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Abuse in Medical Technology

Mayo Clinic Proceedings: A Comprehensive Review of Addiction to Prescription Painkillers Among Patients and Physicians

... tragedies, of prescription chemical addiction and abuse are being discussed, these articles offer crucial ... direction and optimism. Addiction to and abuse of prescription opioid drugs are prevalent, and ... have the greatest risk of opioid dependence and abuse among health care providers. Also in the ...

Acura and King Receive FDA Complete Response Letter Regarding Acurox(R)

... Letter raises issues regarding the potential abuse deterrent benefits of Acurox(R). Acura and King ... Technology, which is designed to deter misuse and abuse by intentional swallowing of excess quantities of ... product candidates and other innovative abuse deterrent technologies. Acura and King jointly ...

Classwide Opioids REMS: A Good Idea, Implement Carefully

... patients and non-patients, those who misuse or abuse the drug and are not prescribed the medication. ... Will drug abusers shift their abuse to other licit or illicit substances? ... chronic pain in the effort to prevent misuse and abuse of these important medications. It would be of ...

American Academy Of Orthopaedic Surgeons 2009 Annual Meeting 'Highlights and Hot Topics'

... Broken Bones as Indicators of Child abuse ( ... Seen Between Types of Orthopaedic Injury and abuse In a study of nearly 1,500 ... classified as either confirmed victims of child abuse or sufferers of accidental trauma, clear ...

FDA Approves Tapentadol Immediate-Release Tablets for Relief of Moderate to Severe Acute Pain

... increased risk of misuse, abuse, or diversion. abuse of tapentadol poses a risk of overdose and death. This risk is increased with concurrent abuse of tapentadol with alcohol and other substances. Monitor patients closely for signs of abuse and addiction. Tapentadol may impair ...

Alpharma Announces Positive Results From Pivotal Phase III Efficacy Trial on ALO-01 (EMBEDA(TM)) (morphine sulfate extended-release with sequestered naltrexone hydrochloride) Capsules at the American Academy of Pain Management Annual Clinical Meeting

... therapies.(2,3A) However, prescription opioid abuse has escalated along with increased legitimate use ... relief while minimizing the potential for misuse, abuse and diversion.(3B,7) Study Design The ... 3. Woolf CJ, Hashmi M. Use and abuse of opioid analgesics: potential methods to ...

REMOXY(R) NDA Filing Accepted by FDA and Priority Review Granted

... E. Brown, DVM, President and CEO of DURECT. "The abuse of pain medications is a widespread problem in ... with the added benefit of being less prone to abuse (e.g. by crushing or water extraction) than other ... superior clinical/commercial attributes such as abuse deterrence, improved convenience, compliance, ...

Catalyst Pharmaceutical Partners, Inc. Begins Enrollment for U.S. Phase II Clinical Trial of CPP-109 in Patients with Methamphetamine Addiction

... that affects the central nervous system. abuse of the drug leads to devastating ... treatment for methamphetamine and other stimulant abuse in 2006. In addition, according to the 2006 ... National Drug Control Policy, the costs of drug abuse to society were an estimated $180 billion in 2002 ...

Alpharma Presents Data Addressing Abuse Liability Features, Safety and Efficacy on ALO-01 (EMBEDA(TM)) (morphine sulfate extended-release with sequestered naltrexone hydrochloride) at the American Pain Society Annual Scientific Session

... clinically relevant features addressing abuse liability alongside a promising safety and ... of ALO-01 when crushed -- a common method of abuse -- among recreational drug users and when taken ... "The undertreatment of chronic pain and the abuse of prescription opioids are both serious health ...

Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain

... and a Schedule II controlled substance, with an abuse liability similar to other opioid analgesics. ... is concerned about an increased risk of misuse, abuse or diversion. Schedule II opioid substances which ... and methadone have the highest potential for abuse and risk of fatal overdose due to respiratory ...

SUNY Youth Sports Institute Convenes Top Experts in NYC Next Week to Present Research & Analysis on Energy Drink Health Impacts

... Institute, Philadelphia, PA, Associate Director, Center for Substance abuse Research, University of Maryland, College Park , MD. One of Dr. Arria's ... Institute, Philadelphia, PA Associate Director, Center for Substance abuse Research, University of Maryland, College Park , MD Christina ...

King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use

... triple-action combination of niacin and inactive ingredients reduces its abuse liability. About EMBEDA(TM) EMBEDA(TM) is an investigational ... and there is no evidence that the naltrexone in EMBEDA(TM) reduces the abuse liability of EMBEDA(TM). About King Pharmaceuticals, Inc. King, ...

Study of Cannabinoid Medicine for Pain Found Patients Got 'High,' but Effects Not Related to Pain Relief

... similar to smoking marijuana, leading researchers to conclude the abuse potential of this class should be studied further. Using the Addiction Research Center Inventory (ARCI), the gold-standard for determining the abuse liability of substances, Dr. Wasan and colleagues at McLean Hospital ...

Advances in Science and Treatment of Pain Presented at 25th Annual American Academy of Pain Medicine Meeting January 28 - 31, 2009

... and brain to effectively treat pain, including medications with decreased abuse potential." At this year's meeting, attendees will have access to ... Trauma/Combat Injury, Poster 273 Reduction of Opioid/Illicit Drug abuse & Electronic Prescription Monitoring, Poster 274 About ...

Novel Compound Shows Promise for Treatment of Alcoholism

... for the treatment of alcoholism. The National Institute on Alcohol abuse and Alcoholism (NIAAA) estimates 15.1 million people are alcohol-abusing ... by the State of California for Medical Research on Alcohol and Substance abuse and Department of Defense. Southern Research operates a successful drug ...

Discovering How Video Games Can Motivate Healthy Behaviors: More than $2 Million Awarded to 12 Research Teams Across U.S.

... patients progress faster in physical therapy to how people in substance abuse treatment can practice skills and behaviors in the virtual world of a game ... designed to enable people aged 18 to 65 that are diagnosed with alcohol abuse or dependence to practice skills that can help them prevent real-world ...

Public Forum to Discuss Addiction as a Treatable Disease and Highlight National Alcohol and Drug Addiction Recovery Month

... the national data on this growing public health problem -- the Substance abuse and Mental Health Services Administration (SAMHSA) reports that ... respiratory depression and death. SUBOXONE has potential for abuse and produces dependence of the opioid type with a milder withdrawal ...

Nabi Biopharmaceuticals Announces Continued Positive NicVAX Phase 2b Data at Nine Months

... smoking cessation researchers and the National Institute on Drug abuse (NIDA). Nabi will use these validated and promising nine-month data to ... that it received a $4.1 million grant from the National Institute on Drug abuse (NIDA), which is part of the National Institutes of Health. NIDA has also ...

New Study Presented at WorldSleep 2007 Demonstrates Ramelteon Has Sustained Efficacy Over Six Months in Adults With Chronic Insomnia

... first and only prescription sleep medication that has shown no evidence of abuse or dependence in clinical studies,* and has not been designated as a ... the sleep- wake cycle. *ROZEREM is not a controlled substance. A clinical abuse liability study showed no differences indicative of abuse potential ...

GAA Calls on Secretary Clinton to Speak Out Against Gender-Based Violence During Her Africa Trip

... African governments to address the scourge of violence," said Zeitz. Worldwide, one in three women will survive physical, sexual, or emotional abuse in her lifetime. One in five will survive rape or attempted rape, and around 50% of female sexual assault survivors are 15 years or younger at the ...

FDA Issues Complete Response Letter for INTUNIV(TM) (guanfacine) Extended Release for the Treatment of ADHD in Children and Adolescents

... of guanfacine, designed to provide steady delivery of drug throughout the day. INTUNIV is not a controlled substance and has no known potential for abuse or dependence. Guanfacine, the active ingredient in INTUNIV, is thought to work directly by binding selectively to alpha-2A adrenergic ...

PTSD Associated With Higher Alzheimer's/Dementia Risk; Moderate Alcohol Consumption May Lower it

... veterans without PTSD (HR = 1.8, 95% CI 1.7-1.9). Results were similar when they excluded those with a history of traumatic brain injury, substance abuse or depression. "It is critical to follow patients with PTSD, and evaluate them early for dementia," Yaffe said. "Further research is needed ...

Conatus Pharmaceuticals Initiates a Second Phase 2 Clinical Trial for the Treatment of Hepatitis

... and can be caused by many different conditions or "insults" to the liver including Hepatitis C and other viral infections, obesity, chronic alcohol abuse or autoimmune diseases. Conatus was founded by the executive management team of Idun Pharmaceuticals in July 2005 following the successful sale of ...

Blanchette Rockefeller Neurosciences Institute and Inverness Medical Innovations to Develop Commercial Test to Detect Early Alzheimer's Disease

... diagnostics, Inverness' products, as well as its new product development efforts, focus on infectious disease, cardiology, oncology, drugs of abuse and women's health. Inverness is headquartered in Waltham, Massachusetts. ...

New Phase 3 Study of Tapentadol Immediate Release Tablets Published in Current Medical Research and Opinion Journal

... is concerned about an increased risk of misuse and abuse. All patients treated with mu-opioid agonists require careful monitoring for signs of abuse and addition. NUCYNTA(TM) may be abused by crushing, chewing, snorting or injecting the product. These practices pose a significant risk to the ...

New Study Evaluating the ADHD Medication VYVANSE(R) (lisdexamfetamine dimesylate) CII Demonstrated No Change in the Pharmacokinetic Profile of VYVANSE When Coadministered with Prilosec OTC(R) 40 mg (20 mg X 2), a Commonly Used Proton Pump Inhibitor (PPI)

... Tell the doctor immediately if you or your child develops any of these conditions or symptoms while taking Vyvanse or Adderall XR. abuse of amphetamines may lead to dependence. Misuse of amphetamine may cause sudden death and serious cardiovascular adverse events. These events have ...

Shire Announces Study Results of the Effects of INTUNIV(TM) (Guanfacine) Extended Release on Secondary Measures in Children with ADHD and Oppositional Symptoms

... clinical trials, INTUNIV demonstrated significant reduction in ADHD symptoms. INTUNIV is not a controlled substance and has no known mechanism for abuse or dependence. Guanfacine, the active ingredient in INTUNIV, is thought to work directly by binding selectively to alpha-2A adrenergic receptors ...

One Step Closer: Novel Opioid Receptor Compound in Phase I Clinical Trials

... leading to Wentland's latest discovery was funded in 1999 through a $826,000 grant from the National Institutes of Health/National Institute on Drug abuse (NIH-NIDA) in an effort to discover novel drugs to treat cocaine abuse. In 2002, Wentland's NIH grant was renewed for an additional $1.6 million, and ...

DURECT Reports Positive Phase IIb Data from TRANSDU(TM)-Sufentanil Clinical Program

... oral, transdermal and injectable depot delivery technologies may enable new indications and superior clinical/commercial attributes such as abuse deterrence, improved convenience, compliance, efficacy and safety for small molecule and biologic drugs. For more information, please visit ...

Shire Withdraws European Application for DAYTRANA(TM) (Methylphenidate Transdermal System)

... or hostility. Tell the doctor immediately if you or your child develops any of these conditions or symptoms while taking Vyvanse. abuse of amphetamines may lead to dependence. Misuse of amphetamine may cause sudden death and serious cardiovascular adverse events. These events have ...

Premier Research Announces Milestone New Drug Application

... relief of moderate to severe pain. Acurox(R) utilizes Acura Pharmaceuticals' patented Aversion(R) Technology, which is designed to deter misuse and abuse by intentional swallowing of excess quantities of tablets, intravenous injection of dissolved tablets and nasal snorting of crushed tablets. ...

Study Shows Leconotide, an Investigative Calcium Channel Blocker, Has Potential as a Selective, Efficacious, Non-Opioid Pain Treatment

... are exciting for researchers in the field of pain medicine, doctors whom treat pain, and patients who suffer or are under-treated because of the abuse potential and side effects associated with opioid treatments," said Colin Goodchild, PhD, and director of the Centre for Pain Research and Palliative ...

Cara Therapeutics Initiates Phase II Proof-Of-Concept Trial of Novel Analgesic in Acute Post-Operative Pain

... in multiple species. In contrast to currently marketed opioids, CR845 did not produce inhibition of intestinal transit (ileus) or elicit signs of abuse or addiction liability in animal models. Preclinical studies also indicate that CR845 possesses anti-itch activity. About Cara Therapeutics ...

Recent Study Demonstrated VYVANSE(R) (lisdexamfetamine dimesylate) CII Provided Improvements in Behavior, Inattention, and Math Test Scores from 1.5 Hours up to 13 Hours following Administration in Children with ADHD

... or hostility. Tell the doctor immediately if you or your child develops any of these conditions or symptoms while taking Vyvanse. abuse of amphetamines may lead to dependence. Misuse of amphetamine may cause sudden death and serious cardiovascular adverse events. These events have ...

Inverness Medical Innovations Participates in Meeting on HIV/AIDS with UN Secretary-General

... diagnostics, Inverness' products, as well as its new product development efforts, focus on infectious disease, cardiology, oncology, drugs of abuse and women's health. Inverness is headquartered in Waltham, Massachusetts. For more information about Inverness Medical Innovations, please ...

Study Published in Journal of Clinical Psychiatry Showed Once-Daily VYVANSE(R) (lisdexamfetamine dimesylate) Significantly Improved ADHD Symptoms in One of the Largest Controlled Stimulant Trials in Adults with ADHD

... or hostility. Tell the doctor immediately if you or your child develops any of these conditions or symptoms while taking Vyvanse. abuse of amphetamines may lead to dependence. Misuse of amphetamine may cause sudden death and serious cardiovascular adverse events. These events have ...

Cephalon Receives Complete Response Letter Regarding Request for Expanded FENTORA Label for Non-Cancer Breakthrough Pain

... prescribed FENTORA are opioid-tolerant. Additionally, the company will continue to enhance its existing programs to mitigate risks associated with abuse and misuse. FENTORA is currently approved for the management of breakthrough pain in opioid-tolerant patients with cancer (for full prescribing ...

Pediatric Heart Transplants at Montefiore Approved by NY State Department of Health

... a key provider of community-based care through its network of 16 school-based clinics, the Child Advocacy Center for diagnosis and treatment of child abuse and neglect, a Safe House for lead poison prevention, mobile pediatric centers and other unique initiatives. ...

Inverness Medical Innovations Receives USDA Licensure of the BinaxNOW(R) Avian Influenza Virus Type A Antigen Test Kit

... diagnostics, Inverness' products, as well as its new product development efforts, focus on infectious disease, cardiology, oncology, drugs of abuse and women's health. Inverness is headquartered in Waltham, Massachusetts. For more information about Inverness Medical Innovations, please ...

ELADUR(TM) Development Update: DURECT Receives Orphan Drug Designation for Bupivacaine for Post-Herpetic Neuralgia

... proprietary oral, transdermal and injectable depot delivery technologies enable new indications and superior clinical/commercial attributes such as abuse deterrence, improved convenience, compliance, efficacy and safety for small molecule and biologic drugs. For more information, please visit ...
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(Date:9/15/2014)... million years after it formed may have been surprisingly ... and active crustal plates. , This alternate view of ... substantial new support from the first detailed comparison of ... ago with those formed contemporaneously in Iceland, which has ... Earth. , The study was conducted by a team ...
(Date:9/15/2014)... is no published account where hippopotamuses are demonstrably shown ... of water. But if they can,t swim, how did ... widely accepted models for the methods, patterns, and timing ... Cyprus, Crete, and Madagascar) may need to be reconsidered. ... the mainland are not currently supported by positive ...
(Date:9/15/2014)... the proteins in our cells cooperate with one another. ... of thousands of different proteins find the correct dancing ... body, brain and nervous system. A recent breakthrough at ... down the door and provided a look at the ... Professor emeritus Jens Jrgen Led of the University of ...
Breaking Biology News(10 mins):Early Earth less hellish than previously thought 2Early Earth less hellish than previously thought 3Protein courtship revealed through chemist's lens 2Protein courtship revealed through chemist's lens 3
(Date:9/15/2014)... DALLAS, TX September 12, 2014 - An estimated ... disorder (PTSD) at some point during their lifetime. Brought ... PTSD is the result of altered chemistry and physiology ... a normal brain versus one altered by PTSD is ... from the Center for BrainHealth at The University of ...
(Date:9/15/2014)... 2014 The White House has recently ... offenders in jail and prison and toward helping them ... as a positive change. , The nation is currently ... abuse. According to an article from The Washington ... a shift away from using the criminal justice system ...
(Date:9/15/2014)... 2014 This year, Avenidas Village ... 2007. To mark the special occasion, Avenidas Village would ... village and helping it to get started seven years ... fun community for seniors. Members of Avenidas Village maintain ... in their own homes. They are able to have ...
(Date:9/15/2014)... Maureen Salamon HealthDay ... -- Pediatricians prescribe antibiotics about twice as often as ... infections, a new study indicates. More than 11 ... teens may be unnecessary, according to researchers from University ... use not only fails to eradicate children,s viral illnesses, ...
(Date:9/15/2014)... By Amy Norton ... -- A relatively small number of medications are responsible for ... ingestion, a U.S. government study finds. Each year between ... years were hospitalized after getting a hold of family members, ... Prevention. "Three-quarters of those children were just 1 ...
Breaking Medicine News(10 mins):Health News:EEG study findings reveal how fear is processed in the brain 2Health News:White House Shifts Policy on Drugs 2Health News:Avenidas Village Celebrates Anniversary 2Health News:Kids Prescribed Antibiotics Twice as Often as Needed, Study Finds 2Health News:Kids Prescribed Antibiotics Twice as Often as Needed, Study Finds 3Health News:Small Number of Drugs Behind Kids' Accidental Poisonings: CDC 2Health News:Small Number of Drugs Behind Kids' Accidental Poisonings: CDC 3
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