Mayo Clinic Proceedings: A Comprehensive Review of Addiction to Prescription Painkillers Among Patients and Physicians
... tragedies, of prescription chemical addiction and
abuse are being discussed, these articles offer crucial ... direction and optimism.
Addiction to and
abuse of prescription opioid drugs are prevalent, and ... have the greatest risk of opioid dependence and
abuse among health care providers. Also in the ...
Acura and King Receive FDA Complete Response Letter Regarding Acurox(R)
... Letter raises issues regarding the potential
abuse deterrent benefits of Acurox(R). Acura and King ... Technology, which is designed to deter misuse and
abuse by intentional swallowing of excess quantities of ... product candidates and other innovative
abuse deterrent technologies. Acura and King jointly ...
Classwide Opioids REMS: A Good Idea, Implement Carefully
... patients and non-patients, those who misuse or
abuse the drug and are not prescribed the medication. ...
Will drug abusers shift their
abuse to other licit or illicit substances?
... chronic pain in the effort to prevent misuse and
abuse of these important medications. It would be of ...
American Academy Of Orthopaedic Surgeons 2009 Annual Meeting 'Highlights and Hot Topics'
...
Broken Bones as Indicators of Child
abuse
( ... Seen Between Types of Orthopaedic Injury and
abuse
In a study of nearly 1,500 ... classified as either confirmed victims of child
abuse or sufferers of accidental trauma, clear ...
FDA Approves Tapentadol Immediate-Release Tablets for Relief of Moderate to Severe Acute Pain
... increased risk of misuse, abuse, or diversion.
abuse of tapentadol poses a risk of overdose and death. This risk is increased with concurrent
abuse of tapentadol with alcohol and other substances. Monitor patients closely for signs of
abuse and addiction.
Tapentadol may impair ...
Alpharma Announces Positive Results From Pivotal Phase III Efficacy Trial on ALO-01 (EMBEDA(TM)) (morphine sulfate extended-release with sequestered naltrexone hydrochloride) Capsules at the American Academy of Pain Management Annual Clinical Meeting
... therapies.(2,3A) However, prescription
opioid
abuse has escalated along with increased legitimate use ... relief
while minimizing the potential for misuse,
abuse and diversion.(3B,7)
Study Design
The ... 3. Woolf CJ, Hashmi M. Use and
abuse of opioid analgesics: potential
methods to ...
REMOXY(R) NDA Filing Accepted by FDA and Priority Review Granted
... E. Brown, DVM, President and CEO of
DURECT. "The
abuse of pain medications is a widespread problem in ... with the
added benefit of being less prone to
abuse (e.g. by crushing or water
extraction) than other ... superior
clinical/commercial attributes such as
abuse deterrence, improved
convenience, compliance, ...
Catalyst Pharmaceutical Partners, Inc. Begins Enrollment for U.S. Phase II Clinical Trial of CPP-109 in Patients with Methamphetamine Addiction
... that affects the
central nervous system.
abuse of the drug leads to devastating ... treatment for methamphetamine and other stimulant
abuse in 2006. In
addition, according to the 2006 ... National Drug Control Policy, the costs of
drug
abuse to society were an estimated $180 billion in 2002 ...
Alpharma Presents Data Addressing Abuse Liability Features, Safety and Efficacy on ALO-01 (EMBEDA(TM)) (morphine sulfate extended-release with sequestered naltrexone hydrochloride) at the American Pain Society Annual Scientific Session
... clinically relevant features addressing
abuse liability
alongside a promising safety and ... of ALO-01 when crushed -- a common
method of
abuse -- among recreational drug users and when taken ... "The undertreatment of chronic pain and the
abuse of prescription
opioids are both serious health ...
Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
... and a Schedule II
controlled substance, with an
abuse liability similar to other opioid
analgesics. ... is
concerned about an increased risk of misuse,
abuse or diversion. Schedule
II opioid substances which ... and methadone have the highest potential for
abuse and risk of
fatal overdose due to respiratory ...
SUNY Youth Sports Institute Convenes Top Experts in NYC Next Week to Present Research & Analysis on Energy Drink Health Impacts
... Institute, Philadelphia, PA, Associate Director, Center for Substance
abuse Research, University of Maryland, College Park , MD. One of Dr. Arria's ... Institute, Philadelphia, PA Associate Director, Center for Substance
abuse Research, University of Maryland, College Park , MD
Christina ...
King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use
... triple-action combination of niacin and inactive ingredients reduces its
abuse liability.
About EMBEDA(TM)
EMBEDA(TM) is an investigational ... and there is no evidence that the naltrexone in EMBEDA(TM) reduces the
abuse liability of EMBEDA(TM).
About King Pharmaceuticals, Inc.
King, ...
Study of Cannabinoid Medicine for Pain Found Patients Got 'High,' but Effects Not Related to Pain Relief
... similar to
smoking marijuana, leading researchers to conclude the
abuse potential of this
class should be studied further.
Using the Addiction Research Center Inventory (ARCI), the gold-standard
for determining the
abuse liability of substances, Dr. Wasan and colleagues at
McLean Hospital ...
Advances in Science and Treatment of Pain Presented at 25th Annual American Academy of Pain Medicine Meeting January 28 - 31, 2009
... and brain to effectively treat pain, including medications with decreased
abuse potential."
At this year's meeting, attendees will have access to ... Trauma/Combat Injury, Poster 273
Reduction of Opioid/Illicit Drug
abuse & Electronic
Prescription Monitoring, Poster 274
About ...
Novel Compound Shows Promise for Treatment of Alcoholism
... for the treatment of
alcoholism. The National Institute on Alcohol
abuse and Alcoholism (NIAAA)
estimates 15.1 million people are alcohol-abusing ... by the State of
California for Medical Research on Alcohol and Substance
abuse and
Department of Defense.
Southern Research operates a successful drug ...
Discovering How Video Games Can Motivate Healthy Behaviors: More than $2 Million Awarded to 12 Research Teams Across U.S.
... patients progress faster in physical therapy to how people
in substance
abuse treatment can practice skills and behaviors in the
virtual world of a game ... designed to enable people aged 18 to 65 that are
diagnosed with alcohol
abuse or dependence to practice skills that can help
them prevent real-world ...
Public Forum to Discuss Addiction as a Treatable Disease and Highlight National Alcohol and Drug Addiction Recovery Month
... the national data
on this growing public health problem -- the Substance
abuse and Mental
Health Services Administration (SAMHSA) reports that ... respiratory depression and death. SUBOXONE has potential for
abuse and produces dependence of the opioid
type with a milder withdrawal ...
Nabi Biopharmaceuticals Announces Continued Positive NicVAX Phase 2b Data at Nine Months
... smoking cessation
researchers and the National Institute on Drug
abuse (NIDA). Nabi will use
these validated and promising nine-month data to ... that it received a $4.1 million grant
from the National Institute on Drug
abuse (NIDA), which is part of the
National Institutes of Health. NIDA has also ...
New Study Presented at WorldSleep 2007 Demonstrates Ramelteon Has Sustained Efficacy Over Six Months in Adults With Chronic Insomnia
... first and only prescription sleep medication
that has shown no evidence of
abuse or dependence in clinical studies,* and
has not been designated as a ... the sleep- wake cycle. *ROZEREM is not a controlled substance. A
clinical
abuse liability study showed no differences indicative of abuse
potential ...
GAA Calls on Secretary Clinton to Speak Out Against Gender-Based Violence During Her Africa Trip
... African governments to address the scourge of violence," said Zeitz.
Worldwide, one in three women will survive physical, sexual, or emotional
abuse in her lifetime. One in five will survive rape or attempted rape, and around 50% of female sexual assault survivors are 15 years or younger at the ...
FDA Issues Complete Response Letter for INTUNIV(TM) (guanfacine) Extended Release for the Treatment of ADHD in Children and Adolescents
... of guanfacine, designed to provide steady delivery of drug
throughout the day. INTUNIV is not a controlled substance and has no known
potential for
abuse or dependence.
Guanfacine, the active ingredient in INTUNIV, is thought to work directly
by binding selectively to alpha-2A adrenergic ...
PTSD Associated With Higher Alzheimer's/Dementia Risk; Moderate Alcohol Consumption May Lower it
... veterans without PTSD (HR = 1.8, 95% CI 1.7-1.9). Results were similar when they excluded those with a history of traumatic brain injury, substance
abuse or depression.
"It is critical to follow patients with PTSD, and evaluate them early for dementia," Yaffe said. "Further research is needed ...
Conatus Pharmaceuticals Initiates a Second Phase 2 Clinical Trial for the Treatment of Hepatitis
... and can be caused by many different conditions or "insults" to the liver including Hepatitis C and other viral infections, obesity, chronic alcohol
abuse or autoimmune diseases. Conatus was founded by the executive management team of Idun Pharmaceuticals in July 2005 following the successful sale of ...
Blanchette Rockefeller Neurosciences Institute and Inverness Medical Innovations to Develop Commercial Test to Detect Early Alzheimer's Disease
... diagnostics, Inverness' products, as well as its new product development efforts, focus on infectious disease, cardiology, oncology, drugs of
abuse and women's health. Inverness is headquartered in Waltham, Massachusetts.
...
New Phase 3 Study of Tapentadol Immediate Release Tablets Published in Current Medical Research and Opinion Journal
... is concerned about an increased risk of misuse and abuse. All patients treated with mu-opioid agonists require careful monitoring for signs of
abuse and addition. NUCYNTA(TM) may be abused by crushing, chewing, snorting or injecting the product. These practices pose a significant risk to the ...
New Study Evaluating the ADHD Medication VYVANSE(R) (lisdexamfetamine dimesylate) CII Demonstrated No Change in the Pharmacokinetic Profile of VYVANSE When Coadministered with Prilosec OTC(R) 40 mg (20 mg X 2), a Commonly Used Proton Pump Inhibitor (PPI)
... Tell the doctor immediately if you or your child develops any of these conditions or symptoms while taking Vyvanse or Adderall XR.
abuse of amphetamines may lead to dependence. Misuse of amphetamine may cause sudden death and serious cardiovascular adverse events. These events have ...
Shire Announces Study Results of the Effects of INTUNIV(TM) (Guanfacine) Extended Release on Secondary Measures in Children with ADHD and Oppositional Symptoms
... clinical trials, INTUNIV demonstrated significant reduction in ADHD symptoms. INTUNIV is not a controlled substance and has no known mechanism for
abuse or dependence.
Guanfacine, the active ingredient in INTUNIV, is thought to work directly by binding selectively to alpha-2A adrenergic receptors ...
One Step Closer: Novel Opioid Receptor Compound in Phase I Clinical Trials
... leading to Wentland's latest discovery was funded in 1999 through a $826,000 grant from the National Institutes of Health/National Institute on Drug
abuse (NIH-NIDA) in an effort to discover novel drugs to treat cocaine abuse. In 2002, Wentland's NIH grant was renewed for an additional $1.6 million, and ...
DURECT Reports Positive Phase IIb Data from TRANSDU(TM)-Sufentanil Clinical Program
... oral, transdermal and injectable depot delivery technologies may enable new indications and superior clinical/commercial attributes such as
abuse deterrence, improved convenience, compliance, efficacy and safety for small molecule and biologic drugs. For more information, please visit ...
Shire Withdraws European Application for DAYTRANA(TM) (Methylphenidate Transdermal System)
... or hostility. Tell the doctor immediately if you or your child
develops any of these conditions or symptoms while taking Vyvanse.
abuse of amphetamines may lead to dependence. Misuse of amphetamine may
cause sudden death and serious cardiovascular adverse events. These events
have ...
Premier Research Announces Milestone New Drug Application
... relief of moderate to severe pain. Acurox(R) utilizes Acura Pharmaceuticals' patented Aversion(R) Technology, which is designed to deter misuse and
abuse by intentional swallowing of excess quantities of tablets, intravenous injection of dissolved tablets and nasal snorting of crushed tablets.
...
Study Shows Leconotide, an Investigative Calcium Channel Blocker, Has Potential as a Selective, Efficacious, Non-Opioid Pain Treatment
... are exciting for researchers in the field
of pain medicine, doctors whom treat pain, and patients who suffer or are
under-treated because of the
abuse potential and side effects associated with
opioid treatments," said Colin Goodchild, PhD, and director of the Centre for
Pain Research and Palliative ...
Cara Therapeutics Initiates Phase II Proof-Of-Concept Trial of Novel Analgesic in Acute Post-Operative Pain
... in multiple species. In contrast to currently marketed opioids, CR845 did not produce inhibition of intestinal transit (ileus) or elicit signs of
abuse or addiction liability in animal models. Preclinical studies also indicate that CR845 possesses anti-itch activity.
About Cara Therapeutics
...
Recent Study Demonstrated VYVANSE(R) (lisdexamfetamine dimesylate) CII Provided Improvements in Behavior, Inattention, and Math Test Scores from 1.5 Hours up to 13 Hours following Administration in Children with ADHD
... or hostility. Tell the doctor immediately if you or your child
develops any of these conditions or symptoms while taking Vyvanse.
abuse of amphetamines may lead to dependence. Misuse of amphetamine may
cause sudden death and serious cardiovascular adverse events. These events
have ...
Inverness Medical Innovations Participates in Meeting on HIV/AIDS with UN Secretary-General
... diagnostics, Inverness' products, as well as its new
product development efforts, focus on infectious disease, cardiology,
oncology, drugs of
abuse and women's health. Inverness is headquartered in
Waltham, Massachusetts.
For more information about Inverness Medical Innovations, please ...
Study Published in Journal of Clinical Psychiatry Showed Once-Daily VYVANSE(R) (lisdexamfetamine dimesylate) Significantly Improved ADHD Symptoms in One of the Largest Controlled Stimulant Trials in Adults with ADHD
... or hostility. Tell the doctor immediately if you or your child
develops any of these conditions or symptoms while taking Vyvanse.
abuse of amphetamines may lead to dependence. Misuse of amphetamine may
cause sudden death and serious cardiovascular adverse events. These events
have ...
Cephalon Receives Complete Response Letter Regarding Request for Expanded FENTORA Label for Non-Cancer Breakthrough Pain
... prescribed FENTORA are opioid-tolerant. Additionally, the company
will continue to enhance its existing programs to mitigate risks associated
with
abuse and misuse.
FENTORA is currently approved for the management of breakthrough pain
in opioid-tolerant patients with cancer (for full prescribing ...
Pediatric Heart Transplants at Montefiore Approved by NY State Department of Health
... a key provider of community-based care through its network
of 16 school-based clinics, the Child Advocacy Center for diagnosis and
treatment of child
abuse and neglect, a Safe House for lead poison
prevention, mobile pediatric centers and other unique initiatives.
...
Inverness Medical Innovations Receives USDA Licensure of the BinaxNOW(R) Avian Influenza Virus Type A Antigen Test Kit
... diagnostics, Inverness' products, as well as its new
product development efforts, focus on infectious disease, cardiology,
oncology, drugs of
abuse and women's health. Inverness is headquartered in
Waltham, Massachusetts.
For more information about Inverness Medical Innovations, please ...
ELADUR(TM) Development Update: DURECT Receives Orphan Drug Designation for Bupivacaine for Post-Herpetic Neuralgia
... proprietary oral, transdermal and
injectable depot delivery technologies enable new indications and superior
clinical/commercial attributes such as
abuse deterrence, improved
convenience, compliance, efficacy and safety for small molecule and
biologic drugs. For more information, please visit ...