic skin lesions of at least two cm in ...
The GO-RAISE trial included 356 patients with active
ankylosing spondylitis. Patients were randomized ...
Paclitaxel Poliglumex (OPAXIO(TM)) Added to Cisplatin and Radiation Produces 45% Pathologic Complete Remissions in Patients With Esophageal Cancer
... that paclitaxel poliglumex may be a uniquely active
and selective radiosensitizing therapeutic. Most ... tumor tissue with continual slow release of the active
agent, paclitaxel," noted Jack Singer, M.D., ... chemotherapeutic that links paclitaxel, the active
ingredient in Taxol(R), to a biodegradable ...
New One-Year Data from REMICADE(R) SONIC Trial Show Sustained Efficacy Compared with Azathioprine in Treatment of Crohn's Disease
... 3b study of patients with moderately to severely active
Crohn's disease having inadequate response to ... FDA for the treatment of moderately to severely active
Crohn's disease for the reduction of the signs ... FDA for the treatment of moderately to severely active
ulcerative colitis, in patients with an ...
New Study Evaluating the ADHD Medication VYVANSE(R) (lisdexamfetamine dimesylate) CII Demonstrated No Change in the Pharmacokinetic Profile of VYVANSE When Coadministered with Prilosec OTC(R) 40 mg (20 mg X 2), a Commonly Used Proton Pump Inhibitor (PPI)
... maximum plasma concentrations of amphetamine, the active
medication. Other pharmacokinetic parameters ... plasma concentration and area under curve) of active
medication were not altered for either VYVANSE or ... "In this study, the conversion of VYVANSE to its active
form was not affected when coadministered with ...
Medarex Announces Primary Endpoint Achieved in MDX-1100 Anti-IP-10 Antibody Phase 2 Trial for Rheumatoid Arthritis
... Phase 2 proof-of-concept trial in patients with active
rheumatoid arthritis (RA) receiving methotrexate ... Phase 2 study in RA enrolled 70 patients with active
disease while on methotrexate. Patients in the ... placebo-controlled study in patients with active
UC while continuing standard UC therapy is ...
Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)
... option for adults with moderately to severely active
rheumatoid arthritis and moderate to severe ... option for adults with moderately to severely active
rheumatoid arthritis. Cimzia(R) is also approved ... in adult patients with moderate to severely active
disease who have had an inadequate response to ...
FDA Approves Vanda Pharmaceuticals' Fanapt(TM) for the Treatment of Schizophrenia
... studies comparing Fanapt(TM) to placebo and active
control in patients with schizophrenia, as well ... Fanapt(TM) (24 mg/day) compared to placebo and an active
control (Geodon(R)), the 24 mg/day Fanapt(TM) ... and 20-24 mg/day) compared to placebo and an active
control (Risperdal(R)), both doses of Fanapt(TM) ...
Two-Year Phase III Data Presented at AAN 61st Annual Meeting Show Positive Outcome of Cladribine Tablets in Patients With Multiple Sclerosis
... reduction of at least 70% in the mean number of active
T1 gadolinium-enhanced lesions per subject per scan, the mean number of active
T2 lesions per subject per scan, as well as the ... ON To Rebif New Formulation in Patients With active
Relapsing Disease) study: a Phase II ...
Clinician Reports Fast Healing of Intractable Wounds Using MEDIHONEY(R)
... at the SAWC include:
Leptospermum Honey - A Debriding ... Baylor Health Care System, TX)
Use of active
Leptospermum Honey Dressings in the Home ... (Tim Larson, Cleveland Clinic, OH)
Leptospermum Honey: Treatment for Various ...
Data Presented at AUA Demonstrate PROVENGE Significantly Prolongs Survival for Men With Advanced Prostate Cancer in Pivotal Phase 3 IMPACT Study
... by 38 Percent Compared to Placebo -
- First active
Cellular Immunotherapy for Cancer to Prolong ... cancer and represents the first in a new class of active
cellular immunotherapies (ACI) specifically ... and validate the potential of our pipeline of active
cellular immunotherapy product candidates that ...
AUA Guideline: Full Kidney Removal Not Necessary for All Kidney Tumors
... such as partial nephrectomy, thermal ablation and active
surveillance, minimize these risks and are viable ... for the patient at high surgical risk who wants active
treatment and accepts the need for long-term ... the current thermal ablation literature.
Men Treated for Localized Prostate Cancer Could Benefit From Pomegranate Juice Consumption
... daily. Currently, in the sixth year of treatment, active
patients who remain on the study have a median ... 0.06 to 0.024.
Researchers compared active
patients, who remain on the study, with ... the decline in median PSA slope were greater in active
patients when compared to non-active patients.
Micromet Presents Preclinical Data Showing Activity of Erbitux and Vectibix Based BiTE Antibodies against KRAS- and BRAF-mutated Human Colorectal Cancer Cells
... and Vectibix(R) (panitumumab) they were highly active
against KRAS-and BRAF-mutated human colorectal ... cetuximab(2,3) and panitumumab(3,4) are not active
in colorectal cancer patients with tumor cells ... a relevant non-human primate species suggest that active
serum levels of the cetuximab-based BiTE antibody ...
March 2009 Mayo Clinic Health Letter Highlights Knee Repair Surgery, Anxiety Disorder and Preventing Blood Clots
... information, 800-333-9037, extension 9771.
at 50? Still Prime for Knee Repair Surgery
... knee injury, doesn't have to permanently sideline active
adults age 50 and older, according to the March ...
More people 50 and older are leading active
lives, which makes them good candidates for ...
Acanya(TM) Gel, a New Treatment for Moderate to Severe Acne, Launched by Coria Laboratories
... efficacy to the vehicle gel and either individual active
ingredient, while demonstrating excellent ... were <1 (1=mild) and comparable to individual active
ingredients and vehicle.
Patient ... efficacy to the vehicle gel and either individual active
ingredient, while demonstrating excellent ...
New Study First to Confirm Sandostatin LAR(R) Depot Controls Tumor Growth in Patients With Rare Gastrointestinal Tumors
... options and had tumors that were functionally active
(i.e., tumors that secrete various hormones and ... a disease caused by a pituitary adenoma.
ingredient in Sandostatin LAR, octreotide ... and 600,000 patient years of experience, the active
ingredient in Sandostatin LAR has achieved a ...
Positive Phase II Study of Pacira's EXPAREL(TM) (DepoBupivacaine) in Hernia Repair Presented at the Postgraduate Assembly in Anesthesiology (PGA)
... activity in EXPAREL treated
patients compared to active
-- A positive trend toward lower opioid use in all EXPAREL groups compared
-- More patients who received EXPAREL avoided opioids altogether, compared
In addition, the study ...
Keryx Biopharmaceuticals, Inc. Reports Phase 1/2 Data on KRX-0401 (Perifosine) at 50th Annual Meeting of American Society of Hematology
... with 84 patients, of which 24 remain on active
treatment. In his presentation, Dr. Richardson ... stated, "Perifosine appears to be particularly active
with durable responses when combined with ... reached at 16.8 months. Ten patients remain on active
Abstract 1010: Final Results ...
Rib-X Pharmaceuticals Reports Positive Top-Line Results from Phase 2 Study of Delafloxacin
... this trial, delafloxacin was shown to be the more active
compound overall, including its activity against ... is developing novel classes of antibiotics active
against multi-drug resistant Gram-negative ... is focused on developing an IV/oral macrolide active
against methicillin-resistant S. aureus, ...
Positive Phase II Study of Pacira's EXPAREL(TM) (DepoBupivacaine) in Total Knee Arthroplasty Presented at International College of Surgeons World Congress
... EXPAREL 300mg and 450mg patient groups versus active
control, 6.4 vs. 7.8 pain intensity and 6.1 vs. ... and vomiting occurrence was 40% lower than in the active
Approximately 8% of ... use versus zero percent (0%) of patients in the active
More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies
... adverse reactions in nursing infants. Sexually active
female patients taking Gleevec should use ... should not be used during pregnancy. Sexually active
female patients should use effective ... drugs.
Zometa contains the same active
ingredient as found in Reclast(R) (zoledronic ...
CHMP Recommends Approval of New Indication for Enbrel(R) as Treatment for Severe Psoriasis in Paediatric Patients
... indicated for the treatment of
moderate to severe active
rheumatoid arthritis in adults when the response ... is also indicated in the treatment of severe, active
progressive rheumatoid arthritis in adults ... idiopathic arthritis
Treatment of active
polyarticular juvenile idiopathic arthritis ...
Alba Therapeutics Announces Enrollment of Its First European Patient in Global Phase IIb Study of Larazotide Acetate for Treatment of Active Celiac Disease
... Marks the First Time a European Patient with active
Disease has Enrolled in a Clinical Trial ... regulator, for the treatment of
patients with active
celiac disease (CD). The global ... and tolerability of larazotide
acetate in 106 active
CD subjects adhering to a gluten-free diet, ...
Pivotal Data Showed SYMBICORT(R) Improved Lung Function in Adults with COPD
... (e.g., bronchitis)
was generally higher for all active
treatment groups, except SYMBICORT
80/4.5 mcg, ... (e.g., bronchitis)
was slightly higher in the active
treatment groups compared to placebo.(4)
-- The ... beta2-adrenergic agonist), one of the active
SYMBICORT is not ...
CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years
... with methotrexate (MTX) in the treatment of active
arthritis who did not adequately ... the prevention of joint damage in patients with active
Patients completing RAPID 1 through 52 weeks ... O11) phase III study, 220
adult patients with active
RA who had previously failed at least ...
Trius Antibiotics to be Highlighted in 18 Presentations at ICAAC/IDSA
... - 12:15 pm)
-- F1-2060: MICs of TR-700, the active
Moiety of the Novel Oxazolidinone Prodrug ... F1-2062: In Vitro Pharmacodynamics of TR-700, the active
Moiety of Prodrug TR-701, a Novel ... -- F1-2069: Relative Potency of TR-700, the active
Moiety of Prodrug TR-701, Against Selected ...
CIMZIA(R) (Certolizumab Pegol) Provides Long-Term Benefit Without Dose Escalation in Crohn's Disease Patients
... no new safety signals observed over 2.5 years of active
Pharmacoeconomics Study (Abstract ... in adult patients with moderate
to severe active
disease who have had an inadequate response ... receiving CIMZIA for signs and
symptoms of active
tuberculosis, including patients who tested ...
New Findings Show Efficacy of REMICADE(R) Compared With Azathioprine in Treatment of Crohn's Disease According to First-of-its Kind Study
... FDA for the treatment of moderately to severely active
for the reduction of the signs ... in patients with moderately to severely active
RA, when administered in combination with ... -- Reducing signs and symptoms in patients with active
AS. -- Reducing signs and symptoms and inducing ...
CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohn's Patients
... in adult patients with moderate
to severe active
disease who have an inadequate response to ... the intestinal mucosal lesions in patients
Crohn's disease. CIMZIA was administered ... in adult patients with moderate
to severe active
disease who have had an inadequate response ...
Dendreon Announces Interim Data From Phase 3 PROVENGE IMPACT Trial
... the safety and efficacy of the
cellular immunotherapy PROVENGE(R) (sipuleucel-T) ... reported in our previous trials).
Cellular Immunotherapy with PROVENGE
PROVENGE ... a
specific long-lasting response against cancer. active
immunotherapy holds promise because it ...
New Analyses Indicate that Divigel(R) (estradiol gel) 0.1% Is a Valuable Option for Certain Postmenopausal Women With Hot Flashes
... known or suspected
estrogen-dependent neoplasia; active
or history of deep vein thrombosis
(DVT) or pulmonary embolism; active
or recent arterial thromboembolic
disease; liver ... manufacturing and marketing of
pharmaceutical ingredients and diagnostic tests ...
QuatRx Pharmaceuticals Announces Additional Data From Phase 3 Study for Ophena(TM) (Ospemifene Tablets) Showing Improvements in Clinical Symptoms of Vulvovaginal Atrophy
... vaginal atrophy
symptoms among sexually active
and non-sexually active
women; results presented today ... for both sexually
active and non-sexually active
respondents. A majority of women in the