AcelRx Announces Positive Phase 2 Results from a Study of ARX-01 Sufentanil NanoTabs in Treating Post-Operative Pain
... Study in major
abdominal surgery patients achieved primary and secondary ... management of post-operative pain following major
abdominal surgery reported statistically significant ... study included 88 patients undergoing major
abdominal surgery randomized to receive either 10 mcg or 15 ...
Ironwood and Forest Present Additional Positive Phase 2b Study Results for Linaclotide in Patients With Irritable Bowel Syndrome With Constipation
... Demonstrate Linaclotide Provided Early Onset of
abdominal Pain Relief and Improved Bowel Habits --
... across a range of doses, significantly improved
abdominal symptoms, bowel habits, and global assessments ... a statistically significant improvement in
abdominal symptoms, bowel habits, and global assessments ...
Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types
... identified in clinical studies include nausea,
abdominal pain, gas, constipation, vomiting, pain on ... fatigue, stomatitis, dehydration, pneumonitis,
abdominal pain and asthenia. The most common laboratory ... superficial edema (6%; 5%), hemorrhage (6%; 11%),
abdominal pain (11%; 4%), nausea (6%; 4%), diarrhea (3%; ...
New Study Shows Probiotic Strain Effective in Improving Irritable Bowel Syndrome Symptoms
... Bacillus coagulans significantly reduces
abdominal pain and bloating
CLEVELAND, March 24 ... GBI-30, PTA-6086 was effective in relieving
abdominal pain and bloating in subjects with irritable ... statistically significant reductions in
abdominal pain and bloating versus baseline at each of the ...
Continued Overall Survival Advantage Reported From Pivotal Trial of VELCADE(R) (Bortezomib) for Injection Based Therapy in Patients With Previously Untreated Multiple Myeloma
... (excluding vertigo) (each 17%), pain in limb and
abdominal pain (each 15%), bone pain (14%), back pain and ... (14% vs 10%), pain in extremity (14% vs 9%),
abdominal pain (14% vs 7%), paresthesia (13% vs 4%), herpes ... (13% vs 7%), hypertension (13% vs 7%),
abdominal pain upper (12% vs 9%), hypotension (12% vs 3%), ...
Prolonged Progression-Free Survival Demonstrated by VELCADE(R) (Bortezomib) for Injection Based Induction Regimens in Transplant-Eligible Previously Untreated Multiple Myeloma Patients
... vertigo) (each 17%), pain in limb and
abdominal pain (each 15%),
bone pain (14%), back pain and ... (14% vs 10%), pain in
extremity (14% vs 9%),
abdominal pain (14% vs 7%), paresthesia (13% vs 4%),
herpes ... (13% vs 7%),
hypertension (13% vs 7%),
abdominal pain upper (12% vs 9%), hypotension (12%
vs 3%), ...
Novel VELCADE(R) (Bortezomib) for Injection Based Four-Drug Combination Was Well Tolerated In Previously Untreated Multiple Myeloma Patients
... vertigo) (each 17%), pain in limb and
abdominal pain (each 15%),
bone pain (14%), back pain and ... (14% vs 10%), pain in
extremity (14% vs 9%),
abdominal pain (14% vs 7%), paresthesia (13% vs 4%),
herpes ... (13% vs 7%),
hypertension (13% vs 7%),
abdominal pain upper (12% vs 9%), hypotension (12%
vs 3%), ...
Long-Term Study Evaluates Boosted PREZISTA(R) Vs. Lopinavir/Ritonavir as Part of HIV Combination Therapy in Treatment-Naive Adults
... were diarrhea (6
percent), headache (5 percent),
abdominal pain (4 percent), nausea (3
percent), vomiting (2 ... were diarrhea (12 percent), nausea (7 percent),
abdominal pain (5
percent), rash (6 percent), vomiting (4 ... asthenia (3 percent),
headache (2 percent),
abdominal distension (2 percent), and dyspepsia ....
Ironwood and Forest Present Positive Phase 2b Study Results for Linaclotide in Patients With Irritable Bowel Syndrome With Constipation
... across a range of
doses, significantly reduced
abdominal pain and significantly improved
constipation ... The results of this study showing improvement in
abdominal pain
and constipation are encouraging," said ... of patients with severe/very severe
baseline
abdominal pain, improvement was even more pronounced (-0.8 ...
Ironwood and Collaborators Present Preclinical Data Demonstrating That Cyclic GMP Alleviates Intestinal Pain
... in patients with IBS-C, linaclotide reduced
abdominal pain and
improved bowel habits. The detailed ... CC. In patients with IBS-C, linaclotide reduced
abdominal pain and
relieved constipation-the hallmarks of ... suffers from IBS, a
chronic condition marked by
abdominal pain and disturbed bowel function.
IBS accounts ...
Ironwood and Forest to Present Positive Data From Linaclotide Phase 2b IBS-C Study at ACG Annual Scientific Conference
... at
all linaclotide dose levels. Notably,
abdominal pain was clinically and
statistically ... in patients with IBS-C, linaclotide reduced
abdominal pain and
relieved constipation-the hallmarks of ... suffers from IBS, a
chronic condition marked by
abdominal pain and disturbed bowel function.
IBS accounts ...
AstraZeneca Submits sNDA for NEXIUM(R) I.V. for Peptic Ulcer Bleed Indication
... with NEXIUM
include headache, diarrhea, and
abdominal pain. In patients 1 to 17 years
of age, the most ... reactions with NEXIUM include
headache, diarrhea,
abdominal pain, nausea, and somnolence. ... with NEXIUM include
headache, diarrhea, and
abdominal pain. Injection site reactions have also
been ...
Ironwood Pharmaceuticals and Forest Laboratories Announce Presentation of Linaclotide Phase 2b Chronic Constipation Study Results
... stool
consistency, straining, bloating,
abdominal discomfort, and severity of
constipation. ... outcomes included measures of
abdominal pain, abdominal
discomfort, and bloating on a ... suffers from IBS, a
chronic condition marked by
abdominal pain and disturbed bowel function.
IBS accounts ...
New Analysis Shows Efficacy of REMICADE(R) in Treatment of Ulcerative Colitis in Patients with Recent Disease Onset or Long-Standing Disease
... bloody
stools, severe diarrhea and frequent
abdominal pain. Tiny open sores, or
ulcers, form on the ... of Crohn's disease can vary but often
include
abdominal pain and tenderness, frequent diarrhea, rectal ... skin and eyes), dark brown urine, right-sided
abdominal pain, fever
or severe fatigue.
Blood disorders ...
New AMITIZA 8 mcg Phase III Studies Demonstrated Overall Symptom Improvement in Adult Women with Irritable Bowel Syndrome with Constipation (IBS-C)
... IBS-C is a
chronic disorder characterized by
abdominal discomfort or pain and changes
in bowel habits ... associated with
constipation, the presence of
abdominal discomfort or pain is what
differentiates IBS-C ... nausea (29%), diarrhea (12%), headache (11%),
abdominal pain (8%),
abdominal distention (6%), and ...
Cadence Pharmaceuticals Reports First Quarter 2008 Financial Results and Provides Clinical Program Update
... the treatment of acute pain in adults following
abdominal laparoscopic surgery. The trial design ... III Completed Treatment of pain following
abdominal gynecologic surgery 301 ... I Completed Treatment of pain following
abdominal laparoscopic surgery 304 ...
Microbia and Forest Laboratories Announce Preliminary Results of Linaclotide Phase 2b Studies
... (CSBM) frequency, stool
consistency, straining,
abdominal pain, bloating, and abdominal
discomfort-that ... stool consistency,
abdominal pain, bloating,
abdominal discomfort, adequate relief, and IBS-C
symptom ... outcomes included measures of
abdominal pain,
abdominal discomfort, and bloating on a daily basis, ...
CSL Behring Reaches Primary Endpoint in Clinical Study of C1-INH for Treatment of Hereditary Angioedema
... lead to
faster relief of acute symptoms of
abdominal and facial attacks compared
with placebo in ... deficiency
and a documented history of facial or
abdominal attacks.
The primary objective was to show that ... the time to
onset of relief of symptoms of
abdominal or facial HAE attacks. The primary
endpoint was ...
New Analysis of Study Data Shows That Asacol(R) (Mesalamine) Delivers Rapid Symptom Relief for Ulcerative Colitis Patients
... symptoms such
as diarrhea, rectal bleeding,
abdominal cramping and an urgent need to go
to the ... respectively, were headache
(35% vs. 36%),
abdominal pain (18% vs. 14%), eructation (16% vs. 15%), ... rhinitis
(42% vs. 36%), diarrhea (35% vs. 50%),
abdominal pain (32% vs. 44%) and
flatulence (24% vs. 30%). ...
AspenBio Pharma Reports Strong Results with Appendicitis Triage Blood Test from Large Multiple Hospital Study
... who presented to the emergency
rooms with
abdominal pain, with appendicitis as a possible diagnosis. ... of the AppyScore test in patients with
abdominal pain may exceed
the boundaries of patients with ... enter
hospital emergency rooms complaining of
abdominal pain and who could
potentially have appendicitis. ...
Procter & Gamble Pharmaceuticals Launches Asacol(R) HD (mesalamine) Delayed-Release Tablets
... inflamed, people experience symptoms such as diarrhea, rectal bleeding,
abdominal cramping and an urgent need to go to the bathroom. Flares can vary in ... in patients treated with Asacol and Asacol HD were nausea, diarrhea,
abdominal pain, eructation, flatulence, exacerbation of UC, headache, rhinitis, ...
New One-Year Data from REMICADE(R) SONIC Trial Show Sustained Efficacy Compared with Azathioprine in Treatment of Crohn's Disease
... factors. Symptoms of Crohn's disease can vary but often include
abdominal pain and tenderness, frequent diarrhea, rectal bleeding, weight loss and ... injury - jaundice (yellow skin and eyes), dark brown urine, right-sided
abdominal pain, fever, or severe tiredness.
Blood disorders - fever that ...
Shire Announces Study Results of the Effects of INTUNIV(TM) (Guanfacine) Extended Release on Secondary Measures in Children with ADHD and Oppositional Symptoms
... than or equal to 10 percent) were somnolence, headache, sedation, upper
abdominal pain, fatigue and irritability. The majority of treatment emergent ... (32 percent), headache (26 percent), fatigue (18 percent), upper
abdominal pain (14 percent) and sedation (13 percent). Syncope occurred in ...
Ironwood Announces Linaclotide European Licensing Agreement with Almirall
... IBS-C or CC. In patients with IBS-C, linaclotide significantly reduced
abdominal pain and bloating and improved bowel function throughout the 12-week ...
IBS-C is a chronic functional gastrointestinal disorder characterized by
abdominal pain and discomfort associated with altered bowel habits. There are ...
Nektar Announces Positive Results from Phase 2 Study of Oral NKTR-118 in Patients with Opioid-Induced Constipation (OIC)
... study that led to discontinuation of medication were diarrhea, nausea and
abdominal cramping. These side effects were most frequent in the 50 mg dose group. ... complex resulting from opioid use that encompasses constipation, bloating,
abdominal cramping, and gastroesophageal reflux. Constipation is the hallmark of ...
Gallbladder Removal Through Vagina Offers Minimally Invasive Alternative
... the surgery. "NOTES reduces the number of and may eliminate the need for
abdominal incisions compared with traditional laparoscopic surgery, and may reduce ... 2. Lamb, diagnosed with gallstone disease, had been experiencing severe
abdominal pain for weeks that was not responding to dietary changes, and surgery was ...
Study Results Show Epratuzumab Provided Clinically Meaningful Reduced Disease Activity in Patients With Lupus
... compared to
placebo treatment: arthralgia, sinusitis, nausea, pyrexia,
abdominal pain,
oral candidiasis, peripheral edema, chest pain, pharyngolaryngeal pain,
rash,
abdominal pain upper, and cough. Serious infections (serious adverse
events that ...
Early Data Show Potential for Imatinib Mesylate Tablets to Treat Life-Threatening Form of Pulmonary Artery Disease
... or ascites; 3%; 8%) and superficial edema (6%; 5%), hemorrhage
(6%; 11%),
abdominal pain (11%; 4%), nausea (6%; 4%), diarrhea (3%; 7%) and
musculoskeletal ... 74%), muscle cramps (47%; 58%), diarrhea (59%;
70%), fatigue (48%; 53%),
abdominal pain (40%; 37%), rash and related terms
(38%; 53%), vomiting (38%; 35%), ...
New Findings Show Efficacy of REMICADE(R) Compared With Azathioprine in Treatment of Crohn's Disease According to First-of-its Kind Study
... factors. Symptoms of Crohn's disease can vary but often
include
abdominal pain and tenderness, frequent diarrhea, rectal bleeding,
weight loss and ... such as jaundice
(yellow skin and eyes), dark brown urine, right-sided
abdominal pain, fever
or severe fatigue.
Blood disorders have been reported, some ...
New England Journal of Medicine Publishes Phase III Results of VELCADE(R) (Bortezomib) for Injection in Previously Untreated Multiple Myeloma Patients
... (15% vs 13%),
headache (14% vs 10%), pain in extremity (14% vs 9%),
abdominal pain (14%
vs 7%), paresthesia (13% vs 4%), herpes zoster (13% vs 4%), bronchitis (13%
vs 8%), hypokalemia (13% vs 7%), hypertension (13% vs 7%),
abdominal pain
upper (12% vs 9%), hypotension (12% vs 3%), dyspepsia (11% vs ...
Abbott's Kaletra(R) Tablet Dosed Once-Daily or Twice-Daily Demonstrated Similar Clinical Results Across Race and Gender Lines
... side effects of moderate severity that are
thought to be drug related are
abdominal pain, abnormal bowel movements,
diarrhea, feeling weak/tired, headache and ... Patients should tell their doctor if they
have nausea, vomiting, or
abdominal pain, which may be signs of
pancreatitis, or if they have or have had ...
New England Journal of Medicine Publishes Results From a RELISTOR Phase 3 Clinical Study
... generally well tolerated. The most
frequently reported adverse events were
abdominal pain and flatulence.
Full study results from this first published ... most common adverse reactions with RELISTOR in clinical trials were
abdominal pain, flatulence, and nausea.
RELISTOR Prescribing Information is ...
Imaging Results From the ADAGIO-LIPIDS Reveal That Effects of Rimonabant on Cardiometabolic Risk Profile Include Loss of Visceral Fat and Mobilization of Liver Fat
... that the most prevalent form of the metabolic syndrome is
associated with
abdominal obesity, particularly with an excess of visceral
fat as well as with ... system could induce a reduction in waist circumference (a
crude marker of
abdominal fat) and improve several features of the
metabolic syndrome, no study had ...
Presentation of HeartWare Clinical Results
... size, which allows it to be implanted in the chest, thereby avoiding
the
abdominal surgery generally required to implant competing devices.
HeartWare CEO ... is a full-output pump designed to be implanted in the
chest, avoiding the
abdominal surgery generally required to implant
competing devices. The device is ...
Tart Cherries May Reduce Inflammation, Lower Risk for Type 2 Diabetes & Heart Disease
... and total fat mass -- particularly important given the link between
excess
abdominal fat and disease.
Researchers say the animal study is encouraging and ... .
Source: Tart Cherry-Enriched Diets Reduce
abdominal Obesity and
Inflammation in Zucker Fatty Rats. Experimental Biology 2008 ...
CSL Behring Submits BLA Requesting Approval of C1-Esterase Inhibitor for the Treatment of Hereditary Angioedema
... and feet, the face, the abdomen, and/or the
larynx. Patients who have
abdominal attacks can experience episodes of
severe pain, diarrhea, nausea, and ... is based on a study of 124 HAE patients with acute,
moderate, or severe
abdominal or facial attacks. C1-INH concentrate was
administered at two different ...
Not Only Lipids and Inflammation: Insight Into a New Cause of Heart Attack and Other Vascular Disease
... risk of heart attack is also associated with up to 70%
increase in risk of
abdominal aortic aneurysm (AAA) and intracranial
aneurysm (IA). This is the first ... 'The same sequence
variant on 9p21 associates with myocardial infarction,
abdominal aortic
aneurysm and intracranial aneurysm,' is published today in the ...
Study Data Show Asacol(R) (Mesalamine) is Effective in Treating All Extents of Ulcerative Colitis Including Isolated Proctitis
... inflamed, people experience symptoms such
as diarrhea, rectal bleeding,
abdominal cramping and an urgent need to go
to the bathroom. Flares can vary in ... and placebo, respectively, were headache
(35 percent vs. 36 percent),
abdominal pain (18 percent vs. 14 percent),
eructation (16 percent vs. 15 percent), ...
New England Journal of Medicine Study Shows ERBITUX(R) Improves Survival in Advanced Colorectal Cancer
... either group) adverse events of
any grade were rash/desquamation, fatigue,
abdominal pain, other pain, dry
skin, dyspnea, constipation, pruritus, diarrhea, ... respectively, were fatigue (89%, 76%),
rash/desquamation (89%, 16%),
abdominal pain (59%, 52%), pain-other (51%,
34%), dry skin (49%, 11%), dyspnea (48%, ...
Review of Probiotic Trial Research Finds Only Bifantis(R) Able to Claim Efficacy versus Placebo for IBS Symptoms
... infantis 35624 showed significant improvement in the
composite score of
abdominal pain/discomfort, bloating/distention and bowel
movement difficulty ... superior efficacy to the
placebo for the primary outcome measure of
abdominal pain/discomfort as
well as for secondary measures including ...